Wsmi002242.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- -
- Assembly
- GCA_029784165.1
- Location
- CM056644.1:24501467-24502814[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 6.6e-05 0.0071 18.4 1.3 1 23 55 77 55 77 0.98 2 13 3.4e-05 0.0037 19.3 2.0 1 23 83 105 83 105 0.98 3 13 0.00073 0.08 15.1 0.5 2 23 110 131 109 131 0.97 4 13 1e-08 1.1e-06 30.4 1.4 1 23 140 162 140 162 0.99 5 13 0.0002 0.022 16.9 0.1 1 23 169 191 169 191 0.97 6 13 0.0024 0.26 13.5 5.1 1 23 197 219 197 219 0.98 7 13 6.3e-05 0.0068 18.5 0.2 1 23 226 249 226 249 0.95 8 13 0.00013 0.014 17.5 1.1 2 23 256 276 255 276 0.98 9 13 4.5e-06 0.00049 22.1 0.1 1 23 282 304 282 304 0.99 10 13 7.4e-06 0.00081 21.4 3.4 1 23 310 332 310 332 0.98 11 13 2.8e-06 0.00031 22.7 0.3 3 23 340 360 338 360 0.97 12 13 7.2e-05 0.0079 18.3 0.1 1 23 366 388 366 388 0.98 13 13 0.00053 0.057 15.6 0.8 1 23 394 416 394 416 0.94
Sequence Information
- Coding Sequence
- ATGAATTTGCCCCAAATAAACGAGGAATCTATTGAAGTGCCAAACAAAGCTGAATGCATCAAGGAGGAAAGTATTATAAAAATCGAACCAGCACGCCTGCTGGCTGACGTCCTCCCGAACACATTGAGTGATGGTAAACAGCTGAAAGCTAAGGGGAAGTCTTTCGAGTGCAATgagtgtgaaaaaaaatttgcctttcgGAACTCCCTTATTTCGCACAAGCTGACGCATTCGGATGCTGGATGCTTTAACTGCAATCTTTGCGACAAAAGGTTCAAGGAACAGGTAGTCTTGAGGAGGCATTTGAAAAGGCACAGGAAGAATGTTAAATGTAATGTCTGCGGAAAAGGTTTCCTTTATCAGTTTATGCTAAAGAAGCACGCGCTGACTCACTCGGAAGATCCGGCCATACGAAAGTTCAAATGTGAGATTTGTGATAAAGCGTTCAAGAGTCAGTATAACTTGAATTTGCACTTGCGAACTCACACCAATGTCAGCAGGCCTTTCGAATGTGACGTGTGTGGGAATAATTTTGCCGTACGAGGCAGTCTGACCCGGCACAAGTTGATTCACTCCAATGAGCGATCTTTCAAGTGCGAGTTCTGTGACAAAACGTTCCACGAAAAGTACGCCCAGTTGAGGCACCAGAAAAGTCACTTCAAAAAGGAGAAATCTTTCGCGtgtgacgagtgcccaaaaacATTCGCTTACAATCAATCACTGACCGATCACAAGCTCATTATTCATTCCACAGAACAAGCAAACAAATGCCAAATATGTGGAAAAAGTTACCTTAAAAGATACCTCAGGATTCATATGCGAGTGCATACTGGCAGTCAGCTCTACAAATGCGAAGTATGTGGAAAAATCCTTTCGTCCAGAAATGAACTCGCGATTCACATGAAAATTCATCGTGGTGAAGAGCCTTTCAAGTGCGAGGTTTGCGGCAAAAACTGCTCCAGCAAATTTTACTTGAAGGCACATCTGAGATTGCACACAGAGAAAGATCTGTTCGGTTGCGACATTTGTGGCAAACAATTTACACTGAAAAGTAACCTGCAGTATCATATGGCAGTGCACCAAAATAATCGACCCCACCAGTGTGACATTTGCGGGAAAGGATTTATCACCGGTCCGCAATTGTTGGCGCACTCACGCGTGCATATCGACGAACGGCCCCATAAGTGCGACATTTGTGGCAAGTCCTACCAGAAGACACGATGGTTGGAAAACCATTTGGTTGCGCACAACAGTGGGAAAGTTGTTGCGCCGACGAAAAGTAGTAATGGATGA
- Protein Sequence
- MNLPQINEESIEVPNKAECIKEESIIKIEPARLLADVLPNTLSDGKQLKAKGKSFECNECEKKFAFRNSLISHKLTHSDAGCFNCNLCDKRFKEQVVLRRHLKRHRKNVKCNVCGKGFLYQFMLKKHALTHSEDPAIRKFKCEICDKAFKSQYNLNLHLRTHTNVSRPFECDVCGNNFAVRGSLTRHKLIHSNERSFKCEFCDKTFHEKYAQLRHQKSHFKKEKSFACDECPKTFAYNQSLTDHKLIIHSTEQANKCQICGKSYLKRYLRIHMRVHTGSQLYKCEVCGKILSSRNELAIHMKIHRGEEPFKCEVCGKNCSSKFYLKAHLRLHTEKDLFGCDICGKQFTLKSNLQYHMAVHQNNRPHQCDICGKGFITGPQLLAHSRVHIDERPHKCDICGKSYQKTRWLENHLVAHNSGKVVAPTKSSNG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01525101;
- 90% Identity
- iTF_01525101;
- 80% Identity
- -