Wsmi001735.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- -
- Assembly
- GCA_029784165.1
- Location
- CM056644.1:18537691-18539687[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 3.4e-05 0.0038 19.3 1.6 2 23 95 116 94 116 0.96 2 15 0.0007 0.076 15.2 1.2 1 23 122 144 122 144 0.96 3 15 7.2e-06 0.00079 21.4 1.3 1 23 150 172 150 172 0.98 4 15 0.00012 0.013 17.6 6.1 1 23 178 200 178 200 0.98 5 15 5.2e-05 0.0057 18.7 0.3 1 23 206 228 206 228 0.98 6 15 0.0034 0.38 13.0 1.7 1 23 256 278 256 278 0.97 7 15 6.9 7.5e+02 2.6 0.7 2 20 296 314 295 317 0.84 8 15 1.3e-05 0.0014 20.6 0.7 1 23 323 345 323 345 0.99 9 15 0.00025 0.027 16.6 1.0 2 23 352 373 351 373 0.96 10 15 1e-05 0.0011 21.0 1.2 1 23 379 401 379 401 0.99 11 15 1.8e-05 0.0019 20.2 1.4 2 23 406 427 405 427 0.98 12 15 0.0018 0.19 13.9 0.7 2 23 434 455 433 456 0.94 13 15 0.00027 0.029 16.5 1.5 1 23 481 503 481 503 0.97 14 15 8.4e-07 9.2e-05 24.4 2.4 1 23 509 531 509 531 0.98 15 15 0.0023 0.25 13.6 2.5 1 23 537 561 537 561 0.92
Sequence Information
- Coding Sequence
- ATGGAGGAAGTCAGTCGAAAACAGGTGGAAGGACTTATTCCAACGATAAAGGTAGAAGAGCTTATAATATCGGACGACGTGTCCAGGGAAGGAGAAATGCCACTTTCTAGCAGCAATCGATGCTCTAGTGAGCCGATGGTAAAGATCGCCCTGGACGGCGGTTCACCTGATGTGAAACAAGAACCTGGGACGGACATCACGGTTGAAGTTGAGGTTACAGCAGCTGGTAGAAAAAATAAAGCTGCTAGCTCCAGCAGCTCAAAAAAGGACAACACCGCTGTTGTTTGTGACTTCTGCAACAAGAAATTCAGCACAAAATACTACTTGAAGGAACATAGAACAATTCACACCGAGGAACGACCTTTCTCGTGCGATATCTGCGGCAAAACATACCGCACAGCTGGGATTTTGCACAAACATAAGAGTATCCACACAGAGGGTGGGGATTTTGAGTGTGACATATGCAAGCGACATTTTACCGTAAAAACAAATTTGGTGGCTCACATGAAAGCTCACCGCCCAGATTGCCCACATAAATGTTTGATTTGCGATAGAACATTCCGATCGAATTGTCGTCTCGTACAACATATGCGCACTCACACCGGTGAGCGACCCTTCAAATGCGACATCTGTGACGCATCATACAACAGACGTTATCCTCTGAACTTACATATGGAGAGCCACAAGGTCGGGCCCACCCCAGACAACAACGAGGGTTTAAAGCCGAAACGGACAAAGAACAGCCGAAACGATGGTTCACAGAAATACATCTGCGACATATGCGGTAAACAGTATAAAATAATGAAATCACTCCACTTACATCAGAAGCTTCATCAAAGCACCACTGTGAGGCCTGAGAAAAAAACCCAAAACCAACTGGTGCTCGAGTGTGCGGTTTGTGGAAAACCAAATCTCAGTAGAACAATGCTCAGAAGACACATGATTTGTCACATTAAAGAACGTGCTTTTAAATGCGATATTTGCGGTTCATCATATAAGACAGCTCGAGATGTAAAAGTACACCAGAGAACGCACTCCTCCGAGAGACCGTGTCAATGCGAAATTTGCGGAAAAAGGTTTCTTTTTCCTTCCGCATTGAAGACCCACTTGATGTGGCACAATGAGGAACGGCCTTTCAAGTGCGATATTTGCGGTCAATCTTTGAGGACAGAATATAATCTAAGACTTCATAAACAAACGCATATACGTGAAAATAAATGTTCGGTTTGTGGAAAAAAATTCCGTTTTTCCCGATTGCTCGTACAACACATGCTATCTCATCCCGATCAGCAATTGTGGAAATGTGATATTTGCAGTTCAGTATTTGATACAAATGATTTGTTGAATGTGCACAAACAAGAGCACCATCAGCCTAACAATGAAAGCATAACACCCGAGCATCTTGTGACGCCTGTGACTGCTCCTTCAgaagaacaaattttcaattgcaatatTTGCGGGTCATCGTATAAAACAGCTATTTACTTTAGAAAACATCAGGAAAGGCACAACTCGGAGAGTGCGTTTAAATGCGAAATTTGCGGTAAGGAATTTGCATTTTCCTACAATCTAAAGCAGCACATGCTTCACCATAATAATGAACGGCCCTACAAATGTGATATTTGTGTTTATACATGCAAGACAAAGGCTGCATTAAGGATGCACGAGAGATCACAGAAGCACCTGAAGCGACAATACAACACAAATGACGATGACGAGCAGAGTGACCAGGCCGATTCTCAGGGTGAAATTAACGTAGGAGAATTTGTTTCTTGTGTGAGTTTAACTGAATAG
- Protein Sequence
- MEEVSRKQVEGLIPTIKVEELIISDDVSREGEMPLSSSNRCSSEPMVKIALDGGSPDVKQEPGTDITVEVEVTAAGRKNKAASSSSSKKDNTAVVCDFCNKKFSTKYYLKEHRTIHTEERPFSCDICGKTYRTAGILHKHKSIHTEGGDFECDICKRHFTVKTNLVAHMKAHRPDCPHKCLICDRTFRSNCRLVQHMRTHTGERPFKCDICDASYNRRYPLNLHMESHKVGPTPDNNEGLKPKRTKNSRNDGSQKYICDICGKQYKIMKSLHLHQKLHQSTTVRPEKKTQNQLVLECAVCGKPNLSRTMLRRHMICHIKERAFKCDICGSSYKTARDVKVHQRTHSSERPCQCEICGKRFLFPSALKTHLMWHNEERPFKCDICGQSLRTEYNLRLHKQTHIRENKCSVCGKKFRFSRLLVQHMLSHPDQQLWKCDICSSVFDTNDLLNVHKQEHHQPNNESITPEHLVTPVTAPSEEQIFNCNICGSSYKTAIYFRKHQERHNSESAFKCEICGKEFAFSYNLKQHMLHHNNERPYKCDICVYTCKTKAALRMHERSQKHLKRQYNTNDDDEQSDQADSQGEINVGEFVSCVSLTE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -