Xxan022528.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Xanthostigma xanthostigma
Gene Symbol
THAP3
Assembly
GCA_963575645.1
Location
OY754475.1:16694597-16698794[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 6e-05 0.0012 19.7 4.1 1 22 469 490 469 490 0.96
2 17 0.024 0.5 11.4 0.4 2 23 498 519 497 519 0.97
3 17 1.6e-05 0.00032 21.5 4.6 1 23 525 547 525 547 0.99
4 17 8.2e-07 1.7e-05 25.5 4.3 1 23 553 575 553 575 0.99
5 17 4.2e-05 0.00086 20.1 5.7 1 23 581 603 581 603 0.99
6 17 2.4e-05 0.00049 20.9 3.0 1 23 609 631 609 631 0.98
7 17 0.0092 0.19 12.8 2.8 1 23 637 659 637 659 0.99
8 17 0.0038 0.078 14.0 0.1 5 23 666 684 664 684 0.95
9 17 0.0066 0.14 13.2 6.9 1 22 811 832 811 832 0.95
10 17 9.1e-05 0.0019 19.1 0.5 2 23 840 861 839 861 0.97
11 17 1.1e-06 2.3e-05 25.1 3.5 1 23 867 889 867 889 0.99
12 17 1.1e-05 0.00022 22.0 3.3 1 23 895 917 895 917 0.98
13 17 8.5e-05 0.0017 19.2 3.0 1 23 923 945 923 945 0.99
14 17 0.0036 0.073 14.1 3.0 1 23 951 973 951 973 0.99
15 17 7.9e-06 0.00016 22.4 0.7 1 23 979 1001 979 1001 0.99
16 17 2.8e-06 5.8e-05 23.8 2.9 1 23 1007 1029 1007 1029 0.99
17 17 9.2e-05 0.0019 19.1 2.8 1 23 1035 1057 1035 1057 0.96

Sequence Information

Coding Sequence
atggtGATTTATTGTGTTGCGTTTGGATGCCAGAATGAGCAAGATAAACGGAAAATATCTTTTCATGGTTTTCCATTTAAACGACCAGAAATCCTAAAGTTATGGATAAAGGCAGTTCGCAGGGATAATTGGGCCCCATCTAAAACCAGCAAACTTTGTGGAGAACATTTCCTTCCAACAGATTACATAGTCAAATCAGGGTACACCGCTAAACTATTAAAACTAGATGCTGTACCCAGTGTATTTTCATTTCCTAAGCATTTGTTACCAAAAACTGCTGAACCACGCAGGAAAATTAAAGAACTGGATGTCTCTGTGGATGTTCATAATGAGGATGTTcggcataatatattatctccTATGGACATCAATCTACCTTCTACATCAAGCACTCAAGTTGGAATGTTGATTGATCGTGAAACCCAAACAGTTTCATACACCAACAAAGATATACTATTACGAAGAAGAATTAAAACACTAACACAGAAAGTAAAGAGGAGGGATGTACAACTTTCCAACATGAAAGACGTAATTCAATCGATTTCAAAAGGCGGACATAGCAATGAAAATTTGGATGCGgttctaaaaaaacattttgaagGTAGTATAGCATTTCAcataatgaaagaaatatcaATAACTGGCCGTGGCCTTACtacaatgtgtcgattgtgtTTATCAAGAGGAGAAACGATGCTCGATGTGTTTCGATTTTCAACCAGATTTGAAGACAAAATCGTTGATGTGATAATGAAGTGTGCTCCTGTACAGGTACTGAGATACGATGAGATGCCGAAATTCGTATGTCGAAAATGTCTTACTAAACTAGAGGAAATGCGTCAGTTCCAAATGCAAATAATACAGTCTGACAAAACACTACGACGCTATTTACGGCAACTGCATGCTTCTGACAAAGAACCCCTGATCGAGGGTTCTATTCAAAGCTCTAATGATTCTTTAATCGCTAATACTAATGCAAACATCGAGTATGAATCTTCAGAACTCCATGACGTGTTTGACTTAAATGTCAACTGGAGAGAAAAAGAATGTGAGAACTTTAGTTCGGAAAGCAAAAATAACgatgaaatgtttttaaaatacgaaATAAAAGTAGAACAAACAGACAAGAATGCAATAACTCTACCAGATTGTGCTGATGATCCCTTAGAAATTTTGTCTAAAGGTGATGAGTTCACTGATATCAATATTGGCGAGAGGAAGATGGAAACAACTTTAAATTTTCAGTCAACATGCAAAAGCATTGAAATTAAACCCGAAATCAAAAACGAACCGACAGATGAAGAGTTGATCATGAACACAGAAAATGTTTCATCTAACAATTATTCTGACACTGAAATCAACAATGACAACATAAAGATTGATATTGACCTCATTTCGGGAAACTATTCTTGTGAGacttgtaataagtgtttcgttAATTCAGATGACCTTAAAAATCATATGTGTACTGTCACTGGAGAGAAAATGATTCAATGTGAGATTTGTAATAGGTTTATCTCAGGCTatgaaaatttcattaaacataaacgtatacataccgacgctaaaccatatcagtgtgacatgtgTGATAAGTGTTTCGCGCAAAAACCTCATTTAAAAGACCACAAACGTGTGCATACTGGGGAAAAACCATATAAAtgtaacgtttgtaataagtgcttCGCTCATGctgatagtttgaaaaaacacatACGTgtgcatacaggagagaaaccatataAATGTGACATGTGTATTAAGTCTTTCTCTCAGTCAAGCCATTTAAAGAAACATAAACGTACACATTCTGGTGAGAAGCCGCATCGGTGTGACGTTTGTGGTATGTGTTTCACACAGCCAGGAAATTTAGTTAGTCACAAACGTAGGCATACTGGAGACCGAAATTATCAATGCCACATTTGTATTAAAAGTTTCCTTAAGTCATCTAGTTGGAAAAGTCATATGCGTGTACATACTgaagagaaaccgtaccaatgtGATCAATCTTTCACACAAGCGTCTGATTTAAGTAAACACAAACTTTCCCATGCTgtagaaaaaacaaatgaatattcaGCTATCAATGTTGGCGAGTGTAAAGCGGAAGCACCTGCCATTTTTAAATTGGAAACCAAAAGTATTGaggaaatatatttaaaatccgaaatcaaagacACGCCGACATATGATGATGAATCAATAATTCAAACAGAATCAACTGTGGACACACAAAATACTACATTTAACGATTGCGGTAGTGAAATCAACAATGACGACATATATATTGATTTACACCATACTTCGGGGAACTCCGCGTGTGCTCGTTCTACCGATGTACAAAACATTATTGAGAATTGTGAAGACAAAGAAATTTCGGTAACTTTATCACAATCAGTAGGTACACGTAGGCATTCTGAAGATAAGCTGTATCCTTGTAAAATGTGTAGTAAGTGTTTCGTTAATTCAGATTGCTTGAAAAAGCACGTGTGTACTGTCACTGGAGAGATACTAATTCAATGTGAGATTTGTAATAGGTTTTTCTCCGgctatgaaaatttgattaaacataAACGCGTACATACTGACGctaaaccatatcagtgtgacatttgtgataAGTGTTTCGCGCAAAAAGCTCATTTAATCGTCCACAAACGTACGCATACTGGGGAAAAACCACATCAAtgtaacatttgtaataagtgcttCGCTCTTGCTGATACTTTGAAAAAACACATACGCgtgcatacaggagagaaaccatatcaatgtgacatttgtaagaagtgtttcgcTTTTGCTGATAGTTGGAAAAAACACAAACGTGTACATACAGAAAacaaaccatatcaatgtgataTTTGCATGAAGTGTTTCGTTGTAGATTCGTATTTGCAATCTCACAAACGTACACATTCTGGTGAGAAGCCGTatcggtgtgacgtttgtaataggGGTTTCACACAGCAAGGAAATTTAGTTATTCACAAACGTAGACATACTGGAGACCGACGTTATCAATGCCACATTTGTAATAAAAGCTTCATTGAGTCATATAGCTTGAAACTTCATATGCGTCTACATACTGGAGATAAACCGTACCAATGCGACGTTTGTGATAAATGTTTCACACATGCGGCTGGCTTAAGTAGACACAAAGTTTCCCATGCTGGAGAAAAACCAAATAAATATTCAGATATCGATGTTGGCGAGACTAAAGTGGAAGCACCTGCGAATTTTGAACCGGAAATCAAAAGTATTGATGAAACAAATTTGAAAGTCGAAATCAAAGACACGGCGATATATGATAATTAA
Protein Sequence
MVIYCVAFGCQNEQDKRKISFHGFPFKRPEILKLWIKAVRRDNWAPSKTSKLCGEHFLPTDYIVKSGYTAKLLKLDAVPSVFSFPKHLLPKTAEPRRKIKELDVSVDVHNEDVRHNILSPMDINLPSTSSTQVGMLIDRETQTVSYTNKDILLRRRIKTLTQKVKRRDVQLSNMKDVIQSISKGGHSNENLDAVLKKHFEGSIAFHIMKEISITGRGLTTMCRLCLSRGETMLDVFRFSTRFEDKIVDVIMKCAPVQVLRYDEMPKFVCRKCLTKLEEMRQFQMQIIQSDKTLRRYLRQLHASDKEPLIEGSIQSSNDSLIANTNANIEYESSELHDVFDLNVNWREKECENFSSESKNNDEMFLKYEIKVEQTDKNAITLPDCADDPLEILSKGDEFTDINIGERKMETTLNFQSTCKSIEIKPEIKNEPTDEELIMNTENVSSNNYSDTEINNDNIKIDIDLISGNYSCETCNKCFVNSDDLKNHMCTVTGEKMIQCEICNRFISGYENFIKHKRIHTDAKPYQCDMCDKCFAQKPHLKDHKRVHTGEKPYKCNVCNKCFAHADSLKKHIRVHTGEKPYKCDMCIKSFSQSSHLKKHKRTHSGEKPHRCDVCGMCFTQPGNLVSHKRRHTGDRNYQCHICIKSFLKSSSWKSHMRVHTEEKPYQCDQSFTQASDLSKHKLSHAVEKTNEYSAINVGECKAEAPAIFKLETKSIEEIYLKSEIKDTPTYDDESIIQTESTVDTQNTTFNDCGSEINNDDIYIDLHHTSGNSACARSTDVQNIIENCEDKEISVTLSQSVGTRRHSEDKLYPCKMCSKCFVNSDCLKKHVCTVTGEILIQCEICNRFFSGYENLIKHKRVHTDAKPYQCDICDKCFAQKAHLIVHKRTHTGEKPHQCNICNKCFALADTLKKHIRVHTGEKPYQCDICKKCFAFADSWKKHKRVHTENKPYQCDICMKCFVVDSYLQSHKRTHSGEKPYRCDVCNRGFTQQGNLVIHKRRHTGDRRYQCHICNKSFIESYSLKLHMRLHTGDKPYQCDVCDKCFTHAAGLSRHKVSHAGEKPNKYSDIDVGETKVEAPANFEPEIKSIDETNLKVEIKDTAIYDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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