Basic Information

Gene Symbol
-
Assembly
GCA_963966045.2
Location
OZ014500.1:4893554-4914938[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 29 3.3 2.6e+02 3.9 2.4 2 19 240 257 239 260 0.95
2 29 0.00025 0.02 16.8 1.5 1 23 269 291 269 291 0.98
3 29 6.8e-05 0.0055 18.6 1.2 1 23 297 319 297 319 0.98
4 29 5.3e-06 0.00043 22.1 0.3 1 23 325 347 325 347 0.97
5 29 0.00031 0.025 16.5 0.3 1 23 402 424 402 424 0.97
6 29 1.7e-05 0.0014 20.5 0.1 1 23 430 452 430 452 0.96
7 29 1.6e-05 0.0013 20.6 1.9 1 23 458 480 458 480 0.98
8 29 5.5e-06 0.00044 22.1 3.3 1 23 486 508 486 508 0.98
9 29 2.2e-07 1.7e-05 26.5 0.5 1 23 514 536 514 536 0.99
10 29 0.12 9.4 8.5 0.6 1 14 542 555 542 557 0.92
11 29 0.0036 0.29 13.2 0.7 1 21 736 756 736 760 0.91
12 29 0.00017 0.013 17.4 3.4 1 23 766 787 766 787 0.99
13 29 3.4e-06 0.00027 22.7 0.5 1 23 793 815 793 815 0.98
14 29 0.00012 0.01 17.8 0.8 1 23 821 843 821 843 0.96
15 29 0.00034 0.027 16.4 4.3 1 23 857 879 857 879 0.97
16 29 2.5e-05 0.002 20.0 3.2 1 23 899 921 899 921 0.98
17 29 7.4e-06 0.0006 21.7 0.4 1 23 926 948 926 948 0.95
18 29 4.7e-05 0.0038 19.1 1.2 1 23 954 976 954 976 0.98
19 29 1.2e-06 9.8e-05 24.1 4.0 1 23 982 1004 982 1004 0.98
20 29 2.7e-06 0.00022 23.0 0.4 1 23 1010 1032 1010 1032 0.98
21 29 9.9e-06 0.0008 21.3 0.5 1 23 1038 1060 1038 1060 0.96
22 29 3.5 2.8e+02 3.8 0.2 7 23 1069 1085 1069 1085 0.95
23 29 0.0082 0.66 12.1 1.0 1 23 1099 1121 1099 1121 0.97
24 29 2.9e-05 0.0023 19.8 2.2 1 23 1140 1162 1140 1162 0.98
25 29 6.7e-06 0.00054 21.8 0.2 1 23 1167 1189 1167 1189 0.95
26 29 6.2e-05 0.005 18.8 2.6 1 23 1195 1217 1195 1217 0.97
27 29 1.3e-05 0.0011 20.9 6.2 1 23 1223 1245 1223 1245 0.98
28 29 0.00067 0.054 15.5 3.8 1 23 1251 1273 1251 1273 0.97
29 29 9.9e-06 0.0008 21.3 0.5 1 23 1279 1301 1279 1301 0.96

Sequence Information

Coding Sequence
ATGGATGATTCTACAGAGGATATAACAATAGTAGACTACAATGTTATTGATAACGTTACTCTTACGGTTGCCGATTTCCCGTACATTTGTCGGGTTTGTTTGTCGAAAGACAGTATAAATTCTATATTCGACTTAACGTATAATAGTTTCGAATTCCATAGGATATTCGAAGCATGTATCCCAGTTCAGATTGAGAGAGGGGACAAATTGCCTCAAGGCATTTGCTTGAAGTGCATGGATGACATGTTGAACTTCTACAAATTTATTCTTAAGTGTCAAGAATCTGACGTGATTTTAAAAGCTGTACTAGATAAAGAGGAGAATTCGAGCATGTGTTTGTTGAATGAAAATGATGTGAATCTTGAAACGATTGTAGTTGAGGAGGAATCAAATGATTCTCATGCTAATGTCAATACGGAAGAGGAATGCCTTATTTTGGTGGACTTAACGGACTCGGATGTGGATGGAGCGTTCCAAGAACCTGAAGATTACACCGAGGAAGTGCCTGCAAATTCTGAAGAACTTCTCGAGAATTCCGAAGAACTTCCCGAGATTTTTGAGGAACTTCCTGAGATGCTGGAAATTACGGATGTTATAAGTGAAACTATAGCAGAGATGAAGGAAAACAAGAAAAGTCAAATGAAGAAGAAAGCGAGACCTGAAAAGTTGAAAATTACAACAGAAAAAGTAAAAGAGAAAGTTGAACGTCCACCCGTTGAGTGTAACACATGCAACGCTCAGTTCGAGAGTACCAGGAATTTCTTTAAGCATTGTAAAGAAAGCGGCCATCCGTTCCCGAAAAACTATATGTGCGAAATTTGCGGGAAATCGTTCCAGTTCCGGCTACGATTGACGCAGCACTTGCGATCGCACACAAATGAGAAGCCCTTCATGTGTTCCGTTTGCGGAGCCAAGTTTACTCTGCACAGTAATTTGGGCAGACATATGAAAATTCACACTGGAGAGAAGCCCCATATTTGCGAAATTTGCGGAAAAGGTTTTATACAGGCGCCGACATTAACGGAGCACATGAGAAAACATACCGGCGAAAAGCCGTACGTTTGTTCGTGCGGTAAACGTGTGTCGTGCTCTTCGAATTATATAATGCACACACGCAGACACGAAATACAAGAAATTTTGGGGAAAAAAGATAAAATAGAGAAGTCGTCCGAAGAAGTGGTTAAGTACCCAGGTTTGTTCCAATATGTGTGTACCATTTGCGATAAAATACTGTTCTCTAAAGCCACGTTAAAAACTCATATGCTAGCTCACGAAGGTGTTAGACATTATCTGTGCAGTGAGTGTGGAAAAAGTTTCGTCACCAATGGAGGTCTGCAATCTCACGCTAAGATTCATACAGGAGAGAGACCCTACTCATGCGATGTATGCCACAGAACTTTTTCTCAAACTGGAAGCTTAAAAGTCCATCTATTGACCCATACGGGTGAAAGACCGTTTGTGTGTAAACTGTGCAGCAAGACGTTCATTCAAGGAAGTCACTTGAGAAGTCATATGCGGACGCATAGCGGTGAAAGGCCATACGTTTGTTCGTATTGCGGTAAAAGTTTTTCGTTAAATGGTACGCTTACGGTCCACATCCGAACTCATACCGGCGAAACTCCGTACGTCTGTGATGTATGCGGAAAAGGTTTCTACGACAGCAGTAAAAATGTAGTGGAAGATGGCCAGAGTCAAGGGAAAAGTAACATAATTGAAATTAATGCGGGTGAATTTGACAAAATTTGCAGAACATGTTTGTCCCATACAGATCTTCAAGCGATACAAGTTTTAAAATATGAAGACTTGTTTATTAGAGATATGTTGCATTCTTGCATATCTCTGGCGGTTAAAGAGTCAGACTGCTTGCCTCAACATATTTGTATGACCTGCATTAGAGAGCTGCTAAGAATGCACTTGTTTAAACAAAAATGCAGACAAAACGATGTGTTGTTACGAGCTGTTTTAAGTAAGAAAATTGAATTCGAATTGAAGGACGAAGTTGCCGCAAAAGAAGTTGATAAAGTAAATGATTCGAACGAGGAGGATTTTGATACGTCTTGTGGTCATAATGGCAATGTTTCCGATGATAGTGAGGAAGAGAAACCTGCAGTTAAAAATCGGAAACGAAAAAAAATTCTAACAGATGATGACGGCGTTAGACCATTCCgtagaaaaataaaaagaggtCATTCTCCCGGTGCACCTTACAAGTGTAAACAGTGCTCTGAAGTATTTGCGACGAAATCGATGTTTGTAGGACATCGGAAGGCTGCAAAACACTATGAAGTGCGAAATTACACCTGCAACACGTGTTCCAAGAAATTTACGAGTAGCAAGTTGCGGGAGCATTTGAGGACGCACACAAAGGAAAAACCGTTCGAGTGCAACGTTTGTTCGAAGGCGTTCAGTATGAGAGGAAATTTAAACAGGCACGTGATGACCCATACAGGAGAACGTCCgcatatttgtgaaatttgcgGGAAAGGTTTCATCCAGGCGAATTCGTTGCATGTGCACCGAGCGACCCACACGCTGTACGATCGTGTCTCTGAGACGTTTCCGGTGAAATTTGATTGTAAACATTGCGGGAGACAATTTAAACGTGTGGGTGCTTTCAATCGGCATACGAAAAGGCACATTGGGGAAAATgtcgagataaagaaaagtgATTATCGAGTAGACGAAGTTCGTAACCAtgtatgtgaaatatgtaagcGGTCGTATAAAACGAAAAGCTTGTTGAAAATGCATCAGCTGACCCACGGAGAGAAAACCTTTTTGTGTAGCGAGTGCGGGAAAGGTTTCGTGATGAAATCGTCGCTGCAGTCGCATCTTAGGGTGCACACAGGAGAGAAACCGTACACTTGCTCTGTTTGTAGGAAGTCGTTTTCACACATCGGCAGCTTTGAAGCTCACATGCTAATCCACACGGGGCAGAAGCCTTTCAATTGCAATATATGCACAAAATCGTTCACGCAAGCGTCTCATTTGACTTACCACTTGAGGACACATACCGGTGAAAGGCCTTATATTTGTTCTTTTTGCGGAAAGACTTTTGCGTTGAAAGGGAATCTGACCGTACACGTCAGGACGCACACAGGAGAGACACCGTATTTGTGTCCTGTGTGTGGCAAAGGGTTCTACGATTCGAGTAGTATGAAGAAGCATAGGAGAGGTCACGGGGAAATTACGTTACCGCCTCTAAATAAGTGTTTCATTCGAGTACGTTCATTACGAGTGCACCGAGGAACGCACACATCATGCGATGGTGTCACTGAAAAATTCAAAGCCCGATTTGATTGCGAACATTGCGGCAGACAGTTTAAACTAGCGGGTGCTTACGATCTGCATTTAAAAAGACATGCTGGTGAAATTTTCCAGGTGAAGAAGAACTATGATCCAATGGAAGTTCGAAACTACgtttgtgaaatatgtaaacatTCATTCGGGACAAAAAGTTCATTGAAAATTCATCGGTTAACGCATGGGGAGAAGACATTTTTGTGCAATGTATGCGGAAAAGGTTTTGTCACGAAAGCGTCTCTACAGTCTCACCTTAAAGTGCACACGGGAGAAAAGCCGCATACTTGCTCTGTTTGCAAGAAATCGTTTGCACACGCCAGTGGCTTACAAAATCACACGTTAGTCCACACAGGACAGAAACCTTTTAGTTGCAGTATCTGCAAGAAATCCTTTACGCAAAGTACTCATTTGAGGCGCCACTCGAAGACACATACTGGCGAAAGGCCTCACGTCTGTTGTTTTTGCGAGAAGACTTTTGCGTTGAAAGAGAATCTAACTGTTCATGTGAGAACTCACACAGGCGAGACGCCGTATTTATGCCCCGTGTGTGGCAAAGGCTTCTACGATTCGAGCAGTATGAAGAAGCATCGAAGAGGTCACGGAGAAATAACGTTACTGCCTGCAAAAGAGGAAGAATTGTTATGA
Protein Sequence
MDDSTEDITIVDYNVIDNVTLTVADFPYICRVCLSKDSINSIFDLTYNSFEFHRIFEACIPVQIERGDKLPQGICLKCMDDMLNFYKFILKCQESDVILKAVLDKEENSSMCLLNENDVNLETIVVEEESNDSHANVNTEEECLILVDLTDSDVDGAFQEPEDYTEEVPANSEELLENSEELPEIFEELPEMLEITDVISETIAEMKENKKSQMKKKARPEKLKITTEKVKEKVERPPVECNTCNAQFESTRNFFKHCKESGHPFPKNYMCEICGKSFQFRLRLTQHLRSHTNEKPFMCSVCGAKFTLHSNLGRHMKIHTGEKPHICEICGKGFIQAPTLTEHMRKHTGEKPYVCSCGKRVSCSSNYIMHTRRHEIQEILGKKDKIEKSSEEVVKYPGLFQYVCTICDKILFSKATLKTHMLAHEGVRHYLCSECGKSFVTNGGLQSHAKIHTGERPYSCDVCHRTFSQTGSLKVHLLTHTGERPFVCKLCSKTFIQGSHLRSHMRTHSGERPYVCSYCGKSFSLNGTLTVHIRTHTGETPYVCDVCGKGFYDSSKNVVEDGQSQGKSNIIEINAGEFDKICRTCLSHTDLQAIQVLKYEDLFIRDMLHSCISLAVKESDCLPQHICMTCIRELLRMHLFKQKCRQNDVLLRAVLSKKIEFELKDEVAAKEVDKVNDSNEEDFDTSCGHNGNVSDDSEEEKPAVKNRKRKKILTDDDGVRPFRRKIKRGHSPGAPYKCKQCSEVFATKSMFVGHRKAAKHYEVRNYTCNTCSKKFTSSKLREHLRTHTKEKPFECNVCSKAFSMRGNLNRHVMTHTGERPHICEICGKGFIQANSLHVHRATHTLYDRVSETFPVKFDCKHCGRQFKRVGAFNRHTKRHIGENVEIKKSDYRVDEVRNHVCEICKRSYKTKSLLKMHQLTHGEKTFLCSECGKGFVMKSSLQSHLRVHTGEKPYTCSVCRKSFSHIGSFEAHMLIHTGQKPFNCNICTKSFTQASHLTYHLRTHTGERPYICSFCGKTFALKGNLTVHVRTHTGETPYLCPVCGKGFYDSSSMKKHRRGHGEITLPPLNKCFIRVRSLRVHRGTHTSCDGVTEKFKARFDCEHCGRQFKLAGAYDLHLKRHAGEIFQVKKNYDPMEVRNYVCEICKHSFGTKSSLKIHRLTHGEKTFLCNVCGKGFVTKASLQSHLKVHTGEKPHTCSVCKKSFAHASGLQNHTLVHTGQKPFSCSICKKSFTQSTHLRRHSKTHTGERPHVCCFCEKTFALKENLTVHVRTHTGETPYLCPVCGKGFYDSSSMKKHRRGHGEITLLPAKEEELL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-