Basic Information

Gene Symbol
-
Assembly
GCA_029784165.1
Location
CM056644.1:18600761-18612195[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 6.6e-05 0.0072 18.4 0.7 1 23 100 122 100 122 0.99
2 21 0.00051 0.056 15.6 0.9 1 23 128 150 128 150 0.97
3 21 0.00013 0.014 17.5 0.5 1 23 156 178 156 178 0.99
4 21 0.00028 0.031 16.4 0.4 1 23 184 206 184 206 0.97
5 21 0.00014 0.016 17.4 4.9 1 21 212 232 212 233 0.95
6 21 0.00081 0.088 15.0 0.3 1 23 260 282 260 282 0.98
7 21 0.021 2.3 10.5 1.6 1 23 288 310 288 310 0.97
8 21 7.2e-06 0.00079 21.4 1.0 1 23 316 338 316 338 0.99
9 21 2.5e-06 0.00028 22.9 4.6 1 23 344 366 344 366 0.98
10 21 9.8e-06 0.0011 21.0 2.0 1 23 372 394 372 394 0.99
11 21 0.00021 0.023 16.8 1.0 1 23 422 444 422 444 0.97
12 21 0.035 3.9 9.8 0.9 1 21 461 481 461 483 0.94
13 21 0.002 0.22 13.7 0.3 1 23 489 511 489 511 0.98
14 21 0.00065 0.071 15.3 1.7 1 20 517 536 517 537 0.97
15 21 6.5e-06 0.00071 21.6 1.2 1 23 545 567 545 567 0.99
16 21 0.023 2.5 10.4 2.6 1 23 666 688 666 688 0.97
17 21 0.00064 0.07 15.3 1.6 1 23 694 716 694 716 0.94
18 21 0.00018 0.02 17.0 1.0 1 23 722 744 722 744 0.98
19 21 5.4e-05 0.0059 18.7 1.8 1 23 750 772 750 772 0.98
20 21 0.00046 0.05 15.8 1.4 1 23 778 800 778 800 0.98
21 21 7.3e-05 0.0079 18.3 1.3 1 23 828 850 828 850 0.97

Sequence Information

Coding Sequence
ATGAAGGAGTTTAGCCAAATAAAGGTGGAAGAGTTCACTTCAATAAAGGTAGAAGAACTTATAATATCCGACGTTGTGGCTACGGATAACGAAACTCTGCACGCCAGCAGCGATCGGTGCTTCGAAGAACCGACTGTTACAAACGCCCTGAGGAAACAATCTACTGATGTGGAACAAAACTCTGTGACGGATATCACCGATGAAATTAGGACTAAGGCAGCTTGTGATGAAATTGCAGCTTGTAGCTCCAGAGACTTAAACAGCTCAGCCGATGTTGGTGATCAACCGCGGAAAAAGTACGTTTGCGAATTTTGCAACAAGGAATTAAGCACAAAGTCTAGCTTGGCGGGCCATAGAAGAACTCACACCGGGGAACGACCTTTTGCGTGTGATATCTGCAACGAAACATTCAACACAGCTCAACGTCTGCGGTACCATAGGAGTACTCATACGAGGGACCGGAAGTTTAAGTGTGACATATGCGAGCAACGATTCCCACTTAAATCACGTCTTGCGTCGCACATGAAAATACACCGCTCAGATTGCCTCCATAGGTGTTTAATTTGCGATGAAAGATTCCCAGATACCGATAGTCTTGCAAGCCATATGGTTCGTCACAGTAATGAGCGACCCTTCAAATGCGATGTGTGTGACAAATCATACAAGAGATCTCAAACTTTAAAGCATCATATCTGCAAATTCTACGATCCCTCCACAAGCAACTCGAAAGGTTCGAAAACGCGCAAAACCGGTGTTGGTGATCAACCACCGAAAAAGTATGTTTGTGAAATCTGCAGCAAGGAATATAGCTCAAAATACATCTTGGAGGATCATAGAAGAATACACACCGGGGAACGACCCTTCGCTTGTGATCTTTGCAACAATACATTCCGCACAGCTGTACGTTTATACTACCATAAGAAAACGCACACTGGAGACAGGAATTTCAAGTGTGACATATGCAAACAACGTTTTAGCCTTAAAGCAAGTTTGTCGGCCCACATGAATACACATCGCACAGATTGCCCTCATGAATGTCGGATTTGCCATAAAACATTCGTAAGTAATTACAATCTACTAGAACATATGCGCACTCACAGCGATGCGCGACCCTTCAAATGCGACATCTGTGACGCAACGTACAAGAGACGTCATGGTTTGAAAGATCATATGAAAATCCACAAGGTCGAGCCATCCCCAGACAACGTAGAAGCTTTGGAGCCGATTCGAGCTGGTGCCAGCCAAAGCAAAGAATCAGTGAAATATACCTGCGATATATGTGGCAAGCAGTACAAACAAATGATGGCACTTAAACTACACCTGAAATTTCATGAGAGCACCTCTGTGAGTTCTGAGATTAAAACCCGCAACACAAAGTTACACGAGTGTGCGATTTGTGGAAAAACAAATCCGAGTAGAGCATTGCTGATAAGGCACATGTTGTGTCACACGGAAGAACGACCTTTTAATTGTGATATTTGCGGTTCATCATATAAGTCAGCGTATGAAGTTGTAGTTCATAAGAAAACGCACAGCTCCGAGAGACCGTATAAATGCGAAATTTGCGGAAAAGGGTTTATTGCTCATCACAAGCTCAAGCGGCACTTGTTTTGCCATACTAATGAACGGCCTTTCAAATGCGATATTTGCGGTCTATCGTTGAGATCAGAATATAATCTAAGAAATCATAAACGAACGCATAATTCCAATCGTGAAGGGTTCACATCCGAGGCAAACCTCGTGACGCATGTAGAACAGCTTATAATATCCGACGCTGTGGAAGGAGAAACTCGGCTTACTAGCAGCGATCGGTGCTCTGATGAACCGGTTTTAACGACGAAGAGCTTAACTGATGTGAAACAAGAACCTGTGACGGGCATCATCGATGCGGTTGAGACTAACGCAACGTGTGACGAAATTGCAGCTTCTAACTCCAGCAACCTTAACGGTTCAGAAATGCACAATACCGGTGTTGGTGATTATCCGCGGAAAAAGTACGCTTGTGAGTTCTGCAACAAGGAATTCAAAGCAAAATGCACCTTGGACGAGCATAGAAAAATTCACACCGGGGAACGGCCTTTTGCGTGTGATATGTGCAGTAAAACATTTCGCACAGCCAGATATTTGCGGTACCATAAGAGTGCTCATAGAGGAGAGCGGGATTTTGAGTGTGACATATGCAAGCGACGTTTTTCTATAAAACAAAGTTTATCGTCCCACATGACTATACACCGCACAGATTGCCCTCATAAATGTCTGATTTGCGGTAAAACATTCGCAGGTAATTGCGGTCTAGTAGAACATATGCGCAGTCACAGCGATGCGCGACCCTTCAAATGTGACATATGTGACGCAACGTATAAGAGACTCCATATTCTGAAAAGACACATGGAGATCCACAAAGTCGAATCATCTCCAGGCAACACAGAATGTTCGGAGCCAAAACGGACCAATAACAGGCGAAGTGTTGAATCAGTGAAATACACCTGTGACATATGTGGCAAACAGTATAGACGATTGGGAGCACTTCACATACATCTGAAGTTTCATCAGGTCACAACCGAAATAAAATCTCACGTGCCAAAGCTGCATGAGTCGCTCGCTGGTGAAGAACAGTGTGTGGTAGTGGTGAAGTGCTTGCTTTTGGCGCGTGTGCTGGAAGGTGCAGCGCTTGTTTTTTGGTTTGCTTCTTCTCCCAGCAGAACAGGGCGATTTGATCGGAGCTCCGGCGAGGGAAAGGAGGCGGTGACGCCGTTTCTCAGACGGTGCAACATCGCAACTGTGCTGGAAGGTGTCGTGCTAGTTTTGGCGCGTGCGTTGACAGAGGAGAAAATCGGCGGCGCCGTTTTGCAGTCGATGTAA
Protein Sequence
MKEFSQIKVEEFTSIKVEELIISDVVATDNETLHASSDRCFEEPTVTNALRKQSTDVEQNSVTDITDEIRTKAACDEIAACSSRDLNSSADVGDQPRKKYVCEFCNKELSTKSSLAGHRRTHTGERPFACDICNETFNTAQRLRYHRSTHTRDRKFKCDICEQRFPLKSRLASHMKIHRSDCLHRCLICDERFPDTDSLASHMVRHSNERPFKCDVCDKSYKRSQTLKHHICKFYDPSTSNSKGSKTRKTGVGDQPPKKYVCEICSKEYSSKYILEDHRRIHTGERPFACDLCNNTFRTAVRLYYHKKTHTGDRNFKCDICKQRFSLKASLSAHMNTHRTDCPHECRICHKTFVSNYNLLEHMRTHSDARPFKCDICDATYKRRHGLKDHMKIHKVEPSPDNVEALEPIRAGASQSKESVKYTCDICGKQYKQMMALKLHLKFHESTSVSSEIKTRNTKLHECAICGKTNPSRALLIRHMLCHTEERPFNCDICGSSYKSAYEVVVHKKTHSSERPYKCEICGKGFIAHHKLKRHLFCHTNERPFKCDICGLSLRSEYNLRNHKRTHNSNREGFTSEANLVTHVEQLIISDAVEGETRLTSSDRCSDEPVLTTKSLTDVKQEPVTGIIDAVETNATCDEIAASNSSNLNGSEMHNTGVGDYPRKKYACEFCNKEFKAKCTLDEHRKIHTGERPFACDMCSKTFRTARYLRYHKSAHRGERDFECDICKRRFSIKQSLSSHMTIHRTDCPHKCLICGKTFAGNCGLVEHMRSHSDARPFKCDICDATYKRLHILKRHMEIHKVESSPGNTECSEPKRTNNRRSVESVKYTCDICGKQYRRLGALHIHLKFHQVTTEIKSHVPKLHESLAGEEQCVVVVKCLLLARVLEGAALVFWFASSPSRTGRFDRSSGEGKEAVTPFLRRCNIATVLEGVVLVLARALTEEKIGGAVLQSM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-