Wsmi019728.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Wyeomyia smithii
Gene Symbol
K02A2.6
Assembly
GCA_029784165.1
Location
CM056645.1:46801632-46807572[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00019 0.021 17.0 1.0 2 23 1003 1024 1002 1024 0.97
2 12 2.1e-06 0.00023 23.1 1.6 2 23 1036 1057 1035 1057 0.98
3 12 0.00012 0.013 17.6 4.4 1 23 1066 1088 1066 1088 0.98
4 12 3.6e-06 0.0004 22.4 1.3 1 23 1094 1116 1094 1116 0.98
5 12 0.00047 0.051 15.7 0.3 1 23 1122 1144 1122 1144 0.98
6 12 1.2e-05 0.0013 20.8 0.7 1 23 1150 1172 1150 1172 0.98
7 12 0.00014 0.015 17.4 2.6 2 23 1211 1232 1210 1232 0.97
8 12 1.6e-05 0.0017 20.4 1.9 1 23 1242 1264 1242 1264 0.99
9 12 9.9e-05 0.011 17.9 1.2 1 23 1270 1292 1270 1292 0.99
10 12 0.00024 0.026 16.6 3.9 1 23 1298 1320 1298 1320 0.98
11 12 0.00047 0.051 15.7 2.8 1 23 1326 1348 1326 1348 0.96
12 12 1.4e-05 0.0015 20.5 0.2 2 23 1355 1376 1354 1376 0.98

Sequence Information

Coding Sequence
ATGGGGCATTTCGCCAGTCAGTGCTTTGGAACAGCACTTAATAGTGGAACGCGGAATAAAGCCGTGAAAACGATAAGTTGTGAACTAGAAGAAGAAGAACAGGCAGTGCAAGAACTGTTTATTGGAAATATTGAAGACGAGGACGAGAGTGTCGAAGAGGCATGGTACGAGGAAGtgaagttgaaaaacaaaaaagtgctattcAAACTCGACAGTGGTGCAGCCTGCAATGTTATACCAATCAATATTTTTCGTGATCTAGGGGAAAAGCTATTTTCATCCAAGACCAAACGGCTAGTCTCCTGCAGTAACCACAAAGTGAATGTGGCTGGTGAAGCACACTTGCCGATTATAGTGAGAGGTAAAACGGATGAAGCAGTTTTCAAGGTGGGGCTTGGCTGTGTTAAAGGATTCGTTTACGACATTGATCTAGTGGAAAATCCGATTTTCGTTACTAATCCACCACGAAGAATTCCTCACTCGCTTCGACAGGCAGTCAAGGAAGAACTTGATTCGATGGAAAAAATGGGTGTGATTCAGCCCATCAGTGAGCCAACGCCAGTTACAAACGCGCTGGTTATAGTCAGACAAAAAGGACACATCGTGACGCAGCAAGGACTTCAGGCTGATCCAGAAAAATTGCTAGCAATTCAGCATCTGAAACGACCGACTAACAGATTAGAAGTACAACGCGTACTAGGGACAGTAAATTACGTGGGTAAGTTCATTGAGAATCTCTCAGCTGTAACTGAGCCTCTGCGGAAATTGTTGATCAAGGATGTTGAGTGGTTTTGGGATCGAGAAAAGGAGGATGCCTTCTTGAAAATAAAGCAGCTTATGACATCACTTCCCGTATTGAGTTTTTATGATGTTAACGAAGCGGTAACGCTTTCGGTAGATGCCAGTTCTAAAGCGTTTGGTGCGGTACTGCTACAAAAAGGGAAACCCGTTGCGTACGCATCAAAATTCTTGTCTGCAGCTCAAGAGAATTATCCTCAAATCGAAAAGGAAGCGGCTGCGATTCGCTTTGCAAGCAATAAATTTCACCAATATGTCTATGGCAAAGAACTAGTAATCGAGACCGATCACAAACCACTTGAGTCAATCTCCAGAAAATCATTGGATAGAGCTCCTCCTCGTCTCAAAAGAATTTTACTCGACGTCATTCAATACGGCCCTAAGATTCAAtacaaaaaaggaaaagaaattcTATTGGCAGACATTCTTAGCAGAGATGTTGATGACAGTTATATTCCAGACAAAACAGATGAATTGGAAGTGCATGTCGTGCTTCAAATGTCCAAGTCCGCTAAAATAGAGTTAGAGAAAGAAAGTGCAAAGGATCCTAAAATTCAGCAACTCACAAAAATAATTATGTCTGGTTGGCCTGACGATAGACGAAAATTGCCCACTGAAGTACGCCCATACTGGAACTATCGCGACGAATTGTCATGCTATGAAGGCTTGGTCTTCAAATCACACCAAATTGTCATCCCACAGAGCCTAAAACGAAAGATGCTGGAGATTATACATTCAGGACATACTGGTATACAAGGCTGTATGAACAGAGCGAAGCAGCAGCTTTTCTGGGCAGGAATAAACGCGGATATAAAGCATATGGTCGTGACTTGTTCTGTATGTGCAAAGCATCAACACTCAAACCAAAAACATGTCATAATCAACAATGAAATACCAACTTTACCCTTCGAAATTGTCGGCTCTGACCTTTTTCACTTTCGGGGAGAGGAGTACGTTTTGATTGCAGACAGTTATTCAGGTTATTTTGATTTTGAACAACTCAGAGAAACCTCGAGCAGGTctgttatcaaagttttaaaacGATGGTTTGCTTCTCATGGAGTTCGTCGAACACTATATACAGATAACGGCCCGCAATATTCTTCAAAAGATTTCGCCGACTTCAGTGAGCAATGGTCCTTCGATCACATCACATCTAGTCCTTACTTCCCAAGAAGCAACGGTTTGTCGGAAAGATTCGTTCAAACTGCAAAAACTTTGCTCAAAAAGAGTTTCGAGAACAACACAGATGTGGACTTAGCTTTGCTATTATTTCGAAATACGCCAAGGGATAAAGAACTAGTATCGTCAAGTCAACGTTTAATGGGACGTCGGTTAAGAACACCTTTACCAAGCACGCATAAAAGTTTAGAGCCCACTATTGTCGACAGGGTCTCGGAAAATCTTAAAGCAAAACGATTACAGCAAAAGTTTTATGCAGACAGAGGAGGTAGGGAAGCTCCAGAGTTTACTGAGGCGCAGCAGGTAATGGTGCAGAACAGTAAGTCACGAATATGGGAGGCAGGCGATATTGAAAAGAAACTAGTGCAACCAAGATCTTATCTAGTTAAACTTGCAGATGGTCAAACTATACGTAGAAATGCGCGGGACATCAAAGAATCACATTCGTTACCGTTACCGTCCATGGACCAGCATTCAATAGCATATGATAACTTCATCATCCAACGGAAAACTGTTCCCACACGGCGCCCGTCAGAAGAGACGATTGGAGACCAAGTTTCAACTGATCCAGCAGAGCAACAAAACGAACATCAAATCGAAACACAAAATGATTACTACTCCAAGGAAATTTGCATAGTGTGTCTAAGCGATTTGTCCAATGCGGAACGATTTCGATTGCGGTGCCTAAAATCGGTAGAAATTTTGATGCATGAGCAATGCGTTGTCGAAGATTTGCAACAAAAAACCACATTTGATACGCCGGTGTCAGAAAGTTTGATACCAacagaattaaaaataaatgccAGCCATCGCTCCGAATTCGATGAGAAAAGTGAGTTTAAAATCAAACAAGAATCTCCTGCTGTCGATTTGTTGTTCACTTCATCTGTTGCTAAAATAGAAGATGATCCAGAAGATTTGGGAATCGAATACACAATTCGTTCCCAATACTTTCTAGATACAGCCGCCCTTAATGGTCACAGCGAAATGCAGAACGACAAAGTTTCGGCTGTTGAAAGCCCACTTCAATGTAGCGTTTGCAAAGAAGAGTTTGATGATAGTGAAACTCTTCATCGTCACATTCGATTACATTTTCAGGATGATAAACACAAAAAGCGGCTGAATAAATGTCCTACTTGTGATAAGATTTTCAGCGGCCGTTACCATCTGGAGAGACATATGATTACTCATAACGTAACCTACAGTGAGCGGCCTCATAAATGTAATGTATGCGAGAAACGATTTAATTTAAAGCGAACCCTCCAAATACACCAGCGAACACACAGCGGTGAAAAGCCATATAATTGTGACATTTGTGGGCGCACATTCAGAACCACGAGTGTTCTTGTGAAACATAGGCGCACACACACTGGAGAAAGGCCGTATGTGTGCGACGTTTGTGAAAAATCTTTCATCAGTGGTAACGAGTTGAAGAATCACAAGATTAAGCACACCGGTAACTTACCTTTCAGTTGCAAAATATGCGACAAAAAGTTCATTATATCCAGTGCCCTTCGCCGACACTTAATTCGACATGAAGAAGAAAAGGAAACTAAGTCAAAAATTGGAAAACGCACGTTACAAATCAAACGTACGAAGCGCACGCGCAAATTTGATCGCGTCAAGCACAAGAAAATGGTTCAACCGAAAAAATGCAGTTTTTGTGATAAAACATTCCGCTTCGCTTATGCACTAAAACGACACGAGACCACACATTCCTTTGTTGACACCCAAGAAGGTCCTTTCAGATGCAGTGTATGCGATAAAGAGCTGAGAACCTCCTACTTATACAAGCGTCATATGCGAATACACGATACCGATCAACCGTTCAAGTGTGAAACCTGCGGCCGAACATTTTCTCTGATGAACGTACTGACGAGACACGTCCGGACGCACACTGGCGAGCGACCCCACAAGTGCGACTTTTGCGGTAAAGCTTTCACCACCAGCTGCGCCGTTGTTAGACATAGACGGGTTCACACCGGCGAAAGACCACATCACTGTGGAGTTTGTGGCAAAGGCTATATCACTCTTAGTCAACTCAAGAACCATCAGTACAGCCATTCCGGAGAATGGCCCAGCCAGTGTCCTATTTGCGGGAAGGGGTTTATCAGGGAAACCCTAATGAGCCAACATATGCGAAGCCATGGCGTTTCAACGTAA
Protein Sequence
MGHFASQCFGTALNSGTRNKAVKTISCELEEEEQAVQELFIGNIEDEDESVEEAWYEEVKLKNKKVLFKLDSGAACNVIPINIFRDLGEKLFSSKTKRLVSCSNHKVNVAGEAHLPIIVRGKTDEAVFKVGLGCVKGFVYDIDLVENPIFVTNPPRRIPHSLRQAVKEELDSMEKMGVIQPISEPTPVTNALVIVRQKGHIVTQQGLQADPEKLLAIQHLKRPTNRLEVQRVLGTVNYVGKFIENLSAVTEPLRKLLIKDVEWFWDREKEDAFLKIKQLMTSLPVLSFYDVNEAVTLSVDASSKAFGAVLLQKGKPVAYASKFLSAAQENYPQIEKEAAAIRFASNKFHQYVYGKELVIETDHKPLESISRKSLDRAPPRLKRILLDVIQYGPKIQYKKGKEILLADILSRDVDDSYIPDKTDELEVHVVLQMSKSAKIELEKESAKDPKIQQLTKIIMSGWPDDRRKLPTEVRPYWNYRDELSCYEGLVFKSHQIVIPQSLKRKMLEIIHSGHTGIQGCMNRAKQQLFWAGINADIKHMVVTCSVCAKHQHSNQKHVIINNEIPTLPFEIVGSDLFHFRGEEYVLIADSYSGYFDFEQLRETSSRSVIKVLKRWFASHGVRRTLYTDNGPQYSSKDFADFSEQWSFDHITSSPYFPRSNGLSERFVQTAKTLLKKSFENNTDVDLALLLFRNTPRDKELVSSSQRLMGRRLRTPLPSTHKSLEPTIVDRVSENLKAKRLQQKFYADRGGREAPEFTEAQQVMVQNSKSRIWEAGDIEKKLVQPRSYLVKLADGQTIRRNARDIKESHSLPLPSMDQHSIAYDNFIIQRKTVPTRRPSEETIGDQVSTDPAEQQNEHQIETQNDYYSKEICIVCLSDLSNAERFRLRCLKSVEILMHEQCVVEDLQQKTTFDTPVSESLIPTELKINASHRSEFDEKSEFKIKQESPAVDLLFTSSVAKIEDDPEDLGIEYTIRSQYFLDTAALNGHSEMQNDKVSAVESPLQCSVCKEEFDDSETLHRHIRLHFQDDKHKKRLNKCPTCDKIFSGRYHLERHMITHNVTYSERPHKCNVCEKRFNLKRTLQIHQRTHSGEKPYNCDICGRTFRTTSVLVKHRRTHTGERPYVCDVCEKSFISGNELKNHKIKHTGNLPFSCKICDKKFIISSALRRHLIRHEEEKETKSKIGKRTLQIKRTKRTRKFDRVKHKKMVQPKKCSFCDKTFRFAYALKRHETTHSFVDTQEGPFRCSVCDKELRTSYLYKRHMRIHDTDQPFKCETCGRTFSLMNVLTRHVRTHTGERPHKCDFCGKAFTTSCAVVRHRRVHTGERPHHCGVCGKGYITLSQLKNHQYSHSGEWPSQCPICGKGFIRETLMSQHMRSHGVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-