Vcin026095.2
Basic Information
- Insect
- Villa cingulata
- Gene Symbol
- CG10628
- Assembly
- GCA_951394055.1
- Location
- OX596022.1:2309569-2315003[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0036 0.45 12.3 2.2 1 23 87 109 87 109 0.95 2 12 0.57 71 5.4 2.3 1 23 115 139 115 139 0.94 3 12 0.032 4 9.3 0.7 1 23 142 165 142 165 0.97 4 12 0.34 43 6.1 0.3 3 13 175 185 174 187 0.89 5 12 0.01 1.3 10.9 2.6 1 23 189 211 189 211 0.97 6 12 6.9e-05 0.0085 17.7 0.4 1 23 217 239 217 239 0.96 7 12 0.56 70 5.4 5.1 1 21 245 265 245 266 0.93 8 12 0.0045 0.56 12.0 3.1 1 23 472 495 472 495 0.96 9 12 0.00019 0.024 16.3 1.1 2 23 513 534 512 534 0.96 10 12 6.5 8e+02 2.0 4.8 1 23 542 565 542 565 0.94 11 12 0.00019 0.023 16.3 0.5 2 23 570 592 569 592 0.96 12 12 0.00022 0.027 16.1 0.4 3 21 639 657 638 658 0.94
Sequence Information
- Coding Sequence
- atggaaaaaattgaaaagcaaGTATCTTGGTCTGATTCTGATGAATCTGATGAAACTGATGAAGAATCACcaagaaaatttgttaaaaatgatgaaagaagaTGTAAATATTGTGGTCAGAATGAGAATGTtacagaatatttttttcaaattAAACTATTTCGTAATGAATTGAATGTTGAACGACATgggaaaatatgtaaaattggtGCAAAAAATACTGCAAAACTGGTAAAAGCAAAAGATGGTAATATACGATTTTTATGTGATGTATGTTATcggacatttaaatttttaacgggcctaacaaaacataaattaagACATGAACCGCCCGGCGgatatgaatgtaaattttgCGATAATACACGATATTGTACAGATGCCGAATTACAAAAACATAAAGAAATTATGCACatggtatataaatgtaagatTTGCAAAGAAAAAATGGATAACAGAGATAAATATGTCGAACATATATTACGTGTACATGATGGACGTCAACTTTTATATGCGATTTGCGAAGATTGTGGCCAACAATTTCGTACTCgtgaaaaaaaattttgctgtTCATATTGTGGTAACAGTTTCTTGAAAAAAGGACAACTTGTTGTACACGAAAGAAAGCATACTAAAGAGAAACCGTTTGTATGCAAtatCTGCTCAAAAGCATTTTCATATCGTGAAAGTTTGGTAACACATTCATCAGTTCACACCGGTATTAAACCGTATTTATGTGAGGCATGCGGTGCATGCTTTTCATGTTTCAGTAATTTACAGAAGCATCGTCGTCATCGTCCAAATACATGTGGCCAACCACaattcaatacaaatacaaaaattgctCCACGAGCAAGTTTTAAAtccgGTAAACTTACAAGACAAATTAAAGTCGGAAAAGGAAATTTAGTTTTAGAAGGTACAAAGAGGCCAACTGAAAATAATGCAAATGTTAAACAGAAGGTAAAATGCAAAATGAAAATTTCAGAATTATCTgagaatgatgaaaatgaacaaTATGAGCATaattatgaaattcaaatttataatgaatCATCAAATAATTCTGATGATAAAcgtaatactgaaaatttattgaatcaAATTGAAATCATTAATACAAGCAGTAACCATTTGGACGatgaaaatttcgaagcaaaagaaaaagaaaaaaaggaaatattaaTCGAATTTGATGAAAAGGATGAAGACGATAATGCTTCACTTACAAAATGTGtgaaagaaaaatctgtagaagAGaaaataattaaaaaatgtaaaattgaaattactgCAAATGATGATAACCATGAAAAATTTCCTCCATCACCACCATCTGAATccaataattcaaattcaaatttaaattcaaaaaaatcaaatcatacAATCAAAGATACAAATAAATTGTTCGAATGTGATAAATGCCCAAAATTCTATCATCAACGTAAATCATATGTAAAACATTTGGTTACCGATCATGATATGAATTTGATCGATGTTGAAAAATCTTTAGATGATATCGAAATGATACGATGTAAATATTGtgcaaaaatttacaaacaaaatgCATCAttgaaaaaacatgaaaaattgcATGGTCCTAAAGgtaaattaattcataaatgTCCATGCTgtcgaaaatattttgaaacaaTTGAAGATGCTAAAAGGCATACAAAAGCCAAACATTCCGATCAATTAACATGTACGGTATGTCAGAAGATGTATACTGATTTGAATGCATTGATGGCGCATCGAAAACGTTTACATTCAACGATTGCAGTAACATATTCAggcaataatgatgatgatgatgatcgtgGTGATCACGATGACAATAATTCAACAGaaaatacaattgaaaaattaataaatgaaagaatgaaaaaaatgcaacatactcgtatatgccaGAAATGTGGTAGAAAATTTGCCAGTAAAACAGCATTAAATAATCATGAGAGATCTGATTGCGCTGGTGGTGGTATGGATGGTTGTACAGCAACATCATTTCTATGGAAACCCGGTGATTCTAGAACGATAACAttagatttaaaattaattgctgATGTTGGTTTAGTTGGATTTCCAAATGCTGGTAAAAGTACACTATTGAAGGCGATATCGAATGCATCACCAAAAATTGCATCGTATCCCTcGAATAAAGTTGAAGGCACAAAACAACATTTACAGTGGCCATAG
- Protein Sequence
- MEKIEKQVSWSDSDESDETDEESPRKFVKNDERRCKYCGQNENVTEYFFQIKLFRNELNVERHGKICKIGAKNTAKLVKAKDGNIRFLCDVCYRTFKFLTGLTKHKLRHEPPGGYECKFCDNTRYCTDAELQKHKEIMHMVYKCKICKEKMDNRDKYVEHILRVHDGRQLLYAICEDCGQQFRTREKKFCCSYCGNSFLKKGQLVVHERKHTKEKPFVCNICSKAFSYRESLVTHSSVHTGIKPYLCEACGACFSCFSNLQKHRRHRPNTCGQPQFNTNTKIAPRASFKSGKLTRQIKVGKGNLVLEGTKRPTENNANVKQKVKCKMKISELSENDENEQYEHNYEIQIYNESSNNSDDKRNTENLLNQIEIINTSSNHLDDENFEAKEKEKKEILIEFDEKDEDDNASLTKCVKEKSVEEKIIKKCKIEITANDDNHEKFPPSPPSESNNSNSNLNSKKSNHTIKDTNKLFECDKCPKFYHQRKSYVKHLVTDHDMNLIDVEKSLDDIEMIRCKYCAKIYKQNASLKKHEKLHGPKGKLIHKCPCCRKYFETIEDAKRHTKAKHSDQLTCTVCQKMYTDLNALMAHRKRLHSTIAVTYSGNNDDDDDRGDHDDNNSTENTIEKLINERMKKMQHTRICQKCGRKFASKTALNNHERSDCAGGGMDGCTATSFLWKPGDSRTITLDLKLIADVGLVGFPNAGKSTLLKAISNASPKIASYPSNKVEGTKQHLQWP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -