Basic Information

Insect: Trypoxylon attenuatum
Gene Symbol: znf423
Assembly: GCA_963989405.1
Location: OZ022493.1:6110189-6122777[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 0.00048 0.045 14.4 3.3 1 23 92 114 92 114 0.98

2 21 0.19 18 6.2 4.9 1 23 120 142 120 142 0.98

3 21 9.8e-07 9.2e-05 22.8 4.3 1 23 148 170 148 170 0.99

4 21 0.00021 0.02 15.5 0.2 1 23 176 198 176 198 0.99

5 21 0.00012 0.011 16.3 0.6 1 23 358 381 358 381 0.96

6 21 0.46 43 5.0 0.0 2 23 392 414 391 414 0.88

7 21 0.39 37 5.2 0.1 3 23 476 496 475 496 0.97

8 21 0.0057 0.53 11.0 0.4 1 23 508 530 508 530 0.96

9 21 0.013 1.3 9.8 0.3 1 23 539 562 539 562 0.92

10 21 3.5 3.3e+02 2.2 0.2 1 23 567 590 567 590 0.91

11 21 0.31 29 5.5 0.6 2 23 664 685 664 685 0.96

12 21 0.008 0.75 10.5 0.0 1 23 690 713 690 713 0.94

13 21 3.1 3e+02 2.3 0.1 2 23 777 800 776 800 0.81

14 21 4.7e-05 0.0044 17.5 1.0 2 23 816 838 815 838 0.96

15 21 1 98 3.8 0.6 1 12 847 858 847 870 0.76

16 21 0.25 23 5.8 0.3 2 23 878 899 877 899 0.96

17 21 0.0011 0.11 13.2 0.1 2 23 1064 1086 1063 1086 0.93

18 21 0.19 18 6.2 0.1 1 23 1094 1117 1094 1117 0.94

19 21 3 2.8e+02 2.4 0.2 2 23 1129 1150 1128 1150 0.93

20 21 0.45 42 5.0 0.1 2 23 1159 1181 1158 1181 0.93

21 21 0.067 6.3 7.6 1.9 1 23 1188 1211 1188 1211 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	0.00048	0.045	14.4	3.3	1	23	92	114	92	114	0.98
2	21	0.19	18	6.2	4.9	1	23	120	142	120	142	0.98
3	21	9.8e-07	9.2e-05	22.8	4.3	1	23	148	170	148	170	0.99
4	21	0.00021	0.02	15.5	0.2	1	23	176	198	176	198	0.99
5	21	0.00012	0.011	16.3	0.6	1	23	358	381	358	381	0.96
6	21	0.46	43	5.0	0.0	2	23	392	414	391	414	0.88
7	21	0.39	37	5.2	0.1	3	23	476	496	475	496	0.97
8	21	0.0057	0.53	11.0	0.4	1	23	508	530	508	530	0.96
9	21	0.013	1.3	9.8	0.3	1	23	539	562	539	562	0.92
10	21	3.5	3.3e+02	2.2	0.2	1	23	567	590	567	590	0.91
11	21	0.31	29	5.5	0.6	2	23	664	685	664	685	0.96
12	21	0.008	0.75	10.5	0.0	1	23	690	713	690	713	0.94
13	21	3.1	3e+02	2.3	0.1	2	23	777	800	776	800	0.81
14	21	4.7e-05	0.0044	17.5	1.0	2	23	816	838	815	838	0.96
15	21	1	98	3.8	0.6	1	12	847	858	847	870	0.76
16	21	0.25	23	5.8	0.3	2	23	878	899	877	899	0.96
17	21	0.0011	0.11	13.2	0.1	2	23	1064	1086	1063	1086	0.93
18	21	0.19	18	6.2	0.1	1	23	1094	1117	1094	1117	0.94
19	21	3	2.8e+02	2.4	0.2	2	23	1129	1150	1128	1150	0.93
20	21	0.45	42	5.0	0.1	2	23	1159	1181	1158	1181	0.93
21	21	0.067	6.3	7.6	1.9	1	23	1188	1211	1188	1211	0.97

Sequence Information

Coding Sequence: ATGCTGTTCAAGGGGAACAGCTCGAGACTTGAGCTGCTAATAGGGAAGATCCAGGCGCATAAAGAACCCTCGCAGGACGAGCAACATAAATCCAAAGAAGCCCTAGGAACCGGTAGTTCCTCGTGGCACAGCGAGGATGGTGGACCCCCATCGCGCCGTGGTGGCGAGACACCCTCGTCCTGTGCGACCCCGACGTCCGCAAGTTTCGCGTCGGAGCCAGAAGCTGACGCCGAGGTCAGTGTCAATGCCGACGGTAACGTCGCTGCGGCGCCATATCCCTGCCAATTCTGCGAGTGCACCTTTCCTCGATTGAGCTACCTGAAGAAGCACGAACAAAGTCATGGAGACCAAATGCCGTACCGGTGTAGCTGGTGTTCGCGATTATTCAAGCACAAGCGCAGCAGGGACCGACACGTTAAACTCCACACGGGCGACCGGAGATATCGGTGCACCCACTGCGAGGCCGCCTTTTCCAGGAGCGATCACCTGAAGATCCATATGAAAACTCATGACACTCAGAAGCCGTATCAGTGCACGGCATGCTCTCGCGGTTACAACACGGCTGCAGCGTTAACATCCCACATGCAGTCACACAAGAAGCACCACCAATCATCGTCGCAAGGAATGATGAAGCTTCAGGATGTCGATTACGGACGAAGAAGCGTATCATCGCATAGCACGTCCTCCCCACCGGTGGCAAACTCACCCTCGCCATCCCTCAATCTGACCTTAAACCCAAAGGCACCGTTGAAGTCGTCACAAGGCACCTGCAGTTCCTCGACGACGCCAATTCTCAATTCACCCCTGAAGCTCGCTTGCATGTACTGCACGAGAGACTCGTTCAGCTGTATGCAACAGCTGCAGATGCATGTGCACACAATGCACCAAGCGATCCTAAGCGGAGAGGGGCTGACAATACCACCATCGCCAAATAGACCAAGCGAGCAAGTGTCAGCATACCAACGCGATAAGGTTCACGATCGTTCGGAGAGCTCAGTCAAGGAGCACGAAAGGAAGTATCAGGAGGATCCAGAGAGACGCTTGGACAAGGAGCACTACGATAACGCTACGTTTACCTGTAATCAGTGTacaatgaaattttccacGTTGGGTTCTCTGCGAGATCATCTGATTTCGATTCATCGGACTGATGGTTTTGGATCAGCCTTAATGATGTGTCCCCTTTGTGGCATTCCTTGCCCTTCGGCCGCGGCCTACGCCGAACACTACGTTCTCCAGCACTGCGAGAATCGCAGAATGAGCCCACTCGATACGCGAGAATACGGAGAAACCAAGCTAAATGGGCTGTACGACTCGAAGAGCGCGAGATTCCAAAAAAACCGGGAACAGATCTCAGAGCCGGCTGATCTGACCAGCAAAAATCAGAGATCAACGGAGAGCAGTTATACGTCGGGGACATTGCTTTGTGGACAATGCGGAGCAGCCTTGAAAGATTTTGAATCATTTCGAGAACACGTGGCTAGACATCTCCAAGCGGACCACCGAACCGAAGTGACTAGGCACCCGTGTCCGAAATGCGATGCTTCTTTCCAAGACAGAGAAGACATGCTGGGTCATCTGACTAAGCACTACCTTGGTCAGATCACCAAGGAGTATGCTTGTGGCGCATGCAAGAAGCTCTATCCTCATCCGGATCTTCTGCAGAGGCACTTGTTGGATAGTCATGCCCATCATTTGTACAGATGCGCCCTGTGCAGAGACACCTTTGACTCGCGGGTCGCCATACAAGTACACTTCGCGGTGAAGCACAGTCAGGAATGTAGGATTTATCGGTGCAATGCGTGCACGGTCTCCAACAATGAGAACTCGCCGGGTAATGCACCTGGAGAAGGGAGAAGCTTCTTCCGAAGCGAAACTGAAATGGCAAACCACGTAAGAACTGTCCACGCACCGTCGTCATTGTCGAGCAACAGCCCCATCGTGAGAAGTCCGGCTTCGACTCCCGGAGTTACGGTGCCTCCTGGACCAAGATGCGTTTTCTGCGGAATATACTGCACTTCCGAACTCGAATTGCAGCTACATTTAGCCAGCCACTCGACTAGTTTGTACAGATGTCCAATCTGTAGAGAAGGATTCGCTGTCGAATTTCTGCTCGACCGCCACCTCGCTCAGGTCCATCAATCTACCGATCATCAACCAATCGTTAGAAGCAGCTCCAGGGAAAATGGTAGAATTCCTAGACCGCCTAGGTATCAAGAGGAAGTGAAGACGCAAAAACGAGGCCGCTCGCCAGCGTCCAGTAACAATAACTCCCTAAATCAACGggacaacaacaacaaaaggCCGAATTACGGTAGTTCGGTGCAACAGTGCGAACTATGCGAAAGAGGCGAGTTTGCGAATGAAGCCGAGTTACAGGCGCACAAGAAATTAGTGCATGCACCGTCAAAAACTCCTAATAAATCATTGTCGAGCTTGAGTATGACGTGTGCTTACTGCGGAGAGGTTTGTCGCTCGAGATCCGAATTGGAGTCACACACGAGGATTCAACATGCATCGAACGAACCAGGAGGACGTCACAAATGCAATATTTGTGACGAAGTTTGTCCATCGGGAGCTATCCTAGCCGAGCATAAGCTACAGAAACATTGTAAAATTCGACTGAGCGACACTTGCGTAGTGTGTCGAAATTCACTCTCTTCCGAGAGTCAATTCCTCGAACACGTTCAGAGACACAGTCTTGAGAGCGTTGATCCTCAGCAAAGATTGGACAGTTCCTTGCCGCATCTTCCGGCACCGTGCGTAGTCTGCAGGCAGACATTGATCAGCGAGCTAGAGTGTCGCTTGCACGCGCGACATCATCTACGAGCACCTACCGGTTCCCAGAGTTCAGCTTCTAGTCCAAGTCCCAACCAGAAAACACAGAGTCCAGGCTGTTGTCTGTGTCTAAGAGATTTCTCTGGCGAAGACTTTGTCAGTTTGCCACCGAGTCACGTTAGTGGTACAGGCCAGTCCTTGAAAGTCTGCAAACCTTGCTACATACGACACTCGCAAGGTTTGCCTATTTTAAATCCAGCGTATGAACATACCGGAGGAACCACCAAAACTGAACAAGCTTGGATCATGAGCAAGGAATCCCATTGGGAGGCTCCGAAAGACAGATGGGAACAAGATAGAGGATTTAAGCCGGAGGATAGATCTGGTACTGAGCCAGATTCGGATAGTAAGAGATGTCAAGACTGTGGAGTCAAGTTCGAGGATCCTGAAGAAATGGAGAAACATCGACTTGCCGAACACGAAAAGATCGACCCTAATACCTACACCTGCATTCAATGCCAGATGTCCTTCCCGAGCGAAGTGGAAATTCAGCAGCACGTGAGGCAGGAGCACTTGGAAAGCTCAGGAAAAAAGTCAGAGGCGTTGCGCTGTCATTTGTGTCTTTTTGAAGCTGCTAGTCCTTTGCAACTGCAAAGTCACTTGATAGAGCATACGTTTGCGGGTTGCGCCGCACTCAGCTGTTACATTTGCCAGTCGCTTTTTACTGCACCGATCGGTCTACAGAATCACATGCTCCAAGAACACGGACTCGGCGCACGGCCTTACGATTGCACACGCTGTccattaaaattcttcttccgCGCCGAACTGGATCATCACGTGCTCACGTATCACCGTGCGAACGAAGAGTCCCAGCCGGTTAACGCGGAAATGAAGACTTCAGAGAAGAAGGACGAGAGCGAAAAAGCAGTGAGAGTGAAGGAAGAGACGACAGCTGTAATTGCTGACGATGAGGAagccgaggaagaagaggaggaagaagaagaagaagtagaagaagatgaagaagaagaagtgaaTGTTGACGGACAAATAGATCAAGAGGAAAACGATacaaataaagaaatagaTTCGAGACCTGTCGCAGAAGCTGAAGATAAATTTAAGGAAAAGGACTCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSQDEQHKSKEALGTGSSSWHSEDGGPPSRRGGETPSSCATPTSASFASEPEADAEVSVNADGNVAAAPYPCQFCECTFPRLSYLKKHEQSHGDQMPYRCSWCSRLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSSSQGMMKLQDVDYGRRSVSSHSTSSPPVANSPSPSLNLTLNPKAPLKSSQGTCSSSTTPILNSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGEGLTIPPSPNRPSEQVSAYQRDKVHDRSESSVKEHERKYQEDPERRLDKEHYDNATFTCNQCTMKFSTLGSLRDHLISIHRTDGFGSALMMCPLCGIPCPSAAAYAEHYVLQHCENRRMSPLDTREYGETKLNGLYDSKSARFQKNREQISEPADLTSKNQRSTESSYTSGTLLCGQCGAALKDFESFREHVARHLQADHRTEVTRHPCPKCDASFQDREDMLGHLTKHYLGQITKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVSNNENSPGNAPGEGRSFFRSETEMANHVRTVHAPSSLSSNSPIVRSPASTPGVTVPPGPRCVFCGIYCTSELELQLHLASHSTSLYRCPICREGFAVEFLLDRHLAQVHQSTDHQPIVRSSSRENGRIPRPPRYQEEVKTQKRGRSPASSNNNSLNQRDNNNKRPNYGSSVQQCELCERGEFANEAELQAHKKLVHAPSKTPNKSLSSLSMTCAYCGEVCRSRSELESHTRIQHASNEPGGRHKCNICDEVCPSGAILAEHKLQKHCKIRLSDTCVVCRNSLSSESQFLEHVQRHSLESVDPQQRLDSSLPHLPAPCVVCRQTLISELECRLHARHHLRAPTGSQSSASSPSPNQKTQSPGCCLCLRDFSGEDFVSLPPSHVSGTGQSLKVCKPCYIRHSQGLPILNPAYEHTGGTTKTEQAWIMSKESHWEAPKDRWEQDRGFKPEDRSGTEPDSDSKRCQDCGVKFEDPEEMEKHRLAEHEKIDPNTYTCIQCQMSFPSEVEIQQHVRQEHLESSGKKSEALRCHLCLFEAASPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCTRCPLKFFFRAELDHHVLTYHRANEESQPVNAEMKTSEKKDESEKAVRVKEETTAVIADDEEAEEEEEEEEEEVEEDEEEEVNVDGQIDQEENDTNKEIDSRPVAEAEDKFKEKDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00391507;
90% Identity: -
80% Identity: -