Basic Information

Gene Symbol
-
Assembly
GCA_033220335.2
Location
CM067280.1:1273813-1279223[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.11 11 7.4 4.1 2 23 37 58 36 58 0.93
2 14 0.18 17 6.7 5.8 1 19 66 84 66 89 0.88
3 14 8.3e-06 0.0008 20.4 2.6 1 23 95 118 95 118 0.98
4 14 0.0002 0.019 16.0 0.7 1 23 120 142 120 142 0.96
5 14 0.071 6.8 8.0 0.2 1 23 177 199 177 199 0.97
6 14 0.32 30 5.9 1.7 1 14 257 270 257 275 0.81
7 14 0.00043 0.041 15.0 1.4 1 23 285 308 285 308 0.93
8 14 0.0056 0.54 11.5 3.5 2 23 320 342 319 342 0.95
9 14 0.0049 0.47 11.6 0.7 2 23 348 371 347 371 0.96
10 14 0.83 80 4.6 2.8 3 23 378 398 378 398 0.96
11 14 0.0075 0.72 11.1 0.5 1 20 403 422 403 425 0.92
12 14 0.0048 0.46 11.7 0.5 1 23 431 453 431 453 0.97
13 14 8.8e-07 8.4e-05 23.4 4.5 1 23 459 481 459 481 0.99
14 14 5.1e-05 0.0049 17.9 2.1 1 23 487 510 487 510 0.98

Sequence Information

Coding Sequence
ATGGCTTCACCCACTTATTTAGGTCTAGCTAATGAGATTCTAGCAAACTCATCCAAAGCTGAACAATATGGCATAAAGCTCACAACCATTGATTTAGTTGGAGGAATTCACTGCCATATTTGTAGTacaacatttaaaaacaaaaaggtTTATGACACTCACTACATTCTGCACGAGACTGGGACTGGAATTGTTTACACATGTGTTGTGTGTCATAAGAGCTTTAACCGTTATCCCAGCTTCAGAGGCCACTGTTATACTAATCATGTGATGAAGGCCAAGtacaaGTGTGAACACTGCAAGAAACAGTTCTCCAAACTGACCGCCCTGAAAAATCATATCAATATTATACACAAGTTTATATGTACCACATGTGGCAAAGAATTCCAAACAAAGAAAGAAATGCAAATTCAtaagataatacataataatagtgACAGTCCACCTTACGAATGTCAATCCTGTCAAAGGAAGATTGACAGCTTGGATGGTTGCGAATACCACATTGATCTGCATTTATCATTCACTTACTTCTGTCCCATCTGCAGCGAGAACAGCAACAGTAAGCAAACGATCCTTGAACATCTACAGATACACTTTGATGGAGCAAGCCAAGATAAGTCAACAATAGAAATTGTGGAAACGCATGAGGATGAGTTTATTGAAAAGCTTGGTGGAATACTTTGCTGCGTTTGCTCCACGGTACACAATAACCGCGTAAAATTCGATGCACATTTCTCGCAGATGCACGGCTCTGAGGATATTGTGTACACATGCAAAGAGTGCTCTAAACAATTCGACAAGTACTCTGTGTTTGGCAGCCACTGCTACGACCACTGCATGAAGAACAGATTTGAATGCGAACACTGTAGCAAGACGTTCCCGCGCATGTCGCGGTTGGCGGCGCACAAGGAGTTGTACCACGTGAACCTCCTGTCTTCCGGCCCGATGCCTTTACAGTGCCCTCGCTGTGAGCACCAATTCACGAAGCACAAAGCATTGCAGGAGCATCTGCGCGAACAGCACAGCATCACCTGTGTCCAGTGCCCCCATGAGGGTTGCGAAAGAACTTTCGAAACACCAAAAGAACTGGTCTTCCATCAACGTAAACACGACAACTCGGAGAACTGGTGCCGTCGATGCGGACTTTTGTTCTCTACACGATCATCCTGCGAAAAACATCTAGATGTACACAGGAAGAAATCTTTCTCGTGCCCAATCTGCAACAGGAATTACGCGGAGAAGCACTTGGTCATCAAGCATATCCCAAAACATTTCGAGGCTGTTGTCCACATCTGCAAGGTGTGCGGAATGATATACAACGCCAAGAACCGTCTCATCCAGCACATCAAAATCCATTCAGAGGTTAAGACCTACACCTGCTCACACTGCGGCAAGGGTTTCGTCAAACCCCATCACCTGGAGCAACACATGAACATCCACACTGGAGTGAAGTCATATAAGTGCGCCAGTTGTCCGAAAACATTCGCGAGCTACGCCAATTTGCACAAACACTCGCGCAGAATACACAACACACAAACGAAAGACATCAAGAAGGTGTTCACGGAGACGACCAACGAAGCCAATAGTGAAAATTCAACAGACGCAAGCAGCTCCAAAGAGAGCAACGTTAAATTGGATACGGAAATGAATAAATCCAATGGTACTTCCAGTACCAATACATCAGAAACTGATTTGATGTCATATAAATTTGAGCCAGATGACAGCGCAATAGAGTCGGACAGTATTGATCCTGTTGTCATTAAGAAAGAGCTGAAAATATTTGAAGCTATTGACGACACACTCTGCTTTCCAGAAGCCCCCAAAGAGTCCCTCGTGACCGATCAACCGGGATCTTCCACCAACCACTATCCGTTGGAGTATGGGCCGGAGTTCAATAACGGTTTTCACACGGATGGCACCGGGTTCATCGATTTTGACGACCACATGCTGCCCCACATCGACCCTCTCCTCACGATCAACAACGACCAGCCCCTCCACACCATGTACGTACGGAGCATACCCGACTACCAGTACCAGAGCTTCAACACAAACATGAACGCAAACTTCAACACGGACAAGTGGGAGCCGATCATAACCAAAGTGTACCAGGACTACACTTGCGGCTACGAGGACATGGTGGACGTAAACCGGTTGTCTGTCATATTTTGA
Protein Sequence
MASPTYLGLANEILANSSKAEQYGIKLTTIDLVGGIHCHICSTTFKNKKVYDTHYILHETGTGIVYTCVVCHKSFNRYPSFRGHCYTNHVMKAKYKCEHCKKQFSKLTALKNHINIIHKFICTTCGKEFQTKKEMQIHKIIHNNSDSPPYECQSCQRKIDSLDGCEYHIDLHLSFTYFCPICSENSNSKQTILEHLQIHFDGASQDKSTIEIVETHEDEFIEKLGGILCCVCSTVHNNRVKFDAHFSQMHGSEDIVYTCKECSKQFDKYSVFGSHCYDHCMKNRFECEHCSKTFPRMSRLAAHKELYHVNLLSSGPMPLQCPRCEHQFTKHKALQEHLREQHSITCVQCPHEGCERTFETPKELVFHQRKHDNSENWCRRCGLLFSTRSSCEKHLDVHRKKSFSCPICNRNYAEKHLVIKHIPKHFEAVVHICKVCGMIYNAKNRLIQHIKIHSEVKTYTCSHCGKGFVKPHHLEQHMNIHTGVKSYKCASCPKTFASYANLHKHSRRIHNTQTKDIKKVFTETTNEANSENSTDASSSKESNVKLDTEMNKSNGTSSTNTSETDLMSYKFEPDDSAIESDSIDPVVIKKELKIFEAIDDTLCFPEAPKESLVTDQPGSSTNHYPLEYGPEFNNGFHTDGTGFIDFDDHMLPHIDPLLTINNDQPLHTMYVRSIPDYQYQSFNTNMNANFNTDKWEPIITKVYQDYTCGYEDMVDVNRLSVIF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01496035;
90% Identity
iTF_01496035;
80% Identity
-