Basic Information

Insect: Wyeomyia smithii
Gene Symbol: RREB1
Assembly: GCA_029784165.1
Location: CM056644.1:7981023-7986577[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.4e-05 0.0081 18.3 0.3 1 23 140 162 140 162 0.99

2 14 0.00023 0.026 16.7 0.1 1 23 180 202 180 202 0.97

3 14 1e-05 0.0011 21.0 5.2 1 23 208 230 208 230 0.98

4 14 0.039 4.2 9.7 2.4 2 20 337 355 337 357 0.94

5 14 5.6 6.2e+02 2.9 1.3 1 21 402 422 402 423 0.88

6 14 0.067 7.3 9.0 0.1 1 23 572 594 572 594 0.97

7 14 3.3e-05 0.0036 19.4 0.3 1 23 603 625 603 625 0.99

8 14 0.0032 0.35 13.1 2.3 1 23 631 654 631 654 0.97

9 14 0.0019 0.21 13.8 2.1 1 23 1042 1065 1042 1065 0.95

10 14 0.00017 0.019 17.1 0.3 2 23 1392 1413 1391 1413 0.97

11 14 0.87 95 5.4 5.4 1 23 1419 1442 1419 1442 0.96

12 14 2.8 3.1e+02 3.8 2.8 1 23 1577 1600 1577 1600 0.94

13 14 0.024 2.6 10.4 0.6 3 23 1652 1672 1650 1672 0.95

14 14 0.0022 0.24 13.6 5.6 1 23 1678 1700 1678 1700 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.4e-05	0.0081	18.3	0.3	1	23	140	162	140	162	0.99
2	14	0.00023	0.026	16.7	0.1	1	23	180	202	180	202	0.97
3	14	1e-05	0.0011	21.0	5.2	1	23	208	230	208	230	0.98
4	14	0.039	4.2	9.7	2.4	2	20	337	355	337	357	0.94
5	14	5.6	6.2e+02	2.9	1.3	1	21	402	422	402	423	0.88
6	14	0.067	7.3	9.0	0.1	1	23	572	594	572	594	0.97
7	14	3.3e-05	0.0036	19.4	0.3	1	23	603	625	603	625	0.99
8	14	0.0032	0.35	13.1	2.3	1	23	631	654	631	654	0.97
9	14	0.0019	0.21	13.8	2.1	1	23	1042	1065	1042	1065	0.95
10	14	0.00017	0.019	17.1	0.3	2	23	1392	1413	1391	1413	0.97
11	14	0.87	95	5.4	5.4	1	23	1419	1442	1419	1442	0.96
12	14	2.8	3.1e+02	3.8	2.8	1	23	1577	1600	1577	1600	0.94
13	14	0.024	2.6	10.4	0.6	3	23	1652	1672	1650	1672	0.95
14	14	0.0022	0.24	13.6	5.6	1	23	1678	1700	1678	1700	0.99

Sequence Information

Coding Sequence: ATGGATCGCCGTCGCCTGTCAGCGCATTCCGATTCGTCCCAGGAACCGATGGATATAAGTTCCTCCAACCGGACGGCGAGCAGCACCGATACGAACAATTCTTCCctgaacaataacaacaacagcagtcggTTGTTGAGTAAAACCGCAGCCTCGGTAAGTGCGGATTCGGATAATGTTGATTCGGATGAGGACCAGCGTCGTTCGATGCAGCATCTGTTCCAGGCCCGTCACAACGCGCGAAGCGAAAATCTGCATCAGGTGATGGACAACATGCTGAGGCGTAAATTTCATAGTCTCAATaataacaactacagcggaAAGCACCTCCCAGCTTCGGTGGGTACAACGCTACTGCAGCAGCATCTGGCGGCAGCGGCTAATGATAACAACCTAACCGAGATGGAGGGTAAGAAATATGTGTGCCCAATTTGCGATATAGTTTCGGTGACGAAGCACGATTTTACCGAGCACATCCGGTCACACAACAACAGCAAATCATCGTCTGGCGATCGGGACAATGGCGAGGGTGGCCAGTTTGTGTGTAAAATCTGCTCGAAAGTCCTATCGTCCGCTTCCTCGCTGGATAGGCACGTCCTGGTGCACACCGGCGAGCGGCCCTTCAACTGTAAGTACTGCAATCTGACGTTCACGACAAATGGAAATATGCATCGACATATGCGAACCCACAAGCAGTCCGAGCGGGAGAGTTACGAGAGTGATGGGTCCACCGATAGTGGTGGGAGTAGTGCGGCTAGTAGTGGGATGTctaacaataacaacaatagCTACAATAACAACTACGATGGTGAGGGTAAGCGGAAGAATGCGGATGAGAATGTCCACTACAAGCGCAAGATACGCacgaataataataacaacattcTGGACGGAAGTGTCACAGAAGGGGTGCAGAAGTTCTGCTGCCCGGTTTGCGTCCGGAACGATTTCTCCAGCATGATCAGTTTGGAGAACCACATGGACCGCGAGCATCCGCAAATTCCAGCCAAATGTCGCCACTGCGAGATGGTTTTTAAGACCTATAAAGCCTTGAATGCCCATCGCTGTGGTAACAACAACTACCAGAATATTACCCCCGGGTTTAAGGACCTAACCTTTGTGGACTTTTCCAGCGAAAAGTTCCCCCTGATAGCGAAGAGTGTCTGCGAGCAGAGCATCCGGACGCCGGTTACGAGTCAGAAGTTTGAATGCTCTAAATGCTATCGAGCGTTTCCCTGCTCGAAGACGCTCGATATGCACGTGCGAGATTGTGGCGTGTCGGATTACAGCTCCAGCGGAGGTGGTGGCGAGAAGCGTAAGTGGAAAACCAGCGAAGCTTCCTCGGAGGACGACCTGAAGCGGGACGATTTCTTTGCCAATCTTGACCTGCAGAACAAATCCATGTCGACGAACATCTCTTCGAACGTTTCGGAAGCCCCCACCACGCCATCCTCCCTGGACAAGTCGTTCTCCTCGCCGATCATGGCCAGGGAGATTAAACAGGAGCCAAACTATTACCACCACAGCGGTGCCAACTATCCGCCCCAGCAGGATACCAAAGATCTCGCCGACATCCAGTCGATCATCAATGTCACCTCGTCCGGGGGATTCTTCCGACAGCTGGACAAAGACCCCTACCCACCCATGAAGGACGAAGAGGAAGCTCAGGATGCGTTCACCGCCGAGTTCCGCAAGATGAAACTTCGGGGTGAGTTTCCTTGCCGTCTGTGTACTGCTGTTTTTCCAAACCTGCGAGCCTTGAAAGGTCACAATCGCATTCACGTCTCGGCAGCCGGTTTGGGGCCCTATCGTTGCAACATGTGCCCGTACGTGATCAACGACAAAGCGACTTTGATTCGGCATATGCGATCGCACAACGGAGATCGGCCGTACGAATGTGCCCTCTGCAATTACGCCTTCACCACCAAAGCCAACTGCGAACGCCATCTCCGCAATCGTCATGGTCGGGCCACACGGGAGGAAGTCAAGCGCGCCATCATCTATCATCCCTCGGAGGATTCCTCCTGCGAGGATCCGCTCAAGAAAATGCAAATGTTCAACACCCCTCCGGGGGATTTTGATCGTGACGTGGACGTCGATCACCCCTCGGGTCGCAGCACACCGGTGTCCCATCTGAAGGAGATGCTGATGCCCATCCCGATGAGTCTAGTCACCAAAATCGATAGCACTCCGATTCCCACGACGCCAGCCAAAATTCAGGTCAAAAGCTTGGAGAAACTCAATCAATTAACGCCTCCCCAGGATCAGGACTACGAGAAGGAAGCTCCGCAAACTCCCATCTCTCAACCAACTCCAGATACGGCTCGTCCCATGGATCTTAGCATGGATGCGTTAGATTTGAGTAAGAAACCTGAACCGATCATTCGTCGAGAGCATGATGCCGACTCTGATCATCCTCGATCGGACGCCGAAGATGACGAAGAAGATCGCGTCGACGATGACGACGCTGAAGATGAAGACGAAGAGGAACAGCAGCCGGCCAAAATTCCCAAACTGGATCTCTCGCTGCTGGAGAAAAaccaacaacaaatccaactcATGCAGCAGAAGCTCTTCAGTGAAGCTCTCTCCAAACTGGACCCCGCTCACTATTTCCAGCTTAGCCAGCTGTACAGCCGCTTCAGCTTCCCGGCGGCAGCGGCCTTTCCCCTGCATCCACTATTCCTCCAAAACCCTCTACTGTGCGCTCCGGGCGCCCTCGGTGACCTGAAAAACTTCTTCCCCAAAGAGTTCCCCATATTGCCACAAATGTCCGGCGGAAGTCTCATCGGAAATCCATTCCACTCGCCAGCCGAATCACCGAAAAGCACTTCGGACACAACGCCGGTTAAACACGCTCAACAACTCTCACCCCAAGCCATGCCAAATCCTCCTCCTCCtgcgcagcagcagcagaagccGCAATCACAAATCCTTCCACCGCATGCGGTGCATTCGCACCATCAAGCCCCACCACCACCACCCCCACTACCACCGTCCTCTTCGGCTAACTCCTCCCCGATGTCAGCGATCCCCCTCGGCAACGGGCCCGTCAAAATGGTCATCAAAAATGGAGTCCTAATGCCAAAACAGAAGCAACGCCGCTACCGAACCGAGCGTCCCTTCGCCTGTGAACACTGTTCGGCCCGATTTACGTTACGCTCGAACATGGAGCGCCACATCAAACAGCAGCATCCCCAATTTTGGTCCCAGCGACAGCGTGGCGGACATCATATGATGAGAGGTCGTGGTCACTCGGTTTCCTCAATGGCTTCGAACGTTAGTCCAAGTTTGTCCCACCCCCATccgcatcatcatcatcattcgcaacagcagcagcagcagcaacaacaacagcaacaccaTCACCACCAATCGATGGCCGCAGCAGCAGCTGCTGCGGCAGCTTTTGGTGGAATCTCCGACCAGGTTAAGTACGCCATTTTGGCTCAACAGTCGGGTAAAGCTGCGGCCCATCATCGGCCCCCAGTTGCTGCGGATGCTGCCAGCACCATGCTGCAAAACATCATTGCTCAAGGACAGAATCCGTTTGGGTCGCATCATTCGATGCCACAGCATCAAGAGCATCAACATTCCAGCCGGGGATCGAGTGCCAATCATCATGCCGCCAACAATGGTCACCACGGGCTCGACGACGAGGAAGAGGAAGACGAACGGGAACTGGTGATCGATGAGGAGTTCCAACCGGAAGACCTCAGCAAGGGCAATGAATCCGATCAGGAGCTGCCGCAACCGGTGGTTGCTCGGAATCAGGAGAGTCCCGTTTTTCAGCATAAAATTTTGAAGCAAAAGCTGGAGGAAAGTAAGGAACAACGGCAGCAGGCAGCGAAAGCCGTTGCCGAAGGAATTCTCGAGCAGGCAATGCGTCAACGTAAGGAAGTGGAGAAAGAGAAGGAACCCAGCGCCCCTAAGGGGGCGGACGAGAGCGATCTGGTGTCCGTCTCAAAGCTGGTGGACAACGCAACGAACGTCGCCTTCGAGAACTATTTTAGCAGACCTGACGTGCCGCTGTCCCAGGATCAAAGCGACGAGGAGGGTCTGGTGGCGTCCGGCTCGGCTTCCGAGAGCAACAACTCCGGTACCGATGATCCGAACCCATCCACGCTGCAGCAGAAGAAAAAATCCGCCTACAGTTTAGCACCGAACCGGGTCAGCTGTCCGTACTGCCAGCGGATGTTCCCCTGGTCGAGTTCCCTACGGCGTCACATCCTCACCCACACCGGCCAGAAACCGTTCAAATGCTCGCAGTGCACGCTACTTTTCACCACCAAATCCAACTGCGATCGTCATCTGCTCCGGAAGCATGGCGACGTCGAGTCGGCCATGTCCATCCCCGTGCCGATCGACGATCTGCTGGATCCGAAGCCGGAACCGATTCCGGTTGCCGTTGCCGAAGCCATTGCCAAATCGAAAAGCACACCACCAACTTCTCGACCGGCCAGTCCGAAGCCGCCACAAATCACTGCTCAACCGCCTCCCACAGCGACGAAAGATGACGAATCCGAACCTCCGATCAAATCCAAACCAGAAAAAGTACCCCCACCAGCAGCACCAGCTGCAGCTGAAGAGGAAGAGGACGACGACGAGGAAGACCAATTCGAACCGATCCCCTCCCCGGAACCATCTTCGATGGTTAAAGTCAAAGAAGAACCACAAGCTCCGGCGGACGAAAACTCCTCGCTGCCGGCCATCAATTCGGATCTTCCCTTTAAGTGTCACCTATGCGAGGGCTCCTTCGCGGATCGGGTTTCCTGTCTGGATCACATCAAGCAGAACCACGTCCAGGAGTTTGCCCTGCTCATGAACAAGGTAACACTCGAGACGGAAAGCGAAGCACCCTCGGCCTCACCGGATGACGACGAAAGCGGTAACAATGGCGAGGGTTGTGGCCGGGGTGGAAAGTATCCCGACTACGCCAATCGGAAGGTAATTTGCGCCTTCTGTCTGCGTCGCTTCTGGTCGACGGAAGATCTGAGACGGCACATGCGAACGCATTCCGGCGAGCGTCCGTTCCAGTGCGACGTCTGCCGCCGCCGGTTCACCCTGAAACACAGCATGCTGCGCCACCAGCGCAAACACAAATGTTCCCGCCTGAATGGTTCCACGACGACCAACGGAAAAACCTTTGTCGCTTCGTCCGATTTCAGCGATGATGAACCGGAGGTGGCAGCGCCAcccccagcagcagcagcagcctgcACTCGATCCAAGACACAACACCAACAGCTGTTTGGCAGCAATTCGGCTGACCTGATCGGTAACCTGCTGGGCATCAGCGACCAGGGTATCCTCAACCGGATGCTGCTCGGGTCCGCCTCGGAAGCGGCCAAACTTCTTGGCGTGGAAAAGTGA
Protein Sequence: MDRRRLSAHSDSSQEPMDISSSNRTASSTDTNNSSLNNNNNSSRLLSKTAASVSADSDNVDSDEDQRRSMQHLFQARHNARSENLHQVMDNMLRRKFHSLNNNNYSGKHLPASVGTTLLQQHLAAAANDNNLTEMEGKKYVCPICDIVSVTKHDFTEHIRSHNNSKSSSGDRDNGEGGQFVCKICSKVLSSASSLDRHVLVHTGERPFNCKYCNLTFTTNGNMHRHMRTHKQSERESYESDGSTDSGGSSAASSGMSNNNNNSYNNNYDGEGKRKNADENVHYKRKIRTNNNNNILDGSVTEGVQKFCCPVCVRNDFSSMISLENHMDREHPQIPAKCRHCEMVFKTYKALNAHRCGNNNYQNITPGFKDLTFVDFSSEKFPLIAKSVCEQSIRTPVTSQKFECSKCYRAFPCSKTLDMHVRDCGVSDYSSSGGGGEKRKWKTSEASSEDDLKRDDFFANLDLQNKSMSTNISSNVSEAPTTPSSLDKSFSSPIMAREIKQEPNYYHHSGANYPPQQDTKDLADIQSIINVTSSGGFFRQLDKDPYPPMKDEEEAQDAFTAEFRKMKLRGEFPCRLCTAVFPNLRALKGHNRIHVSAAGLGPYRCNMCPYVINDKATLIRHMRSHNGDRPYECALCNYAFTTKANCERHLRNRHGRATREEVKRAIIYHPSEDSSCEDPLKKMQMFNTPPGDFDRDVDVDHPSGRSTPVSHLKEMLMPIPMSLVTKIDSTPIPTTPAKIQVKSLEKLNQLTPPQDQDYEKEAPQTPISQPTPDTARPMDLSMDALDLSKKPEPIIRREHDADSDHPRSDAEDDEEDRVDDDDAEDEDEEEQQPAKIPKLDLSLLEKNQQQIQLMQQKLFSEALSKLDPAHYFQLSQLYSRFSFPAAAAFPLHPLFLQNPLLCAPGALGDLKNFFPKEFPILPQMSGGSLIGNPFHSPAESPKSTSDTTPVKHAQQLSPQAMPNPPPPAQQQQKPQSQILPPHAVHSHHQAPPPPPPLPPSSSANSSPMSAIPLGNGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQFWSQRQRGGHHMMRGRGHSVSSMASNVSPSLSHPHPHHHHHSQQQQQQQQQQQHHHHQSMAAAAAAAAAFGGISDQVKYAILAQQSGKAAAHHRPPVAADAASTMLQNIIAQGQNPFGSHHSMPQHQEHQHSSRGSSANHHAANNGHHGLDDEEEEDERELVIDEEFQPEDLSKGNESDQELPQPVVARNQESPVFQHKILKQKLEESKEQRQQAAKAVAEGILEQAMRQRKEVEKEKEPSAPKGADESDLVSVSKLVDNATNVAFENYFSRPDVPLSQDQSDEEGLVASGSASESNNSGTDDPNPSTLQQKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSQCTLLFTTKSNCDRHLLRKHGDVESAMSIPVPIDDLLDPKPEPIPVAVAEAIAKSKSTPPTSRPASPKPPQITAQPPPTATKDDESEPPIKSKPEKVPPPAAPAAAEEEEDDDEEDQFEPIPSPEPSSMVKVKEEPQAPADENSSLPAINSDLPFKCHLCEGSFADRVSCLDHIKQNHVQEFALLMNKVTLETESEAPSASPDDDESGNNGEGCGRGGKYPDYANRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCDVCRRRFTLKHSMLRHQRKHKCSRLNGSTTTNGKTFVASSDFSDDEPEVAAPPPAAAAACTRSKTQHQQLFGSNSADLIGNLLGISDQGILNRMLLGSASEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01462437;
90% Identity: -
80% Identity: -