Tjac010414.1
Basic Information
- Insect
- Tyria jacobaeae
- Gene Symbol
- Bcl11a
- Assembly
- GCA_947561695.1
- Location
- OX387226.1:4597554-4610355[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.011 0.85 10.7 1.8 2 23 74 95 73 95 0.96 2 12 0.013 1 10.5 1.3 2 23 102 124 101 124 0.95 3 12 0.25 20 6.4 1.7 2 23 132 154 131 154 0.89 4 12 6.8e-06 0.00054 20.8 1.3 1 23 160 182 160 182 0.96 5 12 1.9e-07 1.5e-05 25.7 0.6 1 23 188 210 188 210 0.97 6 12 0.019 1.5 9.9 1.8 1 21 216 236 216 237 0.93 7 12 0.34 27 6.0 3.9 1 19 255 273 255 278 0.92 8 12 0.00095 0.077 14.0 2.2 1 23 591 613 591 613 0.96 9 12 2.4e-05 0.0019 19.0 1.4 1 23 620 642 620 642 0.97 10 12 0.17 13 6.9 5.1 1 23 650 673 650 673 0.96 11 12 0.00043 0.035 15.1 2.7 1 23 679 703 679 703 0.96 12 12 0.048 3.9 8.6 6.1 1 22 709 730 709 730 0.96
Sequence Information
- Coding Sequence
- ATGGATTCTAATTTACCATTTTATAGTTTACCTTTTGTAGATTCTGATGCAACCGATATAGAATTTAACAAGTTGAAGCCTCAGGAGTCAGTTTATGATGTTCTTAATCCAGCTTTACCATCAAGTAGTGCCCTACTTGGGTCAGATGATGTCCTAGCCCAGTTTCTGTCTGGTGATGAACCACTGGAAGAGCCAGACTTAAATGGACCTACAACATTGCACTGTGAAATATGCAGAAAGCAGTTTGATAATGCTAAAAAGTATTATGGACATTTGAGAGTACATTCTAAAGATAATCTTTGGATGTGCGATAAATGTCCAAACCAGAAGTTTTCTACAAAGCAGCAGTTAATGAAACACTCTTTGACCCACAAGCCTTTGGAGTTAATTTGGAAGTGTCCACATTGTGCCATGGCCTTTGAAGCTTTATATAAACTGCAGCAACATTGGTTCCATAAACATTTAGGCTATAGGCCCTATAAATGTGACGAGTGCGAGAAAGCCTTCTACAAACCTTCAGATCTAAAGAAACACAAAGATCAACATAGTGATGTTAAAAAATATGCATGCAGTGTCTGTGACTGGCGTTTCAAAGACAAGTCAAACATGCGAAGGCACATGCTAATTCACAACAATGAGAAGCCTTTCTGCTGTCCTGGCTGCAGGAACCGATTCAAACAGTTGGCGTCAATGAAGCGCCACGCCCAAAAGTGTCCCCTTAACAAGTTCCAGAGTGAGCCCGCAGATAAAACCATCAGGAGACACCACTGTCGTGTCTGCGGTGTAAGCTTTCAGTACAAAAGTGCTTTGTTAGAACATTGTGTTAGACAACATAGCAACAATGCCGCGGAACCCTACAAGGAAGATAAATTCCAAAATAGTGATGCGAATGGTATTGTCGATAACATCGTAGACGATATACTGTCTGCAGAAGACGACTACATGACCATGTCCACACAAAACGATATATTACACACACAAAATGTTTATAACCAAAACGAAACATTACACACACGAAATGTGTACAATCAAAACGAAATAGACAACACCGCTGACAATCTAATGCACATCGAGCTGCTCAAAGAAATGAACACATTTCAAATATTAGACGAAGAACTATTCTATAACGACATAGACTTCGAGAGTATACCACCTAGCCACATTTTTAACACTAACACAAACGATATGGATTACACACAAAACAAAAATGGAGAAGTCCTCTTTGATTTCAATGACGGTAAAAGTATTGACCAAGATATTATGAACGCGTTATGTCATGTAAAAGCAGAACTACCAGATGAACTACTTCATCCAGACGTACTTATACAGAAGAATAGCGAAGTAGAAAATCCTGTGTCAGTTAATGAATGCGCTACGATATTTGAAAGTGATGTTGACTTAGAAGCAAGTACTAACTTAGCAGCTAATTTGAATCAGTTGATCGGAGAAAATCGTGTGCAATACATATCTACGGAACATGATGATACATTTATAATTAGTTTGAATAGTGAAATAGATGCTGAAAAGTTAACGGATATGTTAAATATAGGTGTAGAGCTAGTAAATAATAAAAAAGATGAAAATGTTTCTCCTGAAGTTAATGATGAAAGTAGAACAGCTGGATTAAGTGAGCCTGTTGTATTGAAGATTGAAAAGCCAGAAGGACCGCTTATAGTTAAAATTGATAAATCAGAAAGCGTTGTTCAGCCAAAAGTGACAAATCTAGATGAAAAGGAAGTAAAGGTGAAAGTGAAGAACAAATTAAATATATTTGTTTGTAGAACATGTAATAAAGTCTTCAATAAGAAATATAACTATGACTCCCACAGAGCGTTGCACGAGCCATCACTCCGTGCACACGTGTGCGGCGTCTGCGGAGAACGCTTCGGCTACCGCTCTACCCTTAACAAGCACCGGCGTCTGCACACACCGTCCGTTTTGCCGGCGCACCAGTGTCACCTCTGTCACAACACCTACTCTGCCCTCTGGCTGCTGAAGACTCATCTGTCCCGCGACCACGAAGGTCTGACTCCGCACGTGTGTGAGCACGCCGGCTGTGGGAAGCAATTTTACAAGAAGAGCGACCTCGTCGTACATAAAAGGTATCACACGGGCGAGCGTCCATATTCATGCGAGCACTGCCAGCGGTCTTTCCTGCATGTGTCGCACCTGCACCGACACAGCAGAACCGCCTCCTGCACAAAACTGTGA
- Protein Sequence
- MDSNLPFYSLPFVDSDATDIEFNKLKPQESVYDVLNPALPSSSALLGSDDVLAQFLSGDEPLEEPDLNGPTTLHCEICRKQFDNAKKYYGHLRVHSKDNLWMCDKCPNQKFSTKQQLMKHSLTHKPLELIWKCPHCAMAFEALYKLQQHWFHKHLGYRPYKCDECEKAFYKPSDLKKHKDQHSDVKKYACSVCDWRFKDKSNMRRHMLIHNNEKPFCCPGCRNRFKQLASMKRHAQKCPLNKFQSEPADKTIRRHHCRVCGVSFQYKSALLEHCVRQHSNNAAEPYKEDKFQNSDANGIVDNIVDDILSAEDDYMTMSTQNDILHTQNVYNQNETLHTRNVYNQNEIDNTADNLMHIELLKEMNTFQILDEELFYNDIDFESIPPSHIFNTNTNDMDYTQNKNGEVLFDFNDGKSIDQDIMNALCHVKAELPDELLHPDVLIQKNSEVENPVSVNECATIFESDVDLEASTNLAANLNQLIGENRVQYISTEHDDTFIISLNSEIDAEKLTDMLNIGVELVNNKKDENVSPEVNDESRTAGLSEPVVLKIEKPEGPLIVKIDKSESVVQPKVTNLDEKEVKVKVKNKLNIFVCRTCNKVFNKKYNYDSHRALHEPSLRAHVCGVCGERFGYRSTLNKHRRLHTPSVLPAHQCHLCHNTYSALWLLKTHLSRDHEGLTPHVCEHAGCGKQFYKKSDLVVHKRYHTGERPYSCEHCQRSFLHVSHLHRHSRTASCTKL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01198119;
- 90% Identity
- -
- 80% Identity
- -