Basic Information

Gene Symbol
-
Assembly
GCA_029032895.1
Location
JARDWC010000438.1:1290408-1292012[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 1.7 1.5e+02 3.7 3.8 2 23 214 236 213 236 0.89
2 10 0.00024 0.021 15.8 0.7 1 23 242 264 242 264 0.98
3 10 0.012 1 10.5 4.0 1 23 270 293 270 293 0.96
4 10 0.00014 0.012 16.5 0.3 2 21 300 319 299 320 0.93
5 10 0.0016 0.14 13.2 7.0 2 23 342 363 341 363 0.96
6 10 1.1e-06 9.8e-05 23.1 2.4 1 23 370 392 370 392 0.98
7 10 0.00011 0.0099 16.8 0.5 1 23 398 420 398 420 0.98
8 10 5.8e-06 0.0005 20.9 2.1 1 23 426 448 426 448 0.96
9 10 2.5e-05 0.0022 18.9 3.2 1 23 454 476 454 476 0.98
10 10 1e-05 0.00092 20.1 3.3 1 23 482 505 482 505 0.98

Sequence Information

Coding Sequence
atgacTAATGTTGATAAATACTGTCGGTTGTGCGCCGAACTGACAGAACAGCTAATATACGCTGACGAAGCGGCCGCGATAAACTCAAAACTTGCAAACAAAATGTTGTGGATAAACGTTGATGTTTCTCCATCAAATAATCTACCCAAAAGTATATGTTACTCATGTTTTGATCAATTAGAACGCACTTGGATATTTCTACATAACGTGCGTGAAGCGCAGACAAAATTGATTCAGATATTCACTACAAACACTGAACATAATAGCACATTGAAGAATAACTGTTCCGATGTAGGTACTCCAGTTGATATGAATTGGGATGACTTTCAGAAGGTAAAGGTTATAGTAAAAAATGAAGATTCAGCAGAAAAAGTTAACACCATTGCTATACTTGATGCAAGTAAATTTATCGATGGTCTTGGAGGTATTAAGGCTGAAAGGAACAGTAAGGACGATATGCATGACACTGGAGCAGATACCGATGATTTTATTAGCACTGACAGTGATATACCTTTGTTCAAAACGGCTAAAAAGAAAAGGGCAAAAAGAAAAGCGTCACAACAATTAGACAACAATGCAATACACTTAGAACCAGTAGATATTTCTACACTTGATATAACATGGGATGAAGAGGCCTGTCGCTGTGGTTACTGTGATGCACAATGTAAAAATATTGCATTGTTGAGGTTACATTCCCTGCATATACACAACCGCTGTTGTATTTTTAAGTGTGTAGAATGTGGTAAGATTATaacaaactttaaattatttgtgaaCCACATGCGACTGCACAAACCAATGCTCAATTACTGTTgtgaaatttgtaataaaaagttCACAATGATTCAATACACGAAGAGGCACAGGAACATTGACCACAgtagtattaatttaattagttgcAGAAAATGTGGTACAAGCTTTGACTCTTTAGGACATTTACAAGATCACATGGaatcatataataaaagcttCAAGAGAACAAACAGGAAGCAGTTTGATGGTTTGGGAGAACAGGATCTTAAGTGTAATCATTGCTGTAAGGAGTTTAAAACTCGCAGTAACTTGCAACAGCATAAGCTTGTGCACACTAATCGGCGAAGGGATTTCTCTTGTCATATATGTGGTAAAATGTTCTTTACTAAGGGTACTTTAAGCTCTCATATACTAACTCATGAAGACTCTAAGCCTTATAAGTGTGAATTTTGTTCAATGGCATTTAAGGCGAGAGGCAACTTACAATCTCATATAAGTTTACATTCTGGTGCAAAACCTTTTGTATGTGAACAATGTGGGAAGAGCTTTAGAGTAAAAAGACACTTAAAGTCTCATTCAATTGTCCACACAGATCTAATGCCATACATATGTGAATATTGCAATAAGACATTTCGCTTTAAAACACGCCTCAATTTGCACCTGCGTCAGCACACTGGTGCTAAGCCATATCGTTGTGACATGTGCCAGAGAGACTTTACAAATGGTTCAAATTATAAGAAACATATGAAAAGGAGGCATAACGTTGACACATCATCAAGGAAAAAGTATCAGAGTGCAACTAGTGAAGGAACTGAAGAAACCAAGGATAATAACATAGAACAGACATGA
Protein Sequence
MTNVDKYCRLCAELTEQLIYADEAAAINSKLANKMLWINVDVSPSNNLPKSICYSCFDQLERTWIFLHNVREAQTKLIQIFTTNTEHNSTLKNNCSDVGTPVDMNWDDFQKVKVIVKNEDSAEKVNTIAILDASKFIDGLGGIKAERNSKDDMHDTGADTDDFISTDSDIPLFKTAKKKRAKRKASQQLDNNAIHLEPVDISTLDITWDEEACRCGYCDAQCKNIALLRLHSLHIHNRCCIFKCVECGKIITNFKLFVNHMRLHKPMLNYCCEICNKKFTMIQYTKRHRNIDHSSINLISCRKCGTSFDSLGHLQDHMESYNKSFKRTNRKQFDGLGEQDLKCNHCCKEFKTRSNLQQHKLVHTNRRRDFSCHICGKMFFTKGTLSSHILTHEDSKPYKCEFCSMAFKARGNLQSHISLHSGAKPFVCEQCGKSFRVKRHLKSHSIVHTDLMPYICEYCNKTFRFKTRLNLHLRQHTGAKPYRCDMCQRDFTNGSNYKKHMKRRHNVDTSSRKKYQSATSEGTEETKDNNIEQT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01130226;
90% Identity
iTF_01130226;
80% Identity
-