Basic Information

Insect: Venustoraphidia nigricollis
Gene Symbol: ZEB2
Assembly: GCA_034508555.1
Location: JAVRKA010000094.1:17281-19616[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.011 0.31 12.1 0.6 1 23 206 228 206 228 0.98

2 10 2.6e-06 7.2e-05 23.6 0.7 1 23 257 279 257 279 0.99

3 10 0.0048 0.13 13.3 1.0 6 23 289 306 286 306 0.96

4 10 6.7e-07 1.9e-05 25.4 0.4 1 23 314 336 314 336 0.98

5 10 0.00059 0.016 16.2 4.8 1 23 342 364 342 365 0.95

6 10 1e-05 0.00028 21.7 0.8 3 23 408 428 407 428 0.98

7 10 5.9e-06 0.00016 22.5 1.9 1 23 434 456 434 456 0.99

8 10 2.1e-06 5.7e-05 23.9 6.0 1 23 462 484 462 484 0.99

9 10 8.6e-05 0.0024 18.8 0.6 3 23 492 512 491 512 0.98

10 10 0.16 4.5 8.5 5.0 1 23 518 540 518 540 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.011	0.31	12.1	0.6	1	23	206	228	206	228	0.98
2	10	2.6e-06	7.2e-05	23.6	0.7	1	23	257	279	257	279	0.99
3	10	0.0048	0.13	13.3	1.0	6	23	289	306	286	306	0.96
4	10	6.7e-07	1.9e-05	25.4	0.4	1	23	314	336	314	336	0.98
5	10	0.00059	0.016	16.2	4.8	1	23	342	364	342	365	0.95
6	10	1e-05	0.00028	21.7	0.8	3	23	408	428	407	428	0.98
7	10	5.9e-06	0.00016	22.5	1.9	1	23	434	456	434	456	0.99
8	10	2.1e-06	5.7e-05	23.9	6.0	1	23	462	484	462	484	0.99
9	10	8.6e-05	0.0024	18.8	0.6	3	23	492	512	491	512	0.98
10	10	0.16	4.5	8.5	5.0	1	23	518	540	518	540	0.98

Sequence Information

Coding Sequence: ATGCCGAACAAAGTTCTAAGATTTGATCGCATCTGCCGAACTTGTTTAAAAGAGACAAAAGTCGAGTCGTTATTGGAAGGGAAGTCTGACGGAGGAGCAATCGTGAGCAACGCAGACATGCTAATGACATGTGCGGCTGTACAGattaaaaagAACGACACTTTACCAAAAGGAATTTGTCGTCTATGTGTCTCTTTGGTAAATCAAGCATACGCGTTCAAAAAGCAATGTGAACGAATCGAAGCTTTTTTACAATCGATATTAACTACAAATCATCGAGAAGCGAAAGGCATAATTATAAAACGAGAAACGTTAGACGAATTGAATCCCGCGGATcgtattaaaattgtaaatgaCTATTTCGGCGGTACACAAAGCACAGAATACGATTGCAGCGGCGTCGTAGAAATAAGCTCAAAAACGTTCGACGAGATCGGTTCGGCATCGCCCGAGGACAGCGTCGACGAAAACATTCAGAAACCGGCACGCGGCGATGAAACAACGAAAAATCGCAACTGGGAAAGCATCGATGCAACCGGAAGCGAAAGAAAGACTGCAGGCAAACTGCGAAAAAAGAGATTGCTCGACGACGAAGCAGCGAATGTAAGGCCCGCTTATAAGTGTTTCGTGTGCGGCAAACTGTTGCCGACAAGGAAGAGCGCGCAGAAGCACATCGATCGGCATTCCAACGCCGAGTGCGGCGAGTGCAGCGAACGATCGGTTCGAGCAGAAGAACCGTACGAACACATGGTTCGAAGGCATCGCTTTTTCAAATGCGACGTCTGTAACAAGGCTTTGAAGCGCAAAGAATCCCTTCAAATTCACATTCGCAGCCATACCGGAGAGCGACCGTTCAGCTGTTTCTGCGGCAACTCTTTCGGCACTCGCGGCAACTTGACGAGACACCAGCTGTCACATCAGGCAGAAAGCAATCGTCCACACAAGTGCCCGTACTGCGAAAAGGCATTCATACAAGCGCCCAACCTCACAGACCACATTCGGAGCCATACCGGGGAGAAGCCTTACGCGTGCGACGATTGTGGGATCTCGTATCGTACGAAGTGCTTGTTGAAATATCATCGCAACAGACACCATTCTGCGTTCTCCGTGCCCGACAAGAAACAAAACGTATCGATTTCGTCCGCCGATTCGAGACTGAAGAAAAATCGTAATCGAGATAAAATCGATAACGCGGGGCGAAGAATGAGAACGAGTGTCCTCTGCAGCGAATGCGGCAAAGTGTTTGCCTCCAAACACACGCTAGaagaacacttgaaaattcatAAAGATCTGAGACCGTTCAAATGCCTGTTTTGCGACAAGACATTCAGACAGCTCAGCGGCCTGAGCAGTCATCAGAGAATACACACGGGCGAAAAACGGTACCGGTGCGAGAGTTGCGACAAGAAGTTTACCCAGAAAACTCATCTGACGACGCACATGAAAACCCACACGGGCGAAAAGAATAACGCGTGTTCGTTCTGCGACCGAAAGTTTGCGCTCAAAGGAAACCTCACGCAGCACCTGCGCGTTCATACGGGCGAAAAGCCCTACGAGTGTTCCGTCTGTCGGAAGGAATTCAATTGTTTGAAGAACATGAAAAAGCACAAACTGACACACGACAACGAACAGACGCTAGTGAACACAGAGCAAAGTTTTGCATAA
Protein Sequence: MPNKVLRFDRICRTCLKETKVESLLEGKSDGGAIVSNADMLMTCAAVQIKKNDTLPKGICRLCVSLVNQAYAFKKQCERIEAFLQSILTTNHREAKGIIIKRETLDELNPADRIKIVNDYFGGTQSTEYDCSGVVEISSKTFDEIGSASPEDSVDENIQKPARGDETTKNRNWESIDATGSERKTAGKLRKKRLLDDEAANVRPAYKCFVCGKLLPTRKSAQKHIDRHSNAECGECSERSVRAEEPYEHMVRRHRFFKCDVCNKALKRKESLQIHIRSHTGERPFSCFCGNSFGTRGNLTRHQLSHQAESNRPHKCPYCEKAFIQAPNLTDHIRSHTGEKPYACDDCGISYRTKCLLKYHRNRHHSAFSVPDKKQNVSISSADSRLKKNRNRDKIDNAGRRMRTSVLCSECGKVFASKHTLEEHLKIHKDLRPFKCLFCDKTFRQLSGLSSHQRIHTGEKRYRCESCDKKFTQKTHLTTHMKTHTGEKNNACSFCDRKFALKGNLTQHLRVHTGEKPYECSVCRKEFNCLKNMKKHKLTHDNEQTLVNTEQSFA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01530924;
90% Identity: -
80% Identity: -