Basic Information

Insect: Trypoxylus dichotomus
Gene Symbol: zfh1
Assembly: GCA_014905495.1
Location: BNES01000008.1:776974-796345[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.011 0.94 10.5 1.5 2 23 37 59 36 59 0.90

2 9 0.00027 0.024 15.5 0.3 1 23 93 115 93 115 0.95

3 9 1.4e-05 0.0012 19.6 0.6 2 23 122 143 121 143 0.97

4 9 1.4e-06 0.00013 22.7 5.9 1 23 152 174 152 174 0.99

5 9 6.1e-05 0.0054 17.6 1.0 1 21 180 200 180 201 0.95

6 9 0.034 3 8.9 4.2 1 20 434 453 434 455 0.93

7 9 5.3e-06 0.00047 20.9 2.0 1 23 808 830 808 830 0.94

8 9 0.00015 0.013 16.4 9.4 1 23 836 858 836 858 0.98

9 9 0.0021 0.18 12.7 4.4 1 21 864 884 864 885 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.011	0.94	10.5	1.5	2	23	37	59	36	59	0.90
2	9	0.00027	0.024	15.5	0.3	1	23	93	115	93	115	0.95
3	9	1.4e-05	0.0012	19.6	0.6	2	23	122	143	121	143	0.97
4	9	1.4e-06	0.00013	22.7	5.9	1	23	152	174	152	174	0.99
5	9	6.1e-05	0.0054	17.6	1.0	1	21	180	200	180	201	0.95
6	9	0.034	3	8.9	4.2	1	20	434	453	434	455	0.93
7	9	5.3e-06	0.00047	20.9	2.0	1	23	808	830	808	830	0.94
8	9	0.00015	0.013	16.4	9.4	1	23	836	858	836	858	0.98
9	9	0.0021	0.18	12.7	4.4	1	21	864	884	864	885	0.96

Sequence Information

Coding Sequence: ATGAACTACAGATTATTGGAACAAAATACGCAAAttccTTCGATAGTGAACGGTTTAGGAAGCGGTAAAGAAGGCGACGATCATAGCAGTTCACAGGATTACTTCATAAAATGCCCGCAATGTCAAAAAGGCTATCAGACGTTCCAATCGCTCAAAGAACATATGGGCGCCTGTCATCCGGACTTGGGCGCAACGCCAGAAAACAGCGCGGTATTGCCCACGCCAGCAGGTGCCCCAATTTCCCCAACACCCAGCGTTGTAGGCACGGGAGGCCCCTTCGCTTGTTCCCAATGCGCCACCTCCTTTCCTACTAAAGACCAATTGGAAAAACACGAACTTTTGCATTCACCGAACGCGCAAGTGtcATGTAAGGTATGCAACAAAACCTTTGCCAATGTCTACCGCCTGCAAAGACATATGATCAGTCACGATGAAAGCGCTGTATTACGAAAATTCAAATGCACAGAATGTGATAAAGCTTTTAAATTCAAGCATCACTTAAAGGAACATATTAGAATACACAGCGGCGAAAAGCCATTCGAGTGCGGCAACTGTGGTAAAAGATTCTCCCATTCCGGCTCATATTCTAGTCATATGACATCGAAAAAGTGCTTAGTAATGAACTTAAAATTAGGAAGAACGAGAGCACCAACTACTAGCTCGCTTCTCGACAAGAGCTCGTCTCAAGCTAGAGGTCCAAAACGACCACCATCGAATCCTCTCAACAACAATCTCGCGACTAGCCCGAATCAAAACAGTTACTTTCCTATATTACCGAAATACACCGAAGCAGCAGCAGCTGCGCTCTTTCAAACTTCATTAGCGTCGAATCCGACCATGCACCCATTTTATATAACCCCACCTGGAATGCTAAATGCTGCAGGACACCCCATTACACCGTACTCCATGCCCACACTGGGACAATTGTTCGAGCAACTTCAAGCATCACCTCACAGACCACCTTTGCTAGAAAACCCCGAAACCAGTACTGAATGTATCAAAAAAGAACAAAGTTGTGAAGAACTAAACCCACAATCACCGGAGAGAAACAATCTGAATAAATCAAACTCCTCGAGTTGCGGAGATTTGGTAATGGATGAAGATCAACAGAAGGAGGAGACAGACGAACAACCTGAAGTACCTTCGAACGGTGGCGATTTAGAGGCTGTTAAACGGATTTTGGAAACAGTTAATGCTTCTGTCACCAAACAATTACTCCAAGCAAATATGCAGAAATTTTCCTCAGATACTAGCGATTGTAATAGCGTAGTCTCTGCTCATTCACCAAATAGGAATGAATTCGTTTGTAATAACTGCAAAAAGATCTGTAATTCTCAAAGCCATCTAGATGAACACGAATGTGAAAATGATAAAAGCGAAGGTCTCGCCGCTAAACTAGAAGACGCATTAACAACAAAATCAGAAAGTGATGTTCCAACCGGAAGTGTTAGCGGCACAGACGAGGACATGGAGTATGATAAGAATCCAGAGAAAAACGAAGATTATGAAATAGACAGTGAGAACGTTACAACGACGGATCAATTTTCAGATGATGGAAGGAAGGTTAGAGTCCGTTCACTAATATCCGACGAACAATTGAAAGTTCTTAAAGATAATTATGCTATAAATCCAAGACCGAAACGTGAAGATCTCGTGAGAATAGCAGAGAAAATCGGATTTCCTGTTAGGGTGGTTCAAGTTTGGTTCCAGAATACCCGTGCAAGAGATAGACGTGAAGGAAGATTGATCCAAATACCGTACAGCACACCGTCAATTCCGATTAGGTTTCCACAAATACCTTCAAATCCTCAATACCTCATTCACAAGGCTTATCCGTCGCCTCCTCAATATATATCCGAACAACCCCTAGATTTATCGACGAAAAAGGAACCACCGTCACACGACTCCTCACCTTCCAGCTCCCCGCGTCGACCTACATCAGTACAACATTCTGATTCAGGTGATGACGCCGTTAATTTAAGCCATAAATCGTCGCGAAGTCCAACGCCGTTCCAACAGATGCAGTACCAAAGCCATTATCAGGGTTCCAACTGCTCGTCTGAACCGAGACGTACACCATCGCCAATTGATTTTAACAATGGAAGTCGATTAGCTCAAATACTAGCTCAGCCTACGCACAAATTAGCGCAATTGCCTGGTATGGGGTTGGTTCCCATGGAAAGATTGATGCAGCTTGGTAACGCCGATTTACCCAGCTTGGGTCAATTAATTAGCAGTAGAATAACCAACCTAAGTCCAAGTTCTGATAAGAGGACGTGGTCAGAGAATGGGGATGTCCAGGAGGGCATACAAGACGACGAAGCTAGTGGTGGGAGTAAACGAAGTAAAGTGTCTCAACTTGTGATGAAAAGCTTAGGTAGTCCGATGTTGGGAAACCAAGAACAAGATGTAGAAGGCCAATTTAGCTGCGACCAATGTGATAAATCTTTTTCCAAGCAGAGTTCTTTAGCTCGCCATAAATACGAACACTCAGGTCAGCGTCCACACAAATGTGACGAGTGCCCTAAAGCATTTAAACATAAACATCACCTCACAGAACATAAACGTCTTCACAGTGGTGAAAAACCATTTCAATGTACGAAATGCCTGAAACGCTTTTCACACTCCGGTTCCTACAGTCAGCATATGAACCACCGTTATTCTTACTGCAAGCCCTACAGAGAATAA
Protein Sequence: MNYRLLEQNTQIPSIVNGLGSGKEGDDHSSSQDYFIKCPQCQKGYQTFQSLKEHMGACHPDLGATPENSAVLPTPAGAPISPTPSVVGTGGPFACSQCATSFPTKDQLEKHELLHSPNAQVSCKVCNKTFANVYRLQRHMISHDESAVLRKFKCTECDKAFKFKHHLKEHIRIHSGEKPFECGNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRTRAPTTSSLLDKSSSQARGPKRPPSNPLNNNLATSPNQNSYFPILPKYTEAAAAALFQTSLASNPTMHPFYITPPGMLNAAGHPITPYSMPTLGQLFEQLQASPHRPPLLENPETSTECIKKEQSCEELNPQSPERNNLNKSNSSSCGDLVMDEDQQKEETDEQPEVPSNGGDLEAVKRILETVNASVTKQLLQANMQKFSSDTSDCNSVVSAHSPNRNEFVCNNCKKICNSQSHLDEHECENDKSEGLAAKLEDALTTKSESDVPTGSVSGTDEDMEYDKNPEKNEDYEIDSENVTTTDQFSDDGRKVRVRSLISDEQLKVLKDNYAINPRPKREDLVRIAEKIGFPVRVVQVWFQNTRARDRREGRLIQIPYSTPSIPIRFPQIPSNPQYLIHKAYPSPPQYISEQPLDLSTKKEPPSHDSSPSSSPRRPTSVQHSDSGDDAVNLSHKSSRSPTPFQQMQYQSHYQGSNCSSEPRRTPSPIDFNNGSRLAQILAQPTHKLAQLPGMGLVPMERLMQLGNADLPSLGQLISSRITNLSPSSDKRTWSENGDVQEGIQDDEASGGSKRSKVSQLVMKSLGSPMLGNQEQDVEGQFSCDQCDKSFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHSGEKPFQCTKCLKRFSHSGSYSQHMNHRYSYCKPYRE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00433927;
90% Identity: iTF_01120765;
80% Identity: iTF_01498769;