Basic Information

Insect: Vespa mandarinia
Gene Symbol: ZFX
Assembly: GCA_014083535.1
Location: JACHAV010000013.1:2774024-2779103[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.95 68 3.7 0.1 3 23 19 39 18 39 0.94

2 15 0.78 56 4.0 2.7 1 19 893 911 893 916 0.75

3 15 0.0065 0.47 10.5 1.8 2 23 997 1019 996 1019 0.95

4 15 0.0064 0.46 10.5 0.1 2 23 1032 1053 1032 1053 0.98

5 15 1.7e-05 0.0012 18.6 2.1 2 23 1056 1077 1055 1077 0.97

6 15 0.016 1.2 9.3 0.4 1 23 1083 1105 1083 1105 0.95

7 15 1.9e-05 0.0013 18.5 4.5 2 23 1112 1133 1111 1134 0.95

8 15 0.13 9.3 6.4 1.7 5 23 1147 1165 1146 1165 0.96

9 15 1.7e-05 0.0012 18.7 1.5 3 23 1172 1193 1171 1193 0.97

10 15 0.0077 0.55 10.3 0.3 2 23 1209 1229 1208 1229 0.97

11 15 5.1e-05 0.0037 17.2 0.7 1 20 1235 1254 1235 1257 0.92

12 15 6.3e-05 0.0046 16.9 2.7 1 23 1265 1287 1265 1287 0.99

13 15 0.0018 0.13 12.3 3.2 1 23 1293 1315 1293 1315 0.97

14 15 3.2e-06 0.00023 20.9 3.9 1 23 1321 1343 1321 1343 0.99

15 15 0.0011 0.08 12.9 6.3 1 23 1349 1371 1349 1372 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.95	68	3.7	0.1	3	23	19	39	18	39	0.94
2	15	0.78	56	4.0	2.7	1	19	893	911	893	916	0.75
3	15	0.0065	0.47	10.5	1.8	2	23	997	1019	996	1019	0.95
4	15	0.0064	0.46	10.5	0.1	2	23	1032	1053	1032	1053	0.98
5	15	1.7e-05	0.0012	18.6	2.1	2	23	1056	1077	1055	1077	0.97
6	15	0.016	1.2	9.3	0.4	1	23	1083	1105	1083	1105	0.95
7	15	1.9e-05	0.0013	18.5	4.5	2	23	1112	1133	1111	1134	0.95
8	15	0.13	9.3	6.4	1.7	5	23	1147	1165	1146	1165	0.96
9	15	1.7e-05	0.0012	18.7	1.5	3	23	1172	1193	1171	1193	0.97
10	15	0.0077	0.55	10.3	0.3	2	23	1209	1229	1208	1229	0.97
11	15	5.1e-05	0.0037	17.2	0.7	1	20	1235	1254	1235	1257	0.92
12	15	6.3e-05	0.0046	16.9	2.7	1	23	1265	1287	1265	1287	0.99
13	15	0.0018	0.13	12.3	3.2	1	23	1293	1315	1293	1315	0.97
14	15	3.2e-06	0.00023	20.9	3.9	1	23	1321	1343	1321	1343	0.99
15	15	0.0011	0.08	12.9	6.3	1	23	1349	1371	1349	1372	0.96

Sequence Information

Coding Sequence: ATGGATCTTGGCATCGTAGGTAATGCAACGGGTGCATCCGGGGGGGCCGTCGCCTGTCCCGTTTGCACTCTTTATTTGCGCGAGGGTATCAGCCTTCAAAGACACTTGGATACACATCCCAAGGAACAGGTCATAGAGGCCCTCATTAAAGCCAGCTCTACGACCTCTCAACAGACACAACAACTTCCATCGCCAACATCAGTACCTCCTGTTCCTTCCAGCATTCAATCACCACAGAATACACCGCAGCACATCCAACAGACGACTGCACATGTTTCTGCTCAGTCTCCATATCCCATAGGGCCTATATTTGAATGTCCACCGATTGGTACTATGATGCCTCCTCAATTTGCCTCGTTTAGTTATCAACAATTTGTCAATAATGGGACCATGATGATACCACAGTACGCAATGGCTCCGCAGACTAATCAGATGATGCAAATGTTGTATAATCCATATGGTATGTATCAGCAGCAACAGATACCTACTGTTCAAATGATCTCTCCGGTTGCAGCCATTCCTAATACCACAAGGATAAGACCTGTGGTTACTATGGCTGGTGAAACCAATAACAGGACCACCATCACCGTACCTGTAAATAGTTCTGAGCCAAAGCAGATCTTACCTGAGATATTGCCAGAGCCTGAAGTAGAAAATGAACAAGATCTGCCTGACATAAATTTCCCAGCATCCCCCGAAGTAGCTAATGAAAATACTTCTATGCAGCAAGATGGAAATGAAAATAGTAGAATTCAAATAGAACATAGAGGCCAACAGATACAAAATCCAACCATTCAGGATCAAAGTTCTGTGCAGCACGAATACAATAGCATTCCTAGATCTTTAACTATCGCTTGTAACATtgaaaatgaagatgatgacAATGCCGAAAGTGTATTGCCTGATATagacgaaagagaaacggCACACATAGTTGCATCGGTTGTCCAATGCAAACCCACACATTATGAAGAACAATCTGAAATACGAAGGTTTgatcaagaatataaaaatgatactaGTAAGCTCAATTTAGAAACGCAAGATGTACTTGGAAATACTATTgcaatagaaaaggaaaaattagaGGGGGAGAAGTCTTCggatgaaaaagataagagtGAAAATGAATCTGTCCCATCTCAAGTTCCTTCAACAGAAATGACAAAAGATACTGCACAACCTGAGGTAGAACAATTGGAACAATTATTAATCACTATTATGGAATCAGAATTTAATAGTGCATCAACGAAGGAGCATGACGTACAGAAGGATGAGGAAGGGAAGGAAAGTATGGAGGAAAGTGCTTCAGTTCATGCGGACGAGGAAATAACTCCGAATATAATAGATGTGATTTCAAACTCTCATAGCAGTGATATCAAGGAATGTAATATAGAAATGGAAATTACGGAAGAACCAAAAATATGTGTAGAAGACAAATCAGAcaaaagttatattttatatcattacaaGGACAGTTTATCTGCTCCACCCTCGCCAGCAATACGAAAGAAGTCTACTCGAACATATTCAGTTCGTTCAGAATTTGgatcaaacgaaaatcttAGTGTTTATCCTGTCGGATTTGATGCTACTACATTGCAAGACgaagaggacgacgacgaaaagAACATGACAGAAGATAATTTTGATGAAGCAGACATGGAAATAGAAGCAATACCTAGTCCTCATACACCTTTCATGAAGTATGGTGAAAGTGCAGATGGTGTTAGATCCCATACTCCATTGTCTGCTATTAGTGGTATATCAGTACTAAGAGTTCGAAAAGATTTAAGCAAACCTTGTTCTCCTGCATCTGCACATTCATTTTGTCATATAGATGGTGATAGTTTGAGCCATGATGATGAAAGTAACGATTTAAGAGAAATTACAATGGAAAAAGATCCTATTAGTTGTCCACAAATTGAAGAAGAATTGAAAGTTGATAAATATGAAGAGAATGTATGTGAAAATGTGGAGAAGAAGGGTAATAATTCAAATCATGTGTATCATCAATCTGTAATAACAGAGCATGTTAGCTTATTTCCACCAATTCATTCTCAACAACCTGTTTTAATACAGGATTCTTATCCATTACCAAATAACAAAAATcataatcttttaaatttatcagAATCCATCAATCCAACTACAAGCACTGAATCAAAGAATTATCATTGTAGTAAATCAATTATTCAAAAACAGTCAATGGAACTTCTTAATATAAATGAGGATGCTCATGCTGGTCCAATGAATGTTTTTGAGTTTGATGGACTTCAAATTTTAGTTCCTAGTACATTTATAAGTGAATCATCACAAAAAGCAGTGAGTGCAACTAGCCAGCAATCTATGGCAAGTAGCGAGGGAGGTGCAGGTATTGACGAAGAAGTCAAAAGTGTTAATATGCGTGCTGACGAAACTATGCCACCCAGAGGTGAATTATCAGAACAAGAAAGTAATGGCTGTACAGAACAGTCTGCTTGGCAGgTTTATATGGGCCAAGAATCTTCAAGAATGTCAACTTCTTATGATCTAATGGCAAGGGAAAGTTGGGAAGAATCAGAAGGATCAGACAATGAAATTAGTGGTCCATTGTTAGATAGTCGATCTTTAGCTACGCATTTTACATCTAGCTTATTCTTAGATCGTGATAGAAAGACGCCTACAAAAAGGACATTTAAATGTTCACATTGTCCAGAGGTTTTTGACTGTCCTAAAGAACGTAGAGTCCATAGTACAATGGTGCACAAAGAACCTGGACCTAGCGGTAGTAGAGATGCAACAGAACAACCAGaagtaaaagatataaaattattagacGGGCGTATGAATGTGTTTGATGATATTTTTGTACCAGGCTTACATGTGCAACAAATGTATCATCAACAGCCATTGTTACATCAACTCCAACCGCCACAACCAGATTTAGCAAAAATAGAAACCGATCAGAAAGGTGAAAATTTGACAATTCCTTCGACAGTAGAGGTATCTTGTGCATTATGCAATCAACGATTTAATAGTGAAAAAGCTTTACAGTTACATCATAAGAGAATGCATATAGTTGAAGTATCGAAACGTATTCGTGAACAGGCAAAATGCGTAATATGCAACGAAGAATTCCCATCTGTTGTATTGTTTAATGCTCACTTAAAAATACATCCGTTAGAATGTGGACAATGCGGAAAATACTTTTATAGAAagcaaaattataaattacacaTGAAACGTCATTTAGGAATCAAGCCCTTCCCTTGTACACTATGTGATAAGGCATTTttaactaaacaaaaattagATGAACATACTAATGGACATACAGGTAATGCCCCTGTAAAGTGTAATTTGTGTAATGAAACTTTTCGTAGATATTCAAATTTAACTCAGCACAAGAATAGACATCatcttaatattaaaaagaaattgaaagacTATATATGCCAATGTGGAGAGATATTccatacgaagaaaaaattagcaTGGCATAAAGAGACACATGATGAAAAACCTAAAGCATGCACATATTGTAATGAAAGATTTATACATATGGCTAGTCTTACACGTCATATGCGTCGTGCTCACAATAGGAGATTTGTTCCTGATGctcaaagagaaaatgaaaatgtggAGTGTCcaatatgtaaatgtatttatttgcgATCATCCTTAGCCGTTCACATGCGTGTCCATAATGGTGAAAAACCCTATGAATGTCAGGTTTGTTCCAAGGCTTTTAGTACGAAATGGAATTTACAATTGCACAAGTGGACTCATGCAGCACGTAGCACGAAACCATTTAAGTGCAACCAGTGCAGCGCTGCATTTTATCGACACAGTGATTATACAGCTCATATGAATTCTCATCGGAATGTACGTCCATATACGTGTAATTACTGTGGAGCTCAGTTTATACGAAAGTATAACTGTTTAAGACATGTAAAAGAACACGAGGAGAATAAGGCATATACATGTGACGTTTGCAACAAAACTTTTCATAGGTCATATTATCTAAAAGAACATTTAAGAGTGCATTCAGGAGCAAGACCATACACATGTCACATCTGTGGGAAATCAAGTGGTACGAAATCTAATCACAATAAGCATGTAAGAATTCATCATGCCCGAGAACCTGTAAATACTGAAAACTAA
Protein Sequence: MDLGIVGNATGASGGAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASSTTSQQTQQLPSPTSVPPVPSSIQSPQNTPQHIQQTTAHVSAQSPYPIGPIFECPPIGTMMPPQFASFSYQQFVNNGTMMIPQYAMAPQTNQMMQMLYNPYGMYQQQQIPTVQMISPVAAIPNTTRIRPVVTMAGETNNRTTITVPVNSSEPKQILPEILPEPEVENEQDLPDINFPASPEVANENTSMQQDGNENSRIQIEHRGQQIQNPTIQDQSSVQHEYNSIPRSLTIACNIENEDDDNAESVLPDIDERETAHIVASVVQCKPTHYEEQSEIRRFDQEYKNDTSKLNLETQDVLGNTIAIEKEKLEGEKSSDEKDKSENESVPSQVPSTEMTKDTAQPEVEQLEQLLITIMESEFNSASTKEHDVQKDEEGKESMEESASVHADEEITPNIIDVISNSHSSDIKECNIEMEITEEPKICVEDKSDKSYILYHYKDSLSAPPSPAIRKKSTRTYSVRSEFGSNENLSVYPVGFDATTLQDEEDDDEKNMTEDNFDEADMEIEAIPSPHTPFMKYGESADGVRSHTPLSAISGISVLRVRKDLSKPCSPASAHSFCHIDGDSLSHDDESNDLREITMEKDPISCPQIEEELKVDKYEENVCENVEKKGNNSNHVYHQSVITEHVSLFPPIHSQQPVLIQDSYPLPNNKNHNLLNLSESINPTTSTESKNYHCSKSIIQKQSMELLNINEDAHAGPMNVFEFDGLQILVPSTFISESSQKAVSATSQQSMASSEGGAGIDEEVKSVNMRADETMPPRGELSEQESNGCTEQSAWQVYMGQESSRMSTSYDLMARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCPEVFDCPKERRVHSTMVHKEPGPSGSRDATEQPEVKDIKLLDGRMNVFDDIFVPGLHVQQMYHQQPLLHQLQPPQPDLAKIETDQKGENLTIPSTVEVSCALCNQRFNSEKALQLHHKRMHIVEVSKRIREQAKCVICNEEFPSVVLFNAHLKIHPLECGQCGKYFYRKQNYKLHMKRHLGIKPFPCTLCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICQCGEIFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRENENVECPICKCIYLRSSLAVHMRVHNGEKPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01514983;
90% Identity: iTF_01514983;
80% Identity: -