Basic Information

Insect: Vespula germanica
Gene Symbol: mecom-b
Assembly: GCA_905340365.1
Location: HG996549.1:2589435-2595309[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.022 1.4 9.3 0.4 2 23 67 89 66 89 0.93

2 9 0.04 2.4 8.5 0.1 1 23 96 119 96 119 0.94

3 9 4.2e-05 0.0026 17.8 0.5 1 23 125 153 125 153 0.95

4 9 4e-06 0.00024 21.1 2.6 1 23 159 181 159 181 0.95

5 9 2.4e-05 0.0015 18.6 5.0 1 23 187 209 187 209 0.99

6 9 0.00048 0.03 14.5 0.7 2 21 217 236 216 237 0.95

7 9 5.7e-09 3.5e-07 30.0 1.2 1 23 600 622 600 622 0.99

8 9 3e-07 1.8e-05 24.6 1.7 1 23 628 651 628 651 0.97

9 9 8.4e-06 0.00052 20.0 3.4 1 23 657 679 657 679 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.022	1.4	9.3	0.4	2	23	67	89	66	89	0.93
2	9	0.04	2.4	8.5	0.1	1	23	96	119	96	119	0.94
3	9	4.2e-05	0.0026	17.8	0.5	1	23	125	153	125	153	0.95
4	9	4e-06	0.00024	21.1	2.6	1	23	159	181	159	181	0.95
5	9	2.4e-05	0.0015	18.6	5.0	1	23	187	209	187	209	0.99
6	9	0.00048	0.03	14.5	0.7	2	21	217	236	216	237	0.95
7	9	5.7e-09	3.5e-07	30.0	1.2	1	23	600	622	600	622	0.99
8	9	3e-07	1.8e-05	24.6	1.7	1	23	628	651	628	651	0.97
9	9	8.4e-06	0.00052	20.0	3.4	1	23	657	679	657	679	0.99

Sequence Information

Coding Sequence: ATGGTAGTACGATGGGTGTTGCGGCCAGTTCCCATGAAGGTCCGTTGGGGGCCATCGTTAGACCATATGGTCTTAGTACGGACAAGTGTAGCGGCAGATTTAAATAACCGTTGGAGGTCTACTACGTTATTTTCAAAAGCATCTCAACATAGCGGTACAGTCGATGAAGACagagaggacgaagaggagagCGAGACGAGATGTACTGTCTGTGACAAACCCTTTCAAGACATAGATttATTGGACGGACACCTGGTGACTTGTCATAGATATCCAGCTGATCAACACCGGTGCGACGATTGTCCACGTGGTTACGCTTGGCGAGCACTTTTAGTTCGTCATCGAGCCATTGTTCACGGCGATCGAAGGAATTATCCTTGCGAAAATTGCCCGAggTCGAACACCCGACAGGTTTTTACGGACCCGTCTAATCTCCAACGTCACATACGTTCGAATCACGTTGGGGCGAGGAGTCACGCATGCACCGAATGCGGGAAAACGTTCGCCACGAGTTCCGGATTGAAGCAACACACTCACATTCACAGCAGCGTTAAGCCATTTCAGTGCGAGGTCTGTTTCAAGGCGTACACTCAGTTCTCCAATCTTTGCCGACACAAACGCATGCACGCGGATTGTCGCATGCAAATAAAGTGCGTCAAATGTGGACAATCCTTCAGCACGGTTACGTCACTGTCGAAGCATAAACGTTTCTGCGATTCAACGACACCGACTGGTCCACCAGGAACAATGCCACAATTACCAACTTCGGCGCCTAGTCCTTTCCTCGTTTATCCGAGACCACCGGTCAGTCTACCAGGTGGTTTACCATTTTATCCGCCTAGCCTGATGGCACCGTATCCTGGGATATTTCCAAATGCACCGAACTTTCTAAACTCCCCGTTACTTTTCCCACCTAAACTCGACGACGGTGATAAAAGAAGCGAGAGCCCGAAGAAGGAACGTTTCACCCCGCCAAGAATTCATCCCCAACACAGTAAGATATCGCCGTCGGCCGGCGAGGAGGCAACCTCGTTGTTCAGGCCGTCACCGGCCAGGCCACTCGTTCACCCAACGTCAGAGTCCGAAGACGATCAGAGCAAGCGTCGTGAGAACCTTGGAAAGtcggtagaaaaaaaaatggaaatcgAAACGGCGACGAATTCTACGACCGAAGAATCGACAGATCAGCCTTTAGATCTAAGGGTGCAAACGAAGAAGCAGGACGTATCGatagacgagagaaagagtcgtAGTCCTTCGCCAACGCCAATAACCGTCGAGGAACCTCCGCCACCACCTGTGGATCCAccgagaacgaacgaagaggaaaatgTCGTACCGATCCCATCGATGGCTGTCATCGATACGAAGGACGTAACGAGTAGTCCGCGGCTCAGAACGAATCTTTCAACAACGGATCAAACGCCAACGAATACCCCTCCGCACATGGCGTATCCCAGACCGATACATCCGATGTTTCTGGAAGCCATGTATCGTACACCTGGAAATACTTTTCCTGCATTCCCAGGTGCTCCTCCTACGGCAGGAGGTGCTTCGGCCGAATCGAGATTATTACCACCTCTTCCACCGTTCGGGCCACCCCGTGGACTTCCTTTTTTAGGGACACTAATGAACGGGCTCAGCGGCGCCAGGCCAGGAGGGGGATTCGACCTGCTTGCCAGGCCGCCGATGGGTGCGTTCCCCGGCGTGAAACCGTTTCAAGATGCCGTAATGCCAccccatcaccatcatcatcaccatcaccatcatcacgCGCACGGTAAGATAAAGGATCGTTACTCGTGCAAGTTTTGCGGAAAGGTATTCCCGAGATCGGCGAATCTTACCAGGCATTTACGTACCCATACCGGCGAACAACCTTACAAGTGCAAATACTGCGAAAGATCGTTCAGTATATCCAGCAATCTACAACGACACGTTAGAAATATTCATGACAAGCAACGACCGTTCAAGTGTCCCCTTTGCGAGAGATGTTTCGGTCAACAAACCAATTTGGATAGACATTTGAAAAAGCACGAGGCAGACGATGGCAGCGGTGTTGTCTCCGTAGCTGATTCTCCTGGCAGTAGCaacgagaacgaacgagaggaCACGTATTTCGACGAGATCAGATCGTTCATGGGTAAAGTAACTTATGGTGGTGAACCTGGTTATCATTTGCCACCTCATCCAGCATATTTGTCCGGTCGTTTGCACGATATACATGAGTCCAAAATGGAAACTGAatacgacgaggacgaggacagCGAGGAAGGCGTTTCACCTCTCGAAGAGGCTGACGGTCTTTCGCCCTTAGAGACCAAAGATTCTCCCTCGCCGTCCCAATACGATCTTAAGCTGAGAGACAAACAGGAATTGCTCAACAATAATACAGCCGAACCGGTTATCGAGATCTCCACATAA
Protein Sequence: MVVRWVLRPVPMKVRWGPSLDHMVLVRTSVAADLNNRWRSTTLFSKASQHSGTVDEDREDEEESETRCTVCDKPFQDIDLLDGHLVTCHRYPADQHRCDDCPRGYAWRALLVRHRAIVHGDRRNYPCENCPRSNTRQVFTDPSNLQRHIRSNHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTTPTGPPGTMPQLPTSAPSPFLVYPRPPVSLPGGLPFYPPSLMAPYPGIFPNAPNFLNSPLLFPPKLDDGDKRSESPKKERFTPPRIHPQHSKISPSAGEEATSLFRPSPARPLVHPTSESEDDQSKRRENLGKSVEKKMEIETATNSTTEESTDQPLDLRVQTKKQDVSIDERKSRSPSPTPITVEEPPPPPVDPPRTNEEENVVPIPSMAVIDTKDVTSSPRLRTNLSTTDQTPTNTPPHMAYPRPIHPMFLEAMYRTPGNTFPAFPGAPPTAGGASAESRLLPPLPPFGPPRGLPFLGTLMNGLSGARPGGGFDLLARPPMGAFPGVKPFQDAVMPPHHHHHHHHHHHAHGKIKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEPGYHLPPHPAYLSGRLHDIHESKMETEYDEDEDSEEGVSPLEEADGLSPLETKDSPSPSQYDLKLRDKQELLNNNTAEPVIEIST*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01090161;
90% Identity: iTF_01512342;
80% Identity: -