Basic Information

Gene Symbol
SALL1
Assembly
GCA_034508555.1
Location
JAVRKA010000011.1:1587581-1589097[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00024 0.0067 17.4 0.3 2 23 168 189 168 189 0.97
2 11 1.5e-05 0.00042 21.2 0.2 1 23 197 219 197 219 0.99
3 11 1.5 42 5.4 0.2 2 23 225 247 224 247 0.86
4 11 0.00011 0.0029 18.5 0.3 3 23 255 275 253 275 0.96
5 11 0.0042 0.12 13.5 9.1 1 23 281 304 281 304 0.98
6 11 9.7 2.7e+02 2.9 0.1 2 11 313 322 312 326 0.84
7 11 1.9e-06 5.3e-05 24.0 0.8 1 23 338 361 338 361 0.97
8 11 0.00059 0.016 16.2 3.1 3 23 371 391 370 391 0.99
9 11 7.6e-06 0.00021 22.1 0.2 1 23 397 419 397 419 0.99
10 11 3.4e-06 9.4e-05 23.2 0.6 1 23 425 447 425 447 0.98
11 11 0.00059 0.016 16.2 2.9 1 23 453 475 453 475 0.98

Sequence Information

Coding Sequence
ATGGAAATCTCCGTAAAGTTTtcagattttcaaaaaatttgtagaatTTGTTTAGAGGAAAAGAATTATATGAAtccaatttttaaatctaaagtACCTGAAATGTTATCATCGTTCACAACGATCAAGATACATGAAGAAGTAGATATTTTACCTCATCTGATATGTTTAGAATGCCTGACGCATGTGAAAAATTGTTACGATTTTAAAAAGCAAtgtgaaaacaataataaaaaattagaacaaGTAGCAAAAGCACGGTTAATCAGCGAATCTTATAATGATTGCGAAGTAAGAGACCAACCTATCTACGCCAAAAAAGATAGCAGAAATAAATCATCGAGTAGCttagataataatttagaaaaaacaaacaagaaaagtatggttattaaaaataagatgatacataagaaaaaaagaacTTTCAATAGAAGTgagttgttaaataaattaagtaaaagtcAAACTGATGAAAACAAAATCATTGAGAAAAATCGAGTGTGCGAAATATGTAATAAAGTTTTGCTGTCTTCGCGTAACTTGGAAAGACATATGCGAATTCACAGTGAAGGGGGTGGAGAACGTTACAGTTGTGAAATTTGCGGTAAAGGATTTAGTTTTTTAAGCGCTCAAGCTGTTCACATGCGTAGGCACAAAGTGAAACCTATTTCATGTACAGTGTgcaataaacaatttttgttgaaattacAACTCGACGTCCATGTTATGAAAGCGCATTCCAACGAACCTAGTATTATATGTGCGTTATGCGGAAAAGGATTTTCTCAGCTAAACAAATTAGAAAGGCACAAACTAACTCATCAGTCGACTCGTCCATATTCATGTAATCTTTGCGATAgtaaatttaaacattcataCTCGTTAAAACATCATCATAAAACAATTCATCAGGGTGTTAAACGCAAAAAGGATGTTTGCAAGATCTGTGGGTTATCCGTTTCGTATTTAAAGCCGCATATATTGGCGAAGCACAGTAATGAACGACCATATAACTGTGAAGAATGCGGAGCGTGTTTTGTAACGAGTTCACTTTTAAATATTCACATCAGATCGAAACATAAAGGTGAATTAGTGTTCAATGCACTGTGCAGTGTTTGCGGTAAACAGTGTCATTCATCGACTGCTTTAGAAATCCACATGCGGACTCACACGAAAGAGAGGCCCTTTAAGTGCAGTACGTGTGGTAAAGGTTTCATGTCTGCAGGAGCATTGAAAGTGCACGTCAGGTCGCACACAGGTGAACGGCCCTATCGATGTGGTACGTGCGGGAAAGCGTTTACTACAAGCCAATTGCTCAAAGTACACAACAGAATTCACACTGGAGAACGACCGTATACATGTAACGTGTGCGAACAAACATTTAGGCAAAGATGTGTTTTGGTGACGCACATGAAACTTCACTGA
Protein Sequence
MEISVKFSDFQKICRICLEEKNYMNPIFKSKVPEMLSSFTTIKIHEEVDILPHLICLECLTHVKNCYDFKKQCENNNKKLEQVAKARLISESYNDCEVRDQPIYAKKDSRNKSSSSLDNNLEKTNKKSMVIKNKMIHKKKRTFNRSELLNKLSKSQTDENKIIEKNRVCEICNKVLLSSRNLERHMRIHSEGGGERYSCEICGKGFSFLSAQAVHMRRHKVKPISCTVCNKQFLLKLQLDVHVMKAHSNEPSIICALCGKGFSQLNKLERHKLTHQSTRPYSCNLCDSKFKHSYSLKHHHKTIHQGVKRKKDVCKICGLSVSYLKPHILAKHSNERPYNCEECGACFVTSSLLNIHIRSKHKGELVFNALCSVCGKQCHSSTALEIHMRTHTKERPFKCSTCGKGFMSAGALKVHVRSHTGERPYRCGTCGKAFTTSQLLKVHNRIHTGERPYTCNVCEQTFRQRCVLVTHMKLH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01530955;
90% Identity
iTF_01530955;
80% Identity
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