Basic Information

Insect: Volucella bombylans
Gene Symbol: Thap1
Assembly: GCA_949129095.1
Location: OX422144.1:158426234-158428568[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.056 24 8.0 1.5 1 23 413 436 413 436 0.94

2 9 0.065 28 7.8 1.3 3 23 465 486 463 486 0.94

3 9 0.00033 0.14 15.0 0.1 2 21 499 518 499 519 0.94

4 9 9.4 4e+03 1.0 1.6 1 9 532 540 532 544 0.90

5 9 0.3 1.3e+02 5.7 0.8 3 20 596 613 595 615 0.91

6 9 2.2 9.3e+02 3.0 2.6 3 20 631 648 630 650 0.94

7 9 4.4e-07 0.00019 24.0 0.9 1 23 656 678 656 678 0.99

8 9 9.3e-06 0.004 19.9 1.9 1 23 684 707 684 707 0.96

9 9 0.77 3.3e+02 4.4 0.1 1 15 713 727 713 730 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.056	24	8.0	1.5	1	23	413	436	413	436	0.94
2	9	0.065	28	7.8	1.3	3	23	465	486	463	486	0.94
3	9	0.00033	0.14	15.0	0.1	2	21	499	518	499	519	0.94
4	9	9.4	4e+03	1.0	1.6	1	9	532	540	532	544	0.90
5	9	0.3	1.3e+02	5.7	0.8	3	20	596	613	595	615	0.91
6	9	2.2	9.3e+02	3.0	2.6	3	20	631	648	630	650	0.94
7	9	4.4e-07	0.00019	24.0	0.9	1	23	656	678	656	678	0.99
8	9	9.3e-06	0.004	19.9	1.9	1	23	684	707	684	707	0.96
9	9	0.77	3.3e+02	4.4	0.1	1	15	713	727	713	730	0.82

Sequence Information

Coding Sequence: ATGCCCTCTTTCTGCGTTGTTAAAAACTGTGAAGACAAATATACACACTCTGAGAGTGTTTCATTTCACAAGTTTCCCCACAGCCGGAAAGACCTCTTAGAGAGATGGACAGAGTTTGCTTGCCGAGGTCCGGACTGGAAGCCATCCAAATGGAGTGCAATATGTAGCCGTCACTTTCTGCCAGAAGACTTTCGTAATGTAAATTCTAGAAAGGCTTTGAAAAAAACTGCGATTCCTACTGTGAGACCATCTGAAAGTGAACAGATTTCACCACTACCTCCCTTGGAAAATCATCCAGATGATTTCAAGttaccCGATAGTAGCTGTCGATTGTGTGGAATCTGTTGCCGTCCAGTGGCAACTTTTGCAAccaatttcgaaatttttggcatgattcaaaaatgttttcccaCTCTAAACATTCAGTTGGATGACAATCTACCAAAAGATATGTGCTCTGGTTGCTTAAAGAGATTAAATAGTTTCTCAGAATTTGTCGATGCAGTTCTGGAAACTCAAAAAGTTCTTCAAGGCAAGTTCCGCAGTGAGAAATTCATGAAACCACCTGAAAGGCAACTAAAAATCAAGCAAGAACCAGTGGTGAACGTAAAACAAGAAGTCGGGGAGAATTTCGACAGTTTTCTTAGTGATGATTTGGAAGAAGACCAGGACTGCGAGCAGAAATTCCCATTTTGTGACTTCCCCATTCTCAATACCCAGGACATAATCAACAACTGTGATATTATGGAAATAATCAATCTTGACGATCCCTTCATTGACATTCCCGATGATGAGAATGGCAACGAGGTGGATCATATTGACCAAGTAGACTACTTTGAACCCAAGTCTCAGCATGTGCTCAATTTGGGTACGGGCTTGATGATACATGAGCACAATTATGCGTTGCCGATTGAATGCAAAGATTCGATTCCATTTACAAATGTTTACAAGACTGAAAAGGCTGAAGAAAAGGAGGAAGCCATTGTTACAAATGCCCCGCCCTCTACACTTATAACAGCAAAGCCCAAGTACTCAAACAATCGTACGATAGTCAGTGAACCCGCTAGACTCAACAGCAACTTTCTCTTCTCGGACACTTCCAATTCAGCGGGAAAAATTATGGTAACATCTGTGAGTAATTTACAGCCGCTACCAGCTGTGGAAACAAGCACTAAGAAGCCCAACATCGTCGTTCTAAATGAAAGCATTGTTAAGACAGCTTCAGCATTCCAGCTGCATCCATGTTCCATGTGCCAGTCTCAATTTTTTTCCAGCGAAGGTTTGAGCCATCACATTATCAATGCCCACATGCACCCAACTGCTATGGTAAGTTTACCTATGGACAGTGTACCTGTGCAAGAGGTAGCTAAGCCACATACGAAATCCATAAATTGTCCATCTTGTTCGATGAGCTTCGTAACTATTCAGGGTCTtctcaaacacaaacacaaaactCACTCCAAAACGATACCGAAGCGCGAGAAACGAGGGAGAGAATGTCCCGTATGCGAAAAGTTCTTTATCAGCAAAGTGGCGTTGAAAAATCACCGTCAATACGTATGCCAAACGAAAGCACTTACTACTTCAAATAACTTTAAATGCCGATACTGCCAAAAGAACACCTTTGGTCACTGGAGAATATACCGAAATCATGAGACTCTTTGCAAGCGTAGACGAACGAAGAAACCCCAACAACCGAAAAAAGTATCCAAACCAATAGTTCTGGCCGATAAACTatcaaaggaaaaattaaactcACATGCTCCTGATGATTCCAACCTTCTTTGCCTTGGATGTGACAAAAGATTCAGCCTCGTCGATTGCTTCCGACTGCACTACATCAATGAACAGTGCAAATTTAAGCCTTCTTCTGACGAGGTTCTTGCATTTTGTCGCACTTGCAATAAACCCATAACAACGTTTACGAAACTTCGCTCCCATCGCcactttaaaatttcaaagaagtACCAGTGTAAGGACTGTCCAAAGGTATTTACGTCGTCGAATCTGTTATCACAGCACCGAATCACGCACTCAAATGTCCGGAAACACAAGTGTGAACTGTGCGAGAAGATATTTAAGAGAAGAGGTGGCTTGCAACAGCACATGAAGGGTTATCATTTGAAGATGAAGCCACATGAGTGCGGAGTGTGTAAGCGACGTTTTGCGTTAAAAGCAGATATGTCACGCTGCAAGCATTCATCATTAAAATATTAA
Protein Sequence: MPSFCVVKNCEDKYTHSESVSFHKFPHSRKDLLERWTEFACRGPDWKPSKWSAICSRHFLPEDFRNVNSRKALKKTAIPTVRPSESEQISPLPPLENHPDDFKLPDSSCRLCGICCRPVATFATNFEIFGMIQKCFPTLNIQLDDNLPKDMCSGCLKRLNSFSEFVDAVLETQKVLQGKFRSEKFMKPPERQLKIKQEPVVNVKQEVGENFDSFLSDDLEEDQDCEQKFPFCDFPILNTQDIINNCDIMEIINLDDPFIDIPDDENGNEVDHIDQVDYFEPKSQHVLNLGTGLMIHEHNYALPIECKDSIPFTNVYKTEKAEEKEEAIVTNAPPSTLITAKPKYSNNRTIVSEPARLNSNFLFSDTSNSAGKIMVTSVSNLQPLPAVETSTKKPNIVVLNESIVKTASAFQLHPCSMCQSQFFSSEGLSHHIINAHMHPTAMVSLPMDSVPVQEVAKPHTKSINCPSCSMSFVTIQGLLKHKHKTHSKTIPKREKRGRECPVCEKFFISKVALKNHRQYVCQTKALTTSNNFKCRYCQKNTFGHWRIYRNHETLCKRRRTKKPQQPKKVSKPIVLADKLSKEKLNSHAPDDSNLLCLGCDKRFSLVDCFRLHYINEQCKFKPSSDEVLAFCRTCNKPITTFTKLRSHRHFKISKKYQCKDCPKVFTSSNLLSQHRITHSNVRKHKCELCEKIFKRRGGLQQHMKGYHLKMKPHECGVCKRRFALKADMSRCKHSSLKY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01523002; iTF_01522204;
90% Identity: iTF_01523002; iTF_01522204;
80% Identity: -