Basic Information

Gene Symbol
-
Assembly
GCA_960531455.1
Location
OY482674.1:42191082-42195582[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.24 32 6.6 5.4 2 23 221 243 221 244 0.94
2 17 1.9 2.6e+02 3.7 4.1 2 23 292 314 291 314 0.95
3 17 0.00026 0.034 15.9 0.2 2 23 329 351 329 351 0.94
4 17 0.0005 0.067 15.0 0.1 1 20 361 380 361 381 0.96
5 17 0.0011 0.14 14.0 4.3 1 21 445 465 445 466 0.95
6 17 5.7 7.5e+02 2.2 5.2 1 23 511 534 511 534 0.93
7 17 0.36 47 6.0 0.7 1 11 586 596 586 600 0.91
8 17 5.2e-06 0.00068 21.3 2.2 3 23 633 654 632 654 0.97
9 17 3.5 4.7e+02 2.9 1.9 1 22 708 729 708 729 0.94
10 17 0.082 11 8.0 1.7 3 23 760 781 759 781 0.89
11 17 4.9 6.5e+02 2.5 1.5 3 20 837 854 835 856 0.91
12 17 4.4 5.8e+02 2.6 0.0 2 23 1067 1090 1066 1090 0.90
13 17 0.0004 0.053 15.3 0.2 1 23 1226 1249 1226 1249 0.95
14 17 4 5.3e+02 2.7 2.7 1 23 1296 1319 1296 1319 0.96
15 17 1.1 1.5e+02 4.5 2.6 1 23 1325 1348 1325 1348 0.96
16 17 0.98 1.3e+02 4.7 1.0 3 23 1358 1378 1357 1378 0.93
17 17 0.0016 0.22 13.4 1.4 1 23 1385 1408 1385 1408 0.97

Sequence Information

Coding Sequence
ATGGAGAACTCATCGTCATTGTCGCAAGACGAATCAGGATCAGGCGATGAAAATATAGGTATTGCGTATACTAAAAATATAACACTTGGAAAGCGTGCAGCGAACTATGATGATTCACAAACTGATAGCGATGAAGATGCAAATGCAAAGATTTGGAAACCTGAAACACATCTGGTAGAAGACGACGATGAATCAAAGTCCACAACTGAAGATATTGACGATAGCGACGATGATCATGAACCTCTTGAGGCAAATATGCAACCGGAAACTGTATTAATGGAAGATGAAGACAATTATATTGACTTCAATTCTGATGATGAATGTAGGCCTGCGAAAATTTTACAACGTAAAAGGAAACCTCTAGTAGAAagtgatgatgacgatgatggtGAGGAAGATTCTAATTCGGTTCCGAACCGCAACACAGATAACTCAAAAAGAAAGTACAGACCAAAAAAAAGATGTGAAACAGATAGTGAAAACGATGATAATTCCGATAATACGAATAATGATGATGAAAACTATGAAACAGAATCTGAGAATAGTGTGGATGATGAGCCCGAAGCAAAGGGGGCATGCCCAGTGCTACCAGAATTGAACACAAAGAAAAAGGCGTACATAAAGAGTGCCAATTTTATTTACCGCAATTTCGTTGTGCGACAATGTCCAATGTGTGAATTTGAGTTTAATTCAGCACATTGCTGGAAAAAGCATATTAATTTCATGCATCATCTTGAAAAACCCGAACAATTGCAATTCAAATATAACGAACGTGGGGCCAAATGCAAATCGTGCACATTTCAAACCGCCTCGCCCAGTTTCAATAAGTTACTAGATCATGAAATAACGCATATGCCCAACAGTCATTACCTAAAGTGTAAGCTTTGCGATTGGAAAACTAAAACACACACAAGCATGAATTTTCATTTGCGTTCACAACACGCCGAAACTATTGATGTAGAATCGAAGAGCGAAGAGCTCAGAGTTTGTGTGTATTGCAATCAGGAATTCGCATCACAATGGTATTTACGTCGACACATGATTCAGGAACATGAGAAGAAAATAAGTGACAGAACCTTCTTCAAATGCCTGGAATGTGGGCAGGAGTTCAACTCTAATGCAAGTTTACGTGCTCATGTATATGAGAAATTCGAGAAGAATACGCCACAAGAATTGGGTTTCGAATTGATGCCGACTGAGGGCGAAAAATCAGCTTATCTAAAATGCCTACAATGTACGCAAACTTTTCGGCGAATAGAGAAGAGGGTTACGAAAATTAATTTAAGAGAACACTATATGTTGCATTTGGGCGAAGCGTCAGGCACGAATGCTTATAAATGTAAATATTGCTCGTTAAGTTTTCGCCGGTATGATAATATGCGAATGCATATTTGTAAAAAGTTGGGTGAAACATTAGAAAAGCATGTCGCTGATATAAGTGCGGGTGGCTTAGCAAAGTCTCAAGACGCAAAACAAAAGAGTCCATTCGAGCGGGCGACATCTAAGAGGGAATACATGAAAAACATACGACACGTTTGCTTGAAATGCGGCATCTCATTTGGAAAGATGTCCTTTTGCAAAAAGCATATGTTTTCAAGTCATGGCATGGACAAAGCGCCGGGGTTGGATTTTCGGAAGATTGGTCATCAGGATTCAACTGAAATATACGAGTGCACAGTGTGCGAAGAGTTTACATGTGATTTTGATTTGAACACAATGTTGGTACATGCACGTACCCATACAGTGTATGATCCATTTCAATGTAAGCTTTGTCAAAAGACTTTTGCCTACGATACAGATATACCAGGACATCATTGTGTCGACGATAAGGATGCAAATATTGCGAATGAAACGCGCCAATCTAATGAGGGCATGCTTACAAATATGGAAAACCTTTGTCCCAAATGCGGTCAGACATATTCGACAAATTCCACTTTAACCAGACACATGCATAGAGTTCATGCCATGAACAAGCCTCACGGACTTGGTTTCTCAGCGTTCGAAACAGCTGGGGGAGCTATAACCATATATAGTTGCACCGCATGTGCTGACTTCACTGCCGTTGAGGAAGATATGAAAGCTATGTTCGAACATGCTCTAAAGCATATGCCCTACAAAAGCTATCGGTGCACCTTATGCAGTGAACTATTTCAGCTCAAAGAAGAAGTCAAACAACATCGATGCACACAACGACCGGCAATTTTGAAAAGCACTCCGGTCGCTGTGACATTTgcgaaaagtgaaaataaaaTACGTTTAAATAAAATGGGACGAATTTGTCCAAAATGTGGTAAGAGATTTGCGAAAACGTCTGTATGCAAAGTCCATATGACCAACATACATGGCATGGATACGCCCAGTGGACTTGGTTTTGTGGTAATGGAAACTTCGAATGTCCTTCAAAATATATACCGTTGCACGCAATGCACAAACTATACGCTTGACCAGCCCGATGTCAGCACAATGTTGGAGCATGCGCGAGAACATTTTCCATTCGATGGTTTTTGGTGTAAATTGTGCGAACAGAGTTTCCGTCTAAAGACCGAAGCGAGCAATCATCGCTGCGATGATGCTGGTGAAATGGAAAACTCATCACAGGCAAAATGTGTAAAATCATTCGAAAAATGTATGAGAAAACTGTGTCCGGAATGTAATAATGAAATGCCTTCGGTAAAAACCTGGCGTTGGCACATGATAAAATATCATGAATTTAACACACTCGAAGGACTAAAAATGGCACAAACAAATGCCAATTTACTAGAGTGTCGCATATGTCAGATGCATATAACCCATAAGAGAAGATACGAACATCGCTTTCTACATTTACCTTATAAGCCATATCAATGTAAATTCTGCAATGAATTATTCATAGAAATGGATAAGGCGAAACAGCATTGTAATGAATGTAAATTGGTGCCAGCCGAATTGCCCGAGCGTAATGAAAAAAAGAAGGAAACGCCTGTAAAACAGAAACCAGGAAATTCAGCGAATAGCTCGAAGGTATACAATGAGCATGAGAAAAGCTCAGATGAAGCAGACTGCGAGGTGATCTCAACCAAGGAAACGGGAAAGCCGCAAAGCAGATCAAAACAAGGTCAAGTAAAAAAGCAGAAGAGCGAAAATGAAACCTCAAATAAGATTAAAGGCATCAGCGTTGTACTCACCGATGATAATGATTATGCGAAATTCGTACGCATTAGCTGCCCCCTCTGCCCCGATACGGAATTCGAAACAAATGTAGCGCTAGCGGCTCACTTCCAAGAGGAGCACAATAATTTCAGCGAACACTTTATCATACACAATACAAATGCAGCCAATTGTAAAGCGTGTAATAAATACTTCAATGTTGTTTACAAGAAAACGCTAGTGCGCCATTATTTGGGCGAAATCAATGCTACATGCTATTGTTGCCGACTGTGCGATAAGAACTTCCTCTACTTCAACACAATGCGCACACATTTGCTCGACGAACATGAAGCTATCATAGCAGGGCAATCGCAAAGCAGCATCACTAACGCAGCCGTCACAGCGGGCAGCTCGTCGACGATTGTGCGCGATGGTGGCGCAGATCCACTCACGGTAACTGCCATTGATATATCGAAAGTTTCACGCACTACAATGGCCATTCGTACGCATAAGACGGCGGTGTTTAATGAATTTAATGCATACATTGCGTACGCTTGTCCTGAATGTAATGAGTCCTTCGAAACATCCGAGCAATGGCATTTACATATAAATGGCCAACATGATTTCTTCGATCAGCAACAGCTGAATATCGAAGCAACAGCCGATGGTTATAAACGTTGTAAACAATGTAATGTTAATATATCTGGTGGCATATTGGCGGAACAACGTCACAAGCTAACACACATGAAAcataaatcatttatttgtaCACTCTGTTTGCATCGTTCCACAACTTTGGGTGTGCTGACTCAACACTTTCGACGACGTCATTTTGCCAAGGGTGCATTTAAATGTCCACTATGCACATGCATACTCAGCACATCATGCGAGCAAATTGAACATATTAAGAATGAACATGACGAAAGTGAATATCCACATACGCTTTGTCGCGTTTGCTTTAGTAATTTTAGTTCGTTGAAAGCATTGCAAACGCACAAAGAGTTACACAATCCCAATCGTGTGGTATTCCAATGCACATATTGCGAACGCTTATATAAATATAAGCGAGAATTGGTCCTACATATACGTGCTAAGCATCCGGGGCAGGAGGAGCCCACTGATGAGAATgagtaa
Protein Sequence
MENSSSLSQDESGSGDENIGIAYTKNITLGKRAANYDDSQTDSDEDANAKIWKPETHLVEDDDESKSTTEDIDDSDDDHEPLEANMQPETVLMEDEDNYIDFNSDDECRPAKILQRKRKPLVESDDDDDGEEDSNSVPNRNTDNSKRKYRPKKRCETDSENDDNSDNTNNDDENYETESENSVDDEPEAKGACPVLPELNTKKKAYIKSANFIYRNFVVRQCPMCEFEFNSAHCWKKHINFMHHLEKPEQLQFKYNERGAKCKSCTFQTASPSFNKLLDHEITHMPNSHYLKCKLCDWKTKTHTSMNFHLRSQHAETIDVESKSEELRVCVYCNQEFASQWYLRRHMIQEHEKKISDRTFFKCLECGQEFNSNASLRAHVYEKFEKNTPQELGFELMPTEGEKSAYLKCLQCTQTFRRIEKRVTKINLREHYMLHLGEASGTNAYKCKYCSLSFRRYDNMRMHICKKLGETLEKHVADISAGGLAKSQDAKQKSPFERATSKREYMKNIRHVCLKCGISFGKMSFCKKHMFSSHGMDKAPGLDFRKIGHQDSTEIYECTVCEEFTCDFDLNTMLVHARTHTVYDPFQCKLCQKTFAYDTDIPGHHCVDDKDANIANETRQSNEGMLTNMENLCPKCGQTYSTNSTLTRHMHRVHAMNKPHGLGFSAFETAGGAITIYSCTACADFTAVEEDMKAMFEHALKHMPYKSYRCTLCSELFQLKEEVKQHRCTQRPAILKSTPVAVTFAKSENKIRLNKMGRICPKCGKRFAKTSVCKVHMTNIHGMDTPSGLGFVVMETSNVLQNIYRCTQCTNYTLDQPDVSTMLEHAREHFPFDGFWCKLCEQSFRLKTEASNHRCDDAGEMENSSQAKCVKSFEKCMRKLCPECNNEMPSVKTWRWHMIKYHEFNTLEGLKMAQTNANLLECRICQMHITHKRRYEHRFLHLPYKPYQCKFCNELFIEMDKAKQHCNECKLVPAELPERNEKKKETPVKQKPGNSANSSKVYNEHEKSSDEADCEVISTKETGKPQSRSKQGQVKKQKSENETSNKIKGISVVLTDDNDYAKFVRISCPLCPDTEFETNVALAAHFQEEHNNFSEHFIIHNTNAANCKACNKYFNVVYKKTLVRHYLGEINATCYCCRLCDKNFLYFNTMRTHLLDEHEAIIAGQSQSSITNAAVTAGSSSTIVRDGGADPLTVTAIDISKVSRTTMAIRTHKTAVFNEFNAYIAYACPECNESFETSEQWHLHINGQHDFFDQQQLNIEATADGYKRCKQCNVNISGGILAEQRHKLTHMKHKSFICTLCLHRSTTLGVLTQHFRRRHFAKGAFKCPLCTCILSTSCEQIEHIKNEHDESEYPHTLCRVCFSNFSSLKALQTHKELHNPNRVVFQCTYCERLYKYKRELVLHIRAKHPGQEEPTDENE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-