Basic Information

Insect: Xestobium rufovillosum
Gene Symbol: znf423
Assembly: GCA_963966045.2
Location: OZ014497.1:6613584-6622125[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0024 0.19 13.8 1.8 3 23 64 84 62 84 0.97

2 18 0.47 38 6.5 5.4 1 23 90 112 90 112 0.97

3 18 2.6e-05 0.0021 19.9 5.1 1 23 118 140 118 140 0.99

4 18 0.0021 0.17 14.0 0.2 1 23 146 168 146 168 0.98

5 18 0.00019 0.015 17.2 0.3 1 21 190 210 190 211 0.95

6 18 0.012 0.97 11.6 0.8 3 23 233 254 228 254 0.90

7 18 2.1e-05 0.0017 20.2 0.8 1 23 281 304 281 304 0.97

8 18 0.17 14 8.0 0.0 2 23 413 434 413 434 0.93

9 18 0.011 0.9 11.7 4.9 3 23 444 465 443 465 0.92

10 18 0.27 22 7.3 0.4 1 23 470 493 470 493 0.90

11 18 0.15 12 8.1 3.4 1 22 555 576 555 578 0.79

12 18 0.00053 0.042 15.8 2.7 2 23 656 677 655 677 0.97

13 18 0.15 12 8.1 0.5 1 23 686 708 686 708 0.90

14 18 0.042 3.4 9.8 0.1 1 23 836 858 836 858 0.96

15 18 0.015 1.2 11.3 0.2 2 23 867 888 866 888 0.95

16 18 0.019 1.5 11.0 0.1 1 23 896 918 896 918 0.96

17 18 0.27 21 7.3 2.6 1 23 925 947 925 947 0.96

18 18 1.2 93 5.3 2.5 3 23 960 980 958 980 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0024	0.19	13.8	1.8	3	23	64	84	62	84	0.97
2	18	0.47	38	6.5	5.4	1	23	90	112	90	112	0.97
3	18	2.6e-05	0.0021	19.9	5.1	1	23	118	140	118	140	0.99
4	18	0.0021	0.17	14.0	0.2	1	23	146	168	146	168	0.98
5	18	0.00019	0.015	17.2	0.3	1	21	190	210	190	211	0.95
6	18	0.012	0.97	11.6	0.8	3	23	233	254	228	254	0.90
7	18	2.1e-05	0.0017	20.2	0.8	1	23	281	304	281	304	0.97
8	18	0.17	14	8.0	0.0	2	23	413	434	413	434	0.93
9	18	0.011	0.9	11.7	4.9	3	23	444	465	443	465	0.92
10	18	0.27	22	7.3	0.4	1	23	470	493	470	493	0.90
11	18	0.15	12	8.1	3.4	1	22	555	576	555	578	0.79
12	18	0.00053	0.042	15.8	2.7	2	23	656	677	655	677	0.97
13	18	0.15	12	8.1	0.5	1	23	686	708	686	708	0.90
14	18	0.042	3.4	9.8	0.1	1	23	836	858	836	858	0.96
15	18	0.015	1.2	11.3	0.2	2	23	867	888	866	888	0.95
16	18	0.019	1.5	11.0	0.1	1	23	896	918	896	918	0.96
17	18	0.27	21	7.3	2.6	1	23	925	947	925	947	0.96
18	18	1.2	93	5.3	2.5	3	23	960	980	958	980	0.89

Sequence Information

Coding Sequence: ATGCTGTTTAAGGGAAATAGCAACAAGTTGCAATTATTGATAGAAAAAATTCAGTCCAGCAAAGAAAAACCAAGTATGAGAGAAACAGGTGATGCAGAAAATGGTTCACCAGCAGAAGTTAGTTCTCCTAATAGTCCGACTTCAGATGAAGAATGCACTGAAGGTGTTACTGAAAATACTCCTTATGGGTGCAGATATTGCCAAAGAGCTTTCGCGAGAAGTTGCATGCTAGCAAGGCACGAGCAGACACATACAGAGCAGCTCCAGTTTACTTGCTTGTATTGTCCGAGACTATTCAAACATAAAAGATCCCGAGACCGACACACGAAGCTTCATACCGgagataaaaaatacaaatgccAGCACTGCGAATCTGCATTCAGCAGAAGcgACCATCTCAAAATTCACATGAAATCCCACGATAGCCGTAAACCGTTTAAATGTGGTACCTGTAGTCGGGGTTACAACACCGCAGCAGCTCTCGCATCGCACCAGCAAAACCATTTTAAACAAGAAGTACGATCTGGTAGTCGTACCAGCGGGGGGAGCACCCCTAGTCCTAGTAATTTCCGCTGCGTCCACTGTCCTGAATCTTTCACAAAACCAGAACTTTTACAAAATCATCTCAATCTCGTGGAAGCTGAAGGTGGAAAACTTAATGGATGCAAAAATAACGTGGATCATTTGAAGGTTCATTGTATGTATTGCGGCAAAGATTTCTCGAGTGTTGAACAGCTTTATGCTCATGTAGATGCGAGCCATCGCGATGTAATCAACGGAGGCAGTCAGAGTGAAAACCAAGGGTCACCAAAACAAGAaattaaaactgaaaaaaacgcTTACAATTGCGATCATTGTACTAGAGAATTTGATAGTTGGTCTTCGCTTAATGAACATATAAGCACTGCTCATTTACGTCCAGTTTTGAATAACGTTTTGCTACAGTCTCCTTCCCAAAATTCTACTTTTTCTCCGTACCAATCCCGTCCTACTGATTTAAGTCATAGAAAGCGTAAAGATGATAGTGCCTGCTTCAAACCTTCGAAGAAAGTCAAGAATAACGATGCCAACGAGGGGTCATCCACCGGTAGTCCTTACGATTCTCAAGATAGGCCGTGCATTTGTTCTTGCTGTTACGCGCAAATGCcaaatttcaaaagttttttgGCCCACATGGAAAATCACGTTACTTTGAATCAGTCGAGTGTTGCTTCATCCAATCACGGATTTTTGGGATATTGTCCTATTTGTGGTGAACCTGGGAGAGATCCAGCTGAATTTGGTAACCACATTTTTGCTCACGCAATTACCAGTATACCTGGGAGATGTTGCCATTCTTGCAAGAAGTCCTTCGATAGGATGGATGATTTACAAAAACATTTGCTGGATATGCATGTTTTGTCTGTCTATAAATGTTCACTTTGCAATGATATTTTTGACTCGAAATCTGCAATACAGGCACATTTTTCAGCCAAACATGGGAACGAATGTAGCCACTTTCGATGTTATTTGTGTTCAGATCAAATTTTTCATGATCGACTGTCAGCTGAGTTGCACATTACTATGCAACACAGTCAACATATTACTACGGTTCCAACTTCCTTGCCCCCAGTGACTTACCAAGACGTGGAATCTGGAATATTTCAAGACTTCTATCAAGGATTCCAATGTCCATTCTGCCAAAAGTCATTTAAAGACGAACACCTACACTATCTACATGTCCTTAAGGAACATAACAGTACTCGCGAGAGAGATAAACTTTTGGCTGAAACACAGGGGCAAGGGGAAACCCCAACTTCCCCTAaattttttatgaaatcttcTACTCCAGAGAAACTAGACCAGAAACTCCCAGAAAACTTTGCTTGTGACTTATGCAACAGCTCAGAAATATCTTCAGAAGCAGAGCTTGTGGCACACAAAAAACTGCACCATTCAAAAACGAAAGCAGGCGCGGTAAGTCTCCAATGCGCATATTGCAACGAATATTGCAAATCAAGAACAGACCTAGAAAACCACATGAAAACGCATCAAGTTAGTTCTGGAAAAGGAAAATACAAATGTAACATCTGTGATGAAATATATTGCTCTCCCCTAATATTAGCAGATCACAAACTGAGGCATTGCAAAATATTATCAGGGAATACTTGTACGCAATGCAAGACGATTTTATTGAATGAACAAGCTTTTTACGCTCACCACATAGAGCACAGTCCAGGTAAAGCtaattcccaaatattcttacCCGTAAACTGTATAATTTGCTGCCAAACATTACAAACTGACGTGGAGCTTAGGTTACATTCGAAATTCCATTTGAGATGTTTAAACAAAAAGGAATTTGTTTGTAGAAGTTGTAAGCAAATTTACGACAATCAGACGGGACATTTAATGCAACAAGGAAAGAAATCATCGGAAACCTTGCCTGTTTCGATCTGCAAAACTTGCTCATCATCAAACGGAGTTGTTTATCAAAGTGAAGTTTCAGAAAACTCCAACAAACAGTACGCTTGTGTTCAATGTCCCCAGACTTTTGAAAGCGAGGAAGAAGTGCAAAATCACGCAACAATGCATGTGCTTAGTGACTGCTTAAGTTTAGAGTGCCGGCTTTGCAAGCAAATGTTTTCTTCGCCTCTAAAGCTCCAAATACATCTAATCGAACACAACTTTTATGGGATGAACCAATATAGTTGTTATGTTTGTTCTTCGGTTTTTACGGCCGCTAGTGGACTGCAAACCCATATCATCGGCCACGGCCTAAACAGCAGACCGTATGAATGCTCTCAGTGCCAAATGAAGTTCTTCTTTCGGACAGAACTGGACAACCACAAATTTGTACACACCTACGCCGAAAATGGTAGTTCGAAAACACAAATCTGCAAGTACTGCTCAGAGTCTTATTCGGACTCTTATTTGACGTACCATCTTAGTAAGTGTCACATGCGCTTGAATTTGACAGTACAAGAAGTTAAGTGTAAAGTAGAAGacgacaataaaataaaagaagaaaTTACTGGGGAGGATGTTCACTTGGATAATGGGGAAGAATCGAAGGAgcggttgtgtgaaacaaattGA
Protein Sequence: MLFKGNSNKLQLLIEKIQSSKEKPSMRETGDAENGSPAEVSSPNSPTSDEECTEGVTENTPYGCRYCQRAFARSCMLARHEQTHTEQLQFTCLYCPRLFKHKRSRDRHTKLHTGDKKYKCQHCESAFSRSDHLKIHMKSHDSRKPFKCGTCSRGYNTAAALASHQQNHFKQEVRSGSRTSGGSTPSPSNFRCVHCPESFTKPELLQNHLNLVEAEGGKLNGCKNNVDHLKVHCMYCGKDFSSVEQLYAHVDASHRDVINGGSQSENQGSPKQEIKTEKNAYNCDHCTREFDSWSSLNEHISTAHLRPVLNNVLLQSPSQNSTFSPYQSRPTDLSHRKRKDDSACFKPSKKVKNNDANEGSSTGSPYDSQDRPCICSCCYAQMPNFKSFLAHMENHVTLNQSSVASSNHGFLGYCPICGEPGRDPAEFGNHIFAHAITSIPGRCCHSCKKSFDRMDDLQKHLLDMHVLSVYKCSLCNDIFDSKSAIQAHFSAKHGNECSHFRCYLCSDQIFHDRLSAELHITMQHSQHITTVPTSLPPVTYQDVESGIFQDFYQGFQCPFCQKSFKDEHLHYLHVLKEHNSTRERDKLLAETQGQGETPTSPKFFMKSSTPEKLDQKLPENFACDLCNSSEISSEAELVAHKKLHHSKTKAGAVSLQCAYCNEYCKSRTDLENHMKTHQVSSGKGKYKCNICDEIYCSPLILADHKLRHCKILSGNTCTQCKTILLNEQAFYAHHIEHSPGKANSQIFLPVNCIICCQTLQTDVELRLHSKFHLRCLNKKEFVCRSCKQIYDNQTGHLMQQGKKSSETLPVSICKTCSSSNGVVYQSEVSENSNKQYACVQCPQTFESEEEVQNHATMHVLSDCLSLECRLCKQMFSSPLKLQIHLIEHNFYGMNQYSCYVCSSVFTAASGLQTHIIGHGLNSRPYECSQCQMKFFFRTELDNHKFVHTYAENGSSKTQICKYCSESYSDSYLTYHLSKCHMRLNLTVQEVKCKVEDDNKIKEEITGEDVHLDNGEESKERLCETN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -