Wsmi001771.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- -
- Assembly
- GCA_029784165.1
- Location
- CM056644.1:18753935-18756487[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.00049 0.053 15.7 3.2 1 23 88 110 88 110 0.98 2 17 0.019 2.1 10.7 0.4 1 23 116 139 116 139 0.94 3 17 0.00017 0.019 17.1 1.1 1 23 145 167 145 167 0.98 4 17 1.3e-06 0.00014 23.8 2.0 1 23 176 199 176 199 0.98 5 17 0.0001 0.011 17.8 2.5 1 23 209 231 209 231 0.99 6 17 0.032 3.5 10.0 0.7 1 23 237 259 237 259 0.95 7 17 0.0062 0.67 12.2 0.7 3 23 267 287 265 287 0.97 8 17 0.00042 0.046 15.9 2.7 1 20 293 312 293 315 0.92 9 17 0.0023 0.25 13.5 2.4 1 23 321 343 321 343 0.98 10 17 2.1e-05 0.0023 20.0 3.7 1 23 368 390 368 390 0.99 11 17 0.0026 0.28 13.4 1.2 1 20 396 415 396 418 0.96 12 17 2.6e-06 0.00028 22.9 1.2 1 23 424 447 424 447 0.97 13 17 0.014 1.5 11.1 1.0 2 23 466 487 465 487 0.96 14 17 0.00059 0.064 15.4 1.1 1 23 493 515 493 515 0.98 15 17 4.3e-05 0.0047 19.0 3.2 1 23 521 543 521 543 0.98 16 17 9.3e-06 0.001 21.1 4.2 1 23 549 572 549 572 0.98 17 17 5.6e-06 0.00061 21.8 0.8 1 23 597 619 597 619 0.97
Sequence Information
- Coding Sequence
- ATGgaagaaaataatcaaataaagaTCGAAGAGCTCATAATATTCGATTCTTTGCCCACGGAAGAGGATACTCTACTTGTTAAAAGGGATTGGTGTACCGATGACACAACTGTAACGAACACTCAGAAGGAAGGTTCAGTTGATGTGATACAAGAACATCTGAAAGAACTCACTGATGAAGTTGGGAGTACAGCAGTTTGTGAGTCAGCTCCTCGCTGCAGCAACTCGGACGGTTTAAACATACCCAATCAATGGAAAGAGTACGTTTGTGAATTCTGCAACAAAGAATGCAGTGGGAAACAGAACCTCCAGGACCATAAAAGAAGTCATAATAGACAACGTCTATTTGCCTGTGATATCTGCAATGGAACATTCAACACAGCCAGACGTTTGCAGTACCATAAGAGCATTCTACATACCGAAGACCAGTACTTCCAGTGTGACATATGTAAGCAacgttttttgcaaaaatcataTCTATTGGACCACATGAACATACACCGCACATATGGCAATGAGCGATCCTTTAAATGCGACACCTGCAACACATCATACAAAAGATCTCAAGATTTAAAGGCTCATATGCGGAAGGTTCACAAAGTCGTTAAGCAACCGCGGAAAAAGTACGTTTGCGAATACTGCAACAAggaactgagctcaaaacacAGCTTAGACGATCATAGAAGAACTCATACCGGGGAACGACCTTTTGCATGTGATAAGTGCAACGCAACATTTATCACGACACAACGTTTGCAGTACCATGAGAAAGCTCATACAAGCGTTCGGAATTTTGGGTGTGACATATGCAAGCGACGTTTTTATCTAAAACAAACTTTGTCGTCTCACATGGTTATACACCGCTCAGATTGTCCACATAAATGCCCGTTTTGCGATAAAACATTCGCAAGTGGTGCTCATCTCAAGCAACATCTGCCCAAACACAGCGATGCGCGAGAATTTAAATGCGACCACTGTATGGCGTTTTATAAGAGACGTGATGCTCTAGAAAAGCACATGGAGAACCATGAGCTCTATCCCTTCTCAGGCAGCTTCAAAAGTATGCCGCGATTTGATAGTACTCATACAAGGCACCGGAAGTTCAAGTGCGACACATGTGAGCAACGGTTTTCGATGAAATCACATCTTTTGTCACACATGAAAATCCACCGCACAGATTGCCCGCATAAGTGCTCTATTTGTGATGCAAGATTCTCAGATGTCGTTCTCCTGGAAAATCATATGGTCTGTCACAGTGATGAGCGACCCTTCAAATGCGAAATTTGTGGTAGATCATACAAAAGACTTAAAGCTTTACAGCGTCACACCAGCAAAGTTCACCGTCCCCCAAGCTCTTCGGGCGAACCGAAGGACTTCGCCGGAAGGCGACGTTTAGAATGTGATATTTGTAGCGAAATATTTTACTCAACTACACGTTTGCATTACCATATGAGGGCTCATACAGGAGTCCCGAGTTTCGAGTGTGACATATGCGAACGACGCTTCGTTTTGAAATCTTACCTACGGTTTCACATGAAAATACACCTCACCGATTGCCCACATACGTGCCAGATTTGCAATAAAAAGTTCTCAACTAATCTTAAACTCCAAGATCATATGGTTACTCACACCGATGAACGACCCTTCAAATGTGACATATGCGACAGATCCTTCAAGGGATCTAATCATGTAAAGCATCATATGAGAATGATCCACAAGGTCGATCTCCCTCGAAGCGACAGGGAAAATTTGAAGCCAAACCAGACTGGTAACAGCCTAAGCGATGTATACAGCTGCGACGTATGCGGCAAACAGTACAAACAAAGAAGTTCACTTCGCATACATCAGGATCTTCATAAGATCGCCACAACCGTGACAGCGTCCCCACGCATGCTTAAACATTTCGGAAATGTTTCGTGA
- Protein Sequence
- MEENNQIKIEELIIFDSLPTEEDTLLVKRDWCTDDTTVTNTQKEGSVDVIQEHLKELTDEVGSTAVCESAPRCSNSDGLNIPNQWKEYVCEFCNKECSGKQNLQDHKRSHNRQRLFACDICNGTFNTARRLQYHKSILHTEDQYFQCDICKQRFLQKSYLLDHMNIHRTYGNERSFKCDTCNTSYKRSQDLKAHMRKVHKVVKQPRKKYVCEYCNKELSSKHSLDDHRRTHTGERPFACDKCNATFITTQRLQYHEKAHTSVRNFGCDICKRRFYLKQTLSSHMVIHRSDCPHKCPFCDKTFASGAHLKQHLPKHSDAREFKCDHCMAFYKRRDALEKHMENHELYPFSGSFKSMPRFDSTHTRHRKFKCDTCEQRFSMKSHLLSHMKIHRTDCPHKCSICDARFSDVVLLENHMVCHSDERPFKCEICGRSYKRLKALQRHTSKVHRPPSSSGEPKDFAGRRRLECDICSEIFYSTTRLHYHMRAHTGVPSFECDICERRFVLKSYLRFHMKIHLTDCPHTCQICNKKFSTNLKLQDHMVTHTDERPFKCDICDRSFKGSNHVKHHMRMIHKVDLPRSDRENLKPNQTGNSLSDVYSCDVCGKQYKQRSSLRIHQDLHKIATTVTASPRMLKHFGNVS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -