Wsmi049178.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- -
- Assembly
- GCA_029784165.1
- Location
- CM056646.1:180253244-180256047[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0012 0.14 14.4 2.2 2 23 316 337 315 337 0.97 2 11 7e-06 0.00077 21.5 1.1 2 23 344 365 343 365 0.97 3 11 0.48 53 6.3 0.1 1 23 375 397 375 397 0.91 4 11 0.28 31 7.0 1.2 1 14 483 493 483 503 0.76 5 11 0.0055 0.6 12.4 3.3 1 23 513 536 513 536 0.95 6 11 0.017 1.8 10.8 0.2 2 23 542 563 541 563 0.92 7 11 4e-05 0.0044 19.1 0.8 1 23 568 590 568 590 0.95 8 11 0.00042 0.046 15.9 0.1 2 23 599 621 598 621 0.97 9 11 0.00052 0.057 15.6 1.3 3 20 629 646 627 648 0.93 10 11 9.5e-05 0.01 17.9 0.7 1 23 659 681 659 681 0.99 11 11 0.001 0.11 14.6 2.6 1 23 687 710 687 710 0.98
Sequence Information
- Coding Sequence
- ATGGTGAAAACTGAAAGTTGTGCACTGTGTTTTACCACTAAATCAAAATGGTTCTTAGACATCTATTGCGAGGAGAACCAGTCTATGGATATTTCGGCCattatttcaaaacatttatGGTTTGAGTTGAAACCTAGTGGCCAATGCTATGTTTGCGCAGATTGTTGGAAAAATGTTtatgattttcatttgttctatTGCAAGTTGGAAAAACTACATTTAGAGACAAACGAACCTGATTCTCGAACAGTGCAAATTGATGTGCAACCAGATTTTGAATTTCATCCGATTGATGAAGTAAAAGTCGAACCTTTAGAcgaagatgatcaaaatcgcagcACCGATGGAGTTGCCGATAGCTCTATTATCGGTTTTAtcggtaaacaaacaacagaGGTGTCATCGTCTGAAGCAGTTCGTCCTAAAAGAAATACATCGACTCCAGTATGTCAATATAAAGCAGAGATTACAGAGTCTGATGCGGAAGATATAGATGGAGACTGTTTTGCAGACGATTTCGACGATGACAATGATTTGGATTATAAGACGGAGCCAAAAGAAGGAAAATTAAAAGCAGTAGAAattcccaaaataaaaaaacgtcgTGGCAGGCCTCCAAAAGCTATTGCGGTTAAAAAAGAGACGGATTTAGACACCTCAAATGAAACCGAGCAGGGTGAAAGTTCAAAAGATTCTGAATTGCGCCATAAGGTTAAAAAACGCAGAAAATTTAAGAAAAGATTAACTCGAAACAAATATGATTCAGATACTGGTTCAAATGATGGCGATCGTTCTAGAATAGGCAGCAAACGAGCCAGAGATGAAAGGTTGTTTAAATATATAGAAGAATTTGTATGTCATTTATGTCCGGAACGCGTTGAATTTGATCGGTTTCACCATGCTAATTTACATTATCGAGAATTCCACCAGGAACCGGCTTACTTGAAGTGCACAAAATGCGATCGAAAATGCTTTACGCCAGGTGGATTTATCAATCATATGGAAACTCACGATGATCCAGATAAAAACAAATGTAAAATTTGCGGTAAGGTCACTGATCAAAAAATCACATTAAAAAAGCACATGCGGGCCCATCGTCTTCAGATGGAGGAATCATTACCGTTCCCATGCGCGATATGTCCACGACGGTTTGAATTGGAACGTGCTCGCGACAAGCATGAGCGATTGCATGGAAGAAAAATTGtcataaaacgagaaaaaggACGTGATGATGAATTGATTGCGTTTTATAAGAAAATTTCTTGTGAAATTTGCGATGAAGAAAAGAACGATGGTGTAACGTACGAAAACTTTTGGGATCTTAAACTCCACATGGCTGGTGAGCACAACAAAACACCATACCTTAAATGCCCgatatgtttcaaaaaaaatgtttgccgGCAACAATTAATGATACATGTAGATGTACATGAGAATCCTGAACGGTACAGGTGCGATATATGCGGTGAAGTATTCCAGTTTCTCGAAAAGCACAAATTTAAGGCTCATGGCCAAACGGAACCCCAGGAGAAAAACTATAGTTGCGAACATTGTGGCAAAATGTTCCGTTGTGTGTTAAACCTTAGGAATCACATTGATCGCGTGCATGCTATTAAAGATGTTACATGCGATATCTGCAACAAACCTTTCAGCAAAAAAGCAATCAGTGCTCATAAACGTTCCGCTCATACCGACGAAATGTTCATGTGTGAGCAATGtccgaaaatgttcaaaacaCGCAGTGGTCTTGAATCTCACAAAAGCGAGCATGATGCTGAGTTACGCAAACCGGTGAAATGTGAAATATGCGGTAAAGAAATGCGTCGTGGTGCAAGCCTAACAAAACATATGAAAGTAATTCACTCAAAGGAGGCTCCCGTCAATTGCAATATGTGCGGCAAAGAGTTCCGCACTAAGTTTCACATGGTTCGCCATCGTACTAACACTTGTTCGGCAACTATCAATTCGAGACCATTCAAATGTGAAGTGTGCGGAAAAGGATTCTCGATGCGATTGACAATGACCGAACATATGACGACTCACACTAGAACGAGTTTGTACCagtgtgctttttgttttaaaacgtTTGGATACATCTCTAACCTTTACAAGCATCGCAAAAAGGCGCATCCGGAGGAGTGGCAAGAAGTACAGTCTCGCCCTGATCAAGGTATTGCCACTGTTATCGAAATAAGAAATTAA
- Protein Sequence
- MVKTESCALCFTTKSKWFLDIYCEENQSMDISAIISKHLWFELKPSGQCYVCADCWKNVYDFHLFYCKLEKLHLETNEPDSRTVQIDVQPDFEFHPIDEVKVEPLDEDDQNRSTDGVADSSIIGFIGKQTTEVSSSEAVRPKRNTSTPVCQYKAEITESDAEDIDGDCFADDFDDDNDLDYKTEPKEGKLKAVEIPKIKKRRGRPPKAIAVKKETDLDTSNETEQGESSKDSELRHKVKKRRKFKKRLTRNKYDSDTGSNDGDRSRIGSKRARDERLFKYIEEFVCHLCPERVEFDRFHHANLHYREFHQEPAYLKCTKCDRKCFTPGGFINHMETHDDPDKNKCKICGKVTDQKITLKKHMRAHRLQMEESLPFPCAICPRRFELERARDKHERLHGRKIVIKREKGRDDELIAFYKKISCEICDEEKNDGVTYENFWDLKLHMAGEHNKTPYLKCPICFKKNVCRQQLMIHVDVHENPERYRCDICGEVFQFLEKHKFKAHGQTEPQEKNYSCEHCGKMFRCVLNLRNHIDRVHAIKDVTCDICNKPFSKKAISAHKRSAHTDEMFMCEQCPKMFKTRSGLESHKSEHDAELRKPVKCEICGKEMRRGASLTKHMKVIHSKEAPVNCNMCGKEFRTKFHMVRHRTNTCSATINSRPFKCEVCGKGFSMRLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPEEWQEVQSRPDQGIATVIEIRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00949231;
- 90% Identity
- -
- 80% Identity
- -