Basic Information

Insect: Xestobium rufovillosum
Gene Symbol: ZFX
Assembly: GCA_963966045.2
Location: OZ014504.1:889315-894655[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.00015 0.012 17.5 0.7 1 23 209 232 209 232 0.97

2 20 1e-05 0.00081 21.2 1.5 1 23 238 260 238 260 0.99

3 20 1.8e-06 0.00014 23.6 0.7 1 23 266 288 266 288 0.99

4 20 0.001 0.084 14.9 2.2 1 23 294 316 294 316 0.98

5 20 0.0002 0.016 17.2 0.7 2 23 344 365 344 365 0.97

6 20 4.9e-05 0.0039 19.1 0.8 1 23 371 393 371 393 0.93

7 20 4.9e-06 0.0004 22.2 1.3 1 23 399 421 399 421 0.98

8 20 3.7e-06 0.0003 22.6 1.3 1 23 427 449 427 449 0.99

9 20 3.3e-06 0.00027 22.8 1.6 1 23 455 477 455 477 0.98

10 20 2.3 1.9e+02 4.4 1.9 2 19 779 796 778 802 0.91

11 20 0.011 0.87 11.7 1.3 1 23 808 831 808 831 0.92

12 20 3.6e-06 0.00029 22.7 1.2 1 23 837 859 837 859 0.99

13 20 0.00012 0.0096 17.9 2.4 1 23 865 887 865 887 0.98

14 20 1.2e-05 0.00097 21.0 0.7 1 23 893 915 893 915 0.98

15 20 6.7e-06 0.00054 21.8 0.4 2 23 943 964 942 964 0.97

16 20 0.00021 0.017 17.1 0.2 1 23 970 992 970 992 0.91

17 20 1.2e-05 0.00096 21.0 1.5 1 23 998 1020 998 1020 0.97

18 20 4.7e-06 0.00038 22.3 0.6 1 23 1026 1048 1026 1048 0.99

19 20 0.0026 0.21 13.7 1.3 1 23 1054 1076 1054 1076 0.96

20 20 0.00095 0.076 15.0 5.7 1 23 1082 1104 1082 1104 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.00015	0.012	17.5	0.7	1	23	209	232	209	232	0.97
2	20	1e-05	0.00081	21.2	1.5	1	23	238	260	238	260	0.99
3	20	1.8e-06	0.00014	23.6	0.7	1	23	266	288	266	288	0.99
4	20	0.001	0.084	14.9	2.2	1	23	294	316	294	316	0.98
5	20	0.0002	0.016	17.2	0.7	2	23	344	365	344	365	0.97
6	20	4.9e-05	0.0039	19.1	0.8	1	23	371	393	371	393	0.93
7	20	4.9e-06	0.0004	22.2	1.3	1	23	399	421	399	421	0.98
8	20	3.7e-06	0.0003	22.6	1.3	1	23	427	449	427	449	0.99
9	20	3.3e-06	0.00027	22.8	1.6	1	23	455	477	455	477	0.98
10	20	2.3	1.9e+02	4.4	1.9	2	19	779	796	778	802	0.91
11	20	0.011	0.87	11.7	1.3	1	23	808	831	808	831	0.92
12	20	3.6e-06	0.00029	22.7	1.2	1	23	837	859	837	859	0.99
13	20	0.00012	0.0096	17.9	2.4	1	23	865	887	865	887	0.98
14	20	1.2e-05	0.00097	21.0	0.7	1	23	893	915	893	915	0.98
15	20	6.7e-06	0.00054	21.8	0.4	2	23	943	964	942	964	0.97
16	20	0.00021	0.017	17.1	0.2	1	23	970	992	970	992	0.91
17	20	1.2e-05	0.00096	21.0	1.5	1	23	998	1020	998	1020	0.97
18	20	4.7e-06	0.00038	22.3	0.6	1	23	1026	1048	1026	1048	0.99
19	20	0.0026	0.21	13.7	1.3	1	23	1054	1076	1054	1076	0.96
20	20	0.00095	0.076	15.0	5.7	1	23	1082	1104	1082	1104	0.98

Sequence Information

Coding Sequence: ATGGAAAGTGTTGTCTTCTCTATTGAAGACGAAACAGCGAACGAAGAGAAATATGCCTGTGAAAGTGCAATTGCAGTACAAGAGTATCCTGAGTTGTGTAGGACCTGTTTGTCGAAAGAAGATATTAGACCCATTTTTCAGTTGAATTATAGAGGCGTAGAGTTCCATCAAATATTCGAAAAGTGTTCCGCAGTTAAAATTGGGCGAGATGATGATTTACCTCAAAATATTTGTCACAAATGTATAAACGATATAGTGTACGTTTATAAATTTATGCTCAAATGTCAGGAGTCGGATATTATCCTTCGAGCAGCAGTAAATAAAGTggataatgaaatttttgaaaatgtaaaggTTGAAGCAGATGACGATAAAGAATCAATTTCGCCAATCCAGTTATGGGAAAAAATTGATAGTCAATTGGACGAAAAGTCGGataacaataattttaatactGAAGATGTTGAGCCAAAGTGTGCGgtgaataaaaagaaaaaatcgtcgaatttttgCACTAAGAAAAAGGATGTTGCTGTAGCATGCAATAACTGCAATTATACAGTATGCAGTTACAAGAAACTCTCAATACATTGCAGACAAACTGGGCACTGTATGCCGAAGAGGTACAAATGTGAATATTGCGAAAAGTTTTTTATTTCTCCGAGTCGATTGTCTCTTCATGTAAAATCAGTTCATACTAAAGAAAAACCTTACGAATGCGAAATTTGTGGGTTTAAATTCAGCGCAAAATTCACGTTACGAAGACACATGATGAAGCACACGGGGGTGAAGCCTTATACGTGTGAAATTTGTGGAAAAGGTTTTCGTGAAACATCATATTTAGAAAACCATCTGCGAAAACACTCGGGAGAAAAGCCCTTCGTTTGTTCGTACTGCGGCGAAGGTTTCAGTAATCCAAGAAACCACAAACAGCACGAACGAAAACACGAAGTAGAAGACATTTTAAATAAGAAAGGCCGCACGAACCTTGCGGATGAAGctttgaaaaatccggatttgTTTGATAACGTTTGTACAAAATGCACGAAAGTTTTCGCCTCTAAGTATACTTTGGGGCAGCATTTATTAACGCATCAAGATAAACGGGCATATTTATGTAGCGAATGCGGGAAATGCTTCGTTACGAAAGGCGCCCTGCAAGTACATTCCACAGTTCATACCGGTGCTAAGCCGTACACCTGTGAAATCTGTCACAAATCGTTTTCTCAACTTGGAACATTAAATGTTCATCGACTGGTGCATACAGAAGAAAAATCTTACGagtgtaaaatttgtaaaagaGGTTTTAAATTAAATAGTCAACTGAGTCGGCACATGATAACGCATAGTGGGGAAAAACCTTTTTCTTGTACTTATTGCGACAAAAGTTTCGCTTTAAAATGTAATTTGATTGCTCATATACGTATCCATACAGGGGAAACCCCTTACGGTTGTGACGTCTGCGGTAAAAGTTGCCAGAATAAGAGTAGAAAAACTGGTAAAAGTGTAAAATATCATAGATTTCCTAAAGATAAAGAACTGTGTAAGGTTTGGGCTGAAAAGTGCAATTATATCGGACAAGTACATCCGATAAATTCCGTTGTTTGTTCCACACATTTTACTGCGGATGATTACGAACGAGATCTACAAGCGGAATTGATGAATTTGCCGTTGAAGCGTATATTAAAAAATGGAGCGGTACCGTCTCTCTTGTTGCCTCCACCTGACATTGTCCCGCAGCTAGAAACGGGTGCAATTGAAAATTGCAATCAACAGAGTCAAGTAAATGGTGAATTTCTTCCAAATAACGAAGCTAATTTAGAAACGGGCCACAAAGTGTTTATCGTAATAGGAAAACCGATGATGTTGAATAACTGCATTTCTGGCACCGTTTTGACAGAAGCACAATTTCCCCAACTCTGTCGATCGTGCTTATCGAGAAGCGATAACACTTCCATATTCAAATTGAATTTTGAAGGCCTGGATTTCCGGGATATATTCGAAACTTGCTGTGCTGTGAAGATTGCGAAAGATGATGGGTTGCCCCAAAATATTTGTCAAAAATGCATAAACGATATAGTGTACATATACAAATTTATGATCAAGTGTAAGGAATCGGATAGCGTTCTTAGAGCAATATTAGGCAAGGTGGATAATGTAATTGTTGAGAATATAAAAGCAGAACCAAATGACAATGAAGAATCAACTTCATCAGCCCCGTTAAGCGAAAATATTGACTATCAATCAGGAGAAAAGCCAGTTAATAATTGTAATACTGAAGACgttacaaaaaagaaaaaaaaattgaacaatCAGGAAAAGAACATTACTATAACATGCGCAAATTGCGACTATACGGTAGACACTTACAGGAAACTCACAAAACATTGCAGACAAACTGGGCATGTCGTGCCAAAGAGATACAAATGTGAACATTGCGAAAAATTCTTTATTTCACCGAGTAAAGTGGCTTTTCACATGAAAGcagttcatttaaaaaaaaaaccttATGAATGCGAAATTTGTGGGTTTAAATTTGCTGGTAAATTCACTTTACGAAGACACATGAAGACGCATACTGAGACAAAGCCTCATGTGTGTGAAATTTGCGGAATAGGTTTTTGTGAAACAAGTTCTTTAAAAAACCACCTGAGGAAACACTCCGGCGAGAAGCCGTTCATTTGCTCGCACTGCGGCAAAGGTTTCACTAATCCGGGAGTCCTCAAATGGCACGAACGAAAACACAAAGTTCAAGACATTTTGAATGAGAAAGTCGGCACGAGTCTTGTGGAAGAAGCTGCGAAACATCCAGATTTGTTCGACAAAGTTTGCACAATATGTGGGAAAGTTTTTTCGTCTAAATATGTTTTGAGACAGCATTTATTGATGCATCAAGATATTTACGCGTATTTGTGCAGCGAATGTGGGAAACGCTTTGCGACAAAAACTGGACTTGAAAATCATTCTGTGGTTCATACAGGTATTAAGCCTTATACTTGTGAAATCTGCCACAAATCGTTTGCCCAATTGTCAACATTGAACACTCATCGAGTAATACATAAAGAGGAAAAACCTTATAAATGTCAGATTTGCCCAAGAGATTTTAAATTAAAGGCCCAGTTGAATCGGCATATGATCATGCATAGTGGAAAGAAGGCACATGCCTGCAATTTTTGTGATAAAAAGTTTGCGTGGAGAGAAAACATGAAAGCACATTTGCGGGTACATACAGGAGAGGCCCCTTATGCTTGCGACGTCTGCGGTAAAAGATTCCATCATAGTAATAATAGAAAGAAGCATAGGAGAGTACATGATTCTGTAAAAGACAGTGTGAAATAA
Protein Sequence: MESVVFSIEDETANEEKYACESAIAVQEYPELCRTCLSKEDIRPIFQLNYRGVEFHQIFEKCSAVKIGRDDDLPQNICHKCINDIVYVYKFMLKCQESDIILRAAVNKVDNEIFENVKVEADDDKESISPIQLWEKIDSQLDEKSDNNNFNTEDVEPKCAVNKKKKSSNFCTKKKDVAVACNNCNYTVCSYKKLSIHCRQTGHCMPKRYKCEYCEKFFISPSRLSLHVKSVHTKEKPYECEICGFKFSAKFTLRRHMMKHTGVKPYTCEICGKGFRETSYLENHLRKHSGEKPFVCSYCGEGFSNPRNHKQHERKHEVEDILNKKGRTNLADEALKNPDLFDNVCTKCTKVFASKYTLGQHLLTHQDKRAYLCSECGKCFVTKGALQVHSTVHTGAKPYTCEICHKSFSQLGTLNVHRLVHTEEKSYECKICKRGFKLNSQLSRHMITHSGEKPFSCTYCDKSFALKCNLIAHIRIHTGETPYGCDVCGKSCQNKSRKTGKSVKYHRFPKDKELCKVWAEKCNYIGQVHPINSVVCSTHFTADDYERDLQAELMNLPLKRILKNGAVPSLLLPPPDIVPQLETGAIENCNQQSQVNGEFLPNNEANLETGHKVFIVIGKPMMLNNCISGTVLTEAQFPQLCRSCLSRSDNTSIFKLNFEGLDFRDIFETCCAVKIAKDDGLPQNICQKCINDIVYIYKFMIKCKESDSVLRAILGKVDNVIVENIKAEPNDNEESTSSAPLSENIDYQSGEKPVNNCNTEDVTKKKKKLNNQEKNITITCANCDYTVDTYRKLTKHCRQTGHVVPKRYKCEHCEKFFISPSKVAFHMKAVHLKKKPYECEICGFKFAGKFTLRRHMKTHTETKPHVCEICGIGFCETSSLKNHLRKHSGEKPFICSHCGKGFTNPGVLKWHERKHKVQDILNEKVGTSLVEEAAKHPDLFDKVCTICGKVFSSKYVLRQHLLMHQDIYAYLCSECGKRFATKTGLENHSVVHTGIKPYTCEICHKSFAQLSTLNTHRVIHKEEKPYKCQICPRDFKLKAQLNRHMIMHSGKKAHACNFCDKKFAWRENMKAHLRVHTGEAPYACDVCGKRFHHSNNRKKHRRVHDSVKDSVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01536399;
90% Identity: iTF_01536399;
80% Identity: iTF_01536399;