Wsmi002496.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- -
- Assembly
- GCA_029784165.1
- Location
- CM056644.1:27728585-27734503[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00093 0.1 14.8 0.6 1 23 81 103 81 103 0.95 2 12 1.8e-05 0.0019 20.2 3.9 1 23 147 169 147 169 0.98 3 12 5.2e-05 0.0057 18.7 1.2 1 23 175 197 175 197 0.98 4 12 0.00044 0.048 15.8 2.0 2 23 204 225 203 225 0.97 5 12 0.0011 0.12 14.6 3.0 1 23 244 266 244 267 0.95 6 12 0.00059 0.064 15.4 2.1 2 23 275 296 274 296 0.97 7 12 1.7e-05 0.0019 20.2 3.1 1 23 302 324 302 324 0.96 8 12 1.3e-05 0.0014 20.7 1.1 1 23 330 352 330 352 0.99 9 12 9e-05 0.0098 18.0 1.1 1 23 358 380 358 380 0.96 10 12 5.2e-06 0.00057 21.9 0.3 1 23 386 408 386 408 0.98 11 12 0.0074 0.81 12.0 0.5 2 23 417 438 416 438 0.96 12 12 2.1e-07 2.2e-05 26.3 1.0 1 23 451 473 451 473 0.98
Sequence Information
- Coding Sequence
- ATGGAGGAAGAACCGAGTGCGataaaagtggaagaggttacGATAGCTGATGATATGGGGTGTTGTGATCTACCAATCATAAAAAATAATGAGTCGAGTGTAGTGAAAGATGAGCCCGAAACCGGTGAAATGGAAACGACTGCAGCAGCTGACGGCGAAGTTGACGCTTCTAATTCAAGCCACGCGGAAGTTTTGGAATCGTACCACACGGACGATGGAGAGCATACCGAAGGATTGTCGTTTGAGTGTGGAATCTGTAGCAAATCGTTCAGAACTATCGCTAGACTAGAAAGCCATAAAACGAATCACACACGAAAGACACAATATCAGGACGATGAGCAACTGTTTAAATGCGACATCAGTGCCGAATCAACCAACTCTTCCAGTATTTTGCACCTGCTCAAGAAATCTCACGCAAAATATACACCGGAAAAGAACTTCACTTGTGAAATATGTGGTAAAGATTTTCACTTCAAGTCACATTTGGCGTATCACCTGAGAGTGCATAGTGCGGATGGTCCTCACAAGTGTTTGGTTTGCGAAAAAAACTTCATATTCCCTAGTGTGCTCGTAAGGCATATGCGTAGCCACAGTGATGAACGTCAGGTTCAGTGCGACATCTGTCCCTCAAGATACAAATCACAACACGCActaaaaaagcataaaaaaatCCACCTGCCAGATTTAGAAATGAATTCCACTGAGTTGGACCCCGGTTTAAAAGGTCCCCACAGATGTGGCGTATGCAGGAGGGTCTATATTAACAAGGATACGTTGGaggaacataaaaaaattcatcacaaaaagaaaatattagATCTCAAGTGCAAAATTTGCGATAAACAGCTTAAACAAATGTCTCGTTTTACAATCCATATGCGTAACCACACAGGCGAACGACCTTTTGAATGTGAAACATGTGGCAAATCTTTTAAAACAAGCAGCTGCCTTGGCAGACATAAAATAAATCACACACTGGAGAAAAGCTTCAAATGTGAAGTGTGTGGGAACGATTTCTACTTGAGCACACAACTGAAGAAGCACATGCGTGTGCACAGCACAGACCATCCGTTCGAGTGTACGATCTGTGGAAAAAGCTACAAAGCTAAGGCTTCGCTCCAAATGCACGGGCACAGTCACAGCGATAAGCGTCTGTTTCGTTGTGACATCTGTGGATTGTCATACAAAACACCCAACAGTTTGGCAACACACAGAAAAATACACACGCTCGTTCCGACTGGTTCTTTGCAGTGTGATGTATGCAAGAAAATTTTATCCACCGCGAATATTTTGAAGAGGCATCAAAAGCTTCATCTTGGACAAAACAGACAGTACACAGACCAGCGTCCGTACAAATGCGGTACTTGTGGCAAAACTTTTGCCTCGCAACGCAACTGGAGCCGGCATATGCGTGAACACAACACGTCAAGCAATTCATGA
- Protein Sequence
- MEEEPSAIKVEEVTIADDMGCCDLPIIKNNESSVVKDEPETGEMETTAAADGEVDASNSSHAEVLESYHTDDGEHTEGLSFECGICSKSFRTIARLESHKTNHTRKTQYQDDEQLFKCDISAESTNSSSILHLLKKSHAKYTPEKNFTCEICGKDFHFKSHLAYHLRVHSADGPHKCLVCEKNFIFPSVLVRHMRSHSDERQVQCDICPSRYKSQHALKKHKKIHLPDLEMNSTELDPGLKGPHRCGVCRRVYINKDTLEEHKKIHHKKKILDLKCKICDKQLKQMSRFTIHMRNHTGERPFECETCGKSFKTSSCLGRHKINHTLEKSFKCEVCGNDFYLSTQLKKHMRVHSTDHPFECTICGKSYKAKASLQMHGHSHSDKRLFRCDICGLSYKTPNSLATHRKIHTLVPTGSLQCDVCKKILSTANILKRHQKLHLGQNRQYTDQRPYKCGTCGKTFASQRNWSRHMREHNTSSNS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -