Vnig009089.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Venustoraphidia nigricollis
Gene Symbol
ZEB2
Assembly
GCA_034508555.1
Location
JAVRKA010000021.1:2563779-2567433[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00079 0.022 15.8 0.2 1 23 132 156 132 156 0.92
2 10 0.00038 0.01 16.8 1.1 1 23 162 184 162 184 0.99
3 10 0.0034 0.093 13.8 0.5 2 23 190 211 189 211 0.95
4 10 2.3e-06 6.3e-05 23.8 1.2 1 23 214 236 214 236 0.97
5 10 5.8e-06 0.00016 22.5 1.5 1 23 242 265 242 265 0.96
6 10 4.7e-06 0.00013 22.8 1.3 1 23 297 319 297 319 0.99
7 10 7.3e-05 0.002 19.0 6.4 3 23 330 350 329 350 0.99
8 10 8.6e-05 0.0024 18.8 0.6 1 23 356 379 356 379 0.97
9 10 1.6e-06 4.5e-05 24.2 4.0 3 23 387 407 385 407 0.96
10 10 8.3e-07 2.3e-05 25.1 1.5 1 23 413 435 413 435 0.98

Sequence Information

Coding Sequence
ATGATAAAGACGTGTACTTCCGTTAAGATGAAACTGAACGACGGACTGCCGTCGCATGTTTGTGTCGAATGTATCGACGACATTAAGAAATTTTACGATTTCAAACTTCAATGCCTGCATTCCGACCAGTTGCTTAAAAAAGTGCTTGACGACGACGACGAATTAAAGACTAATTCATCGAAAAGCCTGCCGGTCAACGATACTTTCGCCGACAGCATATTAGacgaaattaaaatagaaaCGAACAACGCGAACGATGATTTTATACGAAACGAGAATGACGACGATAATTATGACGATACACCTATGTCACCTGCACAAGCCGACTTAAAAGAAGAAGAAGCTAGTCCTGTAAAAAATGAAACCGACATTGTACAAGAACCGGAAGAAACCTTTCCGTGcaaagtttgtaataaaatattaggtaGCGAATACTCGCTGTTACGACACATGAAAATGCAAGGTCATGACGGTGATAAGGAGTATACATGCGAACTTTGCaaagaaagtttttataaaatcagaGGTCTTTCCGAACACATGAAGACGCACGGCGTCAAGCCGTTGGTTTGTCCGGTTTGCAAGAAACAATTCATGTTAAAAGTGCAGCTGGAAATCCACCGTAAATTCCACGACAAATTCGCGTGTCGTCAGTGCAATAAAGTGTTCAAAAACGCGAACAATTTAAACCGACACCAGGTGACGCATTCGAATGAAACGCCGTTCCGGTGTTCGCAGTGCGATAAGAGTTTCAAGAGCGAGAGTTACTTGGCGAATCATACCAAATTGGTGCATTACGGTATTAAGAGACGTTCAGTTTGCACTATTTGTGGCATATCGGTTGCGCATATTAAACAACATCTGCTCGTTCATCAAGGATTGAAGCCGTTCAAGTGTACCGATTGTGACGCCTCGTTCATGACGAGCGGTCATTTGAACGCGCATGCGCGGAAGCATTCCGGAGAAGTGCAAATTTACGGCACGCTGTGCACGATTTGCGGCAAGAAGTGCCGACATTCCACGCAGCTTCGAATTCATATGCGGAAACATACGgGCGAAAGACCCCACGTTTGCACGTATTGCAGTAAAGCTTACAAGACAGGTTCGGCGCTGACTGTCCACGTAAGATCGGCACATACCGGCGAACGTCCACATCTCTGCAGCATGTGTAATAAAACCTTCACCACATCGGATACGCTTAAACAACACATACGGACCCACACTGGCGAACGCCCGTTCGTGTGTCAAGTCTGCGGTCGAGGATTCACGCAAAGACACGCCCTCAAGACGCACATGAAAATACATAATTCAGACTGCTAA
Protein Sequence
MIKTCTSVKMKLNDGLPSHVCVECIDDIKKFYDFKLQCLHSDQLLKKVLDDDDELKTNSSKSLPVNDTFADSILDEIKIETNNANDDFIRNENDDDNYDDTPMSPAQADLKEEEASPVKNETDIVQEPEETFPCKVCNKILGSEYSLLRHMKMQGHDGDKEYTCELCKESFYKIRGLSEHMKTHGVKPLVCPVCKKQFMLKVQLEIHRKFHDKFACRQCNKVFKNANNLNRHQVTHSNETPFRCSQCDKSFKSESYLANHTKLVHYGIKRRSVCTICGISVAHIKQHLLVHQGLKPFKCTDCDASFMTSGHLNAHARKHSGEVQIYGTLCTICGKKCRHSTQLRIHMRKHTGERPHVCTYCSKAYKTGSALTVHVRSAHTGERPHLCSMCNKTFTTSDTLKQHIRTHTGERPFVCQVCGRGFTQRHALKTHMKIHNSDC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01530840;
90% Identity
iTF_01530840;
80% Identity
-