Basic Information

Insect: Wasmannia auropunctata
Gene Symbol: mecom-b
Assembly: GCA_000956235.1
Location: NW:2744084-2781488[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0077 0.57 10.2 0.7 2 23 311 333 310 333 0.95

2 9 0.43 31 4.7 0.1 1 23 340 363 340 363 0.93

3 9 9.4e-06 0.00069 19.4 1.2 1 23 369 396 369 397 0.93

4 9 3.7e-06 0.00027 20.7 2.6 1 23 403 425 403 425 0.95

5 9 2.2e-05 0.0016 18.2 5.0 1 23 431 453 431 453 0.99

6 9 0.00044 0.033 14.1 0.7 2 21 461 480 460 481 0.95

7 9 5.2e-09 3.8e-07 29.6 1.2 1 23 834 856 834 856 0.99

8 9 2.8e-07 2e-05 24.2 1.7 1 23 862 885 862 885 0.97

9 9 7.8e-06 0.00057 19.6 3.4 1 23 891 913 891 913 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0077	0.57	10.2	0.7	2	23	311	333	310	333	0.95
2	9	0.43	31	4.7	0.1	1	23	340	363	340	363	0.93
3	9	9.4e-06	0.00069	19.4	1.2	1	23	369	396	369	397	0.93
4	9	3.7e-06	0.00027	20.7	2.6	1	23	403	425	403	425	0.95
5	9	2.2e-05	0.0016	18.2	5.0	1	23	431	453	431	453	0.99
6	9	0.00044	0.033	14.1	0.7	2	21	461	480	460	481	0.95
7	9	5.2e-09	3.8e-07	29.6	1.2	1	23	834	856	834	856	0.99
8	9	2.8e-07	2e-05	24.2	1.7	1	23	862	885	862	885	0.97
9	9	7.8e-06	0.00057	19.6	3.4	1	23	891	913	891	913	0.99

Sequence Information

Coding Sequence: ATGAACGGCCTTGATCTGTCCCGGTCCATCGTGGATTGCAAGATGAATGGAAGCAGCGACGAAGGCGAGTCAACGTCGGGCGCGACTGGCGGGGGTGGCGGCAGCGAGAACGCAGAAATGGAGGAGAACGGATCGACTCGCAcgagcagcaacagcagcagcaacaatcCCAATTACAGAGATCTAAAGCTTCAGGGCGGTGGCGAAGGAGTTCCGCAGGAGTATAATCCGCAGTCGCGGACCGCCTATCAGCAGCGTGGGTACTCGCCGGGGATGGACCGACAACGGAATTACGAGAAGGAGCAGCTTCAACCGTCGCCGTCTTctagggaggaagagagaaaatcgTCCTGGGACTACGAGAAGAGCACGCGGAAGGAATACTCAAGGTCGCGGGATTACGGCAATGAATACCAGGATGCGATAAAACAGGAGCCCAAGGATCACTCGAGTCGCGAGTGGGTGTCGCCCGTCCCGGAGGTCGAGGTCGGCGGCTCGGCACCCGGGGGCTCGTACGTTCGTGCACGCAAAGACATCCCTCGTGGCGCGAGATTCGGCCCGTTCCTTGGCAAATGGGCGAGCGAGCCTTTCAACCCCCGTTACGCGTGGGAGGTTCGCATAGCCGGCAGTGGAGTAAGAGGCTGGTTGGACGCATCTCACGAGACGAACAATTGGCTGAAATATATACGAAGTACTGCTAGCTCACACGCAGTGAACATGCGCCACGTACTCATCGGCGGTCAGATGGTGTACGAGGCTGTTCGCGATATTGCAACGGGCGAAGAGCTTCTGCTGGGTCTTCGGGAGCCGCTTCAGCTGCAGGACATGCTGGGCGAGAATACAACCGAGGATAGAAGCGATCGAGAAACTGCCTCTCAGCACAGTGGAACTGTCGATGAGGACAAAGAGGACGAGGAAGAAGGAGAAACGAGGTGCACTGTCTGCGACAAGCCGTTCCAAGATATCGAACTATTGGATAGCCATCTGGTGACTTGTCACAGATATCCAGCGGAACAGCACCGTTGCGACAGCTGTCCCCGTGCTTACGCCTGGCGGCCGCTTCTGGTGCGGCACCGTGCTATCGTTCACGGCGATCTCAGGAACTATCCCTGCGAGAATTGTCCGAAGTCGAACATCCGGCAGGTCTTCACGGACCCATCAAACCTACAACGTCATATCCGAACTCATCACGTGGGCGCGAGAAGCCACGCTTGCACGGAGTGCGGTAAGACCTTCGCAACCAGTTCCGGCCTGAAGCAGCACACCCACATCCACAGCAGCGTGAAGCCCTTCCAGTGCGAGGTCTGTTTCAAGGCGTACACGCAGTTCTCCAATTTATGCCGGCACAAGCGCATGCACGCCGACTGTCGTATGCAGATCAAGTGCGTTAAATGCGGACAATCCTTCAGCACGGTAACGTCGTTATCAAAGCATAAGCGATTTTGCGACTCCACGACCCCGACCGGTCCGCCTGGAGCCATGCCTCAATTACCGACGCCAGCGACGAGTCCCTTTCTGGTGTATCCCCGACCTCCCGTGAGCCTACCAGGCGGTTTGCCTTTCTATCCACACGGTCTGATGGGTCCTTATCCGGGACTCTTCCCGAACGCTCCGAATTTTCTGAACACACCTCTGCTTTTTCCGCCGAAAATGGAGGAGGCCGAGAAGAGGTGCGACAGCCCGAAGAAGGAACGTTTCACTCCTCCGAGAGTATTGTCGCAACACAACAAAATCTCTCCTTCCACGGCGGAGGAAGCAACTTCTACGTTCAGGCCGTCTCCGGCTAGACCTCCGATTCAACCGACGCCGGAAAGTGACGACGATCTTTCGAAGAGAAGAGAAGCGGCTAGAAGCAACGAACGAAAAATGGAAACCGAAAGCACTTCGAAGGAGGAGACGACCGAGCAGCCGTTGGATCTGAGGGTGCAGACGAAGAAGCAGAACGTGATGTCAAAAACCGCGAATAGAAAAAGCCGCACTCCGTCGCCAGCGCCAGTGCCGATGGAGGAAACGCCGGCACCTCCCGATCCCCCGAAACCAGAGGAGGATGTTCCACCGCCGATGGAGCTCGAGTCTAAGGACATTCGAGGAAGTAGCCCGCACTTGAGGACCAGTCTGCCAATCGAACAACCACCGACCAACACGCCGCCCCACATGGCTTATCCCAGACCGATACATCCGATGTTCCTCGAAACGATGTATCGCGGTCCAGGATTCCCGGGATTTCCCAGCGCGCCGCCACCTCCAGGCGGAGCTACCCCGGAGTCTAGGCTGATACCTCCGCTTCCACCCTTCGCTCCACCGCGCGGGCTTCCTTTTTTAGGCTCGCTTATGAACGGGCTCAGCGGCGCTAGGCCAGGAGCAGGATTCGATCTGCTTGCCCGGCCGCCGCTGAGCGCGTTCCCTGGTGTGAAGCCGTTCCAAGAAGCCGTAATGCCGCCGCATCATCATCACCATCATCACCATCATCACCACGTTCACGGCAAGATGAAGGATCGGTACTCCTGTAAATTCTGCGGCAAAGTGTTTCCCCGCTCGGCCAATTTGACGAGGCATCTGAGGACTCACACTGGCGAGCAGCCGTACAAGTGTAAGTACTGCGAGAGGTCCTTCAGCATCTCGAGCAACCTGCAGAGACACGTCAGAAATATCCACGACAAGCAGCGGCCGTTTAAGTGCCCGCTCTGCGAGAGGTGCTTCGGACAGCAGACCAATCTTGACAGACATCTGAAGAAGCACGAGGCTGACGACGGTAGCGGGGTGGTGTCGGTCGCCGACTCGCCTGGGAGCAGCAACGAGAACGAGCGGGAGGACACCTACTTCGACGAGATCAGGTCCTTCATGGGCAAGGTCACCTACAGCGGTGAGAGCGGCTACGGGTTGCCGCATCATCCGGCCTATATTCCCAGTCGTCTGCACGAGATAAACGAGTCTAAGATGGAGGTCGAGTatgacgaggacgaggacagCGAGGAGGGTGTGTCCCCTTTGGAGGAGATAGACGGACTGTCGCCGATCGAGGCCAAGGAGTCCCCGTCGCCCTCGTACGACCTGAAGCTGAGAGAGAAGCAGGAGCTGCTCAATAATAATACCGCGGAGCCGGTGATCGAGATTTCGACATAG
Protein Sequence: MNGLDLSRSIVDCKMNGSSDEGESTSGATGGGGGSENAEMEENGSTRTSSNSSSNNPNYRDLKLQGGGEGVPQEYNPQSRTAYQQRGYSPGMDRQRNYEKEQLQPSPSSREEERKSSWDYEKSTRKEYSRSRDYGNEYQDAIKQEPKDHSSREWVSPVPEVEVGGSAPGGSYVRARKDIPRGARFGPFLGKWASEPFNPRYAWEVRIAGSGVRGWLDASHETNNWLKYIRSTASSHAVNMRHVLIGGQMVYEAVRDIATGEELLLGLREPLQLQDMLGENTTEDRSDRETASQHSGTVDEDKEDEEEGETRCTVCDKPFQDIELLDSHLVTCHRYPAEQHRCDSCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSNIRQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTTPTGPPGAMPQLPTPATSPFLVYPRPPVSLPGGLPFYPHGLMGPYPGLFPNAPNFLNTPLLFPPKMEEAEKRCDSPKKERFTPPRVLSQHNKISPSTAEEATSTFRPSPARPPIQPTPESDDDLSKRREAARSNERKMETESTSKEETTEQPLDLRVQTKKQNVMSKTANRKSRTPSPAPVPMEETPAPPDPPKPEEDVPPPMELESKDIRGSSPHLRTSLPIEQPPTNTPPHMAYPRPIHPMFLETMYRGPGFPGFPSAPPPPGGATPESRLIPPLPPFAPPRGLPFLGSLMNGLSGARPGAGFDLLARPPLSAFPGVKPFQEAVMPPHHHHHHHHHHHVHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYSGESGYGLPHHPAYIPSRLHEINESKMEVEYDEDEDSEEGVSPLEEIDGLSPIEAKESPSPSYDLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01407591;
90% Identity: iTF_01261975;
80% Identity: -