Vnig003126.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Venustoraphidia nigricollis
Gene Symbol
zfh1
Assembly
GCA_034508555.1
Location
JAVRKA010000005.1:12628288-12638168[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.085 2.3 9.4 0.6 1 22 196 217 196 220 0.90
2 22 0.0049 0.14 13.3 0.3 2 23 228 248 227 248 0.96
3 22 6.9e-05 0.0019 19.1 4.6 1 23 254 276 254 276 0.98
4 22 0.00042 0.011 16.6 2.2 1 23 282 304 282 304 0.97
5 22 3.1e-05 0.00086 20.2 2.1 1 23 310 332 310 332 0.98
6 22 0.00011 0.0031 18.4 0.2 1 23 348 370 348 370 0.98
7 22 0.00013 0.0035 18.3 1.7 3 23 377 397 375 397 0.96
8 22 0.0012 0.034 15.2 0.2 1 23 403 425 403 425 0.97
9 22 2.8e-06 7.8e-05 23.5 3.4 1 23 431 453 431 453 0.99
10 22 0.0018 0.049 14.7 1.5 1 23 459 481 459 481 0.98
11 22 0.00012 0.0034 18.3 2.8 1 23 487 509 487 509 0.99
12 22 0.0077 0.21 12.7 1.1 1 22 771 792 771 795 0.91
13 22 6.2e-05 0.0017 19.3 0.6 2 23 803 823 802 823 0.96
14 22 4e-05 0.0011 19.9 2.5 1 23 829 851 829 851 0.98
15 22 1.9e-05 0.00052 20.9 0.5 1 23 857 879 857 879 0.99
16 22 0.00058 0.016 16.2 0.9 1 23 885 907 885 907 0.97
17 22 1.1e-05 0.00032 21.6 2.1 1 23 924 946 924 946 0.98
18 22 0.0066 0.18 12.9 1.8 1 23 951 973 951 973 0.96
19 22 0.00076 0.021 15.8 0.6 1 23 979 1001 979 1001 0.98
20 22 8.6e-06 0.00024 22.0 4.4 1 23 1007 1029 1007 1029 0.98
21 22 2.2e-05 0.00061 20.7 5.4 1 23 1035 1057 1035 1057 0.98
22 22 5.3e-05 0.0015 19.5 1.3 1 23 1063 1085 1063 1085 0.98

Sequence Information

Coding Sequence
atgaatttgtCTCTTTCTTATGATAAGATTTGCCGAGCTTGCTTAACCGATGGAAATGGTGAACTAAAATCGATGTTTGATGAAAGTCAAACTGAATTTTCAATTCGTCTTTCGGAAATGTTTATGGAGTGCACTCCTGTACATGTATCAAAAGACGACGGCTATCCGTGGAATTTATGTACTAGTTGCGTACAACAATTGAATCTTTCGTATCAGTTTCGCGAAAAGTGCGTTAAATCAGATTTCACATTACAGTGGTATGGCCAGTGTAATACAATACCACGTGATATAAAGTCTGAACAATCGGAAGAAACTGGAGACtgtaaaataagtttgtttGTTGAAGTAAAGACTGAAGATGACAATAACGTCGATAGTTCTAGTGATTCAATCGAAACTGTAACGAATACTCGAGATACTCGACAGCGGAAATGCAAAACTAAACGCGATAAAGAACAAAACAATGCAGAAATAGTCGATAAAGATGAAGGAAAGTCTGCGATATCTCTCAAGCGTGTTCGTAACCGCAAGACAGAAAAAAAGTCTAAAACTAACGAAAAGGAACCGGTGATCACCGGTCCACCATACACTTGTCAGAAATGTGACGTCACGTTCGAAATGGATCGGGAGCTGGCGACGCACTATCAATCTAAGGAGCATAAGAATTACAGGACCAAAGTTCCCTGTACGGTATGCGGCAAAACGTTCTTCGAAGTTCGACTGAAATACCACATGCGTATTCACACCAACGAACGATCATTCGTGTGCGATGTGTGTGGTAAAGGCTTCAACCATAACCATTACCTGAAAACGCATAAAATGACTCACACAGGACAACGACCGCACGTGTGTCCGATTTGCAACCAGGGTTTCATTCAGAAGTGCTTGTTGGATAAACATATCAGAAATCACACAGGCGAAAGGCCCTTTTCTTGCAACATTTGTCAAAAAACATTCAAGATACAATGGTCGCTCAAATTGCACCAGAAAACGCACGAACCCAAAACTGccgacgataaacaaaaagaaacatCCAAAAGATATCCGTGTGAAATATGTCAGAAGACGTTATCTTCAAAGGAGACTTTGTTTGCCCACGTAAAGATTCACGGTGACAAAACGCATTTGTGCAGTCAATGCGGCAAAGGTTTCATTAGCTCCGCACTGCTTAAGTCTCACTACAAAACACATACGAGGGAGAAGCCCTACAAGTGCAACATGTGCGGGAGGGCGTTTGCACAGCTCGGAGTAATGAAAACACACAAACTTGTACACACagGCGAGAAGCCTTACTCGTGTTCTATTTGCGGTAAGAAGTTCACCCAGCGGGCTCATATTCAGTATCATATGCGGACACACAGCGGGGAGAAGCCCTATTCGTGCACCGTGTGTGGAAAGTGCTTCGCGGCGAACCAAATTCTGAAGACACACATAAGACAGCACTCGGGGGAACAGCCCTATAGGTGCTCTGTTTGCAACAAGGGCTTCTATGATCCTTATAGCATGAAGAAACACAAAAAAAGACATGGATGTAATAATGTCACGGTTGACGCCGCCGATACAGGCTTTGCTGTGGATAGCATGGATgAGTCAAAGAAACGTCGTATAAACAACGGCACTCAACAGCCTCGATTCTTGGCTGTATTTTTGAGGTTAAAATTCTGTCAACATAACTTgacagtatttttgaaaataatgaatttgtCTCTTTCTTATGATAAGATTTGCCGAGCTTGTTTAACGGATGGAAATGATAGTGAACTAAAATCGATGTTTGATGAAAGTCAAACTGAATTTTCAATTCGTCTTTCGGAAATGTTTATGGAGTGCACTCCTGTACATGTATCAAAAGACGACGGTTATCCATGGAATTTATGCACTAGTTGCGTAAAACAATTGAATCTTTCGTATCAGTTTCGCGAAAAGTGCGTTAAATCAGATTTCACATTACAGTGGTATGGCCAGTGTAATACAATACCACGTGATATAAAGTCTGAACAATCGGAAGAACCTGAagactgtaaaataaatttgtttgttgaaGTAAAAACTGAAGACGACAATATCGTCGATAGCTTTAGTGACTCCATCGAAACTGTACCGAATACTCGAAATACTCGACAGCGAAAATGTAAAAGAAAACACGATGAAGagcctaaaaacaaaaaacgcaCAAGAAGTAAAAACAGTgtagaaacagttgaaaaagaTGAAGAAAAGTCAACGATATCCCACAAGCGTGTTCGTAACCGCAAGGCAGAAGAGAAAGGCAAACCTGGCCGAAAGAAACGGGTAATCACCGGTCCACCTTACACTTGTCAGAAATGTAACATTACTTTTGAAACGAAGCTAGAATTGGCGACGCATTATGAATCTAAACAACACAAGCATCACAGAATACAAGTTCCATGCACGGTGTGCGGCAAAACGTTCAGCAAACCCCGACTGAAGAATCACATGAGAACACACACAAAAGAACGACCGTTTGTTTGCGATGTGTGCGGCAAAGATTTCAGTCTGAACTGCAATTTGCGTCGTCACAAAATGACACACACCGGACAGCGGCCGTACGTTTGTCAGATTTGCAACCGGGGCTTCATCCAGAGCACAATGTTGATCAATCATACAAGAACGCATACTGGCGAGAGGCCGTTCGCTTGCAACGCTTGCGGGAAGACGTTCAAGATATCTCTGTCGCTCAAATTGCACCAGAAAACACACGAACCCAAAACAGCCGAAGAAAAACGCAAAGAAACCACCGATAGAATATACGCCTGCGAGATATGCCAAAAGTCTTTTTCCTCGAAAAACTGTCTGAGTGCACATGTCAGGACGCACGGCGACAAGAAATATCTGTGCAGTCGATGTGGCAAAGGATTCGTTAGCTACGCTCTGCTACATTCGCACAACAAGACGCATACGGGGGAGAAGCCCTACAAATGCGATGCGTGCGGGAAGGCGTTTACGCATGTCGGCGCCATGAAAACGCATCAGCTTCTGCACACAGGGGAGAAGCCGTTTTCTTGTTCTCTGTGCGGCAAGAAGTTCACCCAACGACCTCATCTTAAGTACCATTTGCGAACACACAGCGGGGAGAAGCCCTATTCGTGCTCCGTATGTGGAAAGTGCTTCTCGTTGAATTGCAACCTCAAGATACACATGAGACAGCATTCTGGGGAACAGCCTTACAGGTGCGCCGTTTGCAATAAAGGCTTTTATGATTCTAGCAGCATGAAGAAACATCAAAAAGGGCACGGATTTAACGCCGTCGTTGGCACCGTCGAACCATTTTTAATTCAAGACGGTATGACatcgtaa
Protein Sequence
MNLSLSYDKICRACLTDGNGELKSMFDESQTEFSIRLSEMFMECTPVHVSKDDGYPWNLCTSCVQQLNLSYQFREKCVKSDFTLQWYGQCNTIPRDIKSEQSEETGDCKISLFVEVKTEDDNNVDSSSDSIETVTNTRDTRQRKCKTKRDKEQNNAEIVDKDEGKSAISLKRVRNRKTEKKSKTNEKEPVITGPPYTCQKCDVTFEMDRELATHYQSKEHKNYRTKVPCTVCGKTFFEVRLKYHMRIHTNERSFVCDVCGKGFNHNHYLKTHKMTHTGQRPHVCPICNQGFIQKCLLDKHIRNHTGERPFSCNICQKTFKIQWSLKLHQKTHEPKTADDKQKETSKRYPCEICQKTLSSKETLFAHVKIHGDKTHLCSQCGKGFISSALLKSHYKTHTREKPYKCNMCGRAFAQLGVMKTHKLVHTGEKPYSCSICGKKFTQRAHIQYHMRTHSGEKPYSCTVCGKCFAANQILKTHIRQHSGEQPYRCSVCNKGFYDPYSMKKHKKRHGCNNVTVDAADTGFAVDSMDESKKRRINNGTQQPRFLAVFLRLKFCQHNLTVFLKIMNLSLSYDKICRACLTDGNDSELKSMFDESQTEFSIRLSEMFMECTPVHVSKDDGYPWNLCTSCVKQLNLSYQFREKCVKSDFTLQWYGQCNTIPRDIKSEQSEEPEDCKINLFVEVKTEDDNIVDSFSDSIETVPNTRNTRQRKCKRKHDEEPKNKKRTRSKNSVETVEKDEEKSTISHKRVRNRKAEEKGKPGRKKRVITGPPYTCQKCNITFETKLELATHYESKQHKHHRIQVPCTVCGKTFSKPRLKNHMRTHTKERPFVCDVCGKDFSLNCNLRRHKMTHTGQRPYVCQICNRGFIQSTMLINHTRTHTGERPFACNACGKTFKISLSLKLHQKTHEPKTAEEKRKETTDRIYACEICQKSFSSKNCLSAHVRTHGDKKYLCSRCGKGFVSYALLHSHNKTHTGEKPYKCDACGKAFTHVGAMKTHQLLHTGEKPFSCSLCGKKFTQRPHLKYHLRTHSGEKPYSCSVCGKCFSLNCNLKIHMRQHSGEQPYRCAVCNKGFYDSSSMKKHQKGHGFNAVVGTVEPFLIQDGMTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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