Basic Information

Insect: Yponomeuta rorrellus
Gene Symbol: ZEB2
Assembly: GCA_947308005.1
Location: OX371023.1:1591256-1622412[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.33 24 6.2 3.0 1 23 5 28 5 28 0.94

2 15 0.0001 0.0074 17.2 0.2 1 23 34 57 34 57 0.95

3 15 8.2e-06 0.0006 20.7 3.1 2 23 70 91 69 91 0.97

4 15 0.00096 0.07 14.2 0.1 1 23 97 120 97 120 0.96

5 15 0.0026 0.19 12.8 1.7 1 23 574 597 574 597 0.96

6 15 6.5e-06 0.00047 21.0 1.0 1 23 603 626 603 626 0.93

7 15 3.9e-08 2.8e-06 28.0 0.7 1 23 634 656 634 656 0.99

8 15 0.018 1.3 10.1 1.0 1 23 663 686 663 686 0.94

9 15 0.52 38 5.6 1.0 1 23 912 936 912 936 0.90

10 15 0.0002 0.014 16.3 1.5 1 23 943 965 943 965 0.98

11 15 1.1 80 4.5 0.3 1 20 1005 1024 1005 1026 0.92

12 15 0.023 1.7 9.8 4.8 1 20 1030 1049 1030 1052 0.94

13 15 0.00018 0.013 16.5 2.6 2 22 1061 1081 1060 1085 0.92

14 15 1.6 1.2e+02 4.0 4.2 1 23 1093 1116 1093 1116 0.86

15 15 0.56 41 5.5 0.2 1 11 1122 1132 1122 1134 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.33	24	6.2	3.0	1	23	5	28	5	28	0.94
2	15	0.0001	0.0074	17.2	0.2	1	23	34	57	34	57	0.95
3	15	8.2e-06	0.0006	20.7	3.1	2	23	70	91	69	91	0.97
4	15	0.00096	0.07	14.2	0.1	1	23	97	120	97	120	0.96
5	15	0.0026	0.19	12.8	1.7	1	23	574	597	574	597	0.96
6	15	6.5e-06	0.00047	21.0	1.0	1	23	603	626	603	626	0.93
7	15	3.9e-08	2.8e-06	28.0	0.7	1	23	634	656	634	656	0.99
8	15	0.018	1.3	10.1	1.0	1	23	663	686	663	686	0.94
9	15	0.52	38	5.6	1.0	1	23	912	936	912	936	0.90
10	15	0.0002	0.014	16.3	1.5	1	23	943	965	943	965	0.98
11	15	1.1	80	4.5	0.3	1	20	1005	1024	1005	1026	0.92
12	15	0.023	1.7	9.8	4.8	1	20	1030	1049	1030	1052	0.94
13	15	0.00018	0.013	16.5	2.6	2	22	1061	1081	1060	1085	0.92
14	15	1.6	1.2e+02	4.0	4.2	1	23	1093	1116	1093	1116	0.86
15	15	0.56	41	5.5	0.2	1	11	1122	1132	1122	1134	0.92

Sequence Information

Coding Sequence: ATGTTGTTGCTACACGAGTGCCCGCACTGCCAACTTCGGTTCCACATCGCCCAGCGACTGAAGGAACACATCGCCGTGAAGCATCTAAACAGAGGACTCTACGCCTGTGATATGTGCCCGAAAAGCTATACAGTGAACGTAAGTCTGCGCAAACATCGCGCCCGGGTCCATAACATCGGCTCTGTCCGAGCGCCGGCGCGGGACAAAGTGTGCGACCACTGCGGGAAGGCTTTCACGTCCAACCATCTCCTTAACAACCACGTGCGTCTCCACACGGGCGAGAAGCCGTTCAAGTGTCCCCTGTGCCCCGCCGCCTTCGCTCAGAACGGCACCCTGTATATGCATACGCTGAGCGTTCACCGGAAGAAGCTGAGCAAAGATGGCGCTGGCGATAGTACCGAGGACGCCCCTAAAATGATGACCAGGGGCAAGTCGAGTGCACGAGATATGGAGCTGAGGCTGAAGGCCACCCTGATGGAGCTTAAAGCGAGCAAAGAACTTTGCAACACACTTCTACAAGAACGGGAGGAGAGTGAGGAGGAGATCCAGAAGCAAAACAAGAAGACTTTGGCACTCAAAGAAGAACTGAATGAGTTAGATATCAAGTGCCAAGATCTCACTGGTCAACGTGATGAGCTACAACGACAAGTCGACTCGTTTTACAAGTGCCACAACACTCACGACTTGGCCCTACAACGGATCCGCTCGCTAGAACATCAGCTCGGAGAGGCTCATCATGAGCTTCAACTAATCAGTGACCGGGAAGAAAAACAAGAACAAGCTAACACCATGGCTCTCTATAAAGAGGTAATGAGCGACGCCGGCATACTGACAATAGACATCACCTCAACCAGCGAGAAGTCCTGCCATTCAGACAATAAAAGTCATGTGACTATGAGTAGTGCAAATAAAATAAAGAAATACATAAAAACCAACAGATACATAAAGAAGGTGCAAAAACTTGTTAAGAAAGGCCGTAAAAGCCTTAATAACTTGCCCATCCACTATCAAAAAATCCAACTAGCAACCCAAGTGGCTGATTGTCAGAAAGAACTTGTCACTAGCAAAGTTGACCACGAGCTTGCTACAGCGGAACTACAATCTCAAGTTGAAGACCTACAGTTACAATTAATTGATATCACATACAAGTATTCGGCTCTACAAACACAATATGATGACTGCATCCCGATGATGAATGGTTTGATTGCGCTTAGCAAGAGTAATCTAGAACGTGTGGAGTCTAACTTGGACAACTCCGAAGAAGGACTGTTGCTGCCGTCTCTGTCACCAGTGTGCAACGTATCTGGAGATGAGGCCTCTCTACAGCCAACCTCCATGGAGACACGAAACATCGAGGCAAGTGGGCACTCATGCCTGATACCGTCCCTGGGCATCGCTGACCAACCAGCTACTGTACAGCTGGATCCTGCGTGCTGGCATGGGGCGGAGCCAGGCAGTCTGCCTGCAGCAGTAACTGCACCAGAGCGGAGCAGCACCACACCGACCCCTGATGCCATACTAGATGGACAGCCGCAGTCTCAACCTACCAGCTGCAAAGTTCCTGACAATGACACCCAGCACAAAACAGTTATCTACTCAGATAAAATAGGTGTAGGCTTAGGCAGTAGAGTGCAAAACAATTTGAAGCAACATGTAGAGAATATATGTATGCCCTATGCATCTTACATGCAGATAGTGAACTGCATGCTGCGTAAGGATTACCAATGCGAGGAGTGCGGCAAAGGCTTCTGGTCCAGTTCACAGCAGAGGGCTCACCATAAGCTCTTTCACCTCAAACAAAGCAACTTCACCTGCGAAGTGTGCAATAAGATGTTCGCGTCTTCCAGTCACCTCAAGGACCACTTAGCGGGCCGGCACGGCGTGCTTTACAGTGACAGCTTCAAGTGCGACACTTGCGGGAAGCGGTTCAACACCCCTTCAGCGCTCCGCGTCCACATAAAAACCCACTCGGCCGAGACCAGTCTCCACAAATGCCGCGCCTGCGACGCCGCCTTCCGCAACCCCGGGCAGCTGTACGTGCATTTTAAGCTGAAGCATTTGAAGCTAAAAAGGGGCGACAAATTCGTCAAGTACCTGCAAGCGGAAGGCAAGCTACGAGCCTGCTGGCATTGCCACGCTCGCATCAGGAACTTCGCAAACTTCGCCGTCACTGCTCAGAAAAGCGTACATATACTCAAGGATTACTTGAACACGGTTCACAATGAGGTCCCACCGTCATCGGAGACCAGCCTTTGCGTCACAGAACTGGAGCTGGTGAACATAGCTCCTTTCCCTTTAAAGCCGGAGCCCGAACAGAGAAGTGACTTGCTGGCTAAGAACGAGCCGCAAATAGCGCCCGATCTTGGTTACGAGCTCCCGCTTTCGAAAGATGAAATCAAACTCGAAGGTGATTTTTTAGACGATATCGGTTCTGACGGAGACCTACCGGCTGAGGATGAGGATGAAAAAGAAGCGTTAAAAAAGGAGAAGATCCCAGAAAAGGAGAAAGTCTCGCATGAAGCAGCGCGGAAGAAAGTCAGGAAGGAAGTTGCCGCCAAGAAAAAGGTCGTCAAGAAGAGGAACTCCAAGCTCGCAAGAACCAGAAGCGAGAGAGAGAAATCCAAACGGAGCGCCAAGAAGCAGAAAGACCTCTGCTGGTCGGTCCGGTGGGTCACCAACGAGAAGGCGACCAGCTGGTACGAGGAGGAGCGCGCCGGCGAGACGCCCGGCAACTTCGTCTGCGCGCAGTGCAAGCGGACCACCTTCGCCACCGAAGAGGACCTCGTGAGGCACCATACTGAACAGCACGACGAATTAGTCGGCGAGTACCAGTGCAATTTATGCAAATATAGATACGGGACGCTGTCCACACTCCGGCAGCATATCGAGCGTCACTTCATAGAGTACTATTGCCGGGAATGCGAATTCCAGGCGAGGGCTATCAAAGCTATCAAGGACCACTGTAGCGAGGCGCACGAAGTCCGCGTCAGAAGGCGGACCAAGCCCACCTCTTACTTGTGTAAAAGGTGTAAGGATACTTTTCCGACCTTCGCCTTGCTCCGCGAGCACCGCCTGGACTGCAGTACGTACAAATGTGCCAAGTGTGAGAAGACTTTTAAGAACAAGTGCACTTATTTCGACCACCTGCCGCTGCATAAGGAAGGAGCTAAGGAGAAGCTCTATTGCCATATCTGCGACAAACAGTTCACGAGCGCCAGTTGGTTCAAGACACACTTCCGTACCAGTTTGAAGCATGTTTCGAGGGACACCTTCCAACACGAGTGCCCCCACTGTCACATGCGCTTCCACATCGCCCAGCGCCTGAAAGAGCACGTCGCCGCTAAGCATCTCAACAGAGGACTCTACGCCTGCGATCTGTGTCCCAAGAGTTTCACCGGTGAGTGTTAG
Protein Sequence: MLLLHECPHCQLRFHIAQRLKEHIAVKHLNRGLYACDMCPKSYTVNVSLRKHRARVHNIGSVRAPARDKVCDHCGKAFTSNHLLNNHVRLHTGEKPFKCPLCPAAFAQNGTLYMHTLSVHRKKLSKDGAGDSTEDAPKMMTRGKSSARDMELRLKATLMELKASKELCNTLLQEREESEEEIQKQNKKTLALKEELNELDIKCQDLTGQRDELQRQVDSFYKCHNTHDLALQRIRSLEHQLGEAHHELQLISDREEKQEQANTMALYKEVMSDAGILTIDITSTSEKSCHSDNKSHVTMSSANKIKKYIKTNRYIKKVQKLVKKGRKSLNNLPIHYQKIQLATQVADCQKELVTSKVDHELATAELQSQVEDLQLQLIDITYKYSALQTQYDDCIPMMNGLIALSKSNLERVESNLDNSEEGLLLPSLSPVCNVSGDEASLQPTSMETRNIEASGHSCLIPSLGIADQPATVQLDPACWHGAEPGSLPAAVTAPERSSTTPTPDAILDGQPQSQPTSCKVPDNDTQHKTVIYSDKIGVGLGSRVQNNLKQHVENICMPYASYMQIVNCMLRKDYQCEECGKGFWSSSQQRAHHKLFHLKQSNFTCEVCNKMFASSSHLKDHLAGRHGVLYSDSFKCDTCGKRFNTPSALRVHIKTHSAETSLHKCRACDAAFRNPGQLYVHFKLKHLKLKRGDKFVKYLQAEGKLRACWHCHARIRNFANFAVTAQKSVHILKDYLNTVHNEVPPSSETSLCVTELELVNIAPFPLKPEPEQRSDLLAKNEPQIAPDLGYELPLSKDEIKLEGDFLDDIGSDGDLPAEDEDEKEALKKEKIPEKEKVSHEAARKKVRKEVAAKKKVVKKRNSKLARTRSEREKSKRSAKKQKDLCWSVRWVTNEKATSWYEEERAGETPGNFVCAQCKRTTFATEEDLVRHHTEQHDELVGEYQCNLCKYRYGTLSTLRQHIERHFIEYYCRECEFQARAIKAIKDHCSEAHEVRVRRRTKPTSYLCKRCKDTFPTFALLREHRLDCSTYKCAKCEKTFKNKCTYFDHLPLHKEGAKEKLYCHICDKQFTSASWFKTHFRTSLKHVSRDTFQHECPHCHMRFHIAQRLKEHVAAKHLNRGLYACDLCPKSFTGEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -