Wsmi042079.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- -
- Assembly
- GCA_029784165.1
- Location
- CM056646.1:91247745-91249419[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.24 26 7.2 2.4 1 21 221 241 221 242 0.95 2 9 0.00013 0.014 17.5 0.3 1 23 249 271 249 271 0.98 3 9 0.23 25 7.3 1.0 1 19 321 339 321 342 0.85 4 9 0.0035 0.38 13.0 4.5 1 21 349 369 349 371 0.94 5 9 2.3e-05 0.0025 19.9 1.7 1 23 377 399 377 399 0.98 6 9 1.5e-07 1.6e-05 26.7 2.0 1 23 406 428 406 428 0.98 7 9 3.4e-05 0.0037 19.3 3.0 2 23 436 457 435 457 0.97 8 9 6.9e-06 0.00075 21.5 0.4 1 23 463 485 463 485 0.98 9 9 1.2e-06 0.00014 23.8 0.4 1 23 491 513 491 513 0.98
Sequence Information
- Coding Sequence
- ATGTCTTCGCCAGAAAGCCAACAGAAACGATGTCGTATTTGTACGGATATTCGAGACGAATTCGTGACTCTTGATTATATTGTGGAAGGAAAATCTCTCGCGGAAATGCTGCACTACTGTCTTAGGCTTGAGGTTTATAGGGATGATGGTTTGCCGTACCGATGTTGCATTGATTGCAAAGTAAGCTTGGAAGCAGCCTATAAGCTAATAGTTCGTTGTTTAGAATCTGCTGCATGGTTTCGACACTATCTTACTGGCGAAACATTCAAATCGCGaagTCTCGAAGATGTTGATGTAACGGGACTGAAATCAGAGATAGTCTTCGACGAGGCTAATAAATCTAGCGTCAATATTACAGATACTGATGTTAAAAGTGAAGGCAATGAAAGTTTAGAAAATGTAAATGAGCTGGATGATTCTGTTACAGAAGATGGTCAAGATGAAGACGAGCACAACAAATGCAGCATTGAGGAAGCCCACGATCAGGATAGACTGAAAGCTCTGCAATTGAAGACCACCAAATACGGAAAGGAAAAATCCCTTCCAAAGCGATGCTGCAAATGCAAAATTCACCTTAATAGTGTGAAAGAAGCTGAGGAACACTCTAAAACACATGTCGAGTCAAGAATTGTGGATCCTCAGAAAGTTGCAGCTCGACCCCACGAGTGCATGTTTTGTTTTAAACGCTACACTAAATTGCGAACGTTGATGCTTCACCAGAAAGAAATGTACGTCGACAAGCCCTTCAAATGTAAAGACTGCGAGGAAGATTTCAGTACTGATGTTCAACTGAGAGAACACATAGAAAACCACGGTAAAGACAAATCAAACCGAAAAGGACAGCTGCCAAAATGCTGTGCATGTTACGAGCAATTCGATACGGAAGAGATGGTGAAAAAACATGCCGAAGAAGTTCATTTCCCTGAAAGTCAAACCAGTGTGAATGACAATGATAACCAATTCGCCTGTGATGTGTGCCATCGTCGTTACAAGACTAAGCGAATTTTACTAGACCACAAGTCAAAACCTTATCGCACTAAGCAGTACCAATGCTCTCAATGTGGTAGAATATTCAGAGACAAGTGTGCTTTGTCGGATCACGAACGTTGCCATCAGGGGGAACGGCCCTTCATGTGCACGATCTGCTCGAAAACATTTGCCATAAAGGATTCTTTCCGAAAGCACGTCAGATCGCATACGATCGAGGAAGACCGCTTCAAGTGCGAAATTTGCGGGAAAGGGTTCAAAACGAAAGGCAATCTTAAGGATCATCATATAACGCACGCCTCGGATTACCGTCCCTTGAGCTGCAGTTTATGCTCGGCCACCTTCGCACGGAAGTCCTGCTTGAAATCGCACATGCGAATGCACACAGGCGAGAAACCGTTTAAGTGTAACATGTGTGATGCAAGTTACGCATTTTCTAGTGATTTGAAGCGCCATATTATGGCCCATAAGGGTATCAAACCGTACATTTGCAGTACATGTGGAAGGGGATACCCCAGACAGGATTACCTGCGAAAGCACATGGCCACCCACAATACGGCCAATTGA
- Protein Sequence
- MSSPESQQKRCRICTDIRDEFVTLDYIVEGKSLAEMLHYCLRLEVYRDDGLPYRCCIDCKVSLEAAYKLIVRCLESAAWFRHYLTGETFKSRSLEDVDVTGLKSEIVFDEANKSSVNITDTDVKSEGNESLENVNELDDSVTEDGQDEDEHNKCSIEEAHDQDRLKALQLKTTKYGKEKSLPKRCCKCKIHLNSVKEAEEHSKTHVESRIVDPQKVAARPHECMFCFKRYTKLRTLMLHQKEMYVDKPFKCKDCEEDFSTDVQLREHIENHGKDKSNRKGQLPKCCACYEQFDTEEMVKKHAEEVHFPESQTSVNDNDNQFACDVCHRRYKTKRILLDHKSKPYRTKQYQCSQCGRIFRDKCALSDHERCHQGERPFMCTICSKTFAIKDSFRKHVRSHTIEEDRFKCEICGKGFKTKGNLKDHHITHASDYRPLSCSLCSATFARKSCLKSHMRMHTGEKPFKCNMCDASYAFSSDLKRHIMAHKGIKPYICSTCGRGYPRQDYLRKHMATHNTAN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -