Basic Information

Gene Symbol
PRDM13
Assembly
GCA_947086425.1
Location
OX352223.1:321781-325015[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.00039 0.022 15.4 4.8 1 23 79 102 79 102 0.97
2 23 0.036 2.1 9.2 1.0 1 19 174 192 174 197 0.95
3 23 0.00023 0.013 16.1 0.8 1 23 202 225 202 225 0.94
4 23 3e-05 0.0017 18.9 0.1 1 23 230 253 230 253 0.94
5 23 0.031 1.8 9.4 2.3 3 23 260 281 258 281 0.94
6 23 0.00025 0.014 16.0 2.9 1 23 285 308 285 308 0.97
7 23 0.21 12 6.8 0.5 2 23 315 336 314 336 0.96
8 23 0.0092 0.52 11.1 1.2 1 17 342 358 342 359 0.93
9 23 0.048 2.7 8.8 2.7 3 23 398 418 396 418 0.95
10 23 4.8 2.7e+02 2.5 0.0 3 23 444 465 442 465 0.84
11 23 0.0083 0.47 11.2 1.5 1 23 484 506 484 506 0.97
12 23 0.034 1.9 9.3 7.7 1 23 511 533 511 534 0.95
13 23 0.085 4.9 8.0 4.7 1 23 539 562 539 562 0.94
14 23 0.012 0.7 10.7 1.1 2 23 565 587 564 587 0.94
15 23 8.7 5e+02 1.7 0.2 2 20 594 612 593 614 0.90
16 23 0.042 2.4 9.0 1.5 1 23 668 691 668 691 0.97
17 23 0.003 0.17 12.6 0.5 2 23 766 788 765 788 0.95
18 23 3.2e-05 0.0018 18.8 0.6 3 23 795 816 793 816 0.95
19 23 0.00011 0.0064 17.1 0.7 2 23 821 843 820 843 0.96
20 23 0.12 7 7.5 0.2 1 23 848 871 848 871 0.96
21 23 0.0043 0.24 12.1 6.8 1 23 875 898 875 898 0.97
22 23 0.03 1.7 9.5 2.2 3 23 906 926 905 926 0.96
23 23 3.8e-06 0.00021 21.7 1.3 1 23 932 954 932 954 0.99

Sequence Information

Coding Sequence
ATGAAAGAAGAACACGAAATAGACAACGGTGGAAAGTGTGGTTTCTGTTGCAAACAATTTCACACGAAAAATAGTTTCTTAGATCACGCAACTAGATGTAAAGCTTTACCGAAGAAAGAGGTGATAGTCGTTGATAAGGTTGATAAGAACAAAATTGTACGAGATCTCAGAACCGGTATTGCGTATATCATTAACATGACCAACGCAATGCCTTTTAAGTTCTTCCAAAGCAAGTTTAGGTGCTTTTACTGCCCTAAAGATTTCACGACCTGTAATGACCTCAAACAACACACAACAACCGAACATCCTATATGCGAGACAACGTTTCACTCGATGAAACTTCGAGGCAGGTCTGATGGTATTAAAATTAAAGTTGACACATCTTCCATGTACTGCAAAATATGCTTCGAAAAGCTCGCAGATTTCATAACAGCTGTCAATCATTTAAAAGTTGAACACAAAGCTGTCGTCAACAAATACGTAGACATGTTTAGACCTTTTAATTTAGTTCATGATAAGTTTGTGTGCTCGTTCTGTGATACAGAGTTTCGATATTTCAGTTTGCTATTGCAGCATGACAATGCGACTCACTCGGATAGTCAATACATTTGCACGTTTTGCGGCAAAGCCTTCCCATCCTACCCTAATCTACGCGGTCATATCTCTCATTACCATTCCAGTGGTAGATTCAAGTGCAGTGAATGCGATCTAAGCTTTCCAACAAACGATGCCTTAGCGATACACATGGGCAATACACACGGGAGTAAAGTTATTAATTGTAAACAGTGTTCGGAGAAGTTTGTCTCTCGATATCATAAAATGAGACACGTTATAAAAGTGCATGACGGTGGCCACAAATGCTCGTATTGTGGTATGGCCTTCATCAAGTACTCGTTTATGACGAACCATATACGGCGATTGCACTTTAAAGAGAAGAATGTCCAGTGCGCGCTTTGTACCGAACAATTCTTTGATACGAATCGTCTGAAGTTGCATATGGTGAGGCATGTGGGCGAGAGGTCGTTTCGCTGTGACTACTGTGGAAAGCGTTTCTTGAGGAAGAAGAATCTTAGGGATGAAACGCCCGCCCTCCTGTCTGGCCGAAAAACGTCCCTGCGACGGAGGAAAAGCTTGAAAACATTATTCGAAAACACAACTATTTTCCCCTTCAAATTTCTAGAGACCCATCTTTGCTTCTACTGTAGCGCTTCTTTCGGCGATTACGTAGAATTCAGAAAGCATACAAAGTCTCACTCCAGATGTACTCAGGAGTTGAAAGAATTAAAAGAAAGTTCGGAAAATATTAAGGTTGATGTATCGGAAATCGCATGCGAGCGTTGCGAACAAGAATTCAAAACCTTAGAAGTGATTGTTGAACATTTGATAAACGAACACGGTTTATTTTATGACAAGGATGTTAACAACATCGTAGAGTACAGATTGATCGATTTCCGCTGTACACAATGTGACGCGCACTTCGAAACATTCAGAGATTTGGATGTTCACATCAGCAATCATCGCCAAAATGGTTTCATTTGTCATCACTGCGAACGTATGTTCATCAAAAAGAGTGATATTTCGTATCATATGTTTAAACACCATCATTTTGGTGGGTTCACTTGTAAACAATGCGGTGTTGAATGTAGAAGTCGATTAAAATTGCGGAAACATACAGAACATGCACATATGACGCGATGCCACGTTTGTGGCGATGTATTTGTGAACTTGAATAAACTGATCAAACACTTCAAGCTGGAACATCCGAGTGACAATAATAAAACCTGCGGCTACTGCTTAATAGAGTTCCAAACTATGCTCGGTTTGAAACAGCACTTGACGAAATGCAAACTAAGATTGCCTACGCTCAAGGAAAACGTAACTATAATTGGCAGCAAAAACGCTAGCACATCAAGAACGCACGAACAAATCGTCCGTATCCGTGAGAATATACTGTGCGTTCTAAACATGTCCACCGCAGTGCCCTTTCGATTTCGAGTCAAATTCTCCTGTTTCTACTGCTCTCAGAAGTACGATGATTACGAAGTTCTCAAACTACATACACGTTCAGAGCATCCCATTTGCGATATTAAGAGTAAATGCATAAAGACTTGTAAAGGAAAACGTACGTTTGTAAGGGTCGATATAGCAGATCTTGCTTGCAAACTGTGCTCTGCTCCTATGCCCGATTTGGACAACTTTATCGAGCACGCGATCTCAAACCATAATGCGGATTATGATAGGTCCGTCAGCATCGAGACTTGCTTTGAGCCGTACCGCCTCATAAAAGACAATATCCAATGCCTGGAATGTCCAAAAGTCTTCAGATACCTCAACACAATGCTGAGGCATTTCAACTCAGATCACAGCAATAATAATGTGATCTGTGATTACTGCGGACGCGGCTTCCGCACTACAACCAATCTAAAGATGCATCTGCAGAACACACACACCGGAACATCAGAATGCAAGATTTGCAACGCTAAATTCAAAAACCGCTCGGTTCTAGTTCGCCACATGGCTAAAAGCCACAACGAACTGACTTTCAAATGCCCCAACTGTTTAGAATTGTTCGCGTCTGCGTACAAACGACAGATTCATCTCATCAAAGTCCACGGCATCGGCCATAAATGCCAGTATTGTGGCAAAATGTTTACAAAACACTCGTTCATGGACTCTCACGTTAGACGAACACATTTGAAGGAGAAGAATGTTGCTTGCTCGATTTGCAACGATAAGTTCTTTGATAAGCATTTGCTTAAGATGCACATGGTTAAGCACGATGGGGAGAGGAAGTTTAAGTGTGAGTTGTGCGGTAAAGCGTTTTTGAGGCAAAAGAATTTGCGCACTCATATGGACACCCATAAGAAATACGGGTTTGTGCAGTGA
Protein Sequence
MKEEHEIDNGGKCGFCCKQFHTKNSFLDHATRCKALPKKEVIVVDKVDKNKIVRDLRTGIAYIINMTNAMPFKFFQSKFRCFYCPKDFTTCNDLKQHTTTEHPICETTFHSMKLRGRSDGIKIKVDTSSMYCKICFEKLADFITAVNHLKVEHKAVVNKYVDMFRPFNLVHDKFVCSFCDTEFRYFSLLLQHDNATHSDSQYICTFCGKAFPSYPNLRGHISHYHSSGRFKCSECDLSFPTNDALAIHMGNTHGSKVINCKQCSEKFVSRYHKMRHVIKVHDGGHKCSYCGMAFIKYSFMTNHIRRLHFKEKNVQCALCTEQFFDTNRLKLHMVRHVGERSFRCDYCGKRFLRKKNLRDETPALLSGRKTSLRRRKSLKTLFENTTIFPFKFLETHLCFYCSASFGDYVEFRKHTKSHSRCTQELKELKESSENIKVDVSEIACERCEQEFKTLEVIVEHLINEHGLFYDKDVNNIVEYRLIDFRCTQCDAHFETFRDLDVHISNHRQNGFICHHCERMFIKKSDISYHMFKHHHFGGFTCKQCGVECRSRLKLRKHTEHAHMTRCHVCGDVFVNLNKLIKHFKLEHPSDNNKTCGYCLIEFQTMLGLKQHLTKCKLRLPTLKENVTIIGSKNASTSRTHEQIVRIRENILCVLNMSTAVPFRFRVKFSCFYCSQKYDDYEVLKLHTRSEHPICDIKSKCIKTCKGKRTFVRVDIADLACKLCSAPMPDLDNFIEHAISNHNADYDRSVSIETCFEPYRLIKDNIQCLECPKVFRYLNTMLRHFNSDHSNNNVICDYCGRGFRTTTNLKMHLQNTHTGTSECKICNAKFKNRSVLVRHMAKSHNELTFKCPNCLELFASAYKRQIHLIKVHGIGHKCQYCGKMFTKHSFMDSHVRRTHLKEKNVACSICNDKFFDKHLLKMHMVKHDGERKFKCELCGKAFLRQKNLRTHMDTHKKYGFVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00267417;
90% Identity
-
80% Identity
-