Basic Information

Insect: Wyeomyia smithii
Gene Symbol: ZFY
Assembly: GCA_029784165.1
Location: CM056646.1:13478532-13481758[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.55 60 6.1 0.5 2 21 192 211 192 214 0.88

2 20 0.29 31 7.0 1.5 1 20 232 251 232 253 0.95

3 20 5.2 5.7e+02 3.0 0.2 2 23 260 282 259 282 0.91

4 20 0.22 24 7.3 1.8 1 23 333 356 333 356 0.93

5 20 0.0089 0.97 11.7 0.2 1 21 369 389 369 390 0.95

6 20 9.8 1.1e+03 2.1 1.2 2 23 397 418 396 419 0.91

7 20 0.83 90 5.5 2.0 2 23 526 547 526 547 0.94

8 20 3.7 4e+02 3.5 0.2 1 11 564 574 564 585 0.86

9 20 0.036 3.9 9.8 0.5 1 21 592 612 592 613 0.96

10 20 0.12 13 8.1 1.1 2 23 641 663 640 663 0.96

11 20 0.0064 0.7 12.2 2.9 1 22 676 697 676 697 0.94

12 20 0.7 77 5.7 1.9 1 23 752 776 752 776 0.93

13 20 2.4 2.6e+02 4.0 1.8 2 20 796 814 795 816 0.91

14 20 1.9 2.1e+02 4.4 0.1 1 23 823 845 823 845 0.85

15 20 0.0094 1 11.6 2.2 1 21 851 871 851 873 0.94

16 20 0.00028 0.031 16.4 0.9 1 23 878 901 878 901 0.95

17 20 0.18 20 7.6 2.3 1 23 906 928 906 928 0.97

18 20 4.5 4.9e+02 3.2 0.3 1 23 934 959 934 959 0.87

19 20 0.0004 0.044 15.9 3.1 1 23 965 987 965 987 0.98

20 20 0.0027 0.29 13.3 0.9 1 19 993 1011 993 1013 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.55	60	6.1	0.5	2	21	192	211	192	214	0.88
2	20	0.29	31	7.0	1.5	1	20	232	251	232	253	0.95
3	20	5.2	5.7e+02	3.0	0.2	2	23	260	282	259	282	0.91
4	20	0.22	24	7.3	1.8	1	23	333	356	333	356	0.93
5	20	0.0089	0.97	11.7	0.2	1	21	369	389	369	390	0.95
6	20	9.8	1.1e+03	2.1	1.2	2	23	397	418	396	419	0.91
7	20	0.83	90	5.5	2.0	2	23	526	547	526	547	0.94
8	20	3.7	4e+02	3.5	0.2	1	11	564	574	564	585	0.86
9	20	0.036	3.9	9.8	0.5	1	21	592	612	592	613	0.96
10	20	0.12	13	8.1	1.1	2	23	641	663	640	663	0.96
11	20	0.0064	0.7	12.2	2.9	1	22	676	697	676	697	0.94
12	20	0.7	77	5.7	1.9	1	23	752	776	752	776	0.93
13	20	2.4	2.6e+02	4.0	1.8	2	20	796	814	795	816	0.91
14	20	1.9	2.1e+02	4.4	0.1	1	23	823	845	823	845	0.85
15	20	0.0094	1	11.6	2.2	1	21	851	871	851	873	0.94
16	20	0.00028	0.031	16.4	0.9	1	23	878	901	878	901	0.95
17	20	0.18	20	7.6	2.3	1	23	906	928	906	928	0.97
18	20	4.5	4.9e+02	3.2	0.3	1	23	934	959	934	959	0.87
19	20	0.0004	0.044	15.9	3.1	1	23	965	987	965	987	0.98
20	20	0.0027	0.29	13.3	0.9	1	19	993	1011	993	1013	0.95

Sequence Information

Coding Sequence: ATGATCAGAACAGAGCAACATCTCCCGCGACTACCAGCGACCTTTTGTCGACCCAGGCTATGTCGGATATGCTGCGCTCCAGATAACGACGATCTAATTTCCGTGCAATTGATACAAGACGGAGTCAGTATAGCACAGATGCTTCAAGAGCTAACAGAAATCGAAgTCATGGCCGATAAGAATCTACCGCAAAATGTGTGTTTGAAATGTCTTGATCGTCTTAAAAATGCCTATCACCTGCGCCGCCAATGCATTGATTCAGATCGAATACTGAGAAGAGAACATTACCCGGAATCATTTGACAAGCTACAACCTATGGTAAAATTAGAAATCGAAACATTGCACGATGTAGATAATGTAAACGAAGATGATTCGATTGCTTGTGACGAAAATGAAGTAAACTCGAACGAAGAAATAAAACTCATTACATCGAATCAGGAATTGATAGCGGTTTTGACAGAtcaggagaaaagcaaaaacagACCCGTGTCGGTGTACTTGAGCCATGATGAAGCCGAATACGAAATTTTACAGCAAAGTGAACACTACGAGCACATAAGTCTTTTCGTGGCACAATGTTGTGGTTGCTCAGAAAGTTTAAGCGATAAAAATCAATTACTGCTTCACGGCGAGGCAGTACATCAAACTGATAAACAAGTGCTGAACGAATCAATCAAAAAAACCGGAACGCAATATGTGTGTCAGATTTGTTTTCACCAGTTTCCCGAGGAATCAGATTTTTCCAAGCATCGCATTCACATCGATGCACGTCAGTTGCGCTGTCGAGAATGTGGTTTGCTGTTAGATGATCTAGATCATATGTTAGAACATCTTTCACAAGTTCACTCGGTTGAGGTTGATAACCATAGCGAGAGGGACAGTGATGAAGGTTGCAATACTGATGTTGCTGCGCTTTTAACGTTGGCTTCGTTTGATTCAAACCAATACAAATTAGTTCCTACCGGGGAGGACTTTGACACAGTCGAGTTTACTTGCTTCAGATGCTGTGGATGTGAAAACGTCTTTAAAGTACGTGAACAGTTCGAATTACACTCGAAGGAAGTGCATAGCCCAGAAAGGATAGAATACGACGAAGAAATGCCATACGAATGTAGCATTTGTTATCAACGTTTTGCGAAAAAAGCTTCATTGGCATACCATAGAAACGGCTCCAGCAAGCGGCAAGTAGTTTGTCGAATTTGTGAAGGTTTGTTTAAAGGGGAAAGATCATATCGTAGGCATTTCCTGCAACATCATAGTATGGTTGAAGGAAATGAATTAAAAATGGATGTGAAGTCCCAGCAGTTGTCTAGCgtcaaacaagaaaatgatgAATGTAGTAAACTAGAGGACCAAAGTGAATGCGAAAGTATGCGAGAAGTTGAATTCATAGAAGACATTTTTGAGGATGAGGAATTGAATTCTGAGGATGACGAACTGGAAACAAGTAAACCAAGGCGAATAAATAAATACTTGCCAACAAGACAACGCAAGGAAATGGGAAAAGTGCCGGGAAATTTACTTCGCATCATTGAAGCATTGGACGGATACAATATTGTCGAAATAATGAAAGAACGATGCTGTCGTTGTTTGGAATTTTTCGACACACTTGATGAGTTGAATCAACATACTGAGGAGCATCGGCAGGAATCGCAGCTAGAAAACGAAACCTCGGATAAACCAATCAAATATCAGTGTGAGTTTTGTTTGAAGACGTTTGATATTGCTCTAGTCTATGTTGTACATAAAAGAATACGGGAACAAAAACAGTTCTACCAATGTAAGTTATGCGATTTCGTGATCGACTCCGAATCACGTCTCAAAAATCATATGCTGCACAACGAGCAACAtgccaaatttttcaatgtAATTCGTGAGGATGTTAGTGATCGATACGATGCAGTGCAACTCCCAGGAGTTCGCTGTTGTGGTTGCGGTgactattttaaaaatgatgaGAGTCTGACAGAACATTCTAGAACTGTTCATCCGAGGGATCATCGCAAAGATGGCCTAAAACGAGGACATGTCTGTACCGTCTGCGATAAACGTTGCTACAACAAATCCGAGGTGGAAAGCCACCAAAAGAAAAATGGTTCTACGATTCGTTACTATTGCAAACTATGTGAGTTTGAAACGGCTAGTGAAGCCCGCATGTTGAAACATCTGTACAGTTCGATACACAATCAATCGTTGCCAACCATTGAAGTAAAAAATGTAGAAGTTGGTTTCAGGAAAGCCGGAACTCTGCGCTACTGCTGTTTTGAGGGTTGTAATGTAACTTTTTGTGAGATAGGTAAACTGCAGGAACACGTCAACAGTATccataaaattgaaaaagaatCGAACATGTCTACACCACGGCTCGATATGGCTTCTAAATGGCAATGCGACTGTTGTTACCGCTTTTTTCGAACGGTGGCGTTGCTCAAACAGCATCAGTTCAGTCAACGCGAGACCAAAAGCTACGTTTGCTCAATTTGTGGGGCGGCGAAACTTAACAAAACAGCTTTAACAGCGCACGAAATGAGGCATACCGGCGAAAGACCTTTTGCCTGTACTGTATGTGATAAGcGCTTCGCTTCTCAGACAATACTTACTTCTCACATGAAGTGCCATGTTCCAAAGCAGTACGAATGTATCGAATGTGGTGAGAAATTCGCACGAGGAGAAAATCTCAAACGGCACATTCGCCACCGACATTCGGAGGCTACCTACTGCTGCAGTTATTGTCCGCGAAAGTTAAAAACACGGGAGGCGCAGGTTCTCCATGAGAGGTCCCACACTGGTGAAAAACCATTTGCGTGTCGCACCGAAGGTTGTGAAAAGCGGTACGCTAGTATAACTGACCGGAGACGTCACGAAATGGCCAGTCACACCGGAGAGCGTCCGCACAAATGTTCCTACTGTGTGGCATCATTTGTACGGAAACGTCAACTAACCATTCATGAACGGAAGCACACCGGCGAGCGACCGTTCGTCTGTAATCGCTGTGGGAAAGCTTTCATCGATGCCCCGTTTCTCAAGAAGCATTCCTGCTGA
Protein Sequence: MIRTEQHLPRLPATFCRPRLCRICCAPDNDDLISVQLIQDGVSIAQMLQELTEIEVMADKNLPQNVCLKCLDRLKNAYHLRRQCIDSDRILRREHYPESFDKLQPMVKLEIETLHDVDNVNEDDSIACDENEVNSNEEIKLITSNQELIAVLTDQEKSKNRPVSVYLSHDEAEYEILQQSEHYEHISLFVAQCCGCSESLSDKNQLLLHGEAVHQTDKQVLNESIKKTGTQYVCQICFHQFPEESDFSKHRIHIDARQLRCRECGLLLDDLDHMLEHLSQVHSVEVDNHSERDSDEGCNTDVAALLTLASFDSNQYKLVPTGEDFDTVEFTCFRCCGCENVFKVREQFELHSKEVHSPERIEYDEEMPYECSICYQRFAKKASLAYHRNGSSKRQVVCRICEGLFKGERSYRRHFLQHHSMVEGNELKMDVKSQQLSSVKQENDECSKLEDQSECESMREVEFIEDIFEDEELNSEDDELETSKPRRINKYLPTRQRKEMGKVPGNLLRIIEALDGYNIVEIMKERCCRCLEFFDTLDELNQHTEEHRQESQLENETSDKPIKYQCEFCLKTFDIALVYVVHKRIREQKQFYQCKLCDFVIDSESRLKNHMLHNEQHAKFFNVIREDVSDRYDAVQLPGVRCCGCGDYFKNDESLTEHSRTVHPRDHRKDGLKRGHVCTVCDKRCYNKSEVESHQKKNGSTIRYYCKLCEFETASEARMLKHLYSSIHNQSLPTIEVKNVEVGFRKAGTLRYCCFEGCNVTFCEIGKLQEHVNSIHKIEKESNMSTPRLDMASKWQCDCCYRFFRTVALLKQHQFSQRETKSYVCSICGAAKLNKTALTAHEMRHTGERPFACTVCDKRFASQTILTSHMKCHVPKQYECIECGEKFARGENLKRHIRHRHSEATYCCSYCPRKLKTREAQVLHERSHTGEKPFACRTEGCEKRYASITDRRRHEMASHTGERPHKCSYCVASFVRKRQLTIHERKHTGERPFVCNRCGKAFIDAPFLKKHSC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -