Basic Information

Insect: Yponomeuta padella
Gene Symbol: CTCF
Assembly: GCA_947311075.1
Location: OX371229.1:942771-960105[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00033 0.022 15.7 2.6 1 23 189 211 189 211 0.98

2 11 6.6e-05 0.0044 17.9 0.8 1 23 217 239 217 239 0.98

3 11 0.00035 0.024 15.6 1.6 1 23 245 268 245 268 0.95

4 11 0.034 2.3 9.3 3.3 1 21 274 294 274 296 0.95

5 11 0.00012 0.0081 17.0 2.7 1 23 302 324 302 324 0.99

6 11 8.7e-05 0.0059 17.5 5.4 1 23 330 352 330 352 0.98

7 11 0.0026 0.18 12.8 1.0 1 23 360 383 360 383 0.96

8 11 0.0097 0.65 11.0 4.1 2 23 390 411 389 411 0.97

9 11 0.00016 0.01 16.7 2.8 1 23 417 439 417 439 0.99

10 11 6.7e-06 0.00045 21.0 2.3 1 23 445 468 445 468 0.96

11 11 1.2e-05 0.0008 20.2 1.4 1 23 482 504 482 504 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00033	0.022	15.7	2.6	1	23	189	211	189	211	0.98
2	11	6.6e-05	0.0044	17.9	0.8	1	23	217	239	217	239	0.98
3	11	0.00035	0.024	15.6	1.6	1	23	245	268	245	268	0.95
4	11	0.034	2.3	9.3	3.3	1	21	274	294	274	296	0.95
5	11	0.00012	0.0081	17.0	2.7	1	23	302	324	302	324	0.99
6	11	8.7e-05	0.0059	17.5	5.4	1	23	330	352	330	352	0.98
7	11	0.0026	0.18	12.8	1.0	1	23	360	383	360	383	0.96
8	11	0.0097	0.65	11.0	4.1	2	23	390	411	389	411	0.97
9	11	0.00016	0.01	16.7	2.8	1	23	417	439	417	439	0.99
10	11	6.7e-06	0.00045	21.0	2.3	1	23	445	468	445	468	0.96
11	11	1.2e-05	0.0008	20.2	1.4	1	23	482	504	482	504	0.97

Sequence Information

Coding Sequence: ATGGCACCTCCTAAAAAGGAGGTGAAGATGGAGGCGGACAGTAAGGCTCTCCTCCAGACGTACCTGGAGAGCCTGAACAATCAACACAATGAAGAAGAGACAACTACTGTCATTGCAGTAAACGGCGAGGAAGATGCGGACTCGGGCGTGACCTATTTCGTGGATGAAGAGGGTCGTTACTACTACCAGCCAGCCGGCGACTCTCAGAACATCGTGTCTCTGCCCACCACCGTCAACAATGAAAGCGAGGCTATGGAAGAAGAGGAGAGTCAGATTCTGATGGAAGCCAATGAAGGGTTCCAGACGGTGACACTGGTGCCCTCCGAGGCCCCCAACGGAGAAGTGAGCTATGTCCTGGTCGTGCAGGAAGACAACAAACCTATTATCAAAGTGGATCAGATCGACGCCGAAAAGGCCGAAACCGAGGACGTGTACAACTTTGAGGACGACGTGGAGGGCGGAGAGGAAGAGTCAGACGACGACGACGACGATGATGATGATGATGGTGATGAGCACCTGATGCGGCGCAAGGGCCCTAAGAAGAACAAGGGGAGCCGGCCGCACTTCACGTGCTCTTTCTGTTCCTACACCAGCCCGCGCCGTTACCTGCTGCTACGCCACATGAAGTCCCACTCGGAAGATCGGCCGCACAAGTGCGCGGTGTGCGAGCGTGGCTTCAAGACGCTGGCCTCGCTGCAAAATCACGTCAACATGCACAATGGGGTGAAGCCGCACATCTGCAAATATTGCAGCTCGCCCTTCACCACCTCGGGCGAGCTGGTGCGCCACGTCCGCTACAAGCATACTCACGAGAAGCCGCACAAGTGCACCGAGTGCGACTACGCCTCCGTCGAGCTGTCCAAGTTGCGGCGGCACGTGCGCTGCCACACCGGCGAGCGGCCCTACCAGTGCCCGCACTGCACGTACGCGTCCCCCGACACGTTCAAGCTGAAGCGCCACCTCCGCACGCACACCGGCGAGAAGCCGTACAAGTGCGAACACTGCTCCATGTGCTTCACACAGAGCAACTCCCTCAAGGCGCACAAACTCATACACAACATCTCGGCCAAGCCTGTGTACGCGTGCGAGTTGTGCCCGACCAAGTGCGGTCGCAAGACCGACCTCCGCATCCATGTGCAGAAACTGCACACCAGCGACCAGCCCGTGCGATGCAAGCGCTGCGGAAAGACCTTCCCCGACCGCTACTCCTGCAAGATACACAACAAGACGCACGAGGGCGAGAAGTGCTACAAGTGCGACTACTGCCCGTACGCGTCCACCACGCTGCGCCATCTCAAGTCGCACCTGCTGAAGCATACCGACGAGAAGCCGTTTATGTGCGACCAGTGCGACCAATCCTTCCGGCAGAAGCAGCTGCTGCGCCGCCACCAGAACCTGTACCACAACCCGGAGTACAAGCCGAAGCCGCCGAAGGAGAAGACGCACGTGTGCCGCGAGTGCGACCGCCAGTTCGCGCACAAGGGCAACCTGATCCGCCACCTCGCCGTGCACGACCCCGACTCGGGGCACCGCGAGCGCGCGCTCGCCCTCAAGCTGGGCCGCCAGAAGAAGATCAAGTATGTCGACGCGGCGGATCCGGCCATCCAGAGGCAAGCGCAGTCGTCCGAGGAGTCGGAGGAGAGCGGCTCGGAGTCGGAGGGCGAGGACTCGATGCTGAAGCTGAAGGCGGGCGAGGGGGAGCTGCGTCGCGGCGAGCTGGTGACGGTGGGCGACGGCTCCGGCGAGCAGTACGTCGTGCTCGAGGTCATACAGCTGGACGACGGCAGCGAGCAGCATGTGGCCGTCGTCGCGCCCGGTGATGACTTCCCCATGGATAGCGTTGTTGAAGAAGGTGACGACGCGAATGACCCTATCGAGACGGAAGCGCGCGTGCGGAACGCCCACGCTGCGCAAAGCATCAAACTTGAGAAGGAAGTCGACACCTGCTTCGGCTTCGACGACACCGAAGAAGACGATAACGACGAGGTACAGCTGGGCTACAACGACAAGGTAGTGCTGCGCCTCGTCTAA
Protein Sequence: MAPPKKEVKMEADSKALLQTYLESLNNQHNEEETTTVIAVNGEEDADSGVTYFVDEEGRYYYQPAGDSQNIVSLPTTVNNESEAMEEEESQILMEANEGFQTVTLVPSEAPNGEVSYVLVVQEDNKPIIKVDQIDAEKAETEDVYNFEDDVEGGEEESDDDDDDDDDDGDEHLMRRKGPKKNKGSRPHFTCSFCSYTSPRRYLLLRHMKSHSEDRPHKCAVCERGFKTLASLQNHVNMHNGVKPHICKYCSSPFTTSGELVRHVRYKHTHEKPHKCTECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCEHCSMCFTQSNSLKAHKLIHNISAKPVYACELCPTKCGRKTDLRIHVQKLHTSDQPVRCKRCGKTFPDRYSCKIHNKTHEGEKCYKCDYCPYASTTLRHLKSHLLKHTDEKPFMCDQCDQSFRQKQLLRRHQNLYHNPEYKPKPPKEKTHVCRECDRQFAHKGNLIRHLAVHDPDSGHRERALALKLGRQKKIKYVDAADPAIQRQAQSSEESEESGSESEGEDSMLKLKAGEGELRRGELVTVGDGSGEQYVVLEVIQLDDGSEQHVAVVAPGDDFPMDSVVEEGDDANDPIETEARVRNAHAAQSIKLEKEVDTCFGFDDTEEDDNDEVQLGYNDKVVLRLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01543203;
90% Identity: iTF_01545974;
80% Identity: iTF_01543203;