Basic Information

Gene Symbol
-
Assembly
GCA_935412865.1
Location
CAKXYQ010000349.1:503785-507357[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.0024 0.19 12.7 0.7 1 23 250 273 250 273 0.94
2 18 2.3e-05 0.0018 19.1 2.6 1 23 278 300 278 300 0.99
3 18 8.4 6.5e+02 1.6 0.3 2 23 304 325 304 325 0.86
4 18 0.011 0.89 10.6 0.2 1 23 330 353 330 353 0.96
5 18 0.00063 0.049 14.5 0.5 2 23 414 436 413 436 0.96
6 18 0.00042 0.032 15.1 1.0 1 23 442 465 442 465 0.93
7 18 0.0012 0.094 13.7 0.4 3 21 470 488 468 489 0.94
8 18 0.0023 0.18 12.8 1.5 1 23 497 520 497 520 0.94
9 18 0.42 32 5.7 0.3 1 23 525 548 525 548 0.94
10 18 0.0046 0.36 11.8 0.1 2 23 561 582 560 582 0.95
11 18 0.0029 0.23 12.4 1.8 1 23 588 610 588 610 0.97
12 18 7.8 6e+02 1.7 0.2 2 10 616 624 615 631 0.86
13 18 0.0099 0.77 10.8 2.5 1 23 646 668 646 668 0.97
14 18 0.047 3.7 8.7 0.3 3 23 674 694 673 694 0.93
15 18 0.0089 0.69 10.9 1.7 2 23 712 734 711 734 0.94
16 18 0.00053 0.041 14.8 2.7 1 23 740 762 740 762 0.98
17 18 0.001 0.08 13.9 6.0 2 23 769 790 768 790 0.96
18 18 3e-05 0.0024 18.7 1.9 1 23 796 819 796 819 0.97

Sequence Information

Coding Sequence
ATGGCTGAATCAGAGACAAGTCACGTGGATTCTGCCAAACTAGATTGGATTAAACAGAAGCTACAAACTATATGGACATCGCCCAAGTTCTGCGGACTATGTCTGGAAAACCAGGGTAACTTCTGTTCGGTTGACATGGAACTTGTGATCAGCAAACAGACATTCTCTAAATGTTTGCAAGATATCATCAATTATGTTTTCAATGATGATATTGAAAACCTGATGTCCAGTCCTTATTTATGCGACACTTGCACAGAGAAAACAATACAGTCTTATCTCTTTATTCACAACACTAAACAACTGTCAAGGATCCTGAACAACTGTGTTGTTGACATTTATTCCAAAGTTATTGATGTGAACGAACAGCTCCAAGATAACATAAAATATGAGGCAGACAATGTCATGATAGTACTAGAAAATGACACTGAACTTTATAAAACTGTTATTGACATGAAATCTACAATTGAGATAGTGCCAACTCCAAAGCCTATAGCCATGAAGGAAGCAGTAGCTCCTAAAGTCGAACCAAATTTTATTCCTGTTGGTAAACTTCATAATGTACCTATTGTGATGCCTGAAAAGAAGGTAGAAAAACCTAAGGAAGTAATAACAAAGAATGAAGAAATCAAAGAAAACAAAGTTGTAAATCCTGATTGTACTCCAAATATTACTTTAAAAGAAGGCCACATAGTTATAAAACCTTTAATTTCCATAAGAAATTCAACACAAGTACCCCGATTCAACACTTATGAGTGCGCTAACTGTACAGAAATATTTACCACATACAGATCCCTAAAAGAACATGAAAAGGCTAAGCATAAAAAGGCTGTATTCCGCTGCAAGTTATGTGATAAGATTTATAACACACAGCAATATCTAAACATACATTATAAGACACATTCAAGAGCTAGATGCAAATTATGTCAACTTATACTTCCAGAGGAGGATTTAATGGACCATTTGAAGACAAATCATCAAAATTTTGTATATCCTTGCAATTTTTGCGATTTAGTATACTACTCAGAAGAATCTTTGGACACACATTTCAAAATAATCCATTTAGTGAATGACACAAAAGCCCAATTTCAATGTATCATGTGTCTCAGGAGTTTCTTGGAAGCTGAATTAAAGAAGCACAAATGTAAATTCTCTTGTTCAGAATGTTTTGTTATGCCGTGCATTCACTACAAGTATTTGAGATCGTATAGGGAACAAATTTTAAGCCATGCAAATAAAGTAAAATGCGAAGAATGTGATTACGTCACTCGGCGAAAGGAACATTTGATAGGACATGCAAACAGAGAACATTTGGACCATCACCCATTTACTTGTGCAGATTGTGGACAACAGTTTTACACTAAATTAAGTTTAAAGACCCACATAGTACAGTTCCATCAAGATCTCTTCTGTCAATACTGTGACTTTGGATTTAAAGATAACAACACTTTGGAAAATCATAGAAGAGCCTGCAAAAGTGTTATACGTGAATATGCCTGTAAGCAGTGTGAAGCGTCATTTGATCATCCTGATGAGTTGAGTCATCATGAGAATTTAAAACATAATGACGGAGTTTATGCTTGCCCCCTCTGTAAGGGCAGGTTCCTAACAAATATACAGTTGGAAGAGCACCATGCGAGAGTACATGGAGGCATACAGTGTAAGAAAAGGAGAAAACACATAGAATGTTCACTATGTGACATAATGTTCAAAAATATAAAAGAATTGGTCCAACATGAGCAGTTACACAATGCAGATGATGTTTATCCTTGTAAAGTGTGCTCCAAACAGTTTAAATCGTTAATGAAATTATATATTCATAGTCAAAGGCACTATACAAACAGAATAAAATGTTCTGGTTGTAATAAAAGGGTTGCAGAATCATTCTACTCGCAGCATGCCGTTAGATGTCCCTACAAACGAGATGTAGCTTTAAGCCATGTTTGTGAAGTTTGTGGAAAGTCTTACCATCTGGAATCTCTTCTCCGTTTCCACCAAAGAGTCCATATGAAAGCAGCGCCATGTCCTCAATGTAACAAGATTATTAAGCCTACAAGTCTGAAAAGACACATGGATCAAATGCATGCTGGTGCTCCTACGAATGATCAACTAAAGAAAAAAAGTGGACCAAACCTTGAATGTGAGATATGCGGTCATGTAGTCAGAAAAAAATGTGATTTAGAAGCTCATAATAACCGTTATCATCTGAAAATTAAACCATATGTGTGTCATATATGCAGTAAAGACTTCTGTGGCAAGGTTCGCTTGAAAGAGCATATTGCAACACACACTAGTGATAATAGCTGCTTTTGTTCTATCTGCGGAAAGAAATTTGCTAACCGTGTCTGTCTAAAAATGCATTTCAGAATGCATACAGGAGAAACTCCTTATACCTGTGATATTTGTGGACTAAAATTCAGGTCATCAAGTATGATGAAAACTCACAGACTTAAAAAACATTTGGAGAAAACCATTTGCTGTCCATTATGTGATAGTATGTTCTTCATGGTCAGAGATATGAGACATCACTTCAAGAAATCTCATTGGAAGTACAAAGACGGGAGACCTTTCAATCCTAGGGACGTTGAGGAGTTACCCCAGGAGTTATACTATCTTTTTGAAGATGGGAGACTGCCAAAGCTGACTGAAAATCCGTAG
Protein Sequence
MAESETSHVDSAKLDWIKQKLQTIWTSPKFCGLCLENQGNFCSVDMELVISKQTFSKCLQDIINYVFNDDIENLMSSPYLCDTCTEKTIQSYLFIHNTKQLSRILNNCVVDIYSKVIDVNEQLQDNIKYEADNVMIVLENDTELYKTVIDMKSTIEIVPTPKPIAMKEAVAPKVEPNFIPVGKLHNVPIVMPEKKVEKPKEVITKNEEIKENKVVNPDCTPNITLKEGHIVIKPLISIRNSTQVPRFNTYECANCTEIFTTYRSLKEHEKAKHKKAVFRCKLCDKIYNTQQYLNIHYKTHSRARCKLCQLILPEEDLMDHLKTNHQNFVYPCNFCDLVYYSEESLDTHFKIIHLVNDTKAQFQCIMCLRSFLEAELKKHKCKFSCSECFVMPCIHYKYLRSYREQILSHANKVKCEECDYVTRRKEHLIGHANREHLDHHPFTCADCGQQFYTKLSLKTHIVQFHQDLFCQYCDFGFKDNNTLENHRRACKSVIREYACKQCEASFDHPDELSHHENLKHNDGVYACPLCKGRFLTNIQLEEHHARVHGGIQCKKRRKHIECSLCDIMFKNIKELVQHEQLHNADDVYPCKVCSKQFKSLMKLYIHSQRHYTNRIKCSGCNKRVAESFYSQHAVRCPYKRDVALSHVCEVCGKSYHLESLLRFHQRVHMKAAPCPQCNKIIKPTSLKRHMDQMHAGAPTNDQLKKKSGPNLECEICGHVVRKKCDLEAHNNRYHLKIKPYVCHICSKDFCGKVRLKEHIATHTSDNSCFCSICGKKFANRVCLKMHFRMHTGETPYTCDICGLKFRSSSMMKTHRLKKHLEKTICCPLCDSMFFMVRDMRHHFKKSHWKYKDGRPFNPRDVEELPQELYYLFEDGRLPKLTENP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00050237;
90% Identity
-
80% Identity
-