Basic Information

Insect: Yponomeuta cagnagella
Gene Symbol: ZEB2
Assembly: GCA_947310995.1
Location: OX371296.1:1791585-1811533[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0012 0.082 13.9 0.2 1 23 252 276 252 276 0.97

2 14 5e-06 0.00036 21.4 2.2 1 23 283 305 283 305 0.98

3 14 0.13 9.6 7.4 0.1 1 23 309 332 309 332 0.91

4 14 0.035 2.5 9.3 1.2 1 21 345 365 345 366 0.95

5 14 5.2e-05 0.0037 18.2 3.1 1 23 370 392 370 392 0.99

6 14 0.0067 0.48 11.5 0.8 1 20 401 420 401 422 0.94

7 14 0.24 17 6.6 1.5 1 20 434 453 434 457 0.87

8 14 0.00058 0.041 14.9 2.5 1 23 463 486 463 486 0.95

9 14 7e-07 5e-05 24.1 3.8 3 23 499 519 498 519 0.98

10 14 0.0013 0.093 13.8 0.2 1 23 525 548 525 548 0.96

11 14 0.0017 0.12 13.4 2.7 1 23 563 586 563 586 0.94

12 14 0.00016 0.011 16.6 1.1 1 23 592 615 592 615 0.95

13 14 2.8e-05 0.002 19.0 4.6 1 23 623 645 623 645 0.98

14 14 0.04 2.9 9.1 0.4 2 23 653 675 652 675 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0012	0.082	13.9	0.2	1	23	252	276	252	276	0.97
2	14	5e-06	0.00036	21.4	2.2	1	23	283	305	283	305	0.98
3	14	0.13	9.6	7.4	0.1	1	23	309	332	309	332	0.91
4	14	0.035	2.5	9.3	1.2	1	21	345	365	345	366	0.95
5	14	5.2e-05	0.0037	18.2	3.1	1	23	370	392	370	392	0.99
6	14	0.0067	0.48	11.5	0.8	1	20	401	420	401	422	0.94
7	14	0.24	17	6.6	1.5	1	20	434	453	434	457	0.87
8	14	0.00058	0.041	14.9	2.5	1	23	463	486	463	486	0.95
9	14	7e-07	5e-05	24.1	3.8	3	23	499	519	498	519	0.98
10	14	0.0013	0.093	13.8	0.2	1	23	525	548	525	548	0.96
11	14	0.0017	0.12	13.4	2.7	1	23	563	586	563	586	0.94
12	14	0.00016	0.011	16.6	1.1	1	23	592	615	592	615	0.95
13	14	2.8e-05	0.002	19.0	4.6	1	23	623	645	623	645	0.98
14	14	0.04	2.9	9.1	0.4	2	23	653	675	652	675	0.93

Sequence Information

Coding Sequence: ATGAATGTGATTGCATGTTCTTTTTGTTTGTCGACGGATAGAAATCTGTTTATGGTCAACGAAAGACGTTTTCATTTAATTTATTCGTGGTTTGACATTGACGATGCCGAGTACATCAAGTACCTGCAATTGGAGGGCCTACTCCGGGCGTGCTGGTACTGCCAGGCCCGCCTCAAGAACTGCGCGAGCTTCGCGGTCAGTGCGCAACAGAGTGTGCACACTCTACGTCACTACTTGAGCACGCCTCACGAGCCCCCACCGGCGTCACAGAGCAGCTTAGCCATAACAGAGGTGGAGTTGGTGGATGTGGTGCCATCGGAGTCCGAGCCGTCAGTGGAGCCCCGGGGCGAAGCGCCGGGCGCGCCCCCGGCGGCGGGAAAGGCAGAGGACGTGAAGATCGAGTTTGAACTTGTGCAGCTGTCAAAAGAGAAGCCAGCCTTCAACGCTGTGAAGGTCGAGGACGACCTGCCAGGCGCTGACTACTTCGACATAGACTCGCCAGAGCCGAGCTTTGAGCTCCTCACTAAAGGGGATGGGGAGAAAAAGCAGGAAGAAGCTACTGGCTTGAACGAAGCAGAGGGCGTCAAAAACGAGGCACCAGCGATGAAGAAAAAGAAACTCAAGAAGGGGAGTGTAAAGTCTAAAGCAGCACCGGCGAAGGCGACGAAACTCCGTTGGACGGTCCAGTGGGCATCCAACGAGTCCGCGCTGGCTTGGTACTCGGCGGAGAGGGACGGCGAGCCTCCCGGCGAGTTCCCGTGCGCCCAGTGCGGCCGGAAGACCTTCGCCAGCGACGCTGAGCTGACAGAACATATGAAGACCAAACATGATGAGAGCGCCGGCAACTACCAATGCAACCTCTGCAAGTATCGCTTCGACACACAATCCACTCTTCAGCAGCACATCGAGAAGCACTATCTGGTGTACAAATGCCGCATCTGCACGTACGAGAGCCGTAGTTGGAAGCCAATGCAGGCTCACTGGGCCGAGGCGCATAAGAAGGCTGTTGAAAAGGCACCGAAACAGAGTTCCTATCAGTGTAAAAGGTGTAAGGATAGTTTTGCCACGTTTCCACTCCTGCGCAAGCACAGACTAAAGTGCTCGACGTACAAGTGCGGTCAGTGCGAGAAGACGTTCAAATACCACTCGTCGTTATACGAGCACGCTCGGATACATAAGGAGGGGGCACAGGACCAGATGTACTATTGTCAGGTGTGTGATACTCAGTTCAAGAGTGCGCGATGGTACAAACAGCACTTCAGCATCAGCTTAAAACATGTCTCTCGAGATGCCTTCAAACACGAGTGCCCGCACTGCCAGATGCGTTTCCACATCCCTCGTCGCCTGCGGGAACATGTCGGCGCTGTACACCTCAAGCACGGGATCTACGCTTGCAGTCTCTGCCCGAAGACTTACATGACCAAGCTGCACCTGAAGAAACATCGTGCCAAGCTGCACAACATTGGCGACGTAGTGGTCGCCCGCGACAAGATCTGCGACCACTGCGGGAAGGCTTTCACGTCCAACCACCTTCTGAACAATCACATGCGCTCTCACACCGGTGAGAAGCCGTACAAATGCCAGCTCTGCCCGGCCGCCTTCGCTCAGAACGGAACTCTCTACACGCATAACAAGAGTGTGCATCGGAAGAAGCTGAGTAAAGACGGACATACAGACTCGCCTGCTTACCAGTGCGAGGAATGCGGCAAGGAGTTCCCGACCAACTGCAAGCGGCAGGCCCACTACGAGTACTTTCATCTGAAACAGTCCAAGTTCACCTGCGAGGTCTGCAATAAGATCTTCATGTCCTCGACGTCGCTCAAGAACCACAATGCGACCCGGCACGGGATGCTCTCTAGCAAAAGTTTCAACTGCGACACTTGTGGGAAGAGGTTCAATACGTCCTCAGCGCGCTGTAACCACATGAAAACCCACCTGGCAGATGGCAGCGGACTGAAATGTCGTTCCTGTGACGCCGAGTTTAAAAACCCTGGCGCCCTCTATATGCATTTTAAACTCAAACACCTGAAGCTAAAACGGAGCGATAAAGTCAGTATCAAGAACCTGTGCAAGTCTGACAAGGAACTGATTGTGAACAGGGATCCGCAGTGA
Protein Sequence: MNVIACSFCLSTDRNLFMVNERRFHLIYSWFDIDDAEYIKYLQLEGLLRACWYCQARLKNCASFAVSAQQSVHTLRHYLSTPHEPPPASQSSLAITEVELVDVVPSESEPSVEPRGEAPGAPPAAGKAEDVKIEFELVQLSKEKPAFNAVKVEDDLPGADYFDIDSPEPSFELLTKGDGEKKQEEATGLNEAEGVKNEAPAMKKKKLKKGSVKSKAAPAKATKLRWTVQWASNESALAWYSAERDGEPPGEFPCAQCGRKTFASDAELTEHMKTKHDESAGNYQCNLCKYRFDTQSTLQQHIEKHYLVYKCRICTYESRSWKPMQAHWAEAHKKAVEKAPKQSSYQCKRCKDSFATFPLLRKHRLKCSTYKCGQCEKTFKYHSSLYEHARIHKEGAQDQMYYCQVCDTQFKSARWYKQHFSISLKHVSRDAFKHECPHCQMRFHIPRRLREHVGAVHLKHGIYACSLCPKTYMTKLHLKKHRAKLHNIGDVVVARDKICDHCGKAFTSNHLLNNHMRSHTGEKPYKCQLCPAAFAQNGTLYTHNKSVHRKKLSKDGHTDSPAYQCEECGKEFPTNCKRQAHYEYFHLKQSKFTCEVCNKIFMSSTSLKNHNATRHGMLSSKSFNCDTCGKRFNTSSARCNHMKTHLADGSGLKCRSCDAEFKNPGALYMHFKLKHLKLKRSDKVSIKNLCKSDKELIVNRDPQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01545090;
90% Identity: iTF_01545090;
80% Identity: -