Wsmi002235.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- -
- Assembly
- GCA_029784165.1
- Location
- CM056644.1:24481989-24483070[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0023 0.25 13.6 0.2 5 23 54 72 53 72 0.96 2 10 0.00024 0.026 16.7 0.4 3 23 80 100 78 100 0.98 3 10 0.0076 0.83 11.9 0.2 1 23 104 126 104 126 0.97 4 10 0.00019 0.021 17.0 1.0 1 23 135 157 135 158 0.97 5 10 6.7e-05 0.0073 18.4 0.3 1 23 161 183 161 183 0.96 6 10 3.3e-06 0.00036 22.5 0.5 2 23 190 210 189 210 0.98 7 10 0.00027 0.029 16.5 0.1 1 23 216 238 216 238 0.98 8 10 4.2e-06 0.00046 22.2 3.5 1 23 244 266 244 266 0.99 9 10 0.00011 0.012 17.7 0.1 3 23 274 294 272 294 0.97 10 10 8.2e-07 8.9e-05 24.4 0.7 1 23 300 322 300 322 0.98
Sequence Information
- Coding Sequence
- ATGAATACTTGCCAAATAAACGAAAACTCCAACGGTTGCAAACAGGAAAGTTTTATTAAAGTCGAAGAAACACGCTTAAATgaaccgatcgatctgaaaactAATAATATTAAACAGCTTTTGCGTACGCACTCCGGCAAGAAGTCTTTCGACCGTGATGAATGTGAAAGAAAGTTTCCTCGTCGGAGTTCTCTTATTCTGCACAAGCTCACTCATTCGGATGATGGATCTTTCGGCTGCGAGATCTGCAACAAAAGGTTCGAGGAAAAGGAGGTTTTGACGCAGCACCTAAAAATGCACGAGCGGAATTTTAAATGTGATGTCTGCGGTAGAGGTTTCCTTTATCCGTATCTAGTGAAGCTGCACGCGCGGCTACACTCTGATGATCCGGCCGTGCGAAAATTCAAATGTGAGATTTGTGAGAAAGAGTACATTACTCGGTCCAATTTGAACTTTCACCTGGAAAAGCACCAAAAATCTTTCGCGTGTGACGAGTGCCCGAAAACATTCGTTTACTATAAATCACTACGCGAACATAAGGCCGTACATACCAATAAACAAGCTAATAAATGTGAAATTTGTGGGAAAAGTTACCCGAAAAGTTACCTCAAGGCTCATATGCGAATGCATGCTGGCAATCAGCGCTACAAATGCGAAGTATGTGGAAAAATCCTCTCGTCCACAAACGAACTCGATATTCACACGAAAGTTCATCGCGGCGCAAAACCTTACAAGTGCGAGATTTGCGACTTAAGTTGCTCTAGCAACTTTTCTCTGAAGACACATCTACGGACGCATACCAACGAGGATCCTTTTGGTTGCGACGTTTGTGATAAACGATTTGCAGCGAAAGGCAGCCTGAAGTATCACATGGCAGTGCATGAAAATAATCGACCCCACCAGTGTGACATCTGCGGGAAAGGATTTATTACCAGCTGGAAATTGTTGGCGCACACGCGCACGCATACTGGTGCATCCTTGAATTCTCGTTTGATGAGTAGTGGGAATGATGAAAAGTAG
- Protein Sequence
- MNTCQINENSNGCKQESFIKVEETRLNEPIDLKTNNIKQLLRTHSGKKSFDRDECERKFPRRSSLILHKLTHSDDGSFGCEICNKRFEEKEVLTQHLKMHERNFKCDVCGRGFLYPYLVKLHARLHSDDPAVRKFKCEICEKEYITRSNLNFHLEKHQKSFACDECPKTFVYYKSLREHKAVHTNKQANKCEICGKSYPKSYLKAHMRMHAGNQRYKCEVCGKILSSTNELDIHTKVHRGAKPYKCEICDLSCSSNFSLKTHLRTHTNEDPFGCDVCDKRFAAKGSLKYHMAVHENNRPHQCDICGKGFITSWKLLAHTRTHTGASLNSRLMSSGNDEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -