Basic Information

Insect: Xanthostigma xanthostigma
Gene Symbol: Zfx
Assembly: GCA_963575645.1
Location: OY754469.1:9748137-9751418[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.28 5.7 8.1 1.4 1 12 28 39 28 50 0.87

2 26 0.0038 0.078 14.0 4.5 1 23 54 77 54 77 0.97

3 26 1.5 31 5.8 4.6 2 23 86 104 86 104 0.95

4 26 0.017 0.34 12.0 2.1 1 23 110 132 110 132 0.96

5 26 0.65 13 6.9 0.0 2 23 138 160 137 160 0.88

6 26 0.67 14 6.9 0.2 2 23 170 190 170 190 0.96

7 26 0.00015 0.0031 18.4 2.4 1 23 193 215 193 215 0.98

8 26 0.00022 0.0045 17.9 0.9 2 23 222 243 221 243 0.96

9 26 3.1 63 4.8 0.6 1 8 249 256 249 259 0.92

10 26 2.8 57 5.0 0.5 1 11 304 314 304 325 0.90

11 26 0.016 0.34 12.0 2.0 1 23 330 353 330 353 0.97

12 26 0.16 3.2 8.9 1.6 1 23 359 378 359 378 0.93

13 26 0.00043 0.0089 17.0 0.9 1 21 384 404 384 407 0.90

14 26 0.00015 0.0031 18.4 0.3 1 23 412 435 412 435 0.93

15 26 9.2e-05 0.0019 19.1 0.9 1 23 468 490 468 490 0.98

16 26 0.59 12 7.1 1.9 2 23 497 518 496 518 0.96

17 26 4.5e-07 9.2e-06 26.4 3.9 1 23 524 546 524 546 0.99

18 26 2.6 54 5.1 0.6 1 13 626 638 626 646 0.92

19 26 2.7 55 5.0 5.3 3 23 654 674 652 674 0.94

20 26 3.5e-05 0.00072 20.4 1.0 1 23 705 728 705 728 0.96

21 26 0.0023 0.047 14.7 6.8 1 23 733 756 733 756 0.95

22 26 1.1 23 6.2 0.5 1 23 765 786 765 786 0.95

23 26 0.0017 0.035 15.1 0.2 1 23 789 811 789 811 0.98

24 26 2e-06 4.1e-05 24.3 1.5 1 23 817 839 817 839 0.98

25 26 2e-06 4e-05 24.3 1.4 1 23 845 867 845 867 0.98

26 26 0.008 0.16 13.0 2.8 1 23 873 895 873 895 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.28	5.7	8.1	1.4	1	12	28	39	28	50	0.87
2	26	0.0038	0.078	14.0	4.5	1	23	54	77	54	77	0.97
3	26	1.5	31	5.8	4.6	2	23	86	104	86	104	0.95
4	26	0.017	0.34	12.0	2.1	1	23	110	132	110	132	0.96
5	26	0.65	13	6.9	0.0	2	23	138	160	137	160	0.88
6	26	0.67	14	6.9	0.2	2	23	170	190	170	190	0.96
7	26	0.00015	0.0031	18.4	2.4	1	23	193	215	193	215	0.98
8	26	0.00022	0.0045	17.9	0.9	2	23	222	243	221	243	0.96
9	26	3.1	63	4.8	0.6	1	8	249	256	249	259	0.92
10	26	2.8	57	5.0	0.5	1	11	304	314	304	325	0.90
11	26	0.016	0.34	12.0	2.0	1	23	330	353	330	353	0.97
12	26	0.16	3.2	8.9	1.6	1	23	359	378	359	378	0.93
13	26	0.00043	0.0089	17.0	0.9	1	21	384	404	384	407	0.90
14	26	0.00015	0.0031	18.4	0.3	1	23	412	435	412	435	0.93
15	26	9.2e-05	0.0019	19.1	0.9	1	23	468	490	468	490	0.98
16	26	0.59	12	7.1	1.9	2	23	497	518	496	518	0.96
17	26	4.5e-07	9.2e-06	26.4	3.9	1	23	524	546	524	546	0.99
18	26	2.6	54	5.1	0.6	1	13	626	638	626	646	0.92
19	26	2.7	55	5.0	5.3	3	23	654	674	652	674	0.94
20	26	3.5e-05	0.00072	20.4	1.0	1	23	705	728	705	728	0.96
21	26	0.0023	0.047	14.7	6.8	1	23	733	756	733	756	0.95
22	26	1.1	23	6.2	0.5	1	23	765	786	765	786	0.95
23	26	0.0017	0.035	15.1	0.2	1	23	789	811	789	811	0.98
24	26	2e-06	4.1e-05	24.3	1.5	1	23	817	839	817	839	0.98
25	26	2e-06	4e-05	24.3	1.4	1	23	845	867	845	867	0.98
26	26	0.008	0.16	13.0	2.8	1	23	873	895	873	895	0.98

Sequence Information

Coding Sequence: ATGGCACCGATTGAGAAAAGTTTGAAAGCTCCTCGTTCTaagagtaaaataaaaaatttagtcgAAACCGCCGACGGCAAATATCGCTGCGAGTATTGCGGCGAAACTTTTGACACTTTCAAACGCTATCACTACTTGAAGCACGTGCAAAGCAAACCGTACAAGTGTAAAATCTGTGATAAAACGTATCATTTCAACTGGCAGTTGCGATATCATGCCAAACGCAGCCACGAGAAGAACAGTTCCGGACCGAACACGTGCGAAGTTTGCAACAAGTCCGTCAAACATTTGGCGCACCACATGCGCACACACACGCTCGAATACCGTTACAAATGCACGATGTGCGACAAGGGTTTCCATTGGCGCACGCAGCTGCAGCGGCACGAAGACGTGCACAATTCGATTCGTCTGATTTGCGGCGTGTGCGGCAAATCGTACGCCGGCGTCAACAATCTGCGCTTTCACGAGAAAGTCGCGCACGACCCGGCCTACTCGTTGCCGAAAGCGAAATGTGAAATTTGCGGCGACGAAGTGAACAAACGCGGCCTCGAGGTTCACATGAAACGACACGTCGGCTTCACTTGTCATCTTTGCGGCAAAGTTGTTACGTCGCAGTGCAGTCTCAACGCGCACTTGATGCTGCACAAAGGCGAGAAGCCGCTGAGCTGCGATGTGTGCGGCAAGAAGTTCTTGAAGAAGAGCAATCTGAACGTACATAAAAGAATACACGACGGCAGTAAGCCGTATCAGTGTAAGGAGTGCGGCAAGAACATTGAAGTGAAGATCGAAGACGAGGTTTTTGAAAATAACGAAATAAAAGCGAAGAAGCGCAAGCGCAAGACGAAAATAAAAAACGTGAAAGGTTTAAGATTTAAACTCAAAGCGTTGGTTCCTATGTCGGACGGCAAATATAAATGCGAAATTTGCAATGAAATATTCGACAAAATCAAGCGTTACCATTATCTCAAACACGAAATGTCGCGACCATTTAGCTGCGACTCTTGCGAGAAAACGTTTCAGTTGAATTGGCAGTTGAACAATCACAAAAAGAAAATGCACGTGAACCCGCAGGTTTACAAATGCGAcatctgtaacaaaactgtcaaGGACATGAAGTCGCATCAGAGAACGCACGTCGACGTGTTTCCTTTTAAATGCAACAGCTGCAACAAGGAGTTTCGCGTTAAGAGCCAGTTGAAAGTTCACAACGAGGCGGCGCACACCGACATCAGACACACGTGCGCCGTGTGCGGCAAGTCGTACACGAGCTTGGGCAATTTGCGCGATCACGAGAAAGCCGCGCACGATCCCTGTTACGATCCGCCGAAATTCACGTGCGAAATTTGCGGAAACGAAGTGCCGAACCGCTTCAAGGCCAAACACATGAAACGACACACGGGATTCACGTGTGACGTTTGCGGAAAATTCGTCACTTCTAAAAAGAGTCTACAGCTGCACCTGTTGCGGCACAAAGGTGAAAAGCCGCTGTCCTGTAACGTTTGCGGCAACAGTTTTCTGCAGCTGAACACGCTGAAGTGTCACATGCGAATACACGACGGCGTCAAGCCGTACAAGTGCAGGGAGTGCGGGAAATGTTTTAGGCAGAGCAGCAGTCTTAAAATACACGTCAGAATGCATACGGGAGAGAGACCGCCGTTTGTTTTGAAGACTGAGATAACAGATGCCGAAAACGCTTGCGCAGACCGCGGCAGCGATAATCTGAGCATACTGCGCAATCTTTTGTTATCGCCTGAAAGTGAGTTGAACGAAACTGTTAAAAAAGACAAGGCCGTTCGAAAAGAGAGGTCGTCGTCGAACGTCGAACTGGATTTGAAGGTTATGTCGAGATCGTTCGTTCCGGTGAAGAACGACAAATACAAGTGTCGTTTCTGCGACGAAATGTTCGACAGACCGCAGCCGGATCATTATTTGAAACACGAGGAGAGTCGTCCTTTCGGCTGCGACGTGTGCGGCAAAAAGTTTCTGTTGAGTTGTCATTTGAAAAGGCACAAGTATTACCACAAAACCAAACTGTCAAAGTGCGAAGTGTGCAACAAGACCGTCAAACACATAAAGAGTCACCGGATACTGCACAACGTGGAATCGTTTCGCTATAAATGCGAACTTTGCGGTAAAGAATTCCGTTTCAAATCGGAACTGAGCGCCCACAGCGAAACTTATCACAGCGACATAAAACACGCGTGCAACACTTGCGGCAAAATATTTCGACATCGGTGCAGTCTTAGAGCGCACGTGAAAAGGACGCACAATCCTTTTTATGTGGCGAAAACGTTCAAGTGCGAAGTCTGTTCTGAAAACGTGTCGACAAGCAACAGGGCGAAGCACATGGATAGACATCTGGGCTTCACTTGCGACGTTTGCGGCAAATGGGTCACCAGTTTGGGAAGCTTGAAGAAACACATGCTGCTGCACACGGGGGAGAAGCCGTTCAACTGTGAAACTTGCGGGAAGAGTTTCTCGAAACGAAGCACGCTCGTGCTCCACCTTCGAACGCATACGGGCGTCAAACCTTACGCGTGCAAGGAGTGCGATAAAAAGTTCACGCAAAGAACCAGTCTAGTTGTCCACATGAGATATCATAGCGGGGAGAGGCCCTACAAGTGCCATTTGTGTAGTAAAGCGTTTGTAAGCAAAACTATTTTAGATACTCATATAAAGAAGCATGGCTTTTAA
Protein Sequence: MAPIEKSLKAPRSKSKIKNLVETADGKYRCEYCGETFDTFKRYHYLKHVQSKPYKCKICDKTYHFNWQLRYHAKRSHEKNSSGPNTCEVCNKSVKHLAHHMRTHTLEYRYKCTMCDKGFHWRTQLQRHEDVHNSIRLICGVCGKSYAGVNNLRFHEKVAHDPAYSLPKAKCEICGDEVNKRGLEVHMKRHVGFTCHLCGKVVTSQCSLNAHLMLHKGEKPLSCDVCGKKFLKKSNLNVHKRIHDGSKPYQCKECGKNIEVKIEDEVFENNEIKAKKRKRKTKIKNVKGLRFKLKALVPMSDGKYKCEICNEIFDKIKRYHYLKHEMSRPFSCDSCEKTFQLNWQLNNHKKKMHVNPQVYKCDICNKTVKDMKSHQRTHVDVFPFKCNSCNKEFRVKSQLKVHNEAAHTDIRHTCAVCGKSYTSLGNLRDHEKAAHDPCYDPPKFTCEICGNEVPNRFKAKHMKRHTGFTCDVCGKFVTSKKSLQLHLLRHKGEKPLSCNVCGNSFLQLNTLKCHMRIHDGVKPYKCRECGKCFRQSSSLKIHVRMHTGERPPFVLKTEITDAENACADRGSDNLSILRNLLLSPESELNETVKKDKAVRKERSSSNVELDLKVMSRSFVPVKNDKYKCRFCDEMFDRPQPDHYLKHEESRPFGCDVCGKKFLLSCHLKRHKYYHKTKLSKCEVCNKTVKHIKSHRILHNVESFRYKCELCGKEFRFKSELSAHSETYHSDIKHACNTCGKIFRHRCSLRAHVKRTHNPFYVAKTFKCEVCSENVSTSNRAKHMDRHLGFTCDVCGKWVTSLGSLKKHMLLHTGEKPFNCETCGKSFSKRSTLVLHLRTHTGVKPYACKECDKKFTQRTSLVVHMRYHSGERPYKCHLCSKAFVSKTILDTHIKKHGF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -