Basic Information

Insect: Tyria jacobaeae
Gene Symbol: znf423
Assembly: GCA_947561695.1
Location: OX387219.1:16744954-16754622[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 3.9 3.1e+02 2.6 0.8 1 23 84 107 84 107 0.94

2 19 3.9 3.1e+02 2.6 0.1 3 23 112 132 110 132 0.94

3 19 0.12 9.3 7.4 0.1 3 23 388 409 386 409 0.95

4 19 1.3 1e+02 4.2 0.0 1 20 417 436 417 438 0.93

5 19 0.068 5.5 8.2 2.1 3 23 449 469 448 469 0.96

6 19 7.8 6.3e+02 1.7 1.1 1 23 485 508 485 508 0.83

7 19 0.00052 0.042 14.8 0.9 1 23 517 540 517 540 0.95

8 19 0.35 28 5.9 1.0 2 23 552 574 551 574 0.93

9 19 0.0016 0.13 13.3 0.0 2 23 617 639 616 639 0.93

10 19 8.9 7.2e+02 1.5 3.9 1 23 644 667 644 667 0.95

11 19 3.3e-05 0.0027 18.6 1.9 1 23 673 695 673 695 0.97

12 19 1.2e-05 0.00093 20.0 1.9 1 23 702 724 702 724 0.98

13 19 8.6e-05 0.0069 17.3 2.3 1 23 729 751 729 751 0.96

14 19 0.00025 0.02 15.9 2.1 1 23 757 779 757 779 0.98

15 19 4.8e-07 3.8e-05 24.4 1.9 1 23 785 807 785 807 0.98

16 19 0.00038 0.03 15.3 3.5 2 23 814 835 814 835 0.98

17 19 0.00071 0.057 14.4 0.3 2 23 843 865 842 865 0.97

18 19 2.8e-05 0.0023 18.8 0.3 1 23 870 892 870 892 0.96

19 19 0.015 1.2 10.2 4.7 1 23 898 921 898 921 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	3.9	3.1e+02	2.6	0.8	1	23	84	107	84	107	0.94
2	19	3.9	3.1e+02	2.6	0.1	3	23	112	132	110	132	0.94
3	19	0.12	9.3	7.4	0.1	3	23	388	409	386	409	0.95
4	19	1.3	1e+02	4.2	0.0	1	20	417	436	417	438	0.93
5	19	0.068	5.5	8.2	2.1	3	23	449	469	448	469	0.96
6	19	7.8	6.3e+02	1.7	1.1	1	23	485	508	485	508	0.83
7	19	0.00052	0.042	14.8	0.9	1	23	517	540	517	540	0.95
8	19	0.35	28	5.9	1.0	2	23	552	574	551	574	0.93
9	19	0.0016	0.13	13.3	0.0	2	23	617	639	616	639	0.93
10	19	8.9	7.2e+02	1.5	3.9	1	23	644	667	644	667	0.95
11	19	3.3e-05	0.0027	18.6	1.9	1	23	673	695	673	695	0.97
12	19	1.2e-05	0.00093	20.0	1.9	1	23	702	724	702	724	0.98
13	19	8.6e-05	0.0069	17.3	2.3	1	23	729	751	729	751	0.96
14	19	0.00025	0.02	15.9	2.1	1	23	757	779	757	779	0.98
15	19	4.8e-07	3.8e-05	24.4	1.9	1	23	785	807	785	807	0.98
16	19	0.00038	0.03	15.3	3.5	2	23	814	835	814	835	0.98
17	19	0.00071	0.057	14.4	0.3	2	23	843	865	842	865	0.97
18	19	2.8e-05	0.0023	18.8	0.3	1	23	870	892	870	892	0.96
19	19	0.015	1.2	10.2	4.7	1	23	898	921	898	921	0.98

Sequence Information

Coding Sequence: ATGACGTCTGATGAGTCCGACGATGAGCCGCTATCAGTTCTAGCAGCTACCAAGAAACTGCACCCCGAAACCTTCATCGAAAAAACTACAATAATAAATACAAAAGTTATAAAAAAGAAGAAAAAGAAATTAGTGCCGCCAAAGCGTTTACCGATTACTATAAACATCCAGAAGCCAGATCTGCCGCCAGTTATAGAGCGGCCTGCGGATGTTTGGCTTTATTTGAAGGATTTTAACCCGGCAGGCCCTTACAGTTGCTTATTATGTCCTGAATGGTTTATAAACAGGTCTAAAATAATCCTGCACTATTGCCTGAATCATAAGAAAGATTTTTGTGGTATTTGCAGGTACTTTGTGCCAGATAGGGAAAGTTGGTGGAGCCATGAGAAATTTCATACACCATGGCCATGTTCACAATGCATTGAAAACTTCCCTACTGAGCCAATTTTACGTTTGCACCTTAAAACAGTTCACAAGCTTGTGCACTGCAGACTGTGCCATTTTAGAGTTTCTGATGGTGAATTATACAACTCACATTTATTTCAAAAACATAATGTGTCTAATGTAGCCAATAAAGATGAAGAAATTCTATGGGATTTGGATTATGAAGGCTGTCCAACCTTTTCATGTGTTCTATGTTCAAAGACTGATAATGTTGTAAGAACATTCTTCAATCACTATATGGGCTATCACCACTTCACTTTAAAGTGCTTTACAGCCCTGCTGGCTGGTAAAGATTTACCATTTGTGGTGAATGGAGCAGATGTTAGAAATGAATTCATAGAAGAACAACTGAAACATCATTCTAGATATGGTTATGTAGATTTAGAGATTAAAGTTGGCAATAGCTTAGGATCTGATTCTAACACAAGTGATGCAAAAGAGTTGCTCAAAGTTCTATTGCCAGAGATCAAACAAGAGAATGTAAGTGGTGATGAAGCAAAGGGCAACAAGGAAAAGGACTCGAAGCTGCTTGAGTTTGTTAAAAGTTATGAGGGTGATGAAGACTATGATGTAACACTAACTGAATTAGTTGTTTTAGAAAAGTGTTTCTTTGATTACATTTCTCAAGTATTATCAGATATCAAATCAAATATAGTTAATGAGAGTTCTAACATTGATTATGAGAAATCTACAGCTGAACTAAGTATGGATATAGCGTGCCCTTTGTGTAATGTTGAGTATAACAATGTACAAACATTTGTTGCACATATGACAAAAATGCATTCTGTTAAGTATAAGGCAATGTACTCATGTAGGCTATGTGCAGCAATATTTGACAGCCAGAATGAACTTGACAATCATGTTGCCAGAGAGTTGGGGGATTTTAAAGACCTCTGGCTTTGTCAGTTCTGTGACAAGGAGTTTGATAATAGACAGAAAACAAGAAAACATTTATCAGAGCATTGGGACTTATTAGAATATGATAATTGTTTTAGTCCACATTTGGGCTTCAAGTGTGCATATTGCCCAACTTTGTTCTGGCATGAAAGGGACAGGGAAACTCATCAAGTTCGAGTTCATTTTACGAGACACAAAGATAACTACTATAAATGTGAAGTATGCAGCGAGGTGTTCAGTGATAAGATTTGGTTCATCCACCACTACTTATTAAGTCACTCTACTGCAGATAAAGTCCCTCTCTACCTCATTAAGTGTTGTTTATGTGGCTTGGTGTTGTCTAACGTCGATGATATGAGGTCCCACTTTAAATTGCAACATCCAGAAGCTAAGAAATTGTATTGCTCCCTAGATACTTGCAAATTTAAACCATTGAGTCACAGGAAGAGCTTCAAACTTCATGTGAGGTCTATCCACAATCCTCATCACCGCGTCGAACGCAACTTAGAATGTACCGTGTGTGGCCGGGAGTTTACTAGCTCGAGGGCCGCAAGCGCGCATATGGCCCAAGCGCATGGCCCAGGCAAATTTAAGTGCAAACTGTGCGAGGAAGTTCTGCACACTATGGATGAGAGAAAACTCCATTATCTAATGTGTCACCCTGGACAGCATCCATTTGAGTGTACAGAGTGTGGCAAGTCGTTTCAGTACAAATCTTCTCTATACATGCACAAACAAGAACACATGCCTAATAAACAAAACTATACGTGCACTTACTGTGGAAAGACTTTCATGAAACGCGACTCGTTCCGTGAACATGTCCAAATTCACGAGGGGCCGCGTCACGCTTGCTCGTACTGCCCGATGCGGTTCGTGCAACGTTCCAACATGTTACGTCACGAGCGACGTCATACGGGCGAGCGGCCGTACGCTTGTCCCCACTGTCCACGTAGCTTTGCTGATAAGGGAGCGTGTAATTCACATACCAGAACCCATTCAAGAGACACGTCGTATGCGTGTATGTATTGTGGGAAGACTTTTGTTCAAAAGTCTAAGCTGACATATCATATAAGGAAGCACACCGGCGAGAATTTAGAAACATGTACAGTCTGTTCGAAGTTGTTTACGAGTGCCTGTTCGTTACGTGAGCATATGAAGACACACACCGTTAAAAAGAACACTATCAAATGCCCCTTGTGTGACCGCATGTATGCGGACGACCGCTACATGCTCCGCCATTTACGAACGTCGCACACGCGCGCAACACACGCATGCCCGATCTGCGGCAAGATGCTCACCAGCCCCGCCGGACTCAGGCATCACGTCATCACGCACACTGACCTCAAGACGTTCAAATGCAAATTATGTCCCAAGGCGTGCTCCGTGAAAAGAACGATGGTGAAACACTTCCGTAGACGACACGGTTTTAAAGGCAATGAACCTAATATTAAAGATTTTTACACTCGATTGGAACCAAGGGAATGCAATCTAGGCCTCGAGGAGGATGTCATGACCAGCATATTTGGACCTCCGAAGAAACCTGCGAATGAACTACTGATTGGAGACTATGTAACGCTGGCCAATTTAGAAAAACATAAGCAAGATTTGCAAGAGAAACAAACAGAGTCCAACCTAGAAATAGATGACGATGAGGAAGATGATGAAATAAATGATAACTCTAAATCTGATTCAGAGGACTCAAGAGAGGGTGAGAAAGACAACAGTGATTCGGAGCGTGATATTAAGCCTCATATTGTCAAAATTGAAACTAAAGATTACAGTGAACATGATGGAGACAATGATTTGGAACCCACTGACTTTGTTAGTGTCAAAATTGAGCCTATGGATGATGAAGATTATAATGACAATTGA
Protein Sequence: MTSDESDDEPLSVLAATKKLHPETFIEKTTIINTKVIKKKKKKLVPPKRLPITINIQKPDLPPVIERPADVWLYLKDFNPAGPYSCLLCPEWFINRSKIILHYCLNHKKDFCGICRYFVPDRESWWSHEKFHTPWPCSQCIENFPTEPILRLHLKTVHKLVHCRLCHFRVSDGELYNSHLFQKHNVSNVANKDEEILWDLDYEGCPTFSCVLCSKTDNVVRTFFNHYMGYHHFTLKCFTALLAGKDLPFVVNGADVRNEFIEEQLKHHSRYGYVDLEIKVGNSLGSDSNTSDAKELLKVLLPEIKQENVSGDEAKGNKEKDSKLLEFVKSYEGDEDYDVTLTELVVLEKCFFDYISQVLSDIKSNIVNESSNIDYEKSTAELSMDIACPLCNVEYNNVQTFVAHMTKMHSVKYKAMYSCRLCAAIFDSQNELDNHVARELGDFKDLWLCQFCDKEFDNRQKTRKHLSEHWDLLEYDNCFSPHLGFKCAYCPTLFWHERDRETHQVRVHFTRHKDNYYKCEVCSEVFSDKIWFIHHYLLSHSTADKVPLYLIKCCLCGLVLSNVDDMRSHFKLQHPEAKKLYCSLDTCKFKPLSHRKSFKLHVRSIHNPHHRVERNLECTVCGREFTSSRAASAHMAQAHGPGKFKCKLCEEVLHTMDERKLHYLMCHPGQHPFECTECGKSFQYKSSLYMHKQEHMPNKQNYTCTYCGKTFMKRDSFREHVQIHEGPRHACSYCPMRFVQRSNMLRHERRHTGERPYACPHCPRSFADKGACNSHTRTHSRDTSYACMYCGKTFVQKSKLTYHIRKHTGENLETCTVCSKLFTSACSLREHMKTHTVKKNTIKCPLCDRMYADDRYMLRHLRTSHTRATHACPICGKMLTSPAGLRHHVITHTDLKTFKCKLCPKACSVKRTMVKHFRRRHGFKGNEPNIKDFYTRLEPRECNLGLEEDVMTSIFGPPKKPANELLIGDYVTLANLEKHKQDLQEKQTESNLEIDDDEEDDEINDNSKSDSEDSREGEKDNSDSERDIKPHIVKIETKDYSEHDGDNDLEPTDFVSVKIEPMDDEDYNDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00441828;
90% Identity: iTF_00707270;
80% Identity: -