Tdic010377.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Trypoxylus dichotomus
Gene Symbol
zfh1
Assembly
GCA_014905495.1
Location
BNES01000034.1:574885-582502[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00018 0.016 16.1 1.7 1 23 163 185 163 185 0.97
2 16 0.00026 0.023 15.6 7.4 1 23 188 210 188 210 0.98
3 16 0.00012 0.011 16.6 3.8 1 23 216 238 216 238 0.97
4 16 0.00045 0.04 14.8 0.5 3 20 246 263 244 265 0.94
5 16 7.4e-06 0.00066 20.4 0.2 1 23 272 294 272 294 0.98
6 16 0.0067 0.6 11.1 0.3 1 23 473 495 473 495 0.95
7 16 0.00014 0.013 16.4 3.1 1 23 500 522 500 522 0.98
8 16 5.5e-06 0.00049 20.9 8.4 1 23 528 550 528 550 0.98
9 16 0.0031 0.27 12.2 0.9 1 23 556 579 556 579 0.91
10 16 0.63 56 4.9 0.1 5 23 599 617 598 617 0.94
11 16 6.6e-06 0.00059 20.6 6.1 1 23 623 645 623 645 0.98
12 16 1.5e-06 0.00014 22.6 0.5 1 23 652 674 652 674 0.96
13 16 1.1e-05 0.00099 19.9 1.3 1 23 680 702 680 702 0.98
14 16 1.2e-06 0.0001 23.0 0.5 3 23 710 730 708 730 0.96
15 16 3.6e-05 0.0032 18.3 0.3 1 23 736 758 736 758 0.99
16 16 0.047 4.2 8.5 0.2 1 23 763 786 763 786 0.96

Sequence Information

Coding Sequence
ATGGAGTCTGTACAGATAGATCTGAACAATGTGTGCAGAACTTGCAAAAATGAGTCGCCAGAAATGAAGTCGTTGTATTATAGAGACTCTGAAAGTGGCAAAGAAAACCCCCGTTTAGACGAGATGCTAATGGCATGTGCTTCCGTTCAGGTTAATAACGACGACGGGCTACCTAAATTGATATGTCGATCGTGTTTTGTGCAATTAAAGAACGCGTATTCGTTCAAGGAACAATGCGAAAAGACGGATATATTTTTAAGAGATTACGTGAAGCACTTAAAAAAGGCAAATATCAAGGAGGAAAATGCTGTGACCGATTTGgatttttcatcaaatttaataaatgaatgtGACATAACATTAGATGATGACAGTtgcaataaaaacgaaatagttGGGATCAAAGATGATCCAGAAAACAATTCTGGTGAATCTCAAGGGAAAGATACGGACTATGTACAGGTAGATGATAGTAACTTAATGATTTATGAATGTAGAACATGTTCAAAGGTCTTTTACACCTTGGAAGACCTAAGAAGCCATAAAAAGGAACATAGAAGCTTCAAATGCAAACAATGTAATAAGTCCTATACAAGATTGAATCATCTCCATAGACACGAATTATCTCATGGTAAACGGAAAATGCATGTCTGCAAGATATGCAATAGGACACTTGCCAGGTTTGAACATTTGAAGCGTCACCtaataacacatttaaaagaaaagccTTATGGTTGCCCCAATTGCAACCGTGGCTTTAATCGCTTTGGACATCTTCAAAAGCACCTTGGAACTTGCAAAGGAGAAAAGGTTTATGTGTGTGATATTTGCAATCGAGCTTTTAATCGAGAAGATAGCATGGAGGTCCATAGACGCATACATGAACATAGATTACCTGTTTTACCAACTTTAGATAATTTGGATAATATAGAAGAACATTATATGGAGATTGAGGTCGATGAAAAAGCTAATGCTTTTTCTGATCAATCCGATTGTGAAGAAGTGTATATAGCTGAGGAGACGATGGAACCAGAAGTTGAGGTTTCGGAGGAAAATGATCAAGAGAAAATAGATGAAATAGACCATATAACTAATGAGATGTATGCAAAAGAGGATTCCACAGAAATGCTGATTGAGAAAACAGAACAGGAAGAAATGTTTgtagaaaacaatgaaaatggTAGTGTAGTGGAGCAAGATGAAGTTTTAGATGCTGATAATGGAAATGATTATGAATCTGATAATGATAGTGCCCATTCCGAATATTTGCCAGCGAAACCGCCGTCACCGAAAATTAAACGTGGTAGGGGGCGACCTCGCAAGCACTCTGTCGCATACAAGCCTACCGGCAGACCTAGAGGGCGTCCTCCTCTCAAACATAAGTTCAAAAATGATTCGGCTGGAGAAACTAACAGTTTCGAATGTCCAGAGTGCAAGCAACTGTTCACcaaagttaatttatttgagaGGCACGTTGAAGAGCACGGCCTGAAGCTGTACGAGTGCGAcacatgttttaagaaatttagcaGAATAAATAGTCTTAAAAGACATAAATTATCTCATGGGCAGGTGAAGCCGTTTTCGTGTTCGTCTTGTAAAAAGTGTTTTTCAAGACGGGACCATTTGCAGAAGCATATGAGATTACATCTCAGTTCTGATTCATTTACGTGCGATGTTTGCCAGATGATATTTAGTAAAGAAGAAAGCTTgttaaagcataaaatatttaagcatAACCTTCGCGACAAAATACCGTTAGATTTTAAGATCGGAAAGAAATATAAACGCGAACAATGCCCGAAAGCTTTTCCCACCGAAAAATATCGCGAGTCACATACGAAAGATCATTACGGGGAGAATACATTCCAGTGTAGGACTTGTGAGAAGACTTTTAGATCGAAATCTCATTTAACCGAGCATATGAAGTTCCATGATGATAGTTCGAAGAAATTTTTGTGTTCTGAGTGCGGACAGAGATTTATTAGAAACGATTATTTGGTGGTTCACATGAGACGGCATCGCGGCGAGAAACCTTTTAAATGCAAGTTTTGTGGTAAAGGTTTTCCTCGTACAACAGATTTGACAGTCCATGAGAGGTACCATACTGGTGAAAAGACGCATTTATGCGTTATATGTGGAAGAGGTTTTGGAAGGGCTTATAACCTAACGGTTCACATGAGAACTCACACCGGAGAAAAACCTTATCGCTGTACATATTGCGATGCAGCCTTCGCCCAGGGTAACGATTTGAAATCGCACGTCCGCAGACACACAGGAGAAAGATTCCAGTGCGAACTATGTCCGGAAACGTTTTTAATGGGATACTTATTAACACAACACAAAAGAGTCGTGCACGGTTTAAATATCGTTAGCAATATAAGGCGATTGCAACGAGTTGCGGCATTAAATCCAGACGATCCTCCCCCGATAACAGTACCATTGCCTGCACCTGTGGTAATACTACCTACCATTAAGCTCGATCCGCTACAAATAAGCCAGGATGACATGCCTGAACTGAAGCAAGAGTAA
Protein Sequence
MESVQIDLNNVCRTCKNESPEMKSLYYRDSESGKENPRLDEMLMACASVQVNNDDGLPKLICRSCFVQLKNAYSFKEQCEKTDIFLRDYVKHLKKANIKEENAVTDLDFSSNLINECDITLDDDSCNKNEIVGIKDDPENNSGESQGKDTDYVQVDDSNLMIYECRTCSKVFYTLEDLRSHKKEHRSFKCKQCNKSYTRLNHLHRHELSHGKRKMHVCKICNRTLARFEHLKRHLITHLKEKPYGCPNCNRGFNRFGHLQKHLGTCKGEKVYVCDICNRAFNREDSMEVHRRIHEHRLPVLPTLDNLDNIEEHYMEIEVDEKANAFSDQSDCEEVYIAEETMEPEVEVSEENDQEKIDEIDHITNEMYAKEDSTEMLIEKTEQEEMFVENNENGSVVEQDEVLDADNGNDYESDNDSAHSEYLPAKPPSPKIKRGRGRPRKHSVAYKPTGRPRGRPPLKHKFKNDSAGETNSFECPECKQLFTKVNLFERHVEEHGLKLYECDTCFKKFSRINSLKRHKLSHGQVKPFSCSSCKKCFSRRDHLQKHMRLHLSSDSFTCDVCQMIFSKEESLLKHKIFKHNLRDKIPLDFKIGKKYKREQCPKAFPTEKYRESHTKDHYGENTFQCRTCEKTFRSKSHLTEHMKFHDDSSKKFLCSECGQRFIRNDYLVVHMRRHRGEKPFKCKFCGKGFPRTTDLTVHERYHTGEKTHLCVICGRGFGRAYNLTVHMRTHTGEKPYRCTYCDAAFAQGNDLKSHVRRHTGERFQCELCPETFLMGYLLTQHKRVVHGLNIVSNIRRLQRVAALNPDDPPPITVPLPAPVVILPTIKLDPLQISQDDMPELKQE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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