Basic Information

Insect: Wyeomyia smithii
Gene Symbol: -
Assembly: GCA_029784165.1
Location: CM056645.1:246982465-246987271[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.019 2.1 10.7 2.1 1 23 243 266 243 266 0.90

2 23 0.00058 0.063 15.4 5.6 1 23 272 294 272 294 0.98

3 23 0.059 6.5 9.1 1.2 1 23 351 373 351 373 0.98

4 23 0.00042 0.046 15.9 3.0 1 23 380 402 380 402 0.98

5 23 0.00043 0.047 15.8 0.4 1 23 414 437 414 437 0.97

6 23 2.1e-05 0.0023 20.0 0.8 1 23 464 486 464 486 0.97

7 23 0.27 30 7.0 1.1 1 23 500 522 500 522 0.97

8 23 0.013 1.4 11.2 4.2 2 23 568 589 568 590 0.94

9 23 0.0013 0.14 14.4 2.4 1 23 596 618 596 618 0.98

10 23 0.0046 0.51 12.6 2.9 1 23 650 672 650 672 0.99

11 23 0.047 5.2 9.4 0.2 1 23 746 768 746 768 0.98

12 23 0.0053 0.57 12.4 5.9 1 23 798 820 798 821 0.95

13 23 0.00038 0.041 16.0 6.1 1 23 827 849 827 849 0.98

14 23 0.0054 0.59 12.4 0.2 2 23 917 938 916 938 0.98

15 23 0.23 25 7.3 7.1 2 23 963 984 963 985 0.95

16 23 0.0038 0.42 12.9 2.2 1 23 991 1014 991 1014 0.94

17 23 1.4e-05 0.0015 20.6 1.3 1 23 1045 1067 1045 1067 0.99

18 23 0.004 0.44 12.8 2.0 2 23 1089 1110 1088 1110 0.97

19 23 0.079 8.7 8.7 4.0 2 23 1218 1239 1217 1240 0.94

20 23 0.00021 0.023 16.8 2.7 1 23 1246 1269 1246 1269 0.97

21 23 0.0053 0.58 12.4 2.5 1 23 1287 1310 1287 1310 0.96

22 23 0.11 12 8.3 0.4 1 20 1316 1335 1316 1337 0.94

23 23 0.1 11 8.4 1.9 1 20 1363 1382 1363 1384 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.019	2.1	10.7	2.1	1	23	243	266	243	266	0.90
2	23	0.00058	0.063	15.4	5.6	1	23	272	294	272	294	0.98
3	23	0.059	6.5	9.1	1.2	1	23	351	373	351	373	0.98
4	23	0.00042	0.046	15.9	3.0	1	23	380	402	380	402	0.98
5	23	0.00043	0.047	15.8	0.4	1	23	414	437	414	437	0.97
6	23	2.1e-05	0.0023	20.0	0.8	1	23	464	486	464	486	0.97
7	23	0.27	30	7.0	1.1	1	23	500	522	500	522	0.97
8	23	0.013	1.4	11.2	4.2	2	23	568	589	568	590	0.94
9	23	0.0013	0.14	14.4	2.4	1	23	596	618	596	618	0.98
10	23	0.0046	0.51	12.6	2.9	1	23	650	672	650	672	0.99
11	23	0.047	5.2	9.4	0.2	1	23	746	768	746	768	0.98
12	23	0.0053	0.57	12.4	5.9	1	23	798	820	798	821	0.95
13	23	0.00038	0.041	16.0	6.1	1	23	827	849	827	849	0.98
14	23	0.0054	0.59	12.4	0.2	2	23	917	938	916	938	0.98
15	23	0.23	25	7.3	7.1	2	23	963	984	963	985	0.95
16	23	0.0038	0.42	12.9	2.2	1	23	991	1014	991	1014	0.94
17	23	1.4e-05	0.0015	20.6	1.3	1	23	1045	1067	1045	1067	0.99
18	23	0.004	0.44	12.8	2.0	2	23	1089	1110	1088	1110	0.97
19	23	0.079	8.7	8.7	4.0	2	23	1218	1239	1217	1240	0.94
20	23	0.00021	0.023	16.8	2.7	1	23	1246	1269	1246	1269	0.97
21	23	0.0053	0.58	12.4	2.5	1	23	1287	1310	1287	1310	0.96
22	23	0.11	12	8.3	0.4	1	20	1316	1335	1316	1337	0.94
23	23	0.1	11	8.4	1.9	1	20	1363	1382	1363	1384	0.89

Sequence Information

Coding Sequence: ATGGAAAATCGCGAACCGATAATATCCGCCAGCTCCACCATCCCTGCCATCGCTGCTAGCAGTAGCAGCACTAATAATGCAACAAACATGCCAGAGGCTACTGGGAACGGTAACAGCAACGGAGAAACTTCATTAGAACCCAGAGGAGGCACCGTTCTGCCAGTGATAAATACATTGTGCAGAATATGCATGTACGACACCCGCACAGAGGGAGGAAGATTATTAGAATCTCTTTCCCGCACGATGATCGAATCAAAAACTTTGTACTCTATGCTTGTTACTGTATGTTCGCCACTGGCCCAGACCAATAACGAGGGAATGCCGGATAAAATATGTTCATGGTGCAAAGCTAGGCTCGTGCAAGCGTATAAATTATATGAGACGTGTATCAAGAGTGACGACAAAATCCGGAAGCTACTACAAATGCAGGCCGGAGGAGTACTTATAAAACAAGAGATCATTGACGATGAAGACGACGACGACTTCCCGAATGCGGAAATGTTCTGCGACGCTCAGGTTAAGCGAGAAGATCATTACGATCAAGATTATCTGTTTGACGAACATTTTTATGAAGCGGCTTTATCGAATCTTAGAATTCAATCAGTTCACAACGGACCGGAAGTGCTGGTGCAGCTCCAGGAGCACAACTATCCAGCAGATTTTGGGGCAATTTTATCAAAACCTATTTTCGAATGTGAGAAATTCGTTAAAGTAACCCCAAAAGGTCACGTCTGCTTGCTTTGTGGCAAAGATTTCAAGTATTTCAGTTACTTTAAACAACACGCATTAGCCCAACATGATCCGGAAAAACCGCACAAGTGTGAGAAATGCAAGTATACGTTTAAGAGTGAACAGCGATTGTTTATTCATATGCGTACGCACATTGAAGCTGAAATACAACCTGTCACTGCAACAGAGCAAGCAAAATTTCAGGACTTGTCGCCAGAAGATGAACCGGAACCAGATCAGGATCAGCTTGATGATTCAATCGCTGAAGAGGACAGTCCAGATTTGAGCATATCCATTAATCCGGACACAGGAGAAAAGGTGTATACATGTTTAATTTGTCAGAAACAATTGTCCACATTTCCGTTGTACAACCGCCATCGAACGGTTCACACTGTCCGGGGACGACCTTTCGAATGTGATATTTGTCACTACCGGTTTGCAATGAAATTTAGCTACAATGCTCATATGCAACGCCATGAACAGGGCAAAGATCCAGCTCAGccagccactttcaaatgtttgGAATGCGATGAAGTCTTTTTCAggagaaaattattaaacctgcATGTAGCCACCGAACATGAAAGAACTCTGGTGCCACTCAATAAAACCGCTCCTGCTGCAATTCTAACAAGTAATATCTCTGACGGTCGGCATGGCCACTCTTGTCCATTGTGTCCGGAAACGTTCAATCGAGAATCAGTGCTAAATAATCACATGAAAATGCACGAACTCGAAGCTGCCCAACTGAAACATTCGGAAGTTTGTTTTGTGTGCACCGTCTGTGGTTTGGAATGTGAAACACGTAAAATTTTCGAAAGCCACATAACAACTCATGGTGACGTTCAACTACCGACTGCTGTCGGACAATCCCAGGCGGAGGCCGATCTCAGCGATGAAGAACATAACACCCAAAACGGTGAGGACTCTACCGCTGCCTCCAGTGCTAAGCCGGACATGAAAATAGGGGCAAAGTGCGATCTTTGCTCCAAAACATTCCCGTATGCGTGCAACCTAAAGCAACACAAAGTTATCCACCACTCCGAACTGAAACCACACGAATGCTCTATCTGCTTTTATCGCTTCGAATATGAGGGTACTCTGCTCCGGCATATGCAAAAACATTCCAAGCCGGAGTCTAGCGTTCCTTCAGTCACCGCACAGGTCCCAGCCGTGAGTGAAGATACCATTGTCGCTCCACCGGGAGCTACGCTTATTTACAAGTGCAAATTGTGCTCCGCTCGCTTTCAGAAACAGAAATCGATGACTTGGCATCTGAAGACGCACCGGTCGATTGTGGCCAGTGAAGGTAATGCCTCTGTCATACATCAGCTGGAGCAAAGTCTTCTGCAAGCGGCAGCATCTACCTCGCAGCTACCGAGAACGTCATCTCCGGGCAACTGTTCAAGCCCGTCACCGGCGGTTCGTGCCAAGTCCCCGAGTTCGCACACATCACCGACATCCACAGACAAACCGTCGGCGGCGGCCAGCAGCACTCCAAAGATGTACAAATGCGGTTACTGTCCGCAGAACCTAGATTCGGAGGATGCCTACTTCCAGCATCTTAAGGGTCACCGCGTTCGACCAAACGATTCCCTTCCAACGGAAGGCGAAAGTCCACCGGCGAAGAAAAAACGTTCTTGGATTCGTTCTGGAGACCATCATCGGTGCAATCTGTGCCTGAAACAGTTTACCTTTCGCAGTCAACTCCAACAGCACATCTCCCTTCATCACCAGCCGGGAAAACCGTACGAATGCCAGAAGTGTCATTACAGTTTCGTGCATAAGTTGAATCTCAAACGGCACGAGTTGACCCATTTGGAGGAGGAAAGACTGGCCAGCGAGGATGATCCGACGATTCAGTTGCTGGAGGATGAGGGCTTCAATGCTGAGCTGGAGGACATGGTCGAACCGGTGCTGGAAGAAAAGACTTCAGCTGACGAAGGTAACGATCCTCCGTCATCTGGTGAAGGAGGAACAACACCTTCAACTGCAGCGGCAGGACcaccaaagaaaaacaaatgcgTCGTCTGTGCCACCGTATTCCAGCGGGAGGATCAACTTATTGAGCACCTGAAGACACACATCGAGCGCATTAAGGTGACCAAGCAAGAAACACAAACCGcaaaaaaaatactctccgaTGATAACGACCGAAAATGCAAGCTGTGCATGAAGGTATTCAAGTTCTCCTGCCAGCTGAAGCAGCACGTGCAGATGCATCACGCCAAAGAGAAGCCTTTCGAATGTAACATCTGCAAatatcGGTTTGAATTCAAAGGCCACATGATCCGTCATAAAGCTATAAACCACGCTGATGAAGTGGCAGCGGAGGAAGCGGAAATGGATGAATTGCCATCAAAAATCACCACACCGACTGTGAACCCAGATGGTTCTGAAGTGTACCAGTGTCCGGTTTGTCCGATGCATTTCGTGAAGCAGCGTTCGCTCACGTGGCACCTCAAAACTCACTCCACACGACGATCCCGACATGGTGACGATGGAGGACCTTCCACATCCGGTGGAGAAGTCATGCAATGTCGCTTTTGTTCACGAACTTTCCATGATGTGTACGAACTGAAGGCCCATATGGTTACACACATTGGCAGCGGGGCTGGCGGCTCGACATCACTGGCCACTATGCCTGAGGCAGAACATTCGCTTTTCGGTTCCGGACTGGACATGATGCTTCAAGATTTTCCTGATACTATGGAAAATCACGGCACTGATCCATTGTTCGACGAGTCCAACTTGGAGTTGGTACTGGAGGATGGATTCGATAGTGACGATCTCTCGTTTAATATGAATTACCATGAAACGCCGCCTCTTCCACCAGCCAAAAGAAGTCTTCCAGCCAGTGAAAACTCGATTTACGACGTAGCAGAACCTGGTGCGTCAACAACACCGGCGAAAGGAAAAATTGTCTGCGAGTTGTGCAAGAAAGATTTCTTGTACTCGTGTAATTTGAAACAGCACATGCAACTTCATCACGCCAAGGACAAACCATTCGAATGTAAAATTTGCTTCTACCGGTTTGAGTATAGTGGCCACCTGGTGCGCCATATTCGACAGAATCACGACAAAAGTCAAGCTGATGAGGCAGCTGGCGATACCACAGTGGAGAAAAACTTTGTTTGCACTTTCTGTTCGGAGctctttgaacaaaaatCCCAGTTAAACACACATCTGCACATCTATCACAAAGGAGAGAAACAATTCAAATGCGACTTCTGTCCGGCCTCCTTCGCCTACAAAAAGGCATTCGATTCTCACCGGGAAGAGTGCAGATTAAACAAGCGATTAGACTCAGCCACGGGAACCTCGGCATCATCCAGTAAGACTTCTGGTGTAACCAGCTTCTCGTGTAATTTATGTAAGAAGGTCTTCAGTTCCGCTCAGAAGGTGGATAACCATGTTTGCTTTCAATAG
Protein Sequence: MENREPIISASSTIPAIAASSSSTNNATNMPEATGNGNSNGETSLEPRGGTVLPVINTLCRICMYDTRTEGGRLLESLSRTMIESKTLYSMLVTVCSPLAQTNNEGMPDKICSWCKARLVQAYKLYETCIKSDDKIRKLLQMQAGGVLIKQEIIDDEDDDDFPNAEMFCDAQVKREDHYDQDYLFDEHFYEAALSNLRIQSVHNGPEVLVQLQEHNYPADFGAILSKPIFECEKFVKVTPKGHVCLLCGKDFKYFSYFKQHALAQHDPEKPHKCEKCKYTFKSEQRLFIHMRTHIEAEIQPVTATEQAKFQDLSPEDEPEPDQDQLDDSIAEEDSPDLSISINPDTGEKVYTCLICQKQLSTFPLYNRHRTVHTVRGRPFECDICHYRFAMKFSYNAHMQRHEQGKDPAQPATFKCLECDEVFFRRKLLNLHVATEHERTLVPLNKTAPAAILTSNISDGRHGHSCPLCPETFNRESVLNNHMKMHELEAAQLKHSEVCFVCTVCGLECETRKIFESHITTHGDVQLPTAVGQSQAEADLSDEEHNTQNGEDSTAASSAKPDMKIGAKCDLCSKTFPYACNLKQHKVIHHSELKPHECSICFYRFEYEGTLLRHMQKHSKPESSVPSVTAQVPAVSEDTIVAPPGATLIYKCKLCSARFQKQKSMTWHLKTHRSIVASEGNASVIHQLEQSLLQAAASTSQLPRTSSPGNCSSPSPAVRAKSPSSHTSPTSTDKPSAAASSTPKMYKCGYCPQNLDSEDAYFQHLKGHRVRPNDSLPTEGESPPAKKKRSWIRSGDHHRCNLCLKQFTFRSQLQQHISLHHQPGKPYECQKCHYSFVHKLNLKRHELTHLEEERLASEDDPTIQLLEDEGFNAELEDMVEPVLEEKTSADEGNDPPSSGEGGTTPSTAAAGPPKKNKCVVCATVFQREDQLIEHLKTHIERIKVTKQETQTAKKILSDDNDRKCKLCMKVFKFSCQLKQHVQMHHAKEKPFECNICKYRFEFKGHMIRHKAINHADEVAAEEAEMDELPSKITTPTVNPDGSEVYQCPVCPMHFVKQRSLTWHLKTHSTRRSRHGDDGGPSTSGGEVMQCRFCSRTFHDVYELKAHMVTHIGSGAGGSTSLATMPEAEHSLFGSGLDMMLQDFPDTMENHGTDPLFDESNLELVLEDGFDSDDLSFNMNYHETPPLPPAKRSLPASENSIYDVAEPGASTTPAKGKIVCELCKKDFLYSCNLKQHMQLHHAKDKPFECKICFYRFEYSGHLVRHIRQNHDKSQADEAAGDTTVEKNFVCTFCSELFEQKSQLNTHLHIYHKGEKQFKCDFCPASFAYKKAFDSHREECRLNKRLDSATGTSASSSKTSGVTSFSCNLCKKVFSSAQKVDNHVCFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -