Basic Information

Gene Symbol
-
Assembly
GCA_034770305.1
Location
JAPMIB010000130.1:372337-373947[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.00074 0.027 15.7 0.3 1 23 108 131 108 131 0.92
2 7 0.00022 0.0081 17.3 2.8 1 23 136 159 136 159 0.94
3 7 0.00021 0.0075 17.4 0.2 1 23 164 187 164 187 0.96
4 7 2.6e-05 0.00097 20.2 0.1 1 23 192 215 192 215 0.95
5 7 8.9e-09 3.3e-07 31.2 0.7 1 23 220 243 220 243 0.94
6 7 5.4e-06 0.0002 22.4 0.0 1 23 248 271 248 271 0.92
7 7 0.0027 0.1 13.9 0.2 5 23 280 299 277 299 0.92

Sequence Information

Coding Sequence
ATGGAATCcagtaatttatttaattgtgcTTTTAGAGTGAAAGAGGAGCCTGGCGATATGTTTCGTAGTGAAAATGATGATAGTGAAATGATTGACAAGGAATCCGATTTGGAAAACTTCCAACTTTTACCATTACCTCGAGGTAATTCGaCTCATACTCTTCgaaaatatgaagaaaatcATGAAAGTGAACTTCGCGGCGATGTGAAAATAGTTGTTGAATGTGAAGACATGAAACCCAACATCAATTTATTAACAGTTAAAATTGATGATGATTTTCAACATCACTTGCGAACTGCTAAATATAGCAATGGTATCAAATATGCATGCGATATATGTGGCAAGTTATTTGCTCACAGAATTCATATCAAAGCCCACATCGACGCAGTGCATAATGGTATTACGCATAATtgcgataaatgcgaaaaTAAGTTCTCAAGAAAAAATAGTCTTCAACGCCACATCGATTCAGTGCACAATGGTGTTACGtatgcatgtgatatatgcggcaagacatttttatataaaaataaactcaaaatCCACATTGATATGGTGCACAACGGTATCAATTATGCATGCGATGCCTGTGGAAAGAAATTCTCGATCAAGggtaatctcaaaatccacatggACTcggtgcacaatggtgtcacctACACATGTGATGTATGtggaaagtcattttcacaaaaatcgaATCTAAAAACTCACATGGATGCTATGCACAAAGGTATCAAATATGCATGCGATATATGTGGCAAGTCATTTGCTTACAGAAGTAATATCAAAGCCCACATCGACGCAGTGCATAATGGTATTACGCATAAATTCTATAAATGCGGAAAGATATTTTCAAGTAAGAattatctcaaaatccacgCTGGTACGGAACATAATGGGAACACTCATGCATGA
Protein Sequence
MESSNLFNCAFRVKEEPGDMFRSENDDSEMIDKESDLENFQLLPLPRGNSTHTLRKYEENHESELRGDVKIVVECEDMKPNINLLTVKIDDDFQHHLRTAKYSNGIKYACDICGKLFAHRIHIKAHIDAVHNGITHNCDKCENKFSRKNSLQRHIDSVHNGVTYACDICGKTFLYKNKLKIHIDMVHNGINYACDACGKKFSIKGNLKIHMDSVHNGVTYTCDVCGKSFSQKSNLKTHMDAMHKGIKYACDICGKSFAYRSNIKAHIDAVHNGITHKFYKCGKIFSSKNYLKIHAGTEHNGNTHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01482780;
90% Identity
iTF_01482780;
80% Identity
iTF_01482780;