Vnig000928.1
Basic Information
- Insect
- Venustoraphidia nigricollis
- Gene Symbol
- ZFY
- Assembly
- GCA_034508555.1
- Location
- JAVRKA010000002.1:4677091-4679310[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 1.7 46 5.3 0.5 1 11 46 56 46 66 0.90 2 19 0.016 0.43 11.7 1.3 1 23 72 95 72 95 0.97 3 19 0.33 9 7.5 2.4 1 23 101 120 101 120 0.93 4 19 0.00058 0.016 16.2 0.6 1 21 126 146 126 149 0.90 5 19 5.5e-05 0.0015 19.4 0.6 1 23 154 177 154 177 0.93 6 19 5.1e-05 0.0014 19.5 0.9 1 23 210 232 210 232 0.98 7 19 0.33 8.9 7.5 1.9 2 23 239 260 238 260 0.96 8 19 2.6e-08 7.2e-07 29.9 2.7 1 23 266 288 266 288 0.99 9 19 0.47 13 7.0 1.0 1 23 294 317 294 317 0.95 10 19 6 1.7e+02 3.5 0.6 1 12 402 413 402 423 0.88 11 19 1.4 38 5.6 5.2 3 23 430 450 428 450 0.94 12 19 6.2 1.7e+02 3.5 0.8 2 12 456 466 455 474 0.80 13 19 1.9e-05 0.00054 20.8 1.0 1 23 481 504 481 504 0.96 14 19 0.0013 0.035 15.1 6.8 1 23 509 532 509 532 0.95 15 19 0.61 17 6.7 0.5 1 23 541 562 541 562 0.95 16 19 0.00094 0.026 15.5 0.2 1 23 565 587 565 587 0.98 17 19 3.7e-05 0.001 19.9 1.5 1 23 593 615 593 615 0.98 18 19 5.2e-07 1.4e-05 25.8 1.7 1 23 621 643 621 643 0.98 19 19 0.0047 0.13 13.3 1.9 1 23 649 671 649 671 0.98
Sequence Information
- Coding Sequence
- ATGAAGAAGGAAGACgaggttttaataaaatctgcaaTGGAAAAAGCGAAGAAGCGCAAATGTAAAACGaagataaacaatgttaaaGGTTTAAGATTTAAACTAAAAGCGTTGGTTCCTATATCGGACGGCAAATATCAATGTGAaatttgtaatgaaatattCGACAAAATTAAACGTTACCATTATCTCAAACACGAAATTTCCCGACCCTTTAGCTGTGATGCGTGCGAGAAAACTTTTCAGTTGAACTGGCAGTTGAATAATCATAAAAAGAAAATGCATTTGAACCCGCAGGTTTATAAGTGCGACATCTGTAACAAAATGGTCAAGGACATGAAATCGCATCAGAGAACTCACGTCGATGTGTTTCCTTATAAATGCGAGAGTTGCAGCAAGGAGTTTCGTGTCAAGAGTCAGTTGAAAGTTCACAACGAGGCGGCACACTCTGATATCAGACACACGTGCGCCATTTGTGGCAAATCGTACACCAGTTTAGGGAATTTGCGCGATCACGAGAAAGCTTCGCACGATCCTTATTACGATCCGCCAAAATTCAAGTGCGAAATTTGCGGGAACGAAGTGCCGAACCGGTTCAAAGCGAAGCACATGAAACGCCATACGGGTTTCACGTGCGACGTTTGCGGAAAATTTGTCACTTCTAAAAAGAGTTTACAGCTGCATCTATTGCGTCACAAGGGTGAGAAACCGTTGTCTTGTAACGTTTGCGGTAATAGTTTTCTTCAGTTGAACACGTTGAAGTGTCACATGCGAATACATGACGGGGTTAAACCGTATAAGTGTGGGGAGTGTGGGAAATGTTTTCGGCAGAGCAGCAGtcttaaaatacatattagaaTGCATACAGGAGAGCGACCTTATTCTTGTCAACTTTGTGCTGACGCGTTCGTAAGCAAAACGTTATTGAAcactcattttaaaaacaaacacggATTCAGGCTTGTAATTAGTGGGTATCTTTTCAGGCCGTTTGTTTTGAAGACTGAAATAACAGATGAGGAAAACGCATGCGCAGACCGCGGGAGTGATAATCTATGCATACTGCGCAATCTGTTGTTATCGTCTGAAAGTGAGTTAACTGTTAAAAAAGACAAGGCCGTTCGAAAAGAGAAGGCGTCGTCGAAAATCGAACTGGATTTAAAAGTGATTTCGAGATCGTTTGTTCCGGTGAAGAATGATAAATACAAATGTCGGTTCTGCGACGAGATATTCGATAAACCGCAGCCGGATCATTATTTGAAACATGAGGAGAGTCGACCTTTCGGCTGCGAGGTCTGCGGCAAAAAGTTCCTTTTAAGTTGTCACTTAAAAAGACATAAGTATTACCATAAAACCCAGCTTTCTAAGTGTGAAGTATGTAACAAAACTGTCAAACATATAAAAAGTCACCAGATCCTACACAATATGGAATCGTTTCGCTATAAATGCGAACTTTGCGGTAAAGAATTCCGTTTCAAATCGGAATTAAGTGCTCACAGCGAAACTTATCATAGCGATATAAAACATGCTTGCAATACTTGCGGGAAAATATTTCGTCATCGGTGCAGTTTAAGAGCGCACGTGAAAAGAACGCACAATCCTTTTTATGTTGCGAAAACTTTTAAGTGCGAAGTTTGTTCTGAAAATGTGTCGACCAGCAATAGGGCAAAGCATATGGATAGGCATCTGGGCTTTACTTGCGACGTTTGCGGAAAATGGGTCACCAGTTTGGGAAGCTTAAAGAAACACATGCTGCTGCATACGGGGGAAAAACCGTTTAATTGTGAAACTTGCGCGAAAAGTTTCTCGAAACGGAGCACTTTGGTGCTTCATCTTAGAACACACACCGGTGTTAAACCCTACGAGTGCAAGGAATGTGATAAGAAATTCACGCAAAGAACTAGTTTAGTTGTTCATATGAGATATCACAGCGGGGAAAGACCGTACGAATGTCATTTGTGTAGTAAAGCGTTTGTTAGCAAAACGATTTTAGATACTCATATCAAAAAGCATGGTTTTTAA
- Protein Sequence
- MKKEDEVLIKSAMEKAKKRKCKTKINNVKGLRFKLKALVPISDGKYQCEICNEIFDKIKRYHYLKHEISRPFSCDACEKTFQLNWQLNNHKKKMHLNPQVYKCDICNKMVKDMKSHQRTHVDVFPYKCESCSKEFRVKSQLKVHNEAAHSDIRHTCAICGKSYTSLGNLRDHEKASHDPYYDPPKFKCEICGNEVPNRFKAKHMKRHTGFTCDVCGKFVTSKKSLQLHLLRHKGEKPLSCNVCGNSFLQLNTLKCHMRIHDGVKPYKCGECGKCFRQSSSLKIHIRMHTGERPYSCQLCADAFVSKTLLNTHFKNKHGFRLVISGYLFRPFVLKTEITDEENACADRGSDNLCILRNLLLSSESELTVKKDKAVRKEKASSKIELDLKVISRSFVPVKNDKYKCRFCDEIFDKPQPDHYLKHEESRPFGCEVCGKKFLLSCHLKRHKYYHKTQLSKCEVCNKTVKHIKSHQILHNMESFRYKCELCGKEFRFKSELSAHSETYHSDIKHACNTCGKIFRHRCSLRAHVKRTHNPFYVAKTFKCEVCSENVSTSNRAKHMDRHLGFTCDVCGKWVTSLGSLKKHMLLHTGEKPFNCETCAKSFSKRSTLVLHLRTHTGVKPYECKECDKKFTQRTSLVVHMRYHSGERPYECHLCSKAFVSKTILDTHIKKHGF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -