Tpra009059.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tricholauxania praeusta
Gene Symbol
NFYC
Assembly
GCA_949775025.1
Location
OX459028.1:150108727-150115986[+]

Transcription Factor Domain

TF Family
NF-YC
Domain
NF-YC domain
PFAM
AnimalTFDB
TF Group
Other Alpha-Helix Group
Description
Diverse DNA binding proteins are known to bind the CCAAT box, a common cis- acting element found in the promoter and enhancer regions of a large number of genes in eukaryotes. Amongst these proteins is one known as the CCAAT-binding factor (CBF) or nuclear transcription factor Y (NF-Y) [1]. CBF is a heteromeric transcription factor that consists of two different components both needed for DNA-binding. The HAP protein complex of yeast binds to the upstream activation site of cytochrome C iso-1 gene (CYC1) as well as other genes involved in mitochondrial electron transport and activates their expression. It also recognises the sequence CCAAT and is structurally and evolutionary related to CBF. The first subunit of CBF is known as CBF-A or NF-YB in vertebrates, and HAP3 in budding yeast. The second subunit is known as CBF-B or NF-YA in vertebrates and HAP2 in budding yeast. It is a protein of 265 to 350 amino-acid residues which contains a highly conserved region of about 60 residues. This region, called the 'essential core' [2], seems to consist of two subdomains: an N-terminal subunit-association domain and a C-terminal DNA recognition domain.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 8.3e-50 3.7e-45 155.8 25.9 18 214 91 294 85 296 0.76
2 5 1 4.4e+04 -13.1 34.4 147 222 254 332 238 344 0.57
3 5 1 4.4e+04 -13.6 58.8 142 268 317 450 301 454 0.67
4 5 1 4.4e+04 -9.0 17.0 209 246 439 476 435 487 0.58
5 5 1 4.4e+04 -29.9 64.9 153 242 476 564 453 582 0.65

Sequence Information

Coding Sequence
ATGTATTCCGGAAACAACAGCAATAAAGCGGCAAGCTCAATGGAAAATACTATTACAGTGACACCTATTAAAATGGACATTGATATGTCGCACGTATATCCAACAACAAGTGTTCCTGTCTCCTCCAACACCATCGCAAATGCTGTTCCATCCAGACGCGCAAACATTGGTGTTACAAGTACTGCACATATGAGCACAAGCACAACTGGAGCAATACCAAAGGAAAAATCTTCTAAGCAACCCCGCCTCACCATACATAAGACACCACCTACCATTGACAATTTCTGGAGCAGCATACTGAGTGATGTCAAAAGTATACAACAAGTCGATGCCAAACATCAGGCTTTGCCACTGGCGCGTAttaagaaaattatgaaattggatgaaaatgcaaaaatgatCGCCGCCGAGGCACCACTACTCTTTGCTAAAGGTTGTGAGTATTTTATACAAGAGTTGACCATGCGTGCCTGGATTCACACTGAAGAGAATAAACGTCGCACTCTACAGCGTTCAGATATTGCACAGGCTATTGCGAACTATGATCAATTTGATTTTCTCATCGATATAGTGCCTCGTGAAGATATTAAGCCATCTTCAAGCTCGCACGGGTCTTCATCTTCACACAATAAAAAAGAGTCGCAAGCAGCGAACGCAACGgccacagcagcaacaacaacatcaacagttTCTGTTCCCACAGCTACTATTAAATTGGAAACACCACAGCTAGTCACCTATGGTACCGTTACGTCCGAAACTTTAGCTGCTGCAGCAGCTGCcgctcaacaacaacaacaacagcaacagcaggcGCAACATCTACAACCAACACAGCAATTACAAATATTGCAACAGCCATCACAAACACATCCACAACAGTTACaatattttataacaatacCAGGTCAACAACATGGTCAACATCAGTTGGTCCAACAGTTACAGTTGCAGCATCAACCGCAGTTACAACAGCAACTTGCAAATGGTTTAACTCTAACTACCACTGCTGGGAATCAACAAATAGCGGGTCTTAATATTGTAGCTCCACAGCAGTTGATTCTGACAGCAGGTCCAAATGGGCAATTGACCGCAACACCGGCACCAACTGCTGCAACaacgcaacaacagcaacatacgGCGTTGTTCCAAAATTTGGCGCAGCAGGTtgtacaacagcaacagcaacagcaattgaGTGGTCAGCAACAGATACAACTGCTGCAACAAGTTGTTACACCCACAGGGGAGTTGACCAATGTACCGATTACAATAACAGCAAATCAACTTAATCTCTTGCGATTGCAattacaacagcagcagcagcaacaagcccaacagcaacaacaacagcagcaagtaATCATACCAGCACATTGCATTAATGCTGGTGCAGCTCAGCAAATGTTGCAACAACTCAGTGCTGCTGGTGGCCAAGTGGCAGCGTCTACAGCAGCAAATGTCAATCCCAACACTATTACAACAACACAGATTGGGCAAACGCTGATACATCACCatccacaacaacagcagcagcaacaacaacaacaacaacaacaacagcagcaacaacaacagcagcagcagcaacaacagcagcagcaacaacaacagcagcagcaacaacaacagcagcagctgcaacaacagcaacaacataatACAAGTGGGGGTGCTAACATTTTTCTAACATCTTCcgcacagcagcaacaacagaacCCCAATTCTGTCGTTTCCACAGATCGCAATCTCGGCAGCACGTATCGCACAAATTGCTAG
Protein Sequence
MYSGNNSNKAASSMENTITVTPIKMDIDMSHVYPTTSVPVSSNTIANAVPSRRANIGVTSTAHMSTSTTGAIPKEKSSKQPRLTIHKTPPTIDNFWSSILSDVKSIQQVDAKHQALPLARIKKIMKLDENAKMIAAEAPLLFAKGCEYFIQELTMRAWIHTEENKRRTLQRSDIAQAIANYDQFDFLIDIVPREDIKPSSSSHGSSSSHNKKESQAANATATAATTTSTVSVPTATIKLETPQLVTYGTVTSETLAAAAAAAQQQQQQQQQAQHLQPTQQLQILQQPSQTHPQQLQYFITIPGQQHGQHQLVQQLQLQHQPQLQQQLANGLTLTTTAGNQQIAGLNIVAPQQLILTAGPNGQLTATPAPTAATTQQQQHTALFQNLAQQVVQQQQQQQLSGQQQIQLLQQVVTPTGELTNVPITITANQLNLLRLQLQQQQQQQAQQQQQQQQVIIPAHCINAGAAQQMLQQLSAAGGQVAASTAANVNPNTITTTQIGQTLIHHHPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQQHNTSGGANIFLTSSAQQQQQNPNSVVSTDRNLGSTYRTNC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00972185;
90% Identity
iTF_00972185;
80% Identity
-