Wsmi037162.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- -
- Assembly
- GCA_029784165.1
- Location
- CM056646.1:13597864-13600779[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0023 0.25 13.6 0.1 2 20 236 254 236 256 0.94 2 15 0.0089 0.97 11.7 0.6 1 21 263 283 263 284 0.95 3 15 0.52 57 6.1 4.8 2 23 398 420 398 420 0.94 4 15 0.002 0.22 13.7 0.1 1 21 430 450 430 451 0.95 5 15 0.011 1.3 11.4 1.0 2 22 459 479 458 483 0.92 6 15 0.26 28 7.1 2.6 2 23 563 585 563 585 0.89 7 15 0.00035 0.038 16.1 2.6 1 23 625 648 625 648 0.97 8 15 1.5 1.6e+02 4.7 2.0 1 23 688 713 688 713 0.85 9 15 0.0061 0.66 12.2 0.8 2 20 730 748 730 750 0.92 10 15 0.0002 0.022 16.9 1.3 1 23 756 779 756 779 0.98 11 15 7.9e-06 0.00086 21.3 0.1 1 23 786 808 786 808 0.97 12 15 1.5e-05 0.0017 20.4 0.7 1 23 814 837 814 837 0.95 13 15 7.6e-06 0.00082 21.4 0.4 1 23 843 865 843 865 0.97 14 15 0.44 48 6.4 5.5 1 23 871 894 871 894 0.96 15 15 0.0059 0.65 12.3 0.3 1 23 900 922 900 922 0.96
Sequence Information
- Coding Sequence
- ATGCGTAAACTTTGCAGAATTTGTAATTTATTGGGAGTTGGTGTAGACGGTACGGTACACCTTAAAATGTGCAACATATTTTCCGCAGCAGAGGAAACACCACTAGCAACATTAATGCAAGATTTGGTTAACATTCAGATATCAGACAACGGTCAACGATCACAGTACATCTGTTTCGATTGTATGCAGCAGGTTAAAATAGGTCATCAAATTTGGAAAAGGATTCGTGATGTGGAACTGCAGCCATGTCCAGTGATTacaaagaatgaaaaaaatcgtgaTGGTGGATCAGTCGAATTAGAGTTTGTTCGAAACACCGAAATTAAACCAGAACAAATACCGGAAGGTGAAACTAAGGATGACTATCTCTACGAATTTTTGGAAGACGAGTTCGTGACTGATGATGGTAATAATTCTGCAGTTACAACATTCACAAAGGATGCTGAGCGTGATTCCTGTTCTGAAGATCGTGAATATTCTGAAGAAGATCCCACGAAATTATCCCTGCAACGTACCATGAGAAAGGTTCAATTTGAAATGCCCAACCCACAAGTCGTTCTACGAATCGACGATATGCCAGACCATTTAGTCGTAGAAGTGAAAGGCGACCGATGCTGCGGGTGTAGTTTTGTTGGAGAAAACAGAAGAGAACTTTTGCAGCACTCTACTAGTGCACACTCTATCGAAATCGAAGGAACTGGAAATTACTGTCCCATTTGTTTCTACAAATTTGCAACAGAAAACAGCCTAACGAGGCATATCGACGCATGCAAATCGAGAAGCATTTTTGTTTGCAAGAACTGTGAGCAGTACTTCAACCGACAACATCAGATTGAAGCTCATTTGCAGATTTGCAAAATAGCAGGTATTAGTGGCGAAAAAGTGGAGGAGTTTGTTGAATCAACCGATGGTGAATATGATTCGAATGCTGAGTTTTTgctgagtgaaagtgaaaatgaaaGTAACGTTGACAGTGATGAAAACTCAAAACACCGAAATAACGATTGGACTGTTTCAATGGAGCAAACAGAATTTTCATCTGGAAGCGCACAGTCAACAAGTTATCCTAACTTCATAAAATTAAGCAACGTAATTGATTGTCATGGTGTGCAACCTAGTAGTATCCCTGAGTCCCAGATTGTACAACGGGTTACCTTTCAAACGTTTCAGTATCTCCGATTGACAGGCGAGCGTTGTTGTGGATGTGATTTTATTTGCTCTAAACGAGACCAACTCTTCAATCATGTTCAACAATTGCATGTACGAAAGGTTAACCTGTCCAAAGAATTTATTTGTCCAATATGCTATCAAAGTTATGCTAACGAAAAAGAACTTTCGAAGCATATTAACTATTTCACCAGCAAAGATTTGCTTATTTGTTCTATTTGCGATGAAGTATTTTGTGGTATTGAAGCTCTGAATCACCATCAAAAGAAAAGCGTGAAACATACGCAAAATTTGCTTCAAGCAAACCAAGAAAAGATGCTAACCACAACCGAATTCAACGACGAAGATGTGTTGAAACTATTCAAAGCTGAAGTGACGGACAAAATTAAAGCTAAAACTCGCACGAGATCTAACAGACGGTCCATTACGAAGCACCGACATTTAACAATGCCAGACACACAACTCATTGAGCGAATTGAGGAATATGAAAACTATAAGGTAATTACCGTAACTGGAGAGCGCTGCTGTGGGTGTGGACAGTTTTTCGAAACGTACAATGAGCTACTTCAACATGGTCACCAAATCCACCTGATAGACAACGCAGATGCTGCTGGAGAATACCAATGTATTGTTTGTTTCGCACGTTTTGAGTTTGTCAGAGGGCTGTTGTTGCATCAATCATCGCGCAAGTCGGTTAGTAAACTCTTCCACTGTAATATCTGTAATTTGATCTTCTCCAAGCAATTTACTATGAATAGACATATACAGACTGCTCACTCAATAGATCATGATCCCGAAAACAACGCACAACAAATTGGGTTGAAGCAAAATCAAGACATAGTCGAGACTCTCCCCGTCAATGTGCGAAACAAGCAATCTAAAATCAACGGTAAATACGTTTGTTGTTTACcaaaatgcgccaaagaattTTCCAGCGAAGATTTACTGCTTGATCACTGTTCAACAGATCATTCCGGTAAGCGACGTGAAAATGAAGCTGAGAGAAGTAGCGAGTCGAACGTCTGCCCGGGATGTAATAAATCCTTCGAAAACACCACCTGCCTTGTATGGCATCGATTTACGCGCTTCACTAAGCACTATCAATGTCGTTTTTGTGATCAAACATTTACACGTTGGTCTGTCTACCGAGAGCACGAAAACACAGTCCATTTGGGCAAAACAACAGAATTCCCCTGCGAAACTTGTGGAAAGGTGTTCCGAACAGCAGCACGTTTGAAGGCACACCTGGAGATACACTCTAGTTTACGGAAACACGTTTGTAGTGATTGCGGAGCCAGCTTCCGAAACAAGGGAGTTCTTAAGCGTCACAGGCGAGCCGTACATTCCACCGAATTTCTCTTCGACTGCAATCAATGCCCGAAAAAGTTTCCCACCCAAGAGCAGCTGAACGCTCACAGTCGTGTGCACTCAGGAGCTAAACCGTACAACTGTCGGTTTTGTAAACGTGCTTTCTCGCACTTTACCGATCGCAAGCGACACGAAATGTCCACCCATACTGGCGAACGACCCCATCAGTGCATTTACTGCCCGGCGGCATACGTGCGCAATCGTGAGCTGATTATTCACATGCAGAAACATGAAGTGTTGTAG
- Protein Sequence
- MRKLCRICNLLGVGVDGTVHLKMCNIFSAAEETPLATLMQDLVNIQISDNGQRSQYICFDCMQQVKIGHQIWKRIRDVELQPCPVITKNEKNRDGGSVELEFVRNTEIKPEQIPEGETKDDYLYEFLEDEFVTDDGNNSAVTTFTKDAERDSCSEDREYSEEDPTKLSLQRTMRKVQFEMPNPQVVLRIDDMPDHLVVEVKGDRCCGCSFVGENRRELLQHSTSAHSIEIEGTGNYCPICFYKFATENSLTRHIDACKSRSIFVCKNCEQYFNRQHQIEAHLQICKIAGISGEKVEEFVESTDGEYDSNAEFLLSESENESNVDSDENSKHRNNDWTVSMEQTEFSSGSAQSTSYPNFIKLSNVIDCHGVQPSSIPESQIVQRVTFQTFQYLRLTGERCCGCDFICSKRDQLFNHVQQLHVRKVNLSKEFICPICYQSYANEKELSKHINYFTSKDLLICSICDEVFCGIEALNHHQKKSVKHTQNLLQANQEKMLTTTEFNDEDVLKLFKAEVTDKIKAKTRTRSNRRSITKHRHLTMPDTQLIERIEEYENYKVITVTGERCCGCGQFFETYNELLQHGHQIHLIDNADAAGEYQCIVCFARFEFVRGLLLHQSSRKSVSKLFHCNICNLIFSKQFTMNRHIQTAHSIDHDPENNAQQIGLKQNQDIVETLPVNVRNKQSKINGKYVCCLPKCAKEFSSEDLLLDHCSTDHSGKRRENEAERSSESNVCPGCNKSFENTTCLVWHRFTRFTKHYQCRFCDQTFTRWSVYREHENTVHLGKTTEFPCETCGKVFRTAARLKAHLEIHSSLRKHVCSDCGASFRNKGVLKRHRRAVHSTEFLFDCNQCPKKFPTQEQLNAHSRVHSGAKPYNCRFCKRAFSHFTDRKRHEMSTHTGERPHQCIYCPAAYVRNRELIIHMQKHEVL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -