Tvar002033.1
Basic Information
- Insect
- Trilocha varians
- Gene Symbol
- -
- Assembly
- GCA_030269945.2
- Location
- AP028258.1:2327732-2331909[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 5.2e-06 0.00044 21.2 1.3 2 23 149 170 148 170 0.97 2 9 1.8e-06 0.00015 22.7 3.2 2 23 178 199 177 199 0.98 3 9 0.00049 0.041 15.0 0.3 1 23 205 227 205 227 0.97 4 9 2.9e-06 0.00024 22.0 2.2 1 23 233 255 233 255 0.98 5 9 1.9e-07 1.6e-05 25.8 0.2 1 23 261 283 261 283 0.98 6 9 1e-05 0.00085 20.3 2.5 3 23 291 311 290 311 0.98 7 9 3.6e-06 0.0003 21.7 2.3 1 23 317 339 317 339 0.98 8 9 0.0017 0.14 13.3 0.6 1 23 345 367 345 367 0.97 9 9 4.6e-05 0.0038 18.2 4.1 1 23 373 395 373 395 0.98
Sequence Information
- Coding Sequence
- atgtcttcgAATATAGATTTAGATAAAATCTGTCGAACATGCCTATCCGACTCAGGCCCTTTAGCGGATTTGTTTTCCATTTGTTCACCAGATATCTTCAAATATTGTACTTCTGTTGAGATTTCAGAAGGTGATAAGCTACCAAGAAAAGTATGTCAGATGTGTGTTGATTTATTAGACAAATTGTACCAGTTCAAACAGATTGCTATCAAGTCAAATGCAGTATTGAAACATCACATAGAAGCAACGGAAAGAATAAAACGTGAACATGGATTATCAGAAGTGGAATTGCCAATAGCTATACTCGCTGAAGAAATACAGTTTGCTCCATCTACAGATAACAGTTCACATGAAATATTTAGTGTGCCCGTACAAGAAGAGAATAAAGTAAGCAAAAGGTGCAGGAAAAGTGAGGCAATAAAGTTAAAGAAAAAAGTTCGCATGAAATGTCCAAAATGTGATAAAACATTCCAGAAGTATGAAAATTTCGAAGCTCATCTCAGAAACCATTTCGGAAAGAAGCCTGACATAAAATGTGAATATTGTGAGAAAACATTTACGAATTTAAGAAACCTACACAGTCACGTTAGAACTCATACAGGCGTTAGAAAGTACCAATGCCTCACTTGCGGGAAGAACTTTGCCTATCTCAATGTTTTAAAGAATCACGAGTTAATACACGCAGGAGCGAAGAAATATGTGTGTCATATATGCAATGCTAAGTTTATTCAGAGATATAACTTGAAGACACATTTAGATACACACACAAACCAAAAGAAGTACATATGCGGTCAGTGTGGAAAGAAATTCTCTCAACCAGGAAACTTGAAGATACATCTTATTAGGCATTCAGGGATCAAGAATGTTGCATGCCATCTATGTGATATGAGATTTTATGTCAAAAGTGACCTATTCAAGCACATGCGGTCTCACTCTTCAGACAAACCGTTCCCTTGTGATTACTGCGACAAAACTTTCAAGAGCAAAAGTTTTCAAACAGTGCATTTACGTTCACATACAGGAGAAAGACCATACGCCTGTGATTTCTGTCCAAAGCGGTTCATGTCAGGCAAAGACATGCGGAATCATCGCATGATTCACACCGGGGAGCGACCACACAAATGCGCGCTCTGCAACCAAGCCTTCATACAGAAATGTGCTCTCAACAGACATATGAAGAGCCACGACAAAGACGGACAGATCATTGCTGATATTGAAGGGATAGAGCAATCTGCGTTGTCCATTTCATATGCAGCTTGGAACGATGTGTGA
- Protein Sequence
- MSSNIDLDKICRTCLSDSGPLADLFSICSPDIFKYCTSVEISEGDKLPRKVCQMCVDLLDKLYQFKQIAIKSNAVLKHHIEATERIKREHGLSEVELPIAILAEEIQFAPSTDNSSHEIFSVPVQEENKVSKRCRKSEAIKLKKKVRMKCPKCDKTFQKYENFEAHLRNHFGKKPDIKCEYCEKTFTNLRNLHSHVRTHTGVRKYQCLTCGKNFAYLNVLKNHELIHAGAKKYVCHICNAKFIQRYNLKTHLDTHTNQKKYICGQCGKKFSQPGNLKIHLIRHSGIKNVACHLCDMRFYVKSDLFKHMRSHSSDKPFPCDYCDKTFKSKSFQTVHLRSHTGERPYACDFCPKRFMSGKDMRNHRMIHTGERPHKCALCNQAFIQKCALNRHMKSHDKDGQIIADIEGIEQSALSISYAAWNDV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00236050;
- 90% Identity
- -
- 80% Identity
- -