Tjac017533.1
Basic Information
- Insect
- Tyria jacobaeae
- Gene Symbol
- ZNF296
- Assembly
- GCA_947561695.1
- Location
- OX387237.1:8299966-8316748[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.19 15 6.7 0.2 3 23 115 135 113 135 0.96 2 14 0.0017 0.14 13.2 2.8 1 23 250 272 250 272 0.99 3 14 1.8e-05 0.0014 19.4 0.5 1 23 278 301 278 301 0.97 4 14 0.0018 0.14 13.2 2.5 1 23 306 329 306 329 0.94 5 14 4.8e-05 0.0039 18.1 0.5 2 23 496 517 495 517 0.98 6 14 2.2e-05 0.0017 19.2 1.4 1 23 523 545 523 545 0.98 7 14 4 3.2e+02 2.6 0.0 2 23 632 653 631 653 0.91 8 14 0.0013 0.1 13.6 2.0 1 23 659 681 659 681 0.95 9 14 0.00038 0.031 15.2 0.9 1 23 687 709 687 709 0.98 10 14 0.0048 0.38 11.8 3.6 1 23 717 739 717 739 0.98 11 14 0.00056 0.045 14.7 3.0 3 23 787 807 786 807 0.97 12 14 0.0034 0.27 12.3 3.2 1 23 824 846 824 846 0.96 13 14 1.5e-06 0.00012 22.8 0.7 1 23 852 874 852 874 0.98 14 14 1.6e-07 1.3e-05 25.9 3.1 1 23 880 903 880 903 0.98
Sequence Information
- Coding Sequence
- ATGAACATCGGCATGGACTTAGATCCACTCAGCACATATGAATACCCTACATACAATAGTTACCATTCTTTAAACAATACCCAACCATTGGACATACCACCTTACCAACATGTTAAACAAGAAGAAAGTTATTATAATCAACAAATACAAAACAATACGGGTTATATCAACAATGCACCACAAAATGTACCTCAAAACCTACTACCACAAATAAATAAACTAGAAATAACGAATCAAGAGAATGAAATAGAAACAGATGTAAAAAAGAAGAAACTAGACAAAAAGAATGGAAAGAATTTCTGTTCACAGAAGATTAACGATGCAACATATCCATTTTACGGTTGCTCAGTCTGCAATATCAGTTACACAGCATTACATGAACTTGATCAACATGTCACTGTACACAAAAATAGAATGACGAGTTACAGGTTAAGGTTAAGAAATCAGTATAAAAAGAAACAGATAAAGAAAGAGAAGAAGAAATTGAAGAAGTTAAAGAAGATTAAGCAGGAGAATGAAACGGAGATTGAAATCAAGCCTGAAGATGGTTATATTGGCAATGAAAAGACTTCAGATTATGTTAATAATGAAGAAGCAGATAGAGATAAAAAAGATGATGTAAAAGAGTCTGTTAGTAGAGATTTAAGTAGAGAAGATGATAGTAAAACTAGTGAGAGTAAGACAGAGAGTAGTAAGAGTAACGAAAAGGATGCTGACGATGCAGAATTGAATAATTTAGAGAAAATATACAAATGTTTTGCTTGTCAGAAACAATTTACTTTAAGTTATTATTTGAAGTTACATGTAAGATCTCATACAGATGAGAAACCTTACACATGCAATGTGTGCGGTCAGTCGTTTATAACAGCGAGCAAACTCGGGAGGCACAATAAAAGAATACATCTCGCCGCGAGGTTTCAGTGTCGAATATGTTTTAAGATATTTTCTAGGTTTGAACTACTAACAAATCATTTTGATAAAAGTCATCCCGAAGACAAATTAGAAGGTGAACCGTATGATTACAACGCTATTCTGCCATACCTCAAAGAGCTAGAAGAACAACTCAAAGAACAGGCTGAAGCTAAAGAACAGAAGAAAGATGACACTTGGTTTGAGACTACATTTGGTACAGAAGGTGACGAGGTCAAGAAAGAGAACCAAAACCAAGAAGAAGAAAAGCTAGTACCCAAGATAGACATAATTGTAGAAGACTTGAAAGTAGACAGTTTTGATGATGTTAAAGTCAAGCAGGAGGTAGAAGATGATGAGGGACACAATAAACAGATTGAGATTGAGACTCCTGGAGAAGACTTCCGAAATGATGATGATGATGTTGATGATGATTTTAAAGACCAGGATTTTAAAGATGACAGCCCTTCGGATGAAGACTATTTCCCCTCAAACACATGGGCGTCAACCCCAAAATGCGACCCATCCCCACCCCCATCGCCGAAACGCAGGAAGACATCCACATTTAAGACGAAGACGTGTGAGATATGCAACAAGGAGATCAGCTCAGCATCATACATGAGGGTACACATGCGGACCCACACTGGGGAGAAACCGTTCAAGTGTTACACGTGTGGCCGCGGCTTTATAACTAGCAGCAAGATGAATAGACACGTGCTGACACATGGGACTGATGCTAAAGAAGAAGAAATCAAACAAGAAGATACAGAAGTGAAAGAAGAAGAAGAAGCACCAACAGAAGATATCACAAATTCAACAAAGAAGAAGAGGAAGAAACGAAAAGCATCATCGAAGGGAGAAGAGAAGGTGAGGAAGAAACATCAGAAGCGGCCGCACTCCTGTGAATATTGCAACCAGAAGTTCCTTCACCTGAAGATGCTGGAGGTGCACAAGAAGTGTCACTCGGGCGAGGCGCTGGTGCTGAAGTGCCAGTTCTGTCTGCAGGAGGCTCCTGACGCTTCCGCGCTCCGGGAGCACGAGGCCGAGCACTCCGGCGCCAAGCCCTACCTCTGCACCATCTGCGGGAAGACTTACAAGAAGAGAGAGACCATGGTGTACCACCGCAAGCAGCACCAGCCCGAGAGAGAGTTCGTGTGCGACGTGTGCTCGAAGCGGTTCAGCGCGGCGTGCAAGCTCGCCAAGCACCTCGCCACGCACCGCGCCGGCTACGTGCTGCGCTACGAGTGTCCCGTCTGCGCGCACATGTTCAACACGCAGTACCACGTGCACATGCACCTCGCCACGCACCAGAAGGAGGGGCTGATTTTGGAATCGAACCGCAACGAAGTGCTAGCGATGGTGCTACAGAACGCGCTGAAGATCCCCAAACAACCCGACGCGGCCTCCAACTTAACAGACATCACACCCTCAGACGAAAGATACAGAATCTGCAAAATCTGCGGCGAAACCTTCCACCATTTCTACTACTTAGAAGAACACCTCAAGAGCCACGGATCCAAGATAGCCATAGGCGACACCAACAAACAAGAAGAGAAGAAATACATCTGTGAGATATGTAACAAGGGATTCAAACTTCATTATTATTTAAAACTACACAGTTTTACACACTCCAAGGAGAAACCTTTCATATGTCAACAGTGTGGCAAAGGTTTTATAACTAAAGGTAAACTCAAGAGGCACTTGGAGACTCACTCCGGGCTCAAGAAGTATCAATGTCACATTTGTTATAAATTCTTTACGCGACCGAGTTATTTGAGGATACACATTCGGACAATCCACGGAACTCAAGATTATAATTATCGGTTTGATAAATCTCTATCGTTATCGGCCATCTCGGCGTTAGCTCACATGTCTGATAGACAGAACGTGTAG
- Protein Sequence
- MNIGMDLDPLSTYEYPTYNSYHSLNNTQPLDIPPYQHVKQEESYYNQQIQNNTGYINNAPQNVPQNLLPQINKLEITNQENEIETDVKKKKLDKKNGKNFCSQKINDATYPFYGCSVCNISYTALHELDQHVTVHKNRMTSYRLRLRNQYKKKQIKKEKKKLKKLKKIKQENETEIEIKPEDGYIGNEKTSDYVNNEEADRDKKDDVKESVSRDLSREDDSKTSESKTESSKSNEKDADDAELNNLEKIYKCFACQKQFTLSYYLKLHVRSHTDEKPYTCNVCGQSFITASKLGRHNKRIHLAARFQCRICFKIFSRFELLTNHFDKSHPEDKLEGEPYDYNAILPYLKELEEQLKEQAEAKEQKKDDTWFETTFGTEGDEVKKENQNQEEEKLVPKIDIIVEDLKVDSFDDVKVKQEVEDDEGHNKQIEIETPGEDFRNDDDDVDDDFKDQDFKDDSPSDEDYFPSNTWASTPKCDPSPPPSPKRRKTSTFKTKTCEICNKEISSASYMRVHMRTHTGEKPFKCYTCGRGFITSSKMNRHVLTHGTDAKEEEIKQEDTEVKEEEEAPTEDITNSTKKKRKKRKASSKGEEKVRKKHQKRPHSCEYCNQKFLHLKMLEVHKKCHSGEALVLKCQFCLQEAPDASALREHEAEHSGAKPYLCTICGKTYKKRETMVYHRKQHQPEREFVCDVCSKRFSAACKLAKHLATHRAGYVLRYECPVCAHMFNTQYHVHMHLATHQKEGLILESNRNEVLAMVLQNALKIPKQPDAASNLTDITPSDERYRICKICGETFHHFYYLEEHLKSHGSKIAIGDTNKQEEKKYICEICNKGFKLHYYLKLHSFTHSKEKPFICQQCGKGFITKGKLKRHLETHSGLKKYQCHICYKFFTRPSYLRIHIRTIHGTQDYNYRFDKSLSLSAISALAHMSDRQNV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00157427;
- 90% Identity
- -
- 80% Identity
- -