Tdro023808.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Trichopria drosophilae
Gene Symbol
topi
Assembly
GCA_030407085.1
Location
CM059582.1:200105169-200107389[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.026 11 9.0 1.0 1 23 241 263 241 263 0.94
2 16 0.15 61 6.7 5.5 2 23 270 292 269 292 0.95
3 16 0.29 1.2e+02 5.8 0.3 2 21 299 318 298 319 0.92
4 16 2.8e-06 0.0012 21.5 1.3 1 23 326 348 326 348 0.97
5 16 1.8e-07 7.4e-05 25.3 1.1 1 23 354 376 354 376 0.97
6 16 1.1 4.5e+02 3.9 1.0 2 19 388 405 387 409 0.78
7 16 0.16 65 6.6 1.4 2 23 427 448 426 448 0.95
8 16 0.24 1e+02 6.0 0.1 1 23 454 476 454 476 0.95
9 16 0.33 1.4e+02 5.5 3.7 1 23 486 509 486 509 0.96
10 16 0.077 32 7.5 0.0 1 21 523 543 523 544 0.92
11 16 0.035 14 8.6 0.1 1 23 549 571 549 571 0.98
12 16 2.4e-07 0.0001 24.9 2.0 1 23 577 599 577 599 0.98
13 16 0.00016 0.066 16.0 0.4 1 23 605 628 605 628 0.97
14 16 0.016 6.5 9.7 0.4 1 23 634 656 634 656 0.89
15 16 1.5e-07 6.3e-05 25.5 0.5 1 23 662 684 662 684 0.99
16 16 0.0062 2.6 11.0 9.2 1 23 690 713 690 713 0.90

Sequence Information

Coding Sequence
ATGTCAATAGATCCTTCAAATACAACAAATCaagttgataataaaataattccgaATGGACCAATTAACTGGTCATACAATGAATCTCTTTCGGTTGGACATATGGAGCTTGAAGTATCGCAGAAGAAACCAAAGATTGATGTGCAATCTGCATGTAGATTATGTGCACAGAAAGTGATAAATCCTTTCTACATCTACTCTGACTTAGGAGAATCTTTAAAATTAGaacagaaaataaacaattggtTAACAGTCAAGGTGGATAAAACCGATCCGTTACCAAAGCAACTTTGTTCTACTTGTGTTGATAAAGTGATGTGGTCTCACGAATTCAACACCCAATGTCAACAAGCTGAAAAGACACTATCGACAATACTTTTTGAGCAACAGAATTTAAATACATCTGAAATTCTTAATATTGACACTAATTGCGACAAATCATGTCCACTCTGTCTAGAAGGAAGTATGTCGATTATCCCAAGTCCAAATGGTAACGAAACAAACAATGAGTCACTTTTTGAGTCTAATACTGAAAAAGAACCCACCACAGTCGATGAAATGGTTCAATGTGACAATATGCAGGAGGATCCtgtagttttacaatattttgaagataGTCAACAATATCTTAAATGCAATGCCTGCATGAacttatttaatacaaaagaaATGCTCGATTCTCATAAATGTAAACCATCGCTGCGAAACACCTCAAAGCCATACACTTGTTCCATTTGTgacgtaaaatttgattttgaagaaCAATTGAATTTTCATCTTCAGTTCCACAATGGTAACAAGTCTCTATGTtgtgaaatatgtaaaatatcattCTGTAATGAATTGAAGcttttttatcattacaaaCGATACCACTGCAATGAAAAAATAGTCTCGTGCTTACAATGTGGAAAATTATTGGACGACCAAGAGAAACTTAAATTGCATGTATGTGTCGATGGAAAAACAAGATCTCATGTATGCGAAGTATGCAATAAAGGTTTCACCGACAACTACACTTTAAAACGTCATGTTGTGACACACCTACCGGAAAAACCATATAAATGTTCCGAATGTCCAAAAAGTTTTACGCAGAAGTCACGATTGAATAAACACATTGCAGAGCACAGTGTTTCAGTCGATCTGGTTCAAGCAGTTTGGAACTGTTTAGAATGTggtgaaatatttaagaattttgaagaTTCTGAAAATCATTGCAAAATCCACGACAGCGACAGCAAAACAACCTTCAAAGAATTGCATGTGTCAAAACTATTACATTGTGAGTTTTGTAACAGTTACTTCATagatgatgaaaaattaaagattcaTCAAAATTTACACACAGTAGAAAAACCTTACTCCTGCAATAGTTGTAACGCTGTATATAAATCATTTGCAGAAGCAGTAATTCACTGGAAAGAACACGTAACGTCATTCAAAGTTGACATTACATTTGTCTGCGATATCTGCAATAAAGACATGAAGGAATTGTCATTCCTGTACAAACACAAACAGAAATGTCACGAACGCCTTCCTCGCAAGTCAGAAACAGGTGTATTAAAATTTGCCTGCGAATTGTGTGGAAAATTGTTTGACGAAATTGGCGAATTCAATAACCATGAAcgagaaaaatgttcaaaatttcctTGCGATATATGTGGAAGTCTCTTGCCAAGCGTAAATTCTCTTAATGCTCACAAACGAAGACACATTGGCTTAAGACCGTACGTTTGCAACATTTGTGGAAAAAGTTACACTCAATCCAGTCATATGTGGACACACATACGTTTCCATATGGGAATTAAACCGTACGCTTGTGAATACTGCGACCAACGATTCAGCATAAAACCAGATCTATCCGATCATGTCAGGAAGAAACACACAAGGGAGAGACCATTTAAATGTGATGTATGTGGCAAAGCTTTCCTCACTGGCTCTGTATTTTACCAGCATAGACTAATTCATCGAGGAGAACGAAgatacaaatgttacatttgtgACAAAACTTTCACTCGAGCAGAAGCTTTAAATAATCATGTGAAGATTCATACAGGGGAGAAGCCGCACATGTGTAATTTTTGTGGAAAATGTTTTCGACAGAAGGGTGACATGAGAAAGCATTGTAAATCTCAACATTctgaattaaatgaaaattaa
Protein Sequence
MSIDPSNTTNQVDNKIIPNGPINWSYNESLSVGHMELEVSQKKPKIDVQSACRLCAQKVINPFYIYSDLGESLKLEQKINNWLTVKVDKTDPLPKQLCSTCVDKVMWSHEFNTQCQQAEKTLSTILFEQQNLNTSEILNIDTNCDKSCPLCLEGSMSIIPSPNGNETNNESLFESNTEKEPTTVDEMVQCDNMQEDPVVLQYFEDSQQYLKCNACMNLFNTKEMLDSHKCKPSLRNTSKPYTCSICDVKFDFEEQLNFHLQFHNGNKSLCCEICKISFCNELKLFYHYKRYHCNEKIVSCLQCGKLLDDQEKLKLHVCVDGKTRSHVCEVCNKGFTDNYTLKRHVVTHLPEKPYKCSECPKSFTQKSRLNKHIAEHSVSVDLVQAVWNCLECGEIFKNFEDSENHCKIHDSDSKTTFKELHVSKLLHCEFCNSYFIDDEKLKIHQNLHTVEKPYSCNSCNAVYKSFAEAVIHWKEHVTSFKVDITFVCDICNKDMKELSFLYKHKQKCHERLPRKSETGVLKFACELCGKLFDEIGEFNNHEREKCSKFPCDICGSLLPSVNSLNAHKRRHIGLRPYVCNICGKSYTQSSHMWTHIRFHMGIKPYACEYCDQRFSIKPDLSDHVRKKHTRERPFKCDVCGKAFLTGSVFYQHRLIHRGERRYKCYICDKTFTRAEALNNHVKIHTGEKPHMCNFCGKCFRQKGDMRKHCKSQHSELNEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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