Wsmi013338.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- su(Hw)
- Assembly
- GCA_029784165.1
- Location
- CM056644.1:163077397-163088605[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 4.7 5.1e+02 3.1 0.1 2 22 866 886 866 886 0.92 2 13 0.00031 0.033 16.3 0.4 2 23 942 964 941 964 0.95 3 13 0.022 2.4 10.5 0.3 1 23 970 992 970 992 0.97 4 13 0.00033 0.036 16.2 3.7 1 21 998 1018 998 1019 0.95 5 13 3.5e-06 0.00038 22.4 0.2 2 23 1031 1052 1030 1052 0.96 6 13 1.5e-07 1.6e-05 26.7 0.4 1 23 1062 1084 1062 1084 0.99 7 13 2.5e-05 0.0027 19.8 0.6 1 23 1090 1112 1090 1112 0.98 8 13 0.00043 0.047 15.9 1.0 1 23 1118 1140 1118 1140 0.99 9 13 0.0001 0.011 17.8 3.8 1 23 1146 1168 1146 1168 0.95 10 13 0.0026 0.29 13.4 0.6 1 23 1174 1197 1174 1197 0.97 11 13 2.1e-05 0.0023 20.0 0.3 3 23 1205 1225 1204 1225 0.97 12 13 2.7e-06 0.0003 22.8 1.1 1 23 1231 1253 1231 1253 0.98 13 13 0.016 1.8 10.9 4.1 3 23 1261 1282 1260 1282 0.97
Sequence Information
- Coding Sequence
- ATGGTTTTTAGAAGATGTGAGTTCCCGGATTGCACAAGTGCTGCTTCCGGTCCAAGTTCGAAAACGTTTCACAAAGTTCTGGTGAAAAACAGTTCTCGAGATCTTGAGAAATGGAAAGCAGCTTGCGGTACTGAGGAATTTTCGATTGATTCTGTTATTTGCGGTGATCACTTTCAGGATGAGGACTTCATCAATCCTCTTTGCAAAAGTCAGGGACTACGACCGACAGCCGTCCCCTTGTCAAACCGAAATATCGAAAGCCAAATGTCACCTGATGATGGCATTGGCTCGATGGTGTTTGATACCTCAATCAGGGAGCGGGATGCAGAAGGAGAAACAGATTTAGTTCTAGATACATCGATGGATGTGGTAGAAGAAGTTGTAATGAACGacattaaaaagaACTATGAGCACGACTACTGCTTCGATCCCAACAGGTATATTTTGATGGCAGATCGATTACTCGAGCTGGAGGCGGAAAATCTAAAACTAAAGCGCGAACTTAGAAAGAATAAACAATGTTTGTGCAAGAAAAATGCCTCCATTCAGAAACTTCGACTGGAGTTGgctaaaatcaaatcaaaactaACGTTTCCAACTAACCCACTTCAAGATCCATTTCTTGGTGAGTTGCAAAGAAATAAGAATAGGAAGTGTCGGGGAGCCCGATCCTCGGACTCTATGAAGAACATGGCTCTTGTTTTGCAGTATTGCTCTACAAAAGCTTATCGACAGATGCGACAGTTCATGGCACTGCCGAGTTTGAGTACAGTGCGCGCATGGTTGGGGCGCATCCGAGAATTTTTCTCGACAACCATACTTcagttgttgaagataaagTCATCGACTATGACAGAGGACGAAAAACTCGCCACTCTCACTATAGACGAAATGGCTTTCGCTGAAAGAGTGACGTACGTTTATAAAGCGAAGCCAGACTACTTTAGTGGATTCCCTACGAAACTGCCTGgtcaaaaaacaacaaacacAAAGGTCAGAGCGAAATCTGTTTTAACCCTCATGATAAAAACCATTAAGACTGGATTCAAGCAAGCCATTGGCTATTTTTTttgccatggcctcactgcagCTCAACTGCGACCCGTTGTGGACAAGGCGTTGGATCTTATATTGGAGGCTGGGTTAATTTCAAAAGTAATAACCTGCGACCAGAACAGTGTGAATCGGAATTTATTCTCTAAAGAATATGAAGCTACAGTGGAGGCCCCATATTTTGATATGCAAGTCGGTGAAGGGACAAACCATGTCTATTGCATGTTTGATGCCCCTCATCTTATCAAATCATGCAGAAACAATCTTCTTAAACATGATGCAGTTTGGGATGGCCAACTATGCAGTTTCGAGGATATAGTCCAACTTTACTGGGAAGACGTGAAAAACGTACCACGGGTCGTACCTGGGTTAACCTATGAGCACATACGCCTTTCACAGTTCAGTGAAATGAATGTTGGCTTGGCTGTACAAGCGCTGAGCCATTCCGTCGTAGCTGGTCTAAAGGACTATGTAAGAACTGGGAAACTTCAGAAAAGAGCTTTGAATACGGCTAAGTTTTGCGAGGTATTCGATGTATTGTTCGACATTGCAAACACTTCAAACCTTAAAGAGAAAAAAGAACTCAAGCGACCACTAAAAACAGGCTCTCCGAACTGGCCGTTTCTCGATGAGGTATCCCGAAAGCTTAAAAAATTATACTTCGTTGGAAAACAAGAGGAAACGCTTTGTGTGGATCCTGCAAAGGATTGTCTTGAGCATTTTTTCTCGGTAATTCGATGGAGAAATGGTAATAACACACACCCGGATGCCTCTCAATTTTCGTCGACGTATAAAGCCGTCGTGGTACATCAACTATTGGTACCTAAAAAAGTTGGCAACGTGCAAGCTGACGTAAGCATGCACATATTATCTAGTGATGAATTGCGAAAACTAAATGTAGTGCAACAGAAACGGGTTTCTCGAAGCGATTATGAGGAAGTAGAAACGCTACGTGATTTAAAATATGATACGTTCGACGAAAACCAACTTTCCAGTATTCACTGGACTACAGGCTGGGCCTGTAGCAAGTTGAGTCACTCTGAATgcattaacagaatttattCTGAAAGCGAACAAATCCCTGAAGCACACAAATCTCTGGCTGGATATAAGATGTACAATGATCATGTAAAAATTCAAACACCTGGTGAGAAGATATTCACATATTGTCAAGGAATTTGTAGCATATTCCAGCAAAATTTTGAGCTCTTACTGGAGATTGATACAGTAGGGGTGAAGGAGGAACTATTTGATATTGTTAAGACTCGCTTCGACTATCACACAGTAGCGTCCGATGACGTAGATGAAAAAATGGAAAGCAAACGGCACCAAATGTCTCAAAAGTCACGCGTTCGTCCCAAGGGCGAGAAATTTCGCTTGACCGTACCGCTCGACGCGGATCCGGAAACGGATGTGGAGCTGGTTCCAGTAGATGAAAACACACAGGATTCGGAAGATTTTGCTACTACGGAAGATAATGCTGAGCCAGACCTGGTGCAAACTCAGGACGGCCGGTTGATCATCGAGATGAAAACGAACCGGACATGTCCAGTATGCAAGTCAAATTTTCCAACAGTTAAGATTCTGGAGAAACACCAGTTAACTTGCACCAATAAAGAGGACGAGTTTAAAGATGTGTTACAAAAAGAGAAAGCTGCAGCAATGACCGCTCAACCAGGCGAAGAGTTTTTCAAGTACTGCAATCCGAGTCCCGAGAACCCTTGTTACTGTTGCGGTGAGGACAAATCGACGGCCCATGTTGGCCATATGCAGTGCAAATATTGTCCAAAATCATTTAAAGCCTTCGaatatctagagaaacatttggCTTCCGTACATGCCGAGAGTGCAGAATTTGCTTGTCCACAATGCAATGCACAGTGTTCGACAGCAACGGTTTTGCAGGAGCACCTAGAGACCCACAGCGAAGGAAAACCATTCTCGTGCCTGAAGTGTGGCAAAGATTTTACACGTAAATATCACCTGGATCGTCACTTGAATCACTCAAACTGCGGTAATATCCCGAAGCAGACATTACCCTGCGAAGTGTGCGGTAAAGAATTTACACGTTTGGACAATTTGCGAGAACACCTTCGTTTTCATATGGGACAAGCCTCGCGAAAACGTGATTACCAGTGTCCATATTGCCCGAAATCGTTCTACGGGTCATCACTGTTAAACATCCACATTCGTACCCACACCGGCGAAAAGCCTTTTCCGTGTGATCTTTGTACCAAATCATTCCCATCTACGGGAGCGTTAAGAAAACATCGAAGATCGCACACCGGGGAGCGTCCGTACCGTTGTGATCAGTGTTCTGCTACGTTTGCTGCCCGAGAAACTTTGAACAGACATCGGAAAACTCATACAGGTGAAAAGCCACATCACTGCACGATTTGTGATAAACGATTCATCCAGGCGACGCAGCTCCGTGCGCACATGTTCAACCACACCGGACAAAACGGTTTCCAGTGCGAGCAGTGCAATGTCTCTTTCGGCCGCAAAACGCGACTTGATGAGCACATTCGCTACGTGCACAACAAGAAAAAGCAGAATTCCTGCGGAGTTTGCAACAAAGGATTTGTGCGTTTGGAAGATCTCAAGCGCCACATGGATACTCACAACACGGAAAAAAATTTTGCTTGCAATCAATGTGGCAAACGATTTTCGTCTAAAGCCGCAATGAAACTTCACCAAAGAACCCATTCTGTTGAAGACCCTGTCGACTGTGATATCTGTGGCCACCAGTTTCTGCGACAGGACTGTTTGCTTCGTCACATGAGATCGAAACATCGAGATAAGCAGCCTATAAAATTGGAAGAATTGAAAGTGGAAGAACCTCCGCTGCTCCATAAGGCTCAGGAAGTACTGGAAATTGGTGGAGAAGTATACCAAATAACCCCAGTTGATAATGTTCAAATAGTAAACATTACTTCACCGTCACCGTCAACCACAACGGAGTTGACCACCGACAATCGACTGAAAATTTTAGAGGTAGTCAAAATCATGCCGCTGGAACCATTTTTGGTTCCACAAACTACGAACACTAAAACTGAAGTAAAACACCAGCCTCATACGGTGTCGAAACCTTCCCAAAAACCGCTGCCGGCAGCTGTGAAGAAACCTCAAAACAATCCAATCTCATCAGCGAATAAAGTAAATCCCGAGCGAAAGAAGCGCACACGAGCTTTGAACCAGAACCAGAGCAATGCACAGCCCAAAAGCAAGATCAAGATCGAACAACAGGACGACTCCATGCCAATCTTTCTCAGTGATGACGTATTGAAGGATAAAATCGGAGAACTTCTTCGCTTGTTGATTGATGAGGACGTGCTTACAGAATTTGGATGGCCGACGGCACCGGTAGACGAGCTGCTTGGCAACGTAATCACCCGGTGCGGCTCTAAACCGTCCAGCGACGCCGATAGTGGTGACTGTACGACAAGGCTGcgggaaaatacaaaaattttgttttcacttACCATGGATGATGATAACATAAAAACATTGCTCAACAATCACACCGTCGACGAGGTGATCATGAATGTCCTCAAAAATAAGTGA
- Protein Sequence
- MVFRRCEFPDCTSAASGPSSKTFHKVLVKNSSRDLEKWKAACGTEEFSIDSVICGDHFQDEDFINPLCKSQGLRPTAVPLSNRNIESQMSPDDGIGSMVFDTSIRERDAEGETDLVLDTSMDVVEEVVMNDIKKNYEHDYCFDPNRYILMADRLLELEAENLKLKRELRKNKQCLCKKNASIQKLRLELAKIKSKLTFPTNPLQDPFLGELQRNKNRKCRGARSSDSMKNMALVLQYCSTKAYRQMRQFMALPSLSTVRAWLGRIREFFSTTILQLLKIKSSTMTEDEKLATLTIDEMAFAERVTYVYKAKPDYFSGFPTKLPGQKTTNTKVRAKSVLTLMIKTIKTGFKQAIGYFFCHGLTAAQLRPVVDKALDLILEAGLISKVITCDQNSVNRNLFSKEYEATVEAPYFDMQVGEGTNHVYCMFDAPHLIKSCRNNLLKHDAVWDGQLCSFEDIVQLYWEDVKNVPRVVPGLTYEHIRLSQFSEMNVGLAVQALSHSVVAGLKDYVRTGKLQKRALNTAKFCEVFDVLFDIANTSNLKEKKELKRPLKTGSPNWPFLDEVSRKLKKLYFVGKQEETLCVDPAKDCLEHFFSVIRWRNGNNTHPDASQFSSTYKAVVVHQLLVPKKVGNVQADVSMHILSSDELRKLNVVQQKRVSRSDYEEVETLRDLKYDTFDENQLSSIHWTTGWACSKLSHSECINRIYSESEQIPEAHKSLAGYKMYNDHVKIQTPGEKIFTYCQGICSIFQQNFELLLEIDTVGVKEELFDIVKTRFDYHTVASDDVDEKMESKRHQMSQKSRVRPKGEKFRLTVPLDADPETDVELVPVDENTQDSEDFATTEDNAEPDLVQTQDGRLIIEMKTNRTCPVCKSNFPTVKILEKHQLTCTNKEDEFKDVLQKEKAAAMTAQPGEEFFKYCNPSPENPCYCCGEDKSTAHVGHMQCKYCPKSFKAFEYLEKHLASVHAESAEFACPQCNAQCSTATVLQEHLETHSEGKPFSCLKCGKDFTRKYHLDRHLNHSNCGNIPKQTLPCEVCGKEFTRLDNLREHLRFHMGQASRKRDYQCPYCPKSFYGSSLLNIHIRTHTGEKPFPCDLCTKSFPSTGALRKHRRSHTGERPYRCDQCSATFAARETLNRHRKTHTGEKPHHCTICDKRFIQATQLRAHMFNHTGQNGFQCEQCNVSFGRKTRLDEHIRYVHNKKKQNSCGVCNKGFVRLEDLKRHMDTHNTEKNFACNQCGKRFSSKAAMKLHQRTHSVEDPVDCDICGHQFLRQDCLLRHMRSKHRDKQPIKLEELKVEEPPLLHKAQEVLEIGGEVYQITPVDNVQIVNITSPSPSTTTELTTDNRLKILEVVKIMPLEPFLVPQTTNTKTEVKHQPHTVSKPSQKPLPAAVKKPQNNPISSANKVNPERKKRTRALNQNQSNAQPKSKIKIEQQDDSMPIFLSDDVLKDKIGELLRLLIDEDVLTEFGWPTAPVDELLGNVITRCGSKPSSDADSGDCTTRLRENTKILFSLTMDDDNIKTLLNNHTVDEVIMNVLKNK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -