Basic Information

Insect: Trilocha varians
Gene Symbol: zfh1
Assembly: GCA_030269945.2
Location: AP028261.1:12427593-12430487[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0064 0.53 11.5 0.7 1 23 44 66 44 66 0.95

2 8 2.9e-06 0.00024 22.0 2.5 1 23 77 99 77 99 0.98

3 8 1.3e-05 0.0011 19.9 8.8 1 23 108 130 108 130 0.99

4 8 0.00012 0.0098 16.9 1.0 1 21 136 156 136 157 0.95

5 8 0.00028 0.023 15.8 0.8 2 23 416 437 415 437 0.97

6 8 8.8e-06 0.00073 20.5 1.1 1 23 725 747 725 747 0.94

7 8 0.0003 0.025 15.7 10.0 1 23 753 775 753 775 0.98

8 8 0.047 3.9 8.8 8.1 1 21 781 801 781 802 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0064	0.53	11.5	0.7	1	23	44	66	44	66	0.95
2	8	2.9e-06	0.00024	22.0	2.5	1	23	77	99	77	99	0.98
3	8	1.3e-05	0.0011	19.9	8.8	1	23	108	130	108	130	0.99
4	8	0.00012	0.0098	16.9	1.0	1	21	136	156	136	157	0.95
5	8	0.00028	0.023	15.8	0.8	2	23	416	437	415	437	0.97
6	8	8.8e-06	0.00073	20.5	1.1	1	23	725	747	725	747	0.94
7	8	0.0003	0.025	15.7	10.0	1	23	753	775	753	775	0.98
8	8	0.047	3.9	8.8	8.1	1	21	781	801	781	802	0.96

Sequence Information

Coding Sequence: ATGTTTTTGGTGCTCATATCGCAATGTCTTTTGTCAACAGTCCGTCCGCTGGCGGGTGGAGGATCGGAAAGCAAGCCGTCTGAGGAGGAAGAGGACCGGAGTGGCTCGCCCCTCGGACCCGGAGGTCCCTTCACATGCAGCCAGTGTCGCGGCACCTACCCCACCCGGGAGCAGCTGGAGCGACATGAGACTCTGCACACGCCCAGCACACAGGTGGATACAGTCCAATATACATGCAACATTTGTCACAAGAGCTTCGCAAACGTGTATAGGCTTCAGAGGCATATGATCAGCCACAATGAAAGCGCTGATCTTAGGAAATACAAGTGTAATGATTGCGACAAAGCTTTCAAGTTCAAACATCATCTCAAGGAACATCATAGGATTCACAGCGGCGAGAAACCATTCGAGTGCGCTAATTGTGGGAAGAAATTCTCGCACTCTGGCTCTTACTCCAGTCATATGACATCGAAGAAGTGCCTAGTAATGAATCTCAAAATGGGTCGAATAAAACCAAACAATCCGGCTTTGAACCCTAATAGAAGCCCGTCCAGAAAACGAGCTAATGCAATGGTGACATCTcagttaaacaataatttaccaCCCAACGGAAACAGCTTTTTGCCCATTCTACCAAAATACAATGAAGCAGCTGCTTTCTTTGCATCTATGTCATCTCAAGACAGTAGTTTTCATCGTCCACCATTGGGGCAGCCACCACTTAACCCATTTTATTTACCCCCTGGACTACCCATGAGTCCAGCTACTGGCATCACCCCATACAGTTTGAGTCAATTCTTCGAACAGTTAGCATCATCTCAATGTCCTCCGAGAAAAATGGAACAACCTCCTAGTCCGAAGCACTATACTCAAGAAGCTCCCGAAGATCTCATTGAAGAAGTTACTGAAGAAGATGACAAGAGATCAGAAGGAAGTGCTGAGTTGGTCATGGATATTGAGGATGACGAAGGAGTTGCCATTAAAAAAGAAAGAGAAGATCAAGATAGCGACATTAGACCTCCATCTCAATATGATTCCGTCCCATTAAACGGCACAGTTCAAAGTGAGGATAATAATCAATCCAGATTCAATCAAATCTTAGAATCAGTGAGTGCGTCTGTGACGAAACATTTCATTAGTGCCAATGCTGACAAGCTCTCTCCAGTAGCGGGCTCCATATGCCCAAGTTTAGATTCACCTCCACCACCACATGTCATCGTGAAAGAAGAACCTGAAGACATAAATCAATGTTTCAAATGTAACATTACATTTGAAAATAAGAGCGAGTTGTTAGATCATGAGAAAATACATTGCGATAGCATCTTTCGAAAACATGAGAGTTTGGCTGCCCAAGTGGCCGAGACGGTAGCTCTGACAAGAATAGAGGCAGAGATGCGTCATAACGTACAAAGTGGAGCGAGTGCAAGTGAAGATGAAGATTCTAAAAATGATGATAAACTGTCTTTACACGATAATGACAAGAAAATAAGAGTCCGTACTGCACTAACTGATATCCAACAAGCAAAACTGAGGGCTTTCTATTGCTTCAACCAAAGACCGAATCGTGAAGAATCTAATAGTATAGCTCAGCAAGTTGGCTTGGACAGCAGGGTGGTTCAGGTCTGGTTCCAAAACTTTAGAGCCAGACAAAGAAGAATGACGAAAATCCAGACTTCTCCGGACCAACCCTTAGATCTGTCCACTAAGAAGTCAACTCAATCCGTAACCTCGACGCCGTCCCCCTCACCGTGCAGCATTTCAGTAACACATTCCGATTCCGAGGAGGCTGTGAACTTAAGTCAGAAATCGTCACGAAGCACGACGCCCCACCGCACCACCTACACTTACTCACATTCCAACTGCTCATCGTCTTCTTTCACTGACTTTAGACTGTCGCCGTCGCCTGGCGAGATCAACAGCCAGAAACGACTGCTCTCACAAAAAGTTAACCCTTTAGTGCCGATGGAGAAGCTATTGCAGTACAACGACATGGCCAACGGCAGATCTCCAGTCCTAAATATGCTATCGAGTGACGTCACTCGACAGGGAAGCCCATCTTACGATCGACCCTGGGCTGATGACGTTCAGCTTCCCAACGATTATGACGACGAACCAAGTGTACTTAAGAAGAGCAAACTTAAACACGTTGAGATAAAAGAAGGTGAAGGACAATTCGTGTGCGATCAATGTGACAAGACATTTGTGAAGCAGAGCTCCCTTGCAAGACACAAGTACGAGCATTCAGgACAACGTCCGCACAAGTGTCAAGAGTGTCCAAAAGCATTCAAGCACAAACATCATCTAACAGAACACAAGCGACTTCACACCGGAGAAAAACCTTTCCAGTGCTGTAAATGCTTCAAGAAGTTCTCTCATTCGGGCTCCTACAGTCAACACATGAACCACCGGTTCGCGATCTGCAAGCCTTACAGAGAATAG
Protein Sequence: MFLVLISQCLLSTVRPLAGGGSESKPSEEEEDRSGSPLGPGGPFTCSQCRGTYPTREQLERHETLHTPSTQVDTVQYTCNICHKSFANVYRLQRHMISHNESADLRKYKCNDCDKAFKFKHHLKEHHRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPNRSPSRKRANAMVTSQLNNNLPPNGNSFLPILPKYNEAAAFFASMSSQDSSFHRPPLGQPPLNPFYLPPGLPMSPATGITPYSLSQFFEQLASSQCPPRKMEQPPSPKHYTQEAPEDLIEEVTEEDDKRSEGSAELVMDIEDDEGVAIKKEREDQDSDIRPPSQYDSVPLNGTVQSEDNNQSRFNQILESVSASVTKHFISANADKLSPVAGSICPSLDSPPPPHVIVKEEPEDINQCFKCNITFENKSELLDHEKIHCDSIFRKHESLAAQVAETVALTRIEAEMRHNVQSGASASEDEDSKNDDKLSLHDNDKKIRVRTALTDIQQAKLRAFYCFNQRPNREESNSIAQQVGLDSRVVQVWFQNFRARQRRMTKIQTSPDQPLDLSTKKSTQSVTSTPSPSPCSISVTHSDSEEAVNLSQKSSRSTTPHRTTYTYSHSNCSSSSFTDFRLSPSPGEINSQKRLLSQKVNPLVPMEKLLQYNDMANGRSPVLNMLSSDVTRQGSPSYDRPWADDVQLPNDYDDEPSVLKKSKLKHVEIKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPHKCQECPKAFKHKHHLTEHKRLHTGEKPFQCCKCFKKFSHSGSYSQHMNHRFAICKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01490040;
90% Identity: iTF_01490040;
80% Identity: iTF_01490040;