Basic Information

Gene Symbol
-
Assembly
GCA_963678675.1
Location
OY783199.1:5857262-5860951[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.039 3.1 8.9 0.2 3 20 405 422 403 424 0.92
2 16 0.076 6.1 8.0 0.1 2 21 461 480 460 481 0.93
3 16 0.0018 0.15 13.1 0.1 2 23 524 546 524 546 0.94
4 16 8.6e-05 0.007 17.3 0.2 1 23 552 574 552 574 0.98
5 16 1.1e-05 0.0009 20.1 2.8 1 23 580 602 580 602 0.95
6 16 8.5e-05 0.0069 17.3 2.6 1 23 611 633 611 633 0.97
7 16 3e-05 0.0024 18.7 1.6 1 23 639 661 639 661 0.98
8 16 1.8e-06 0.00014 22.6 0.3 1 23 666 688 666 688 0.98
9 16 0.043 3.5 8.8 5.9 1 23 695 717 695 717 0.98
10 16 0.012 0.93 10.6 0.7 2 23 737 758 736 758 0.96
11 16 0.00083 0.067 14.2 0.2 2 23 766 788 765 788 0.93
12 16 0.0032 0.26 12.3 0.6 1 23 794 816 794 816 0.96
13 16 0.0066 0.54 11.3 3.7 1 23 822 844 822 844 0.98
14 16 2.9e-06 0.00024 21.9 1.1 1 23 850 872 850 872 0.97
15 16 1.1e-05 0.00086 20.1 2.1 1 23 878 900 878 900 0.97
16 16 0.00044 0.035 15.0 0.3 2 23 906 927 905 927 0.96

Sequence Information

Coding Sequence
atgaaagttgtGTGTGCTTCCACATCTTGTAAATATTCGTCAGAAAGAGAGGATTcttcgaatataattttcattagCTTTCCCAGCGATGATACTGCAAAAATTTGGGCTCATAATTGCGGAAGGCTGGACCTGCTGGTAAAACCTAACGAAGACCTCCACTCGAATTACTTTGTATGCTCTCATCATCTGGAGGatcaattttttattaataaatctGATCCGATCGTAATTGCACAAGGTGCTATTCCAACTCTATTCGAAATTGAAACCACTACAACTACGGAAACATATTCGACTATTATTCAAAAATCAGAATGTAAATCTAATGCTTTAAGAAATGATAATCAACCAAACAATTTGACGTATCATGTAACTGGTATCGAAGAATTGAACCATGCTATGGTCGAACGAGATTATCAGAATATCGATGCAAGTGGCGACTTGAATGgtgaaaagaataatacaatgttTGCTAAGGGGACTCCGATTGAGTCTATGGATAGTAATACTTTGACATACTGTATCTTAAATACCGAGATGGATGAGTACAATCACATCACGGTTGGATTTTCTAGTTTGTGTCGTTTGTGTGGAAATGACGCTTCGGATGGAATAGAAATATTTACTGGAAAGGGTGCCGAATTGAAATTAAAAGATAAGATAGGATTACACATGCCGATTTCTGTCAATGTAGACGATGTAATGCCACAGAGACTGTGCGCAGaatgttacaataaattggAAATCGCTCACGCCTTAGTTATGATGTGTCTTCAAACTGATATGAGATTTAGAAAATTCTTGAATATCGATGGAATACCACAATATGACAGTCGATTTGATGCTCTCGTTGAAGAGTGTTTCGCGGaaattaacagagattcttgtAATGAACAGGCTGCTCAGGATGAAGGCATTTCATTTGTTTCCAGCAAAGACGACGAAAAAAATCTTACGTACGCCGATAAGATAGAATATCAGCTGGGGAAATGCTTAGTATCAAAAGGCTTAGACCCAATAACGATATTGCCTCAATCGGACGACAAGACGACGAAGTTCGAAAGCGACAAGAAAAACGAGATACATTCTGCCCTCAATGATTTGTTTCAAGTACTCAAAGACGGTAAAAATAAGGATAATGAACAAGTTGCTCAATCTACATCCGAAAGGCATCAACTGACCGATAAAAAGGGGAGCGCTCCAATTATCTGCTTACTTTGTAAAGAAGAATTCAAAACACAAGAAATGTTCAAGAATCATAAAATTTTATGCGATGTATCGAAAAACTTAAAGTTAAAAACACAAAGAAAGAAAAGTGTTTACTCGGAGAAAAGGACAGCGGCAAACGAATCGAGTAATCGTCATTGCGGCACTAAAACTTGCAATCTTTGTAAAGCGGTGTTCGAAACGGAAACCGCATTTAATGATCATCAAATCTCACGTTGCGAATCATCCGAACAGTCGAGCAGTCAAATCTGCAACCAAACACTATTGAACGATAGCGAAGACGTAGATGTTCACGAAGACTTGCATGTACATATTAATGAATTAACCGGTACGAGTAGAAGGTGCGGTTATTGCGGAATCGTAACTTACTCGCGGAAGGAATTACAAAATCATATTTCCGAAATTCACGGAGGCCAGACACTCTTCAAATGCAGCATGTGCGATAAAGCTTACGAGAAATGGTCGAGTTTGGACGTTCACGAGGCTACTCACAGAATGGATAAGCCTTTCTTGTGCGATCTCTGCGGAAAGAGTTTTAAACACTCGAATAATTTACGGGGTCATAAGAGAATTCACTTGGACGAGTCCAAGAAGAAGCGACACGTTTGCGAGATATGTGGAAATGCATTTAGATCTAGGTTTCACTTGAGCGAACATATGAATCAACATAAAGGCAATAAACCCTATACGTGCGAACAATGTGGAAAAGCTTTTTACAAGAGAATACAATTACGGCAGCACAAACTTTCTCACGGATTGAATAAGTACGCTTGTCCTATTTGTGGTGTCACTTTCAATCGTCGAGGGAACATGAACACTCACCTCAAACGGCATAATAACGGGGAGGGAGTGTACACTTGCAGCGTGTGCGAATGCAGATGCAAATCGATGAGCGAGCTAAAAATGCACAGAAAAGAACATTCCGAACGCGATATAGTGGAGAGTGTCAAGAAGAAGTCAGCGGACAAGAGAGTTTGGCAATGCAAAATTTGCGCCAGGGTGTTCTCGAAACATGCAACTTGGTCGAGTCACGAACGAGCTCACGGCGGGGAGAAAATCAACGTGGAGTGTGACGAGTGCGGAAAGAAATTGGCTAGTAAGAGCTCCTTGGCATATCACAAGAAGGCGATGCACTCGACCGAGAGGCCGCACATGTGTCAATTTTGCGGAGAATCTTTCGTGTCCAAGGAAGCGCGATTGATACACGAGAGAATACACACCGGCGAAAGGCCTTACGCGTGTAAACAATGCAACATGCAGTACAGGTGCTCGAGCAACTTGAGCCAACATATGAAGATTCATTTGGAAACGCGACCTCACGTTTGTCAGTATTGCAATAAAGGTTTCACACGAAAGGGAGCTCTTACCGTCCACGAACGCATTCACACAGGCGTCAAACCGTTCGCCTGCTCTACTTGCGGGAGGACCTTCTCGCAGAAGAATGATATGCTGAAGCATACGAAGACTCATCGCTTCAAGTCAATGCAATGCGAGCAGTGCAACGAGGTGTTTTCGACGAAGAGGGGCATCTTAAAACACATGGCTCTGCATGAACAAGAAATTCCCGACCCGTCGGTTATCGAAGGATACGTAGAAGTCCCGCAAGAATTAGAACCGTACACGATAAATATCCCTTACCCTGACATAGACAATTCCAACGACATACAAGTCCTACAGAGCAAGTAG
Protein Sequence
MKVVCASTSCKYSSEREDSSNIIFISFPSDDTAKIWAHNCGRLDLLVKPNEDLHSNYFVCSHHLEDQFFINKSDPIVIAQGAIPTLFEIETTTTTETYSTIIQKSECKSNALRNDNQPNNLTYHVTGIEELNHAMVERDYQNIDASGDLNGEKNNTMFAKGTPIESMDSNTLTYCILNTEMDEYNHITVGFSSLCRLCGNDASDGIEIFTGKGAELKLKDKIGLHMPISVNVDDVMPQRLCAECYNKLEIAHALVMMCLQTDMRFRKFLNIDGIPQYDSRFDALVEECFAEINRDSCNEQAAQDEGISFVSSKDDEKNLTYADKIEYQLGKCLVSKGLDPITILPQSDDKTTKFESDKKNEIHSALNDLFQVLKDGKNKDNEQVAQSTSERHQLTDKKGSAPIICLLCKEEFKTQEMFKNHKILCDVSKNLKLKTQRKKSVYSEKRTAANESSNRHCGTKTCNLCKAVFETETAFNDHQISRCESSEQSSSQICNQTLLNDSEDVDVHEDLHVHINELTGTSRRCGYCGIVTYSRKELQNHISEIHGGQTLFKCSMCDKAYEKWSSLDVHEATHRMDKPFLCDLCGKSFKHSNNLRGHKRIHLDESKKKRHVCEICGNAFRSRFHLSEHMNQHKGNKPYTCEQCGKAFYKRIQLRQHKLSHGLNKYACPICGVTFNRRGNMNTHLKRHNNGEGVYTCSVCECRCKSMSELKMHRKEHSERDIVESVKKKSADKRVWQCKICARVFSKHATWSSHERAHGGEKINVECDECGKKLASKSSLAYHKKAMHSTERPHMCQFCGESFVSKEARLIHERIHTGERPYACKQCNMQYRCSSNLSQHMKIHLETRPHVCQYCNKGFTRKGALTVHERIHTGVKPFACSTCGRTFSQKNDMLKHTKTHRFKSMQCEQCNEVFSTKRGILKHMALHEQEIPDPSVIEGYVEVPQELEPYTINIPYPDIDNSNDIQVLQSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-