Basic Information

Gene Symbol
-
Assembly
GCA_963678675.1
Location
OY783197.1:29064656-29069990[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.015 1.2 10.2 0.7 2 23 455 477 454 477 0.93
2 14 9.5 7.7e+02 1.4 2.2 2 23 560 582 559 582 0.95
3 14 0.00045 0.036 15.0 0.3 2 23 753 775 752 775 0.95
4 14 0.006 0.49 11.5 0.4 2 23 782 803 781 803 0.95
5 14 0.25 20 6.4 1.9 2 23 915 937 914 937 0.91
6 14 0.0053 0.43 11.6 4.3 1 23 1141 1164 1141 1164 0.94
7 14 1.9 1.5e+02 3.6 0.7 2 21 1234 1253 1233 1256 0.79
8 14 0.37 30 5.8 0.3 1 22 1263 1284 1263 1284 0.93
9 14 0.64 52 5.1 0.5 2 21 1290 1309 1289 1312 0.82
10 14 0.0031 0.25 12.4 0.9 1 23 1319 1342 1319 1342 0.98
11 14 0.037 3 9.0 2.9 2 23 1398 1420 1397 1420 0.96
12 14 0.27 22 6.2 0.9 3 23 1427 1446 1426 1447 0.93
13 14 0.26 21 6.3 1.3 2 23 1502 1524 1501 1524 0.93
14 14 0.7 56 5.0 0.1 3 23 1528 1549 1527 1549 0.90

Sequence Information

Coding Sequence
ATGGAATGTAATGTAcaaattgcaaataaaaattgGGACTCGTCAGAGTATATTAAAAAAAGGTATATCAATAAATTCGAACATTCATTGCATAAGCGAGACAATCTTACGGAATATCTCCTGATAAAACGTGCTAGGAAGCAAAAATTAAGTGTAAAGCGCGATATTAGAGAGGAGAATGAAATTGACGAGGAACTTAACGTCGATGACCCAAGAACTGGCGATGGTTTTAACGAAAAAACATCAACAACCGATAACTCCCACGTTCAAAATGTTACGAAAATTACCGAAACAATAGTATCTCCTCTTCGTCCGAAAAATGATGTTAACGACAAAGTCAAGATCACGGAGAAATTGAACGATGAAGGACAGCGGATAGAATGTAATGACGAAAGTGAAGATAACGGAGAAATTAATGTCACTGATTTGAAAACAAGCGACAACGACCTCGATGAAGAATCACCAGCGATCAATAACGCCGTCGCTGAGGATGTCAGTCCAGTTACGGAAACAATACGACCTTCTTCTAATCAAGGAGATGCCTTCAACGCTAAGACGGTAGTAATGAAAGAGTTGATCGTACCGTTGATAAAATTGGAGGGATCGTTCCTGAGGGAATTACTGAGTCACGGGACGCAGGGAGCGACAGATTCAAAATCGCCGGTACGAACTGACAACCAACAGGATAGCAATTGTAAACGAGACGAAAGTAACGCAAATCGGGCGAAAATGCTACAAAGTGATGTTTCCAGAGAACCAAAtcttgaaaatgaaaataattggGCTTCTACTAATTCGATACCAGAGCTAAGAACGCACGAAGGACTTGAAATGGAAACTCTAGAAGCAATTTCAAAATCTTCCGACGATCACGTAGATGCGGAAATAAAAGAAACACCTCCAAGAAACGACGAAAGTATTATTAAAACCGGTGAGTCAGAGGAAATGTTAACGGATCAGGATGTCATTACAAATACAAAGACTGTGAGAGAAAATGAAATGGAAACTAATGAGAGATCTTGCGCTGATCGCGTTATGTTCGACTCGAACACCGGAACTGTGCAAGAACAAGAACATGATAAAGAAAGTAGTAAAAAACCTGTTACGTTGATACATATTGTGAAAGACGAAATTTTGCATCAATTCATTAAAGACCCAAATATCAAGACCCAACGCCGAACGGATTCACATTCGAAGGGAGTGGAAGGCACGAATCCACCACAACTTTCAACGGAAGAAAACGCAGAGAAGGAAAAGCCCAAATGGTGTAAAACTTGCAACGCGGGCGTTTTTCGATTGATACATGAGCTTCGAGAATACCGGAAGTGGAATGATCGAGCCGAAGGACAAGGGGATCCTATTAAATGTCCTTACTGCTCTATGTATTTTGTCTCTCTGTATTACTTGTACTGGCATTTGGCCCATACTCATACGCGGTGTGAGTGTAAGCATCCTTCGAAAATAGACATTGATAACAAGAGGAAGAAAATTAAGGAAACCAAACGAGCAGAGCTCGATACCAATACGCTGAGCGAGGGCAAACGTCCTTCAGAAGTGCTTAAGGATGTTGAAAAGGAGGTACAAGACAGTGAGGAACTGCAGCAAACGGTACAAGCACATAAAGGAAGGAGGACACGGCAAACAGAGAAAACAGATTCGGATGACGCGAGAGTTGTCAAATGCCGTTACTGTTGTGAGAGATTTCCTACTATACaagcatttcgaatgcattccaGGGTGTCCCATGCCAAACCTATAAAGGCTAAAAGAAAAAGACGCAAGCTCAACAATCCGAAAAACACGTCAGTCGATTGTTTGAAATTCAATACGGACAAGTCTAAATTAAAGGAGGGTGAAGTGATGGACGATCTGATGAGAGAGCGAATCATTGACAATACGAGTAGCGAAGATGACTGGGAGATGATTGCAAGTGACGACTCGAGCAAGGCAAATCCAACAATAGATCATTCAAAAACGAATGACGACGAACCTGAAGccaaaattaaaaaactgaCTGACGAGCTGGAAAATTCTAGGAATAATATTAACGGTATAAATAATGAAAATCTGAAAACAAATGAAGATAAAAATTTGTACGCGATAAATGCACCATTGAAAAGTTCTAAAAAATTAGCGCGATTACCTAAGCAGAATCAAACCCCCGAAATTGCAAATGCGTCACAATGTATTGCTGATTCGACAAGCCCGGAAGTTAAAAATattaccggaagtaaaaatctTGTGGAAAGTGCACAACCGTGCTCGTTTTGTAAAGAAGTTTTTTCAACTAAAAGAGATTTAGCTATACATCAATCAGTCACTCATCCATTACGCTATCCGCTTATATGTGATGTTTGCTTTCGAGGTTTCAAACAGGAGCCTAAACTGACGAAGCACAAATTGGTGCATCAATATTCTAAAGGATCTACTAACAAAGATACCTCTACGTTATTTAAAAAACCAATTACTCCAGAAGTTATCACCGAGAAAATTGATTCGCGTCTCGACTTCTCGACTCTGGGGAACAGGAAGGAGTATGTCAATAAAAGAGCGAAAAATCACGTTATGGCATCAGCTGACAAGCCTAGCAATGAATTGCAAAAGACGACGATTGCAATTGCAACTGAAACCGCGCTTgagaaatgtaaaaataaacacGATTACGTTAAACCAAACACTAACGCATCTAGCAAAACATTACGCGAGACAATATCATTCAATGAAGAAAAGATGACAATAGTACAGTGCAAGAAATGTTACCGAAACTTCCTTTCCCAAAAGGCGCTGAACGAGCATATGTTCTTTTTCCATAGAAATTTTTTGAAGGAAGCGGTGGTTATCAATCAGCATAATGtcaaattgaaagaaaatagaCAAGAAATCAATCCCTCACGTAAAACCATGCCAAAAACCACGGTCAGCACGACGTCAATTCCTACAAAATGTTCACGTAGGAAATGGTTTGGCAAAactacggaaaaaaatgattcttccTCTGTGTCTAATTGGGTTCATTCGCCGTGGGAATGTAACACAATAAACACTTCTACGGAAGCAATACCACAGAAGAAAAGTGTAGAATCTACTGCAACGAATGGACAATGTACGCAAAAGACTTGTAAGATGACGATAAAAAATGCTTCTTCCTCCGATAAATCTGATAATACCGCTATAAACGAATCTACGCCGGAATGTAATAAAAGTACATTGTCGAAAAACACCGCCTCACAGGGAAATACAAAACATCATGTTAAGAATGATAATCGTAATAATATACAGTCAACCAAAAATGAAGAAATCAGCACCGAAGCAATGCTAAATGGGCATAACATGGAAACGTCGGAAATATCAGCGACAGAAGATATTAATGGATCTGCAAGGCTCGATAAGGGATACATATCAAACAATGATAGAATGATATTTTCGTGCAAACATTGCAAAAAGAAGTATTCTTCGCGAAAAGCTCTAGGCGAACATATGTTCTATTTACATGATGATTTCATAAGTGAAACTGAGGTCGTTACTGGTCAAGCCTCCAACTCGGCAGAAAACTCAAATTCTCCCAGTCAATTTAATGTATTTACGCCATCCACAAAAAAAATGTCAACATCTAAATATTACGAGCAGGAAGTTGAAACGTTAGCACTGCAACAGGAATCCAACGATTTGCAGCAAATAACACCGTGGAAGGGAGTATGGACCTGTAATTTGTGCGACGAAAGTTTCCCAGTAATGCGGAGATATATTCTACACAGATACCATTCCCACAACGATCAGTCAAGCGTTCACGTTTGCGACAATTGTGAAAAAGTCCTGACTTCCATTGAAATGGTTAACGCTCACTTATGTACGAAAGTCACCTCGTGGTCCTGTCGGCGCTGTACGAAGAGTTTCCCAACCGCCGTGGCATTAAGATTTCACAATAAGGAATTGCACATGGAAAAGCTGGGACTGTATACCTGTACTACGTGTGAAAGAGAATTTATGACAATAGGGATGTTGGATAGACACAAACGTACACTACATTCGTCTCTCGTTGATACGTCTATTTCTTCGCGGGAAAATGACTTGAACGCAAATCAGCCTAACTCCATAGAATCCAATAACGTTTCAGTATCCGAAATGAACGATATTGATAAATTGAGCCGCAAGGACGACGTTTATTCGACTGATGCTGACGATGAGGAATCTCAATGCAATCTATGTAAAGAGAATTTCTCCTCGTCGATTAATTTGAGATGTCATATAACGACGAGTCATCCGTCAGCTACTGAAATGTGTCAGTTTTGTCGTGAAATGTATAGATACGCAGATTTAGCGCGACACATCCTAATTCATCATTTCAGCTGGGATAATTCGATGAGAAACAAAGACGAATCTCAATCTGGAAAGGAAATGGAACTAACGCTACAGGATGATTATACGATTATTTCCAAACTTGGAGAGAAGCAAATTTTGTCTTTGTGTGAGTACAACGTTTTCGACGACGATCAGGATATCTGGGTCTGTCCTTTCTGCCCGaaattatttttgaacaatCGCCACTTCAAGATCCATCGTCTGTGGAGGCACGATAATTTTTGCGCCCTATGTAACGTCGCCTTTAAATCTAGTTATGAAGCGGCCAAACATAAAGGCGTCGCTCATGGATCGGTCGCAAGCTATTTATGGATGATTGAAGCACTTGTCGATATTATTGTGAAGTCTAAGAAGTATGGTGATAATGCGCAAAAGATCGTTTTTGACATTATTTCTCGCGAGGCTCAATGTTATCACAAAAGGGATAAGAAAGACGACGAGCTACTACAATGGAAAGACGATGAATTTCTCGGAGGTAAAACCAAAGAATTTAAAGAGACGAATTGTTTGAGCAATGCCGAACTGCTGGACGAGTCGAGCATTTATGAAAATGTTGCGAGAAATGAAGAGATTGACACAGATAATGTTCTCGGAGACGAAAAAGACAGCGAGGTCAATCTGGACGATCTAACGAAAGTTGAAGTAGGTACGGTTGGAGAACATCATGATTTGGATGGCGCAAAAGTACTCTTAGTTATCACAGAAGAAGATGTTGCTAATTCCCATGGCGACATTAACACCCTTGCTTCAAATATTTGTTCTACTTGCCCCACGATCCCCATAGAGGAGGTAAAGCAATTGTTGGTAGAATGTGCGGAAAATATGTCCATTgcggaaaatgtagaaaataATGATTATGAGAAAATGGACCAAGGAACGTAA
Protein Sequence
MECNVQIANKNWDSSEYIKKRYINKFEHSLHKRDNLTEYLLIKRARKQKLSVKRDIREENEIDEELNVDDPRTGDGFNEKTSTTDNSHVQNVTKITETIVSPLRPKNDVNDKVKITEKLNDEGQRIECNDESEDNGEINVTDLKTSDNDLDEESPAINNAVAEDVSPVTETIRPSSNQGDAFNAKTVVMKELIVPLIKLEGSFLRELLSHGTQGATDSKSPVRTDNQQDSNCKRDESNANRAKMLQSDVSREPNLENENNWASTNSIPELRTHEGLEMETLEAISKSSDDHVDAEIKETPPRNDESIIKTGESEEMLTDQDVITNTKTVRENEMETNERSCADRVMFDSNTGTVQEQEHDKESSKKPVTLIHIVKDEILHQFIKDPNIKTQRRTDSHSKGVEGTNPPQLSTEENAEKEKPKWCKTCNAGVFRLIHELREYRKWNDRAEGQGDPIKCPYCSMYFVSLYYLYWHLAHTHTRCECKHPSKIDIDNKRKKIKETKRAELDTNTLSEGKRPSEVLKDVEKEVQDSEELQQTVQAHKGRRTRQTEKTDSDDARVVKCRYCCERFPTIQAFRMHSRVSHAKPIKAKRKRRKLNNPKNTSVDCLKFNTDKSKLKEGEVMDDLMRERIIDNTSSEDDWEMIASDDSSKANPTIDHSKTNDDEPEAKIKKLTDELENSRNNINGINNENLKTNEDKNLYAINAPLKSSKKLARLPKQNQTPEIANASQCIADSTSPEVKNITGSKNLVESAQPCSFCKEVFSTKRDLAIHQSVTHPLRYPLICDVCFRGFKQEPKLTKHKLVHQYSKGSTNKDTSTLFKKPITPEVITEKIDSRLDFSTLGNRKEYVNKRAKNHVMASADKPSNELQKTTIAIATETALEKCKNKHDYVKPNTNASSKTLRETISFNEEKMTIVQCKKCYRNFLSQKALNEHMFFFHRNFLKEAVVINQHNVKLKENRQEINPSRKTMPKTTVSTTSIPTKCSRRKWFGKTTEKNDSSSVSNWVHSPWECNTINTSTEAIPQKKSVESTATNGQCTQKTCKMTIKNASSSDKSDNTAINESTPECNKSTLSKNTASQGNTKHHVKNDNRNNIQSTKNEEISTEAMLNGHNMETSEISATEDINGSARLDKGYISNNDRMIFSCKHCKKKYSSRKALGEHMFYLHDDFISETEVVTGQASNSAENSNSPSQFNVFTPSTKKMSTSKYYEQEVETLALQQESNDLQQITPWKGVWTCNLCDESFPVMRRYILHRYHSHNDQSSVHVCDNCEKVLTSIEMVNAHLCTKVTSWSCRRCTKSFPTAVALRFHNKELHMEKLGLYTCTTCEREFMTIGMLDRHKRTLHSSLVDTSISSRENDLNANQPNSIESNNVSVSEMNDIDKLSRKDDVYSTDADDEESQCNLCKENFSSSINLRCHITTSHPSATEMCQFCREMYRYADLARHILIHHFSWDNSMRNKDESQSGKEMELTLQDDYTIISKLGEKQILSLCEYNVFDDDQDIWVCPFCPKLFLNNRHFKIHRLWRHDNFCALCNVAFKSSYEAAKHKGVAHGSVASYLWMIEALVDIIVKSKKYGDNAQKIVFDIISREAQCYHKRDKKDDELLQWKDDEFLGGKTKEFKETNCLSNAELLDESSIYENVARNEEIDTDNVLGDEKDSEVNLDDLTKVEVGTVGEHHDLDGAKVLLVITEEDVANSHGDINTLASNICSTCPTIPIEEVKQLLVECAENMSIAENVENNDYEKMDQGT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-